개불의 메탄올 추출물에서 Sterol의 구조 확인

장성근,채석,정효석,박영현,Chang, Sung Keun,Chai, Seok,Jeong, Hyo Seok,Park, Young Hyun 대한화학회 1997 대한화학회지 Vol.41 No.8

R&D투자, 기술경영능력, 기업성과간의 관계

장성근,신영수 한국경영학회 2008 한국경영학회 통합학술발표논문집 Vol.2008 No.8

산학협동의 필요성에 관한 소고

장성근,권혁태 順天鄕大學校 學生生活硏究所 1996 學生生活硏究 Vol.3 No.-

Recently, industry-university cooperation has become a popular topic in Korea, which has been proved as one of essential for the industrialization in advanced countries. However, the main leaders of technical innovation, universities, institutions, and enterprises have mostly been doing their researches independently rather than relying on the co-research for the technical innovation. Considering the current situations, Korean goverment should set up the policy that those leader of technical innovations be reorganized in systematical an institutional sense, which end up with the co-research for the technical innovation.. Otherwise, Korea can't jump into the industrially advanced nation in which most of economic problem, especially, the problem of international payment can be solved through the relative advantage of technology. Furthermore, there exist an unlimited competition in high technology and a severe protectionism of technology among countries after the appearance of WTO. In establishing the system of industry-university cooperation, government takes into account the facts that industry should be organized into export oriented structure and be restructured to maximization of autonomy and originality of enterprise, and that the collection of information of technology and science, deregulation, and tax benefit and financial support should be executed by government. Also, industry-university cooperation brings about the better results through the introduction of part-time work at company for the university student, which finally cultivate the high technology man power.

흰쥐 연골 육종세포에서 transglutaminase의 정제 및 특성에 관한 연구

장성근 순천향대학교 1987 논문집 Vol.10 No.3

Following proteolytic dissociation of rat chondrosarcoma cells, the activity of Ca-depedent purtrescine incorporation into various proteins increased several fold in the cell-lyzate. Addition of proteases into serum free medium contanining cycloheximide during the culture of chondrosarcoma cells, also stimulated the similar enzyme activity. The chromatographic properties of the enzyme activity on DEAE-cellulose, Sephacryl S-300, and hydroxyappatite differed from those of previously characterized transglutaminases. Following a series of enzyme digestion of putrescine labeled casein and separation of digest on a polyamine analyzer, the labeled amino acid was identified as γ-glutamylputrescine. From gel-permeation studies, the molecular weight of the chondrosarcoma cell transglutaminase was estimate to be 100,000. Casein and fibrin were substrates but not fibronectin, proteoglycan, and collagens. In fibrin polymerization, α-polymer and γ-γdimer formed simultaneously. Thrombin stimulated the partially purified chondrosarcoma cell transglutaminase 2-e fold with a substantial decrease of its molecular weight. Similar transglutaminase activity was identified in rat liver and muscle particulate fractions. These findings suggest the cellular transgluta-minase which is modulated in cells is distinct from previously characterized transglutaminases and that its enzyme activity may be regulated by intrinsic proteases.

자근으로부터 혈소판에 작용하는 천연색소물질에 관한 연구

장성근,박영현 한국식품위생안전성학회 2000 한국식품위생안전성학회지 Vol.15 No.2

Lithospermum erythrorhyzon has been used as a red fooddye and traditional Chinese medicine to treat wounds, skin diseases and burns. Platelet activation plays an important role in thrombosis and haemostasis. Here, we studied the inhibition of platelet activation and its active compound from the root of Lithospermum erythrorhyzon. Its ethyl acetate extract inhibited the aggregation of washed rabbit platelets induced by collagen or thrombin. Five naphthoquinone pigments, shikonin, acetylshikonin, isobutylshikonin, α-methyl-n-butylshikonin and (β,β-dimethylacrylshikonin were isolated by means of high pressure liquid chromatography. The structures were determined by comparison of their proton nuclear magnetic resonance spectra. The potency of their inhibition was in the following order : β,β-dimethylacrylshikonin≥α-methyl-n-butylshikonin$gt;isobutylshikonin$gt;acetylshikonin$gt;shikonin. It is suggested that the size of the aliphatic hydroxy group of shikonin is important for the enhancement of potency.

