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신용운(Yong Woon shin),정원재(Won Jae Chung),김진희(Jin Hee Kim),한명희(Myung Hee Han),김영범(Young Bum Kim),김기수(Chi Su Kim),김치열(Chi Youl Kim),김경국(Kyung Gook Kim),주영채(Young Chae Joo) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.3
Polyarteritis nodosa, one of the necrotizing vasculitis involving predominantly small and medium sized arteries is rare disease.Polyarteritis nodosa may afiect many organs such as kidney, heart, liver,gastrointestinal tract and muscle, so that non-specific symptorns ate characteristic and diagnosis is very difficult. Gastrointestinal Ivoivement was reported in about 50% of cases, but bleeding complication is rere and results in poor prognosis.Recently we experionced a case of plolyarteritis nodosa complicating massive upper gastrointestinal bleeding, which was diagnosed by pathologic wxamination of stomach apecimen surgically removed.
뇌하수체 기능 저하증과 원발성 갑상선 기능저하증이 동반된 뇌하수체석(Pituitary Stone) 1예
김영범,정영숙,정민화,김기수,임형은,김치열,조숙 대한내분비학회 1991 Endocrinology and metabolism Vol.6 No.3
The Pituitary calcification, pituitary stone is rare, but occasionally seen in craniopharyngioma, pituitary adenoma and pituitary tuberculosis, and it's endocrine function was variable from normal to panhypopitutitarism. This 26-year-old-female patient showed a finding of pituitary calcification on CT scan, deficiency of anterior pituitary hormones and decreased response to combined pituitary stimulation test except TSH. In thyroid evaluation, she was observed as primary hypothyroidism with positive antimicrosomal and antithyroglobulin antibodies. We considered the another cause of pituitary stone with hypopituitarysm, lymphocytic hypophysitis. Lymphocytic hypophysistis is due to autoimmune pituitary destruction and often occurs with other autoimmune disease such as Hashimoto's thyroiditis and gatric atropy. (J Kor Soc Endocrinol 6:266~270, 1991)
하시모토갑상선염에 동반된 골수를 침범한 ( 병기 4E 기 ) 원발성 갑상선 림프종 1 예
이기업,송영기,박중열,김기수,김상희,공경엽,조재근,추윤호,엄완식,지현숙 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.4
Primary lymphoma of the thyroid is a relatively rare malignant tumor of the thyroid. It is known to be frequently associated with Hashimoto's thyroiditis. In Korea, a few cases of primary lymphoma of the thyroid have been reported and most of these cases were in the stage I E or II E. Recently, we experienced a case of the primary thyroid lymphoma, stage IV E associated with Hashimoto's thyroiditis in a 70-year-old woman who presented with dysphagia and dyspnea due to rapidly enlarging neck mass. She was treated with combination chemotherapy(cyclophosphamide, adriamycin, vincristine and methylprednisolone) and local radiotherapy and achieved partial response with resolution of dysphagia and dyspnea(J Kor Soc Endocrinol 9: 390-394, 1994).
제2형 다발성 내분비선증 (MEN type 2a) 1예
한명희,김진희,김문재,김기수,김삼수 대한내과학회 1990 대한내과학회지 Vol.38 No.6
Multiple endocrine neoplasia type 2a(MEN 2a) is an inherited syndrome characterized by the association of medullary carcinoma, parathyroid hyperplasia and pheochromocytoma. It was discovered that medullary carcinoma of the thyroid produces calcitonin, and the capability of measuring calcitonin makes early diagnosis of a C-cell abnormality possible. Current study of the syndrome is focused on defining the genetic and molecular basis, and recent advances in mapping the MEN 2a gene suggest a deletional mutation in an area near the centromere of chromosome 10. Recently, we experienced a case of MEN 2a in a 33-year-old female patient. She had undergone bilateral adrenalectomy leaving a small amount of the left adrenal cortex, followed by a total radical thyroidectomy. Post-operatively she has maintained normal blood pressure, along with preservation of adrenal cortical functions.