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해조류 메탄올 추출물의 Prolyl Endopeptidase, Tyrosinase 저해 및 항응고 활성 스크리닝
이현진,김진희,이주현,김종식,곽상태,이경복,송경식,최병욱,이봉호,Lee, Hyun-Jin,Kim, Jin-Hui,Lee, Chu-Hyun,Kim, Jong-Sik,Kwak, Sang-Tae,Lee, Kyung-Bok,Song, Kyung-Sik,Choi, Byung-Wook,Lee, Bong-Ho 한국생약학회 1999 생약학회지 Vol.30 No.3
About forty sea weeds were screened for their inhibitory effects against prolyl endopeptidase, tyrosinase and thrombus coagulation. Out of them, methanolic extract of Ecklonia cava, Sargassum patens, Sargassum hemiphyllum, Sargassum thunbergii, Sargassum singgildianum, Hizikia fusiformis, and Ishige okamurae inhibited more than 90% of prolyl endopeptidase activity at 40 ppm. Sargassum siliquastrum and Ecklonia cava exhibited 51% and 76% of inhibitory activity against tyrosinase at 40 ppm, respectively. In APTT assay system, Sargassum singgildianum, Pterocladia capilacea and Hizikia fusiformis delayed coagulation of thrombus about two times (210, 211, and 198% over control at ca 367 ppm, respectively) and in TT assay, Lomentaria catenata, Laurencia okamurae, and Hizikia fusiformis did most effectively (216,197, and 251% at ca 367 ppm, respectively).
경사지 활용 저층 집합주택의 개발가능성과 경사도별 모델 제안
이현진,양우현,Lee, Hyun-Jin,Yang, Woo-Hyun 한국주거학회 2009 한국주거학회 논문집 Vol.20 No.1
This research starts from the questioning of current housing development on the hilly site in Korea. It aims to investigate various design techniques of low-rise housing as an alternative housing plan on hilly sites. Several generic solutions of the combination of building type and road pattern are tested for a simulation process, and evaluated in terms of crucial design issues; development density, parking space and open space. As a result, four reasonable models are selected for making full use of geographical features of hilly site, two models each land slope of $18^{\circ}$ and $26^{\circ}$. Several design techniques for each model are also suggested, in ensuring the development feasibility by considering land slope, vehicular access and parking, common open space, and community facilities.
이현진,김종규,강용혁,Lee, Hyunjin,Kim, Jongkyu,Kang, YongHeack 한국교통대학교 융복합기술연구소 2012 융ㆍ복합기술연구소 논문집 Vol.2 No.1
1) 국제에너지위원회 IEA 산하 SolarPACES(Solar Thermal Power and Chemistry Energy System)는 태양열발전 및 화학 관련한 기술 개발 및 보급을 목표로 한국을 포함하여 현재 20개국이 활동 중이다. 2011년 우리나라는 집행위원회뿐만 아니라 6개 기술 분야 중에 태양열발전, 태양열화학, 태양열집광기술 및 적용 3개 분야에 참여하고 있다. 2) 2011년 기준으로 약 1.2GW 용량의 태양열 발전소가 전 세계에 설치되었고, 스페인 582MW, 미국 507MW로 대부분을 차지한다. 현재 미국 8GW, 스페인 4.46GW, 중국 2.5GW를 포함하여 전체 약 17GW 용량 발전소들이 건설 또는 계획 중에 있다. 3) 국제에너지위원회 IEA는 태양열 발전소는 태양광에 비해 약 1/3정도의 발전 용량을 갖겠지만, 열저장을 이용한 높은 가동시간을 바탕으로 2050년에는 태양광이나 바이오매스와 비슷한 수준으로 전기를 공급하여 전 세계 전기의 11.3% 정도에 이를 것으로 예측하고 있다. Concentrated Solar Power (CSP) is a renewable energy to generate electricity by using solar thermal energy as a heat source to drive turbines or engines for thermodynamic cycles. This paper introduces ongoing projects in SolarPACES(Solar Power and Chemical Energy systems) under the REWP(Renewable Energy Working Party) in the IEA(International Energy Agency). Then, the current status of international CSP markets and domestic activities is summarized. Finally, the CSP outlook by IEA and the key technological challenges to be overcome for its realization are presented.
한방치료로 관해가 유도된 소아 크론병 환자의 증례 보고
이현진,이하늘,정해인,조윤재,금창열,한아람,하나연,김진성,Lee, Hyun-Jin,Lee, Hanul,Jeong, Hae In,Cho, Yun-jae,Keum, Chang-Yul,Han, Aram,Ha, Na-yeon,Kim, Jinsung 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.5
Objectives: This case study examined the effectiveness of Korean medical treatment for pediatric Crohn's disease. Methods: A 15-year-old female Korean patient with Crohn's disease received acupuncture, electroacupuncture, herbal medicine, moxibustion, and aromatherapy treatment for 1 month in a hospital. Results: Decreases in the Pediatric Crohn's Disease Activity Index score (from 22.5 to 7.5) and the size of two abscesses (from 39.97 mm to 33.36 mm, and from 28.14 mm to 18.71 mm) according to an abdominal CT were observed following treatment. Nausea and vomiting disappeared, stool condition improved, and weight increased (from 30 kg to 33 kg) following treatment. Nausea and vomiting disappeared, stool condition improved, and weight increased (from 30 kg to 33 kg) following treatment. Conclusion: It would be worth examining the long-term effectiveness of Korean medical treatment for pediatric Crohn's disease.
