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        비디오 영상 예측과 악교정수술

        조명훈,김동훈,김중한,지국섭,박성만,윤영주,김광원 朝鮮大學校 口腔生物學硏究所 2000 口腔生物學硏究 Vol.24 No.1

        The aim of the investigation was to evaluate the validity of the predictions of a computerized video imaging prediction program(QuickCeph Image Pro^(R)) regarding dentoskeletal and soft tissue profile changes after various orthognathic surgery. With the advance of refined surgical procedures, such as the LeFort I osteotomy and the bilateral sagittal split osteotomy, a combined orthodontic/orthognathic surgical approach for the treatment of dentofacial deformities has become routine. And video imaging is a suitable tool for use in patient presentation. education. and subsequent treatment planning. Video imaging techniques have improved dramatically and are becoming increasingly important to clinicians and patients for communication and visualization during treatment planning sessions. With a little effort, patience, and accurate record-taking. the clinician can use video imaging to enhance the surgical-orthodontic treatment planing and patient communication processes. In this study, we compared the real postsurgical profile and predicted profile b use of machintosh-based program((QuickCeph Image Pro^(R)), and evaluated accuracy of the QuickCeph Image Pro^(R). The result of this study, along with conflicting evidence found in the current literature, lead us to believe that on acceptable soft-to-hard-tissue ration has yet to be developed to accurately predict the postsurgical posture of the profile. The need for various soft-to-hard-tissue algorythmes and accurate soft-to-hard-tissue ratios is imperative to improve the accuracy of video imaging in predicting soft tissue profiles following orthognathic surgery. Additionally, it is recommended that a greater understanding of the nature of the facial soft tissue and its response to changes of the underlying hard tissue bo attained.

