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신용운(Yong Woon shin),정원재(Won Jae Chung),김영범(Young Bum Kim),김치열(Chi Youl Kim),주영채(Young Chae Joo),우재순(Jae Soon Woo),김응진(Eung Jin Kim) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.4
Primary malignant melanoma of the esophagus is a rare lesion accounting for only 0.1% of primary esophageal malignant neoplasms and almost invariably neoplasms of adulthood. To be interpreted as primary, a mucosal melanoma should ideally have overlying or lateral junctional change, approximately half of all patients had clinically, surgically or pathologically detected metastasis at the time of diagnosis and very poor prognosis. A 28 years-old-female was admitted because of dysphagia and odynophagia for 6 months. Confirm diagnosis of primary malignant melanoma of the esophagus was made by endoscopic biopsy. The case presented here is of interest because it is the first case in the Korea.
Helicobactor pylori 의 검출을 위한 Ultrarapid Urease Test 의 유용성에 관한 연구
박기수(Gi Soo Park),정석(Seok Jeong),김여주(Yeo Joo Kim),이기훈(Ki Hoon Lee),김선후(Sun Hoo Kim),장재남(Jae Nam Chang),송준호(Joon Ho Song),문태훈(Tai Hoon Moon),신용운(Yong Woon Shin),김영수(Young Soo Kim),주영채(Yong Chae Joo) 대한내과학회 1996 대한내과학회지 Vol.50 No.5
N/A Objectives: A variety of methods have been developed for the detection of Helicobacter pylori in gastric mucosa. However they have a major disadvantage which is the time required or may be limited by expense. It has been reported that changing the incubation condition permitted ultrarapid diagnosis (ultrarapid urease test). We have examined the diagnostic efficacy of ultrarapid endoscopy room test and compard it with other diagnostic techniques in various gastrointestinal diseases. Methods: 110patients were performed gastroduodenoscopy. Alsco, antral biopsy specimens were taken for ultrarapid endoscopy room test' (1minute and 5minute records), CLO test and histologic test (Hematoxylin & Eosin, Giemsa stain). We have determinde immunoglobulin-G titer for Helicobacter pylori. Results: Using histologic test as the gold standard, ultrarapid urease test produced a sensitivity of 85.7% (1 minute record), 91.4% (5minute record) respectively and a specificity of 92.9% (1minute record), 78.6%(5minute record) respectively. The diagnostic accuracy of the test was 87.8% in 1 minute and 5minute record. Conclusion: Ultrarapid urease test is a rapid, inexpensive, easily available and reliable technique for the detection of Helicobacter pylori in endoscopy room.
신용운(Yong Woon shin),정원재(Won Jae Chung),김진희(Jin Hee Kim),한명희(Myung Hee Han),김영범(Young Bum Kim),김기수(Chi Su Kim),김치열(Chi Youl Kim),김경국(Kyung Gook Kim),주영채(Young Chae Joo) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.3
Polyarteritis nodosa, one of the necrotizing vasculitis involving predominantly small and medium sized arteries is rare disease.Polyarteritis nodosa may afiect many organs such as kidney, heart, liver,gastrointestinal tract and muscle, so that non-specific symptorns ate characteristic and diagnosis is very difficult. Gastrointestinal Ivoivement was reported in about 50% of cases, but bleeding complication is rere and results in poor prognosis.Recently we experionced a case of plolyarteritis nodosa complicating massive upper gastrointestinal bleeding, which was diagnosed by pathologic wxamination of stomach apecimen surgically removed.
위, 소장, 대장을 침범한 Peripheral T-cell Lymphoma 1예
김영범,이소현,신용운,김치열,우재순,임형은,최혜란,박찬섭,주영채,김진주 대한소화기내시경학회 1991 Clinical Endoscopy Vol.11 No.2
This article is the case report of the peripheral T-cell lymphoma which involove the stomach, small bowel, and colon. A 40-year-old male was admitted to Inha University hospital because of epigastric pain, diarrhea, and weight loss. He was taken by gastrofiberscopy with biopsy, upper G-I series, colonscopy with biopsy, lower G-I series, ultrasonogram, and abdominal computerized tomogram. Endoscopic picture demonstrated the malignant ulcer in the posterior wall of angle. Sigmoidoscopic picture demonstrated the polipoid hyperemic mucosal edema. In the X-ray & endoscopic findings, the lesion was suspected as lymphoma. Histologically, the lesion was diagnosed as peripheral T-cell lymphoma. Immunohistochemical staining using UCHL-1(pan-T-cell maker) demonstrated the lymphoma as T-cell origin. The patient was treated with the multiagent chemotherapy(Bleomycin + Vincristin + Cyclophosphamide + PDS).
김영신,최새로운,이문희,김인호,주영채,김정택,김철수 대한내과학회 2004 대한내과학회지 Vol.66 No.4
원발성 미분화 심장육종은 그 빈도가 매우 드물고 공격적인 국소진행을 보인다. 그러므로 수술로 완전절제를 하고, 이후 보조적 항암화학요법 또는 방사선 치료를 하더라도 예후는 아주 불량한 것으로 알려져 있다. 저자들은 33세의 여자 환자에서 원발성 심장종양 중 미분화성육종을 확인한 경우로 수술 후 항암화학요법과 방사선 치료를 하였음에도 불구하고 재발하여 진단 후 11개월만에 사망한 증례 보고와 이에 관한 문헌고찰을 보고하는 바 있다. Primary undifferentiated cardiac sarcomas are extremely rare, and typically undergo aggressive local spread. The prognosis of undifferentiated sarcoma is reported to be very poor even if surgical resection, with or without adjuvant chemotherapy and radiotherapy, is performed. Here we present our case of primary undifferentiated sarcoma of the left atrium. A 33-year-old woman presented with a month history of progressive breathlessness and exertional chest pain. Transthoracic echocardiography showed a large mobile mass obstructing much of the left atrium. At surgery a superseptal approach to the atria enabled removal of all the left heart tumor which was attached to the left upper pulmonary vein. Immunochemistry staining revealed the undifferentiated atrial sarcoma. She received three cycles of darcabazine and adriamycin and after three months three was evidence of tumor recurrence. Eleven months later from operation, she died with congestive heart failure.
이관우,홍성빈,주영채,조영업,김명식,김미림,인현호,김경래 대한내분비학회 1996 Endocrinology and metabolism Vol.11 No.2
Hashimotos thyroiditis and Graves disease have been thought to be the autoirnmune diseases having their distinct and separate clinical and pathologic features. Because of the partial and complete simi1arity in histologic feature, it has been hypothesized that Hashimoto's thyroiditis and Oraves disease may be interrelated. Several patients who had been diagnosed as Graves disease showed features of hypothyroidism, and were proven to have histologie features of Hashimotos thyroiditis in their thyroid tissue. Two meehanisms had been suggested to explain tbis phenomenon. One is that the combined Hashimotos thyroiditis in Graves' disease may become predominant with time, The other is that the amount of TSH receptor blocking antibody may increase in the course of Graves disease. Early recognition of these patients would be impartant to estabilish therapeutic plan. Futhermcee, extensive study of these patients would give more understanding of the mechanism of these diseases. Here we report 5 cases of clinically diagnosed Graves disease with pathologic features of Hashimotos thyroiditis or focal lymphocytic thyroiditis(J Kor Soc Endocrinol 11:182 188, 1996).