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갈조류 지충으로부터 분리한 3개의 Norisoprenoids 화합물
박기의,김유아,정현아,이희정,안종웅,이범종,서영완,Park, Ki-Eui,Kim, You-Ah,Jung, Hyun-Ah,Lee, Hee-Jung,Ahn, Jong-Woong,Lee, Burm-Jong,Seo, Young-Wan 대한화학회 2004 대한화학회지 Vol.48 No.4
우리나라 연안에 널리 분포하고 있는 지충이로부터 3개의 norisoprenoid 화합물들인 (+)-epiloliolide (1), (-)-loliolide (2), apo-9''-fucoxanthinone (3)을 칼럼크로마토그래피와 역상 HPLC를 사용하여 분리$\cdot$정제하였다. 이들 분리한 화합물 1, 2 및 3은 갈조류인 지충이로부터 처음 분리되어 보고하는 것이다. 특히 화합물 1은 비록 육상식물에서 분리된 바 있으나, 해양생물로부터는 처음 분리되어 보고하는 것이다. 분리된 화합물의 구조는 $1^H$ COSY, NOESY, HMQC 그리고 HMBC와 같은 이차원적인 NMR 분광학적인 실험을 이용하여 문헌치와 비교하여 확인하였다. From Sargassum thunbergii which is widely distributed in coastal area of Korea, three norisoprenoids, (+)-epiloliolide (1), (-)-loliolide (2), and apo-9'-fucoxanthinone (3) were isolated by using column chromatography and reverse-phase HPLC. Compound 1, 2 and 3 were for the first time isolated from the Brown Alga Sargassum thunbergii. Particularly, Compound 1 was for the first time isolated the marine organism although it was reported from the terrestrial plant. Their structures have been determined by extensive 2-D NMR experiments such as $^1H COSY, NOESY, HMQC$, and HMBC and by comparison with the reported data in the literature.
기능성 족지장단분석과 X-ray의 골반변위 진단의 비교 연구 - X-ray 촬영 자세 및 평가 기준에 따라 -
이정민,국길호,최보미,정현아,홍서영,Lee, Jung-Min,Koog, Gil-Ho,Choi, Bo-Mi,Jeong, Hyun-A,Hong, Seo-Young 척추신경추나의학회 2010 척추신경추나의학회지 Vol.5 No.2
Objectives: This study was carried out to investigate the relationship of leg length analysis and X-ray finding according to positions and valuation bases on diagnosis of pelvic malpositions. Methods: Twenty-two people who get $33.09{\pm}10.73$ as average were evaluated by leg length analysis and X-ray findings. After measuring innominate measurement(IM), femur head line. distance between S2 and posterior superior iliac spine(PSIS). ilium shadow measurement(ISM), major axis of obturator foramen(MaF), minor axis of obturator foramen(MiF) and distance between off centering measurement and symphysis pubis, those were analyzed. Results: 1. In assessment of posterior rotation malposition ilium(PI), it was showed the best coincidence between leg length analysis and X-ray analyzed by 1M in supine position(11 cases, 50.5%). 2. In assessment of inflare, coincidence index between leg length analysis and X-ray were not good($4.00{\pm}3.03$ cases, $18.15{\pm}13.82%$). And leg length analysis were not sensitive. 3. On the whole, coincidence index between leg length analysis and X-ray were not good(best: 1 case, 45.5%; worst: 11 cases, 50.0%). Conclusions: Results form this investigation showed the relationship of leg length analysis and X-ray according 10 positions and valuation bases on diagnosis of pelvic malpositions. This results are expected to contribute to establish method of assessment in diagnosis of pelvic malpositions.
국내 고속도로 터널조명 환경분석에 의한 평균조도환산계수 재정립
김기훈(Gi-Hoon, Kim),서준교(Jun-Gyo, Seo),장민수(Min-Su, Chang),정현일(Hyun-Il, Jung),김필영(Pil-young, Kim),박광용(Kyang-Wong, Park) 한국조명·전기설비학회 2013 한국조명·전기설비학회 학술대회논문집 Vol.2013 No.11
In this paper, we measured the illumination and luminance after selecting the tunnel 39 sites that are paved the road surface of concrete in korea expressway. And, this value was calculated average illuminance conversion coefficient by the arithmetic mean. As a result, cleaning the luminaires has effect on the rise more illumination than luminance. Change of average illuminance conversion coefficient by traffic is stabilized more than 20,000,000 traffic or more than 4 years of the elapsed year. Therefore, the result is analysed by 11.67[㏓/㏅/㎡] in Korea
한정민,이성은,정혜진,최승배,서형식,정현아,고우신,윤화정,Han, Jung-Min,Lee, Sung-Eun,Jung, Hye-Jin,Choi, Seung-Bae,Seo, Hyung-Sik,Jung, Hyun-A,Ko, Woo-Shin,Yoon, Hwa-Jung 대한한방안이비인후피부과학회 2017 한방안이비인후피부과학회지 Vol.30 No.1
Objectives : This study was performed to review the overseas clinical research trends on the effect of On cheong eum on skin disease. Methods : We searched articles in the Pubmed using keywords "On cheong eum", "On sei in", "Wen qing yin", "Jie du si wu tang" and "Jie du si wu decoction". We also searched in the China National Knowledge Infrastructure(CNKI) using key words "???" and "解毒四物?", We selected 5 studies after excluding non-clinical or unrelated studies. Results : One pre-post comparison study and four controlled clinical trials were performed. On cheong eum and modified On cheong eum were used for the treatment of skin disease-recurrent aphthous ulcer, psoriasis vulgaris, neurodermatitis, and skin pruritus. All of the studies showed positive results, and they reported that the treatment group had higher effective rate than control group. However, the quality of these clinical studies were not evaluated. Conclusions : According to this study, On cheong eum would be an effective and safe intervention in skin disease. Therefore, based on this study, more clinical research using On cheong eum should be performed in Korean medicine in the near future.
