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소화기 ; 진행성 위암 환자에서 1차 요법으로 FOLFOX-4 병합화학 약물치료의 효과와 안정성
이천우 ( Cheon Woo Lee ),박무인 ( Moo In Park ),박선자 ( Seun Ja Park ),문원 ( Won Moon ),김형훈 ( Hyung Hun Kim ),이혜원 ( Hae Won Lee ),구기환 ( Ki Hwan Ku ),김부경 ( Bu Kyung Kim ) 대한내과학회 2012 대한내과학회지 Vol.82 No.1
This study examined the efficacy and safety of oxaliplatin-5-fluorouracil-Leucovorin (FOLFOX-4) combination chemotherapy as first-Line treatment in patients with advanced gastric cancer. This retrospective study enrolled 35 patients diagnosed with pathologically proven surgically unresectable gastric cancer who received FOLFOX-4 combination chemotherapy between August 2006 and February 2009, using medical records. The administered dose of oxaliplatin was 85 mg/㎡ for 2 hrs and Leucovorin 200 mg/㎡ for 2 hrs on day 1, 5-fluorouracil 400 mg/㎡ as a bolus and 5-fluorouracil 600 mg/㎡ for 22 hrs on days 1 and 2, every 2 weeks. The response was assessed every three cycles. Toxicity was evaluated for every course of chemotherapy according to the NCI toxicity criteria ver. 2.0. The median patient age was 61 (range 27-77) years. The median overall survival was 8.50 (6.23-10.90) months and the median time to progression was 4.50 (0.38-9.75) months. With FOLFOX-4, there was no complete remission and 19 partial responses, for a response rate of 54.3%. Over 298 cycles, anemia worse than NCI toxicity grade 3 occurred in 1.3%, Leukopenia in 1.6%, neutropenia in 9%, and thrombocytopenia in 3.2%. Grade 1-2 neuropathy occurred in 14.7% of the cycles. Neutropenic fever occurred in two cycles and the regimen was changed because of side effects in one FOLFOX-4 has a very high response rate with mild toxicity in patients with advanced gastric cancer as a first-Line treatment. (Korean J Med 2012;82:37-44)
이천우 ( Cheon Woo Lee ),박무인 ( Moo In Park ),박선자 ( Seun Ja Park ),문원 ( Won Moon ),김형훈 ( Hyung Hun Kim ),김봉준 ( Bong Joon Kim ),심인경 ( In Kyoung Shim ),박시성 ( Si Sung Park ) 대한소화기학회 2011 대한소화기학회지 Vol.58 No.5
Superior mesenteric artery (SMA) syndrome is a rare disorder, characterized by compression of the third segment of the duodenum by the mesenteric artery at the level of the SMA, resulting in duodenal dilatation. Precipitating factors of the SMA syndrome include prolonged bed rest, weight loss, abdominal surgery, and increased lordosis of the spine. We report a case of SMA syndrome caused by anorexia nervosa in a 15-year-old adolescent girl. CT and an upper gastrointestinal contrast series revealed partial obstruction of the third portion of duodenum and decreased aortomesenteric distance. The patient`s symptoms were successfully treated with total parental nutrition and psychiatric treatment including supportive, cognitive behavioral therapy and antidepressant medication. This case shows that SMA syndrome is an unusual gastrointestinal complication that may occur in patients with anorexia nervosa. (Korean J Gastroenterol 2011;58:280-283)
중국 부동산 시장의 개혁 과정과 향후 과제에 대한 고찰
차숙로(Che Shulu),이천우(Cheon-Woo Lee),이미숙(Misuk Lee) 한국혁신학회 2021 한국혁신학회지 Vol.16 No.1
중국 부동산 시장은 경제와 밀접하게 관련되어 있으며, 중국경제를 이해하기 위해서는 중국의 부동산 시장을 이해하는 것이 매우 중요하다고 할 수 있다. 그러나 지금까지 중국 통계자료 획득의 어려움 등으로 인해 중국 부동산 가격의 결정요인이나 부동산 정책과 관련된 국내 연구는 그리 활발히 수행되지 못한 것으로 판단된다. 본 연구에서는 중국 부동산 시장의 개혁 과정을 시간적 흐름에 따라 살펴보고, 중국 정부의 주요 부동산 정책을 단계별로 구분하여 정리하는 것을 목적으로 하였다. 연구 결과, 1978년 개혁⋅개방 이후에 나타난 중국 부동산 시장의 변화는 초기 시장 형성 단계, 국부 과열 단계, 시장 조정 단계, 시장 활성화 단계, 거시 조정 단계, 경제위기 이후 시장 조정 단계, 새로운 성장점 추구 단계의 7단계로 정의할 수 있었다. 본 연구는 단계별 부동산 정책의 주요 특징과 정책 도입 당시의 배경을 심도 있게 논의했다는 점에서 의미가 있으며, 중국 경제 현황에 대한 유용한 정보를 제공할 수 있을 것으로 기대된다. Since the Chinese real estate market is closely related to the economy, it is very important to understand the Chinese real estate market in order to understand the Chinese economy. However, domestic studies related to real estate policies and determinants of real estate prices in China have not been actively conducted due to difficulties in obtaining statistical data and researches from China. The purpose of this study is to examine the reform process of the Chinese real estate market over time, and to organize the major real estate policies of the Chinese government in stages. According to the result, the changes in the Chinese real estate market that appeared after the reform and opening in 1978 can de divided into seven stages: the initial market formation stage, the local overheating stage, the market adjustment stage, the market activation stage, the macro-control stage, the market adjustment stage after the economic crisis, and the new growth point stage. This study is meaningful in that it discusses in-depth the main characteristics of real estate policies at each stage, and is expected to provide useful information on the current state of the Chinese economy.