      • SCOPUSSCIEKCI등재

        수종의 고정성 보정장치에 따른 유성견의 치주조직 반응

        조명훈,윤영주,김광원 대한치과교정학회 2001 대한치과교정학회지 Vol.31 No.1

        교정력을 가한 후 각기 다른 재료로 제작된 고정성 보정장치를 적용한 경우에 발생하는 치주조직의 재형성과 치유과정을 조직학적으로 관찰하기 위해 건강한 치주상태를 가진 네 마리의 유성견을 대상으로 최초 교정력이 200gm이 되도록 견인 스프링 (sentalloy closed coil springR, Tomy Co., Japan)을 대상 치아에 결찰하여 1주일 간 교정력을 가한 후, 각각의 실험동물에 3가닥 호선인 0.018인치 DentaflexR(Dentarum Co., Germany), 3가닥 호선인 0.020인치 DentaflexR(Dentarum Co., Germany), 6가닥 호선인 0.0195인치 RespondR(G&H Co., U.S.A.)를, 그리고 자가중합형 레진 접착제인 Superbond C&BR를 고정성 보정장치의 재료를 이용하여 보정장치를 접착한 군과 보정장치를 접착하지 않은 군으로 나누어 3주간 적용 후 희생하여 H-E염색군, M-T염색군으로 나누어 광학현미경으로 관찰하여 다음과 같은 결과를 얻었다. 1.0.0195인치 RespondR를 접착시킨 군은 0.018인치 DentaflexR, 0.020인치 DentaflexR, Superbond C&BR를 접착시킨 군에 비교할 때 압박측에서의 거대세포 침윤 감소와 긴장측에서의 신생골 형성 증가가 매우 두드러지게 나타났으며 치주인대는 형태와 배열에서 대부분 정상적인 소견을 보였다. 2.실험 1군의 모든 실험대상에서 압박측 치조골 내부의 괴사골이 관찰되었고, 압박측과 긴장측 모두에서 치조골 표면의 골양조직 및 sharped 섬유의 형성과 치주인대의 재형성 현상이 나타나는 것이 관찰되었다. 3.실험 2군은 실험 1군에 비교하여 압박측에서 거대세포 침윤이 현저히 감소되었고 치주인대는 거의 정상적인 소견을 보였다. 긴장측에서는 수층의 골침착을 보이며 치주인대 측으로 골양조직과 골아세포가 구상으로 나타나는 활성화 소견을 보였다. 이상의 결과에서 더 여러 가닥이 꼬인 6가닥 호선인 0.0195인치 RespondR(G&H Co., U.S.A.)를 보정장치로 적용한 경우가 다른 재료의 고정성 보정장치보다 더 활발한 신생골주 형성의 활성화 소견이 관찰되었으며 대조군과 유사한 배열과 형태를 보이는 정상적인 치주인대 섬유의 배열양상이 관찰되어 다른 재료들에 비교하여 치주조직의 초기 재형성과정을 더 신속하게 유도하는 것으로 사료된다. The purpose of this study was to evaluate the material for fixed type retainer, allowing physiologic tooth movement. and proper remodeling of periodontal tissue during retention period. The present study was performed to observe the histologic changes of periodontal tissue after application of different types of fixed type retainer after orthodontic tooth movement in young adult dogs. For this study, 4 young adult dogs were used as a experimental animal and experimental group was divided into three groups ; experimental group 1 contained right side maxillary third incisors and canines, experimental group 2 contained contralateral teeth of same animals, and control group contained mandibular premolars. And each dogs were applied the 4 different types of fixed type retainer to experimental group 1. The experimental teeth were ligated on the Sentalloy closed coil springR(Tomy Co., Japan) from maxillary third incisors and canines and applied orthodontic force at initial 200gm-forced during 1 week. All the experimental animals were sacrificed on the 3rd week after the orthodontic teeth movement and then the specimens were taken, fixed in formalin, embeded in parafin, sectioned 6-8μm in thickness and stained with Hematoxylin-Eosin staining, and Masson's trichrome staining method. Examined under the light microscopy. The following results were observed. There were observed that decreased infiltration of giant cells in pressure side and increased the new bone forming in tension side on the specimen of 6-stranded 0.0195' RespondR(G&H Co., U.S.A.) group. Periodontal ligament fibers were much compressed or elongated in 3-stranded 0.018', 0.020' DentaflexR(Dentarum Co., Germany), and Superbond C&BR(Sun Medical Co., Japan) groups. 2. In experimental group 1, necrotic bone inside the alveolar bone of pressure side, forming of the sharpey's fiber in osteoid tissue, and remodeling of the periodontal ligament were observed in all animals. 3. In experimental group 2, it was observed that the amount of bone resorption was equal or decreased in pressure side, and increased new bone forming and significantly decreased Infiltration of giant cell than the experimental group 1. By this results, it considered that 6-stranded RespondR(G&H Co., U.S.A.) wire was the most useful material allowing early periodontal tissue remodeling.