펜타미딘으로 치료 받은 후천성 면역 결핍증 환자에서 발생한 저혈당 1예
송기호 ( Kee Ho Song ),황용 ( Yong Hwang ),최홍석 ( Hong Seok Choi ),기현균 ( Hyun Kyun Ki ),정혜숙 ( Hae Suk Cheong ),서정웅 ( Jung Woong Seo ),정현아 ( Hyun Ah Chung ) 대한내과학회 2012 대한내과학회지 Vol.83 No.5
Trimethoprim-sulfamethoxazole (TMX-SMZ) is the initial treatment for Pneumocystis jiroveci pneumonia in human immunodeficiency virus (HIV) patients. About 20% of patients do not complete the TMX-SMZ treatment due to treatment failure or adverse reactions. Pentamidine isethionate has been used for P. jiroveci pneumonia as a second-line regimen. Although hypoglycemia is a common adverse effect of pentamidine, pentamidine-induced hypoglycemia has not been reported in Korea. We present an HIV patient with grand mal seizures caused by pentamidine-induced hypoglycemia who was managed successfully with IV dextrose infusion. Mental changes can occur during pentamidine treatment, but hypoglycemia is often ignored and misdiagnosed as epilepsy or stroke. It can result in seizures, coma, and even death. We should be aware of pentamidine-induced hypoglycemia, which can lead to severe neurologic deficits and diabetes mellitus. (Korean J Med 2012;83:679-682)
듀얼 빔 전단간섭계를 이용한 압연방향에 따른 기계구조용 탄소강의 면내 변위 정량적 측정에 대한 연구
강찬근(Chan-Geun Kang),김상채(Sang Chae Kim),김한섭(Han-Sub Kim),이항서(Hang-Seo Lee),정현일(Hyun-il Jung),정현철(Hyun-Chul Jung),송재근(Jae-Geun Song),김경석(Kyeong-suk Kim) 한국기계가공학회 2021 한국기계가공학회지 Vol.20 No.4
In this paper, an in-plane deformation measuring system using a dual-beam shear interferometer was constructed to measure the in-plane deformation of the measuring object. The in-plane deformation of the object was quantitatively measured according to the load and surface treatment conditions of the object. We also verified the reliability of the proposed technique by simultaneously performing the technique with an electronic speckle pattern interferometry system (ESPI), which is another laser application measurement technology. Digital shearography directly measures the deformation gradient or strain components and has the advantages of being full-field, noncontact, highly sensitive, and robust. It offers a much higher measurement sensitivity compared with noncoherent measurement methods and is more robust and applicable to in-field tests.
황용 ( Yong Hwang ),이상헌 ( Sang Heon Lee ),홍성철 ( Sung Chul Hong ),김도영 ( Do Young Kim ),김용진 ( Yong Jin Kim ),서정웅 ( Jung Woong Seo ),손인성 ( In Sung Son ),정현아 ( Hyun A Jung ),최홍석 ( Hong Seok Choi ),이정화 ( Jun 대한류마티스학회 2012 대한류마티스학회지 Vol.19 No.4
Giant cell arteritis (GCA), the most common form of systemic vasculitis in adults, preferentially involves large and medium-sized arteries in patients over the age of 50. The classic manifestations are headaches, jaw claudication, polymyalgia rheumatica, and visual symptoms. Acute myeloid leukemia (AML) is a hematopoietic stem cell disorder characterized by a block in the differentiation of hematopoiesis, resulting in the growth of a clonal population of neoplastic cells or blasts. This malignant alteration in hematopoietic stem cells leads to a loss of normal hematopoietic function, which, if left untreated, typically leads to death within weeks to months of its clinical presentation. Although there have been reports of CLL or CML accompanied by several kinds of autoimmune vascular diseases, such as polymyalgia rheumatica, GCA, or necrotizing temporal arteritis, no studies have reported a case of AML with GCA. We experienced an 80-year-old male patient who developed AML 6 years after the diagnosis of GCA. He was under the use of oral glucocorticoid, hydroxychloroquine, and methotrexate at the time of the diagnosis of the AML. This is the first case in Korea to report GCA accompanied by AML.