http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Clomiphene Citrate와 FSH 또는 Clomiphene Citrate와 hMG의 연속병합에 의한 배란유도주기에서 인공수정 후 임신율의 비교
정구성,홍기언,유승환,이현숙,이종인,허영문,전은숙,윤정임,홍정의,이지삼,Jung, Goo-Sung,Hong, Ki-Eon,You, Seung-Hwan,Lee, Hyeon-Sook,Lee, Jong-In,Hur, Young-Mun,Jeon, Eun-Suk,Yoon, Jeong-Im,Hong, Jeong-Eui,Lee, Ji-Sam 대한생식의학회 1999 Clinical and Experimental Reproductive Medicine Vol.26 No.3
Objective: To evaluate the effectiveness of CC+FSH or CC+hMG in intrauterine insemination (IUI) cycles for the treatment of infertility. Method: Patients received daily 100 mg of clomiphene citrate (CC) for 5 days followed by hMG or FSH. A single IUI was performed at 36 h after hCG. Clinical pregnancy was classified if a gestational sac or fetal cardiac activity was seen on ultrasound. Results: The overall clinical pregnancy rate was 19.1% per cycle (17/89) and 21.5% per patient (17/79). More clinical pregnancies were recorded in CC+FSH (23.1%, 6/26) than CC+ hMG cycles (17.5%, 11/63), but this difference was not statistically significant. No differences were found in age, duration of infertility, follicle size, levels of estradiol ($E_2$) on the day of hCG injection and total motile sperm counts between pregnant and non-pregnant groups. However, more ampules of gonadotropins were used in pregnant group than non-pregnant group (p<0.05). Conclusion: Combination of CC and hMG may economically be more effective to induce ovulation for IUI compared to CC and FSH.
정구성,배석현,도영수,이형남,이상준 대한영상의학회 2021 대한영상의학회지 Vol.82 No.3
Cervicovaginal venous malformations are extremely rare. Sclerotherapy is proven to be effective for superficial venous malformations but not for venous malformations in the lower genital tract of female. A 52-year-old female presented with intermittent vaginal bleeding. The amount of vaginal bleeding gradually increased over 3 months. Contrast-enhanced pelvis CT showed several phleboliths and dilated vessels, but pelvic angiography showed no early draining veins, nidus, or feeding artery. We performed transvaginal direct puncture and ethanol sclerotherapy rather than surgical treatment because she wanted to preserve the uterus. After four sessions of sclerotherapy, she had significantly decreased vaginal bleeding without complications. Here, we report the first case of cervicovaginal venous malformations successfully treated with transvaginal direct puncture and ethanol sclerotherapy.
정구성,서정욱,배석현,신원선 대한영상의학회 2019 대한영상의학회지 Vol.80 No.3
Transcatheter arterial chemoembolization (TACE) improves the survival rate in patients with hepatocellular carcinoma (HCC). Despite the low probability, iatrogenic hepatic arterial dissections during interventional procedure are rarely created by the technical difficulties. Direct trauma from the guidewire, the tip of the catheter, or the jet of contrast injection can contribute to iatrogenic hepatic arterial dissections. We report one case of a female who had HCC necrosis caused by iatrogenic hepatic arterial dissection during TACE. Ischemia resulting from iatrogenic hepatic arterial dissection during TACE was smilar to the result of transarterial embolization for HCC on our case. To our knowledge, none of the similar cases was reported in previously published literatures.
정구성,이옥란 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.1
일록춘폐흡충의 조항원 중 항원단백질의 항원성 차이를 보고자 이 연구를 시도 하였다. 충체 추출물 조항원을 Sephacryl S-300 gel filtration과 DEAE anion exchange chromatography에 의해 각각 조항원을 분리하였다. 이들 분리된 항원은 SDS-PAGE로 단백질 분획상을 구별 하였고, 효소면역 반응(ELISA)에 의하여 항원성을 비교하였다. Gel filtration으로 분리된 S2항원과 chromatography로 분리된 D4 및 D5 항원이 각각의 분리항원중에서 강한 항원성을 나타내었다. 이들은 항원성이 보다 낮은 다른 분리항원에 비해 분자량 8∼9 kDa, 27∼29 kDa, 37∼39 kDa, 50 kDa, 55 kDa 및 60 kDa 분획의 염색강도가 높았고, 이 중 8∼9 kDa를 제외한 나머지 분획들은 immunoblot으로 강한 항원성이 증명 되었다. This study was done to detect the antigenic component from the crude worm extract of Paragonimus iloktsuenensis. Three and five protein fractions, S1∼S3 and D1∼D5 were separated by Sephacryl S-300 gel filtration and by DEAE anion exchange chromatography, respectively form the crude antigen(whole worm extract: PIWA) of P. iloktsuenensis. These fractions were further analyzed by SDS-PAGE(SDS-polyacrylamide gel electrophoresis). The antigenicities of those protein fractions were evaluated by OD (optical density) value of ELISA(enzyme-linked immunosorbent assay), reacted with the serum of the rats infected with P. iloktsuenensis. The results were as follows: 1. The worm extracts(crude antigens) were separated in three fractions, S1, S2 and S3 by Sephacryl S-300 gel filtration. By SDS-PAGE, the characteristic fraction of S1 was 98 kDa, while those of S2 were 20 kDa, 27∼28 kDa, 38 kDa, 50 kDa, 55 kDa and 60 kDa, and of S3 were 12∼13 kDa, 17∼18 kDa and 35∼36 kDa, respectively. The major fraction was of 27∼29 kDa molecular weight among the three fractions. The worm extracts were separated in five fractions, D1, D2, D3, D4 and D5 by DEAE anion exchange chromatography. The characteristic fractions of D1 were 14∼15 kDa and 17∼18 kDa, and of D2 were 12∼13 kDa and 14∼15 kDa, and of D3 were 27∼28 kDa and 35∼36 kDa, and of D4 were 27∼28 kDa, 35∼36 kDa, 38∼39 kDa and 50 kDa, and of D5 were 8∼9 kDa, 27∼29 kDa, 37∼39 kDa, 55 kDa and 60 kDa, respectively. 2. The antigenicity of the fractions, expressed by the intensity of OD value of ELISA. The S2, D4 and D5 revealed stronger antigenicity than those of others. Statistically, antigenicity of S2 antigen (0.98±0.36∼1.42±0.55) was stronger(p<0.001) than that of S3(0.41±0.11∼0.90±0.41) of most low OD values in separated antigens by gel filtration, and D5 antigen (0.73±0.22∼1.38±0.65) of highest OD value was stronger(p<0.001) in all infection. That of D2(0.37±0.13∼0.51±0.23) of lowest OD values in separated antigens by chromatography. D1 showed relatively strong antigenicity compared with the other in periods of two and four weeks after infection. Among separated antigens, the 27∼29 kDa and 37∼39 kDa of protein components fractioned from whole worm extract crude antigen of P. iloktsuenensis plays a important role of humoral immune reaction in this parasitic infection, and the protein of 17∼18 kDa was regarded as sensitive antigen at early period.
고혈압성 질환을 동반한 임산부에서 hydralazin의 혈액동력학적 변화에 대한 연구
정구성(KS Jung),정기호(KH Jung),이권해(KH Lee),조태호(TH Cho) 대한산부인과학회 1988 Obstetrics & Gynecology Science Vol.31 No.8
1985년 6월1일부터 1986년 9월30일까지 만 1년 9개월간 순천향대학병원 산부인과에 입원한 산모중, 임신말기에 고혈압을 동반한 20명의 산모를 순수한 전자간증군과 만성고혈압을 가 진 산모군으로 나누어, hydralazine혈관투여후 나타나는 혈액동력학적 변화를 M-형 초음파 심장촬영술을 이용하여 다음과 같은 결론은 얻었다. 1. 전자간증군은 만성고혈압산모군에 비해 hydralazine투여전의 심장지수는 낮고 전신혈관저 항은 높게 나타났다. 2. hydralazine투여후 전자간증군의 평균동맥압과 전신혈관저항은 각각 18%와 34%의 감소를 나타냈다. 3. hydralazine 투여후, 전자간증군에서 맥박수와 심장지수는 각각 18%와 24%의 증가를 나 타났다. 4. 만성고혈압군에서는 평균동맥압과 전신혈관저항이 각각 11% 와 19%의 감소를 나타났다. 5. 두군 전체의 hydralazine투여전, 평균동맥압과 투여후 퍼센트변화 사이에는 상관관계가 없 었다. 6. hydralazine 투여전 , 심장지수에 대한 투여후 퍼센투변화 사이에는 역상관관계를 나타났 다. 7. hydralazine 투여전, 전신혈관저항과 투여후, 퍼센트변화 사이에는 역상관관계를 나타냈다. 8. hydralazine 투여후, 평균동맥압의 퍼센트 변화와 전신혈관저항의 퍼센트변화 사이에는 높 은 상관관계를 나타냈다. The hemodynamic changes after intravenous administraion of hydralazine were assessed using M-mode echocardiography in 20 pregnancy patients with severe hypertension, who were divided into two group ; preeclampsia (group 1) and essntial hypertension and/or superimposed preeclampsia (group 2) during period from Jane, 1, 1985 to September 30, 1986. The following results were obtained; 1. group 1 had significantly lower pretreatment cardiac index (p<0.02) and higher systemic vascular resistance (p<0.05) than group 2. 2. After hydralazine injecion, a significantly decrease in mean arterial pressure (18%) an systemic vascular resistance (34%) in group 1 (p<0.001 for both). 3. A significantly increase in heart rate (18%) and cardiac index (24%) in group 2 (p<0.001 for both). 4. In group 2 the mean arteial pressure and systemic vascular resistance fell by an average of 11% and 19% (p<0.02, p<0.01) 5. Correlation was not found between the initial values of mean blood pressure and the post-hydralazine percent changes for total patients population (r=0.205, p>0.2). 6. Inversed correlation was found , between the initial values of cardiac index and the past-hydralazine percent charges(r=-0.62, p<0.01). 7. Inversed correlation was found between the post-hydralazine percent changes and the control value of vascular resistance (r=-0.48, p<0.05). 8. After injection a significantly correlation was found between the percent changes of mean arterial pressure and the percent changes of systemic vascular resistance (r=0.74, p<0.001).