      • Methicillin 저항성 포도구균의 β-Lactam계 항생제 함유배지에서의 증식 양상

        조명훈,김광혁,장명웅 고신대학교 의학부 1992 高神大學校 醫學部 論文集 Vol.8 No.2

        Methicllin-resistant Staphylococcus aureus(MRSA) has become a major pathogen in patients with nosocomial or community-acquired infections. In the present study, we examined the minimum inhibitory concentration(MIC) and maximum bactericidal concentration(MBC) of methicllin, oxacillin, cefatrizine and tetracycline on MRSA, then followed growth patterns of MRSA and formation of L-form at the respective MIC for various strains to elucidate the mechanism of paradoxic effect of penicillin antibiotics on MRSA. Following results were obtained 1. In twenty strains of MRSA, the MBC of methicillin equal to MIC was 15%, the MBC two fold greater than MIC was 60%, the MBC three fold greater than MIC was 20% and the MBC four greater than MIC was 20%. 2. With oxacillin, the MBC with equal to MIC was 10%, the MBC two fold greater than MIC was 50%, the MBC three fold greater than MIC was 20% and the MBC four fold greater than MIC was 20% 3. With cefatrizine, the MBC with equal to MIC was 10%, the MBC two fold greater than MIC was 60%, the MBC three fold greater than MIC was 20% and the MBC four fold greater than MIC was 10%. 4. With tetaracycline, the MBC with equal to MIC was 10%, the MBC two fold greater than MIC was 55%, the MBC three fold greater than MIC was 25% and the MBC four fold greater than MIC was 5%. 5. In all strains of MRSA showing a paradoxical effect of methicillin, growth was significantly more with 0.5xMIC than with 1xMIC in using Muller- Hinton. 6. In some strains of MRSA, the paradoxical effect was observed at 0.5xMIC in the 50% serum containing Muller-Hinton broth. 7. The paradoxical effects of oxacillin and cefatrizine occurred at 1xMIC in Muller-Hinton broth and at 0.5xMIC in 50% serum conataining Muller- Hinton broth. 8. With tetracycline, the paradoxical effect was not observed both in Muller-Hinton broth and 50% containg Muller-Hinton broth. 9. MRSA strains formed L- form in the media containing 0.5xMIC of methicillin, oxacillin, cefatrizine containg agar, but not in tetracycline containing agar. These results indicate that in some strains of MRSA paradoxical effects of methicillin, oxacillin, and cefatrizine can be observed at 0.5-lxMIC, and this is due to the formation of L-form bacteria.

      • Methicillin 저항성 포도구균의 β-Lactam계 항생제 함유배지에서의 증식 양상

        조명훈,김광혁,장명웅 고신대학교(의대) 고신대학교 의과대학 학술지 1992 고신대학교 의과대학 학술지 Vol.8 No.2

        -Abstract- Methicillin-resistant Staphylococcus aureus(MRSA) has become a major pathogen in patients with nosocomial or community-acquired infections. In the present study, we examined the minimum inhibitory concentration(MIC) and maximum bactericidal concentration(MBC) of methicillin, oxacillin, cefatrizine and tetracycline on MRSA, then followed growth patterns of MRSA and formation of L-form at the respective MIC for various strains to elucidate the mechanism of paradoxic effect of penicillin antibiotics on MRSA. Following results were obtained 1. In twenty strains of MRSA, the MBC of methicillin equal to MIC was 15%, the MBC two fold greater than MIC was 60%, the MBC three fold greater than MIC was 20% and the MBC four greater than MIC was 20%. 2. With oxacillin, the MBC with equal to MIC was 10%, the MBC two fold greater than MIC was 50%, the MBC three fold greater than MIC was 20% and the MBC four fold greater than MIC was 20%. 3. With cefatrizine, the MBC with equal to MIC was 10%, the MBC two fold greater than MIC was 60%, the MBC three fold greater than MIC was 20% and the MBC four fold greater than MIC was 10%. 4. With tetracycline, the MBC with equal to MIC was 10%, the MBC two fold greater than MIC was 55%, the MBC three fold greater than MIC was 25% and the MBC four fold greater than MIC was 5%. 5. In all strains of MRSA showing a paradoxical effect of methicillin, growth was significantly more with 0.5xMIC than with 1xMIC in using Muller-Hinton. 6. In some strains of MRSA, the paradoxical effect was observed at 0.5xMIC in the 50% serum containing Muller-Hinton broth. 7. The paradoxical effects of oxacillin and cefatrizine occurred at 1xMIC in Muller-Hinton broth and 0.5xMIC in 50% serum containing Muller-Hinton broth. 8. With tetracycline, the paradoxical effect was not observed both in Muller-Hinton broth and 50% containing Muller-Hinton broth. 9. MRSA strains formed L-form in the media containing 0.5xMIC of methicillin, oxacillin, cefatrizine containing agar, but not in tetracycline containing agar. These results indicate that in some strains of MRSA paradoxical effects of methicillin, oxacillin, and cefatrizine can be observed at 0.5-1x MIC, and this is due to the formation of L-form bacteria.

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