이화여자대학교 학생들의 의료실태에 관한 조사 연구

이종숙,Lee, Jong-Sook 대한예방의학회 1982 Journal of Preventive Medicine and Public Health Vol.15 No.1

A study was carried out in order to obtain the status of student sickness and medical care in University Health Service, Ewha Womans University. This study was based on the clinical records of University Health Service and hospitals 'for student insurance pay claims during the year of 1981. And the findings from the study were as follows; 1. A total number of student patients cared at University Health Service in 1981 was 9,822 and the incidence rate of primary cared was 773 per 1,000 students. 2. A total number of student patients cared at hospitals was 393 and the incidence rate of secondary cared was 31 per 1,000 students and 5 student out of 31 per 1000 was cared under the haspitalization. 3. The evacuation rate of student patients from University Health Service to hospital was 393 out of 9,822 student primary cared or 4.0 percent. 4. The order of 5 major diseases of primary cared in University Health Service was respiratory system diseases (36.6%), Digestive system diseases (17.4%), Skin and subcutaneous tissue diseases (16.0%), Symptoms and undetermined diagnosis (13.7%) and Nerve and sensory organ diseases (12.0%) respectively. 5. The disease order of student patients(333) cared in hospitals as out-patients was Skin and subcutaneous tissue diseases (40.3%), Nervous and Sensory organ disease (19.2%), Digestive system diseases (10.8%) respectively. 6. The disease order of student patients (60) cared in hospitals as in-patients was Digestive system diseases (35.0%), Respiratory system diseases (13.3%), Nerve and sensory organ diseases (10.0%), Infectious and parasitic diseases (10.0%), and Symptom and Undetermined diagonsis (10.0%) respectively. 7. The evacuation rate of student patients in University Health Service to hospital was varied according to disease groups; the lowest rate was the diseases evacuated to Internal Medicine Department 1.5% or 75 out of 5,072 patient primary cared and the highest rate was Neuropsychiatry department 63.7% or 7 out of 11 patients. 8. The monthly distribution of student patients in University Health Service was the highest in September (17.9%) and April (15.5%) each semester. 9. The monthly number of student patients treated in hospitals was the range 20 to 40 in out patients and 2 to 9 in in-patients. 10. The hospital ill days per case were $4.3{\pm}5.0$ days in out-patients and $9.7{\pm}9.5$ days in in-patients.

비타민나무열매가루 첨가 식빵의 품질 특성 및 항산화 활성

이종숙,김정미,Lee, Jong Suk,Kim, Jung Mi 한국식품영양학회 2020 韓國食品營養學會誌 Vol.33 No.5

The purpose of this study was to prepare bread added with sea buckthorn (Hippophae rhamnoides L.) berry powder (SBBP) (1, 3, and 5%) using a straight dough method. The quality and antioxidant characteristics of the bread were analyzed. The results indicated that the pH value and dough raising power of the dough decreased and the moisture content of the bread added with SBBP increased compared to that without the SBBP. The crust color of the bread did not change significantly. However, the crumb lightness value decreased and the redness and yellowness value increased respectively to the concentration of the SBBP. The texture measurement indicated that the hardness, gumminess, and chewiness of the bread increased with the addition of the SBBP. The total polyphenol content of the bread supplemented with the SBBP was increased (4.60~16.14 mg GAE/g) compare to the control (1.67 mg GAE/g). Dose-dependent, significant-high DPPH (26.86%) and ABTS (42.52%) radical scavenging activities were observed in the bread with the addition of the SBBP up to 5%. Based on these results, the optimum amount of the SBBP to add for baking bread would be 3% and the SBBP could be considered a functional agent.

퀴노아를 첨가한 청국장의 발효기간에 따른 품질 변화

이종숙,이미희,김정미,Lee, Jong Suk,Lee, Mi Hee,Kim, Jung Mi 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.1

In this study, the quality characteristics of cheonggukjang with addition of different quinoa were investigated. We evaluated the quality and sensory characteristics of cheonggukjang, including the pH, amino nitrogen, slime contents, color value, and total aerobic bacteria. Moreover, The anti-oxidant activities were measured as total polyphenol content, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, and superoxide dismutase (SOD) activity. The pH and amino nitrogen content were noted to significantly increase during the fermentation period in all the samples. The slime content of cheonggukjang added with quinoa increased with increased fermentation time, but cheonggukjang with addition of 20% of quinoa was decreased. The L value and b value decreased significantly with increased fermentation time, but the a value increased significantly. The microbial tests of cheonggukjang with addition of quinoa showed that the aerobic micro-organisms count was 7.45~9.10 Log cfu/g. Total polyphenol contents increased in all groups during the fermentation period, and activity increased with an increased percentage of added quinoa. The DPPH radical scavenging activity and SOD-like activity of cheonggukjang (with addition of quinoa) were also significantly higher than those of the control. The sensory quality of quinoa 10% cheonggukjang was stronger in flavor, and taste, and demonstrated a higher level of overall acceptability, when compared to the other groups.