양양군과 포항 해역에 시설한 인공어초에서 진행된 해조천이와 군집에 관한 연구
이현진,최창근,Lee, Hyeon Jin,Choi, Chang Geun 한국해양생명과학회 2019 한국해양생명과학회지 Vol.4 No.2
이 연구는 2016년 9월에 강원도 양양군 남애리, 경상북도 포항시 구룡포읍 석병2리에 설치한 인공어초를 대상으로 해조류 군집 변화를 관찰하기 위하여 연구를 수행하였다. 현장조사는 2017년 2월, 5월, 8월, 11월에 계절별 1회씩 SCUBA Diving으로 수행하였으며, 정량조사와 정성조사를 병행하였다. 본 연구에서 녹조류 11종, 갈조류 15종, 홍조류 68종을 포함하여 총 94종이 채집되었으며, 양양에서 66종(녹조류 8종, 갈조류 9종, 홍조류 49종), 포항에서 65종(녹조류 7종, 갈조류 9종, 홍조류 49종)이 채집 및 동정되었다. 중요도를 기반으로 판단한 우점종의 경우, 양양은 다시마(Saccharina japonica)가 우점종, 구멍갈파래(Ulva australis)가 준우점종이었으며 포항은 불레기말(Colpomenia sinuosa), 우뭇가사리(Gelidium elegans) 순으로 우점하였다. 두 해역 모두 어초 설치 초기에 각각 파래류, 불레기말이 착생한 후, 다시마, 감태, 우뭇가사리 등 다년생 해조가 생육하며 우점하여 기존의 천이 패턴과 유사하였다. 해조상 변화를 통해 군집관계를 명확히 하기 위해서는 추후 지속적인 모니터링을 통해 장기적인 변화를 관찰하여 해조군락이 안정되기까지의 천이 과정에 관한 모니터링이 필요한 것으로 판단된다. This study was carried out to observe the changes of seaweed community in artificial reefs installed in September, 2016 in Namae-ri, Yangyang-gun, and Seokbyeong-ri, Pohangsi, Korea. Field surveys were conducted by SCUBA diving once a season in February, May, August, and November of 2017, and quantitative survey and qualitative survey were carried out in parallel. In this study, a total of 94 species, including 11 green algae, 15 brown algae and 68 red algae were appeared. 66 species (8 green algae, 9 brown algae, 49 red algae) and 65 species (7 green algae, 9 brown algae, 49 red algae) were collected and identified in Yangyang and Pohang. In dominant species, Yangyang was dominant species of Saccharina japonica and subdominant species of Ulva australis. Pohang dominated in order of Colpomenia sinuosa and Gelidium elegans. In both coastal areas, Ulva spp., Colpomenia sinuosa were grown at the early stage of reforestation, and perennial seaweeds such as Saccharina japonica, Ecklonia cava and Gelidium elegans were grown. In order to clarify the clustering relation through flora change, it is necessary to monitor the transition process until the seaweed community is stabilized by observing the long-term change through continuous monitoring.
이현진,여성일,박준범,Lee, Hyunjin,Yeo, Seong-Il,Park, Jun-Beom The Korean Dental Association 2017 대한치과의사협회지 Vol.55 No.9
Purpose: The effects of various concentrations of ascorbic acid on stem cell spheroids derived from intraoral areas are not known yet. Thus, the purpose of this study is to evaluate the effects of different concentrations of ascorbic acid on the morphology and cellular viability of stem cell spheroids derived from the gingival tissues. Materials and Methods: Stem cells were plated onto silicon elastomer-based concave microwells and grown in the presence of ascorbic acid at concentrations ranging from 0.003% to 0.3%. The morphology of the cells was viewed under an inverted microscope at day 1, 2, 3 and 5. Qualitative live/dead assay and quantitative cellular viability using Cell Counting Kit-8 were performed on day 2 and day 5. Results: Gingiva-derived stem cells formed spheroids irrespective of ascorbic acid concentration in silicon elastomer-based concave microwells. Increase in the diameter of spheroid were seen with higher concentrations of ascorbic acid. Higher cellular viability was seen in higher concentrations of ascorbic acid. Conclusion: Within the experimental setting, the application of ascorbic acid on stem-cell spheroids produced an increase in the size and higher viability with higher dosage. It can be suggested ascorbic acid be applied with stem cell spheroids for tissue engineering purposes.