大邱地域 中小纖維業體에 대한 從業員의 認識과 移職에 관한 考察

蔣成根 慶北大學校 經營大學院 1995 最高經營者課程 論文集 Vol.- No.22

Structure and Electrical Properties of BiFeO3 Thin Films Fabricated using Chemical Solution Deposition and Annealed in Air, N2 and O2 Atmospheres

장성근,김윤장 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.65 No.7

We prepared BiFeO3 (BFO) thin films on Pt(111)/Ti/SiO2/Si(100) substrates by using a chemicalsolution deposition method and then annealed in Air, N2 and O2 atmospheres. Improved electricalproperties were observed in the BFO thin film annealed in a N2 atmosphere. The leakage currentdensity of the BFO thin film annealed in a N2 atmosphere 3.2 × 10−7 A/cm2 at 100 kV/cm wasthree orders of the magnitude lower than that of the BFO thin film annealed in an O2 atmosphere. The remnant polarization (2Pr) and the coercive electric field (2Ec) values of the BFO thin filmannealed in a N2 atmosphere were 28 C/cm2 and 672 kV/cm at a maximum electric field of 640kV/cm with a frequency of 10 kHz. Also, we confirmed that the 2Pr was fairly saturated at ameasurement frequency of about 20 kHz for the BFO thin film annealed in a N2 atmosphere.

Eu와 V 동시 도핑에 의한 BiFeO3 박막의 구조와 전기적 특성

장성근,김윤장 한국전기전자재료학회 2019 전기전자재료학회논문지 Vol.32 No.3

Pure BiFeO3 (BFO) and (Eu, V) co-doped Bi0.9Eu0.1Fe0.975V0.025O3+δ (BEFVO) thin films were deposited on Pt(111)/Ti/SiO2/Si(100) substrates by chemical solution deposition. The effects of co-doping were observed by X-ray diffraction, Raman spectroscopy, and scanning electron microscopy (SEM). The electrical properties of the BEFVO thin film were improved as compared to those of the pure BFO thin film. The remnant polarization (2Pr) of the BEFVO thinfilm was approximately 26 μC/cm2 at a maximum electric field of 1,190 kV/cm with a frequency of 1 kHz. The leakage current density of the co-doped BEFVO thin film (4.81×10–5 A/cm2 at 100 kV/cm) was two orders of magnitude lower than of that of the pure BFO thin film. Pt (111) / Ti / SiO2 / Si (100) 기판 상에 순수 BiFeO3 (BFO) 및 유로퓸을 동시 도핑한 Bi0.9Eu 0.1Fe0.975V0.025O3 + δ(BEFVO) 박막을 화학 물질 용액 증착법으로 형성하였다. X 선 회절, 라만 분광법 및 주사 전자 현미경을 사용하여 동시 도핑의 영향을 관찰하였다. 순수한 BFO 박막과 비교하여 BEFVO 박막의 전기적 특성이 향상됨을 확인했습니다. BEFVO 박막의 잔류 분극 (2Pr)은 1 kHz의 주파수에서 1190 kV/cm의 최대 전기장에서 약 26 μC/cm2을 보였고. 동시 도핑 된 BEFVO의 누설 전류 밀도는 100 kV/cm에서 순수한 BFO 박막의 누설 전류 밀도보다 100배 낮은 4.8 x 10-5 A/cm2 을 보였다.

디자인 중심 신제품 개발 전략의 성공 요인:초콜릿 폰 개발 사례를 중심으로

장성근,류성일,김진우 한국경영과학회 2007 經營 科學 Vol.24 No.1

The function of product design has been an important part for success on new product development. We deeply studied ‘Chocolate-Phone’ case which is considered as a representative of adopting design-oriented new product development strategy. According to this study, we found three contextual factors and nine key success factors for design-oriented new product development. The contextual factors consist of the strong needs for innovative product development, customer's needs for the emotional value, competitive situation for the new product launching. The key success factors consist of design, development, marketing, overall sides. The key success factors of design side are to select talented designers and take an insight for market and communication skill. The key success factors of development side are to possess high technological abilities, to do divergence with removing or giving up some function, management's strong support. The key success factors of marketing side are to bring core marketers from outside, capacity to gather ideas from outside. The key success factors of overall side are to share design-oriented principle with other functions and to change member's mind from engineer-oriented to market-oriented.

Diethylnitrosamine 과 Diethanolnitrosamine 이 흰쥐 혈청의 탈수소 효소활성에 미치는 영향

장성근,이동욱,박기현 ( Sung Keun Chang,Dong Wook Lee,Ki Hyun Park ) 생화학분자생물학회 1991 BMB Reports Vol.24 No.6

Lactate dehydrogenase(LDH) and its isozyme patterns were investigated in the serum of the rats treated with diethylnitrosamine(DENA) or diethanolnitrosamine(DELNA). LDH activity was remarkably increased by the treatment of these chemicals, but that was gradually decreased from about 2 weeks after administration of the chemicals. Especially the relative activity of LDH isozyme 1 was increased remarkably, whereas that of isozyme. 5 was slightly decreased from the 5th days. However, the activity ratios of the isozymes were not changed significantly with time course. This unique alterations in serum LDH activity might be provide a useful information for the detection of tissue toxicity induced by these chemicals.