고추의 소포자 배양 시 모식물의 생육조건, 소포자 나출 방법, 치상배지 및 광배양이 배의 발생에 미치는 영향

이종숙,박은준,김문자,Lee, Jong-Suk,Park, Eun-Joon,Kim, Moon-Za 한국식물생명공학회 2007 식물생명공학회지 Vol.34 No.4

효율적이며 반복성 있는 고추의 소포자배양 시스템을 확립하기 위해 꽃봉오리로부터 소포자의 수확 시 나출 방법이 소포자 활력에 미치는 영향을 조사하는 동시에 모 식물 생육 시의 광도, 치상배지의 조성, 및 배양 광 조건이 배의 발생 및 발달에 미치는 영향을 조사하였다. 광도가 10,000 lux 와 5,500 lux로 각기 다른 곳에서 모식물이 생육된 경우 활력 있는 소포자의 비율은 큰 차이가 없었으며, 소포자 배의 발생이나 발달은 저광도인 5,500 lux에서 생육된 경우에 다소 높아 모 식물 생육 시의 광도가 소포자배의 발생에 미치는 영향이 크지 않은 것으로 나타났다. 그러나 5,500 lux에서 생육된 식물에서는 꽃봉오리의 수가 적어 배양에 필요한 소포자를 준비하기가 매우 어려웠다. 활력 있는 소포자의 비율은 체나 막자사발을 이용한 maceration 방법에 비해 blender를 이용하는 경우 13배 이상 높았다. 배의 발생 및 발달에 가장 좋았던 배지는 사용한 배지 중 MN배지였으며, 배양 광 조건은 암 상태에서 배양한 4주 후에 다시 광 상태로 옮겨 1주 배양하는 것이었다. 이상에서와 같은 결과들은 고추에서 형질전환이나 돌연변이 연구에 이용될 수 있을 정도로 많은 배를 생산할 수 있는 소포자 배양 시스템을 확립하는데 중요한 기초 자료가 될 것이다. To establish an efficient and reliable microspore culture system for pepper (Capsicum annuum L.), the effect of light intensity used for donor plant's growth, microspore isolation methods, the composition of culture medium, and culture period in light on the production of embryos were investigated. The viability of microspores taken from the plants grown under the light intensity of 10,000 lux was almost same as that from the lower (5,500 lux) light intensity, and the embryo induction and development were a bit higher when donor plants were grown under the lower light intensity. This result implies that lower light intensity does not interfere with the embryo induction and development. However, it was very difficult to prepare microspores for culture since only a small number of flower buds could be harvested from plants grown under the light intensity of 5,500 lux. Microspore isolation methods greatly affected microspores viability; that is, when microspores were isolated by blending rather than maceration, the greater number of viable microspores were easily generated (about 13 times). Among media used for microspores culture in this study, MN medium was most efficient for embryo induction and development. Total number of embryos and the number of cotyledonary embryos were highest when microspores were cultured in dark for 4 weeks, and then in light for one week. These results will be provide valuable information to set up efficient microspore culture system of hot pepper with a high frequency of embryo production, which are applicable to gene transformation and mutagenesis.

