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에탄올과 토코페롤이 간조직의 지질과산화와 미토콘드리아 산화능에 미치는 영향
최영선(Young-Sun Choi),서경희(Kyung-Hee Suh),조성희(Sung-Hee Cho) 한국식품영양과학회 1991 한국식품영양과학회지 Vol.20 No.5
에탄올과 토코페롤이 흰쥐 간의 지질과산화와 미토콘드리아 산화능에 미치는 영향을 조사하기 위하여 Sprague-Dawley 종 255g 내외의 숫쥐 48마리를 4종류의 실험식이로 3주간 사육하였다. 실험식이는 토코페롤 결핍식이(TDC), 토코페롤 결핍-에탄올 식이(TDE), 토코페롤 첨가식이(TSC) 및 토코페롤 첨가-에탄올 식이(TSE)로서 Lieber와 DeCarli의 liquid diet의 조성을 기본으로 하여 토코페롤 첨가는 리터 당 30㎎으로 하였고 에탄올은 36㎉%에 해당하는 양을 탄수화물에 대체하였으며, TDC군과 TSC군은 TDE군과 TSE군에 각각 pair-feeding 하였다.<br/> 4군간에 식이 섭취량은 같았으나 체중 증가에 있어서 TDE군은 TDC군에 비하여 유의하게 낮은 반면에 TSE군과 TSC군의 차이는 유의하지 않았다. 체중에 대한 간 무게비는 에탄올 급여군에서 유의하게 높았으나 토코페롤에 의한 차이는 없었다. 간 미토콘드리아의 산소 소모량과 ATP 합성율이 에탄올 급여군에서 유의하게 감소되었으며, 토코페롤 결핍시 감소 현상이 더 현저하였다. 간의 과산화지질함량은 토코페롤 결핍식이군에서 증가하였으며 에탄올 급여에 의한 차이는 없었으나, 간의 토코페롤 함량은 에탄올 급여군에서 유의하게 감소되었다. 이는 에탄올의 대사 과정에서 더 많은 토코페롤이 소모되었다고 보여지므로 에탄올은 조직내에서 산화 스트레스를 주었음을 간접적으로 시사하며 이와 같은 현상을 식이에 토코페롤의 첨가로 완화될 수 있었다. To investigate effects of chronic alcohol consumption and tocopherol on lipid peroxidation and mitochondrial respiration 48 male rats of Sprague-Dawley strain were divided into 4 groups. Each group received for 3 weeks one of 4 experimental diets: tocopherol deficient control (TDC), tocopherol deficient-ethanol (TDE), tocopherol-supplemented control (TSC) and tocopherol-supplemented-ethanol (TSE). Composition of the diets was based on the Lieber and DeCarli liquid diet and α-tocopherol was supplemented at the level of 30㎎/liter of diet, and ethanol supplied 36㎉%. TDC and TSC were pair-fed to TDE and TSE, respectively. Increase of body weight of tocopherol deficient-ethanol group was the lowest and the effect was diminished with tocopherol supplementation. Respiration of liver mitochondria was depressed in ethanol-administered groups and the effect became larger with tocopherol deficiency. Hepatic lipid peroxide level was not influenced by ethanol, but hepatic tocopherol content decreased with ethanol treatment. The result indicates that, although lipid peroxide level was unchanged with chronic ethanol consumption, oxidative stress exists in tissues of rats administered ethanol and may be relieved by tocopherol supplementation.
시각적 이미지로서 일러스트레이션의 표현방법에 관한 연구
최영선(Young Sun Choi) 한국디자인문화학회 2008 한국디자인문화학회지 Vol.14 No.3
The literal meaning of illustration is a general term for drawings, photographs, designs used to either help understanding or raise interest in books, magazines, newspaper etc. Today however, the concept of illustration cannot be limited just to these. By its nature, today`s illustration can be referred to all graphic or formative expressions other than symbols or signs among methods and ways that complement visual conveyance functions. In particular, ideas are especially important for ad illustration in order to effectively convey messages to sell products or images to customers. With the development of advertisement, ad illustration is called Essence of advertisement. Ad illustrations full of ideas attract the eyes of public, raise the value of the product the customers to purchase the product. For this reason, ad illustrations are used for sales promotion, the goal of advertisement, and corporate image PR. Moreover, advertisement effects can be optimized perfectly harmonizing advertisement ideas and expression. techniques. For this end, overall knowledge of the product and the capacity to understand this are needed. The purpose of this study is to suggest the direction of effective representation by analyzing the representation method so that it can be the basic data for the researchers who study advertisement illustration as learning. For the research method and scope, the features of representation were examined as the visual images delivered effectively through newspaper advertisement by investigating and analyzing the types and methods of representation, excerpting the works that had unique expressions in newspaper advertisement and books issued since 1990s that advertisement illustration had been emerged as a new concern. As a result of such study, effective image representation in newspaper advertisement should provide independent feeling with simplicity, attention, differentiation, clarity, and shape visually based on free imagination.