Grifola frondosa (Maitake Mushroom) Water Extract Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis Through Inhibition of Reactive Oxygen Species and Extracellular Signal-Regulated Kinase Phosphorylation

이종숙,Byung Chul Park,Yu Jin Ko,Mi Kyoung Choi,최한곤,Chul Soon Yong,Jae-Sung Lee,김정애 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.4

Grifola frondosa, a large edible mushroom also known as maitake, has been used as a health food for centuries in China and Japan. In the present study, we examined anti-angiogenic activity of a water extract of the fruiting body of G. frondosa (GFW). An in vivo angiogenesis assay using chick chorioallantoic membrane revealed that GFW (1–100 μg/mL) dose-dependently inhibited vascular endothelial growth factor (VEGF)-induced angiogenesis. In addition, GFW inhibited VEGF-induced proliferation, chemotactic migration, and capillary-like tube formation of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner. Upon stimulation by VEGF, HUVECs rapidly increased reactive oxygen species production, which was significantly blocked by the treatment with GFW. Moreover, phosphorylation of extracellular signal-regulated kinase 1/2, a downstream signaling molecule following VEGF receptor activation, was also inhibited by GFW. The results indicate that GFW effectively inhibit angiogenesis by blocking VEGF signaling and suggest that G. frondosa fruiting body may be a valuable medicinal food for treatment of angiogenesis-associated human diseases.

HS-SPME-GC/MS에 의한 혈액중 17종 유기인계 농약의 동시분석법

이종숙,정진미,이한선,염혜선,이상기,박유신,정희선,Rhee, Jong-Sook,Jung, Jin-Mi,Lee, Han-Sun,Yeom, Hye-Sun,Lee, Sang-Ki,Park, Yoo-Sin,Chung, Hee-Sun 대한약학회 2010 약학회지 Vol.54 No.6

HS-SPME-GC/MS was studied and optimized for the determination of 17 orgarnophosphorous pesiticides (OPPs: chlorpyrifos, chlorpyrifos-methyl, demeton-s-methyl, diazinon, dimethoate, EPN, fenitrothion, fenthion, malathion, methidathion, monocrotophos, parathion, phenthoate, phosphamidon, sulfotep, terbufos, triazophos) in blood. Optimum SPME parameters were selected: choice of SPME fiber (85 ${\mu}m$ polyacrylate), pH effect (0.5 N HCl), salt effect ($Na_2SO_4$, 0.2 g; 20%), headspace incubation temperature ($80^{\circ}C$), headspace incubation time (1 min), headspace adsorption time (30 min) and GC desorption time (2 min). These parameters were optimized using HS-SPME autosampler coupled with gas chromatography-mass spectrometry (GC-MS). Method validation was carried out in terms of linearity, limit of detection (LOD), limit of quantitation (LOQ) and recovery in blood. The assay was linear over 0.5~5.0 mg/l ($r^2$=0.955~1.000). Limit of detection (LOD) and limit of quantitation (LOQ) in blood were determined 0.03~0.3 mg/l (S/N=3) and 0.1~1.1 mg/l (S/N=10), respectively. Relative recovery with 0.5, 1 and 5 mg/l (in blood) were 90.8%, 98.5% and 94.1%, respectively. This method will be applied to the determination of the orgarnophosphorous pesticides in postmortem blood. The proposed protocol can be an attractive alternative to be used in routine toxicological analysis.

Quality of Coverage Analysis on Distributed Stochastic Steady-State Simulations

이종숙,박형우,정해덕,Lee, Jong-Suk-R.,Park, Hyoung-Woo,Jeong, Hae-Duck-J. Korea Information Processing Society 2002 정보처리학회논문지 A Vol.9 No.4

본 논문에서는 분산 시뮬레이션 기법 중에 하나인 MRIP(Multiple Replications In Parallel) 시나리오에서 각종 순차적인 시뮬레이션 분석 방법들의 성능을 측정할 수 있는 포함범위(Coverage)에 대한 신뢰구간(confidence intervals) 및 속도향상(Speedup)에 대해 살펴보았다. F-분포를 기반으로 한 신뢰구간에 대한 추정기(estimator)를 단일 프로세서와 다중 프로세서 상에서 참조모델(reference model)로 $M/M/1/{\infty},\;M/D/I/{\infty}과\;M/H_{2}/1/{\infty}$큐잉 시스템을 활용하여 정상상태(steady-state)에서의 평균치를 추정하는 시뮬레이션에 적용하였다. 순차적인 포함범위 분석을 위해서는 수많은 시뮬레이션 실행(Run)들이 요구되는데, MRIP 분산 시뮬레이션 시나리오에서 다중 프로세서를 이용하여 시뮬레이션을 수행하여 최종 시뮬레이션 결과를 얻는데 걸리는 신간을 감소시켰다. 또한, LNA으로 연결된 분산 컴퓨팅 시스템에 시뮬레이션을 동시에 수행시킴으로써 쉽게 필요한 수의 시뮬레이션 실행결과(Run)를 수집할 수 있다. 이는 샘플의 수가 증가됨으로써 좀더 신뢰도가 높은 최종 신뢰구간을 시뮬레이션 수행자가 얻을 수 있게 해준다. In this paper we study the qualify of sequential coverage analysis under a scenario of distributed stochastic simulation known as MRIP(Multiple Replications In Parallel) in terms of the confidence intervals of coverage and the speedup. The estimator based in the F-distribution was applied to the sequential coverage analysis of steady-state means. in simulations of the $M/M/1/{\infty},\;M/D/I/{\infty}\;and\;M/H_{2}/1/{\infty}$ queueing systems on a single processor and multiple processors. By using multiple processors under the MRIP scenario, the time for collecting many replications needed in sequential coverage analysis is reduced. One can also easily collect more replications by executing it in distributed computers or clusters linked by a local area network.

실내디자인에 나타난 유기적 형태 디자인의 표현특성 유형에 관한 연구 -2000년대 이후 인테리어디자인 잡지에 게재된 작품을 중심으로-

이종숙,박현옥,이한나,Lee, Jong-Sook,Park, Hyun-Ok,Lee, Han-Na 한국디지털건축·인테리어학회 2005 한국디지털건축인테리어학회 논문집 Vol.5 No.1

To begin with, this research arranged this concepts by analyzing paper a reference paper. So, the theory was arranged by approaching the ideal, formative and contemporary side. In order to type characteristics expression of organic design, after year 2000 printed in "Interiors" journal analyzed the contents based on interior works. 1. A type of metaphorical expression, order and the imitations of animals and plants. 2. A type of non liner, and dynamical balance and irregularity. 3. A type of mass of indeterminate form. 4. A type of fluidity by a curved line and a curved surface.

ISDN 신뢰도 및 가용도 목표치 분석

이종숙,정철오,고재상,Lee, Jong-Suk,Jeong, Cheol-O,Go, Jae-Sang 한국전자통신연구원 1992 전자통신동향분석 Vol.7 No.4

본 고에서는 Bellcore 에서 제시한 ISDN 의 신뢰도 및 가용도를 BRA(Basic Rate Access) 와 PRA(Primary Rate Access) 각각에 대해서 살펴보았다 또한 표준의사접속 (HRC : Hypothetical Reference Connection) 을 근간으로 해서 ISDN 의 신뢰도 목표치와 가용도 목표치를 제시하였다 Bellcore에서 제시한 ISDN 스위칭 시스팀의 신뢰도 성능 목표치는 22개의 신뢰도 파라미터와 목표치로 정의 되었으며, 22개의 신뢰도 파라미터 는 Downtimes, cutoff call probability, Ineffective machine attempt(IMA) probability 와 Failure intensity 등 4개의 종류로 나누어서 제시하였다.

겉보리 및 쌀보리의 수화속도

이종숙,김성곤,Lee, Jong-Sook,Kim, Sung-Kon 한국식품과학회 1983 한국식품과학회지 Vol.15 No.3

겉보리(올보리와 강보리) 및 쌀보리(세도하다가와 백동)를 각각 40 및 30%도정한 다음, 20, 30 및 $40^{\circ}C$에서 6시간 침지하면서 수화속도를 검토하였다. 수화속도는 수화시간의 평방근에 비례하였고, 확산계수 ($D,\;cm^{2}/min$)는 D = $D_{0}\;{\exp}\;(-E_{a}/RT)$로 표시되었다. 확산계수 값은 강보리가 돌보리보다 다소 높았으며, 세도하다가와 백동은 비슷하였다. 쌀보리의 확산계수는 겉보리보다 다소 높았다. The hydration of water, at $20^{\circ}\;30^{\circ}$ and $40^{\circ}C$ for 10-360 minutes, by the two varieties of husked barley and of naked barley which were polished to 40 and 30%, respectively, was investigated. The absorption was directly proportional to the square root of the hydration time and accounted for by the diffusion equation: 1-M = $(2/{\sqrt\pi})\;(S/V){\sqrt{Dt}}$, where 1-M is the relative moisture gain and S/V is the surface-to-volume ratio. The average diffusion coefficient (D) was given by the Arrhenius relation: D = $D_{0}\;exp\;(-Ea/RT)$, where the activation energy for both husked and naked barley was about 7.2 Kcal/mole. The average value of D for naked barley was slightly higher than that for husked barley.