암 치료 소외계층을 위한 암 의료이용 체계 구축의 모색: 환자 네비게이션(Patient Navigation) 프로그램 중심으로

이영선 ( Lee Young Sun ),이송이 ( Lee Song Yi ),한인영 ( Han In Young ) 한국보건사회연구원 2011 保健社會硏究 Vol.31 No.3

전 세계적으로 암 발생률과 사망률, 암관리비용이 증가하고 있다. 우리나라 또한 사회경제적 수준에 따라 암 치명률과 사망률의 격차를 보일 뿐 아니라, 오히려 사회경제 적 취약계층 일수록 암 치료를 위한 의료이용에서 소외되는 건강불평등 양상이 나타나 기 시작했다. 따라서 효과적이고 효율적인 의료재원 활용의 필요성이 제기되고 있다. 외국의 경우 우리보다 앞서 암 치료 소외계층이 의료 서비스 이용 과정에서 겪게 되는 물리적 ? 경제적 장애요소에 적절히 개입하여 의료이용 접근성을 높이기 위한 `환자 네 비게이션 프로그램`이 개발 ? 적용되고 있으며 지속적으로 여러 연구를 통해 프로그램의 효과가 검증되고 있다. 미국 및 캐나다에서 진행된 200개 이상의 환자 네비게이션 프로그램을 통해 사회경제적 취약계층이 암 의료이용 시 겪게 되는 경제적 어려움, 물리 적으로 낮은 이용 접근성, 문화적 차이와 언어적 제약, 분절된 서비스 전달체계, 인종에 따른 차별 등을 줄이고 암 의료이용에의 접근성을 높인 결과 암 생존율이 높아진 것으로 보고되었다. 이러한 검토에 따라 우리나라 암 치료 소외계층의 의료이용 형평성 제 고를 위한 환자 네비게이션 프로그램 적용 가능성 탐색을 위해서는 우선 암 환자 및 가족 등 프로그램 대상자의 요구도 조사가 이뤄져야 하며 운영 주체를 통한 원활한 프로그램의 기틀 마련, 그리고 네비게이터의 발굴이 이뤄져야 한다. 한국형 환자 네비게 이션 프로그램의 성공적인 적용을 위해서는 암 환자 의료이용 실태에 대한 체계적인 조 사와 네비게이터 양성을 위한 교육 프로그램이 과제로 제시되었다. The rate of cancer and the cost of treatment for cancer have increased exponentially worldwide. Given the social costs attributed to the rising rate of cancer-related mortality and death, medical inequality became an issue, and there is a recognized need for effective medical support for cancer patients. In several countries, the Patient Navigation Program, a systematic cancer prevention and intervention program designed to be accessible to Health care disparities in need of cancer treatment, has been reported to be effective. The focus of the study is to investigate the characteristics of Patient Navigation Program and to examine the feasibility of the program in South Korea. The navigation program train paraprofessionals to provide intervention services for cancer patients who experience barriers to medical services. Presently, there are over 200 Navigation Programs in the United States and Canada. As a result, the program has been found to be effective as increasing number of low-income patients have access to medical service which has reportedly decreased the rate of cancer-related mortality. In order to examine whether such program would be as effective in South Korea, our study examines the background and characteristics of Navigation Program use. There is a need for survey for data base for cancer patient service utility and develop navigator training program. The navigation program will decrease the rate of cancer related mortality and serve for medical inequality.

류마티스 관절염에 대한 한약의 면역학적 연구동향

최도영,이재동,백용현,이송실,유명철,한정수,양형인,박상도,유미현,박은경,박동석,Choi, Do-young,Lee, Jae-dong,Back, Yong-hyeon,Lee, Song-shil,Yoo, Myung-chul,Han, Chung-soo,Yang, Hyung-in,Park, Sang-do,Ryu, Mi-hyun,Park, Eun-kyung,Park, 대한침구의학회 2004 대한침구의학회지 Vol.21 No.4

Objective : Rheumatoid arthritis is an autoimmune disease that pathogenesis is not fully understood and one of the most intractable musculoskeletal diseases. The concern in the immunopathogenesis of rheumatoid arthritis has been increased since 1980's and many immunotherapeutic agents including disease-modifying antirheumatic drugs (DMARDs) were developed and became the mainstay of treatment of rheumatoid arthritis. However, the cure of the disease has hardly been achieved. In oriental medicine, rheumatoid arthritis is related to Bi-Zheng(痺證), that presents pain, swelling, andlor loss of joint function as major clinical manifestations, and also known to be deeply involved in suppression of immune function related to weakness of Jung-Ki(正氣). The herbal medicine, empirically used, could be a potential resource of development of new immunotherapeutic agents for rheumatoid arthritis. Methods : We developed a search strategy using terms to include "rheumatoid arthritis and herbal medicine" combined with "Chinese medicine" and/or "Oriental medicine". The search was focused on experimental studies of herbal medicine (January 1999 to May 2004), which is known to have effects on immune function of patients with rheumatoid arthritis. Computerized search used Internet databases including KISS and RISS4U (Korea), CNKI (China), MOMJ (Main Oriental Medicine Journal, Japan), and PubMed. The articles were selected from journals of universities or major research institutes. Results : The literature search for experimental studies on effects of herbal medicine on immunity of rheumatoid arthritis retrieved a total of 21 articles (Korea; 8, China ; 12, Japan ; 1). Of 21 articles, 10 were related to single-drug formula, 2 to drug interaction, and 9 to multi-drug formula. Single-drug formula was mainly used for aqua-acupuncture and researches on active components. Studies of drug interaction emphasized harmony of Ki-Hyul(氣血) and balance of Han-Yeul(寒熱). Multi-drug regimen was mainly found among formulas for Bo-Ki-Hyul(補氣血) and Bo-Sin(補腎). Conclusion : Studies on rheumatoid arthritis were performed both in vitro and in vivo in vitro study, LPS-stimulated splenocytes and synoviocytes were treated with herbal medicine, resulting in proliferation and activation of immune cells and suppression of cytokine activities in vivo study CIA animal model demonstrated that herbal medicine decreased antibody production and improved function of immune cells. In cellular and molecular study herbal medicine showed profound effects on the level of mRNA expression of certain cytokines related to immune function. This study revealed that herbal medicine has significant immune modulatory action and could be used for recovery of immune dysfunction of rheumatoid arthritis patients.

대구지역 내 일부 치과기공소의 공기 중 석면농도

임무혁 ( Moo Hyuk Lim ),이송권 ( Song Kwon Lee ),정인호 ( In Ho Jung ) 한국산업위생학회 2004 한국산업보건학회지 Vol.14 No.3

This study was performed to investigate the problems of using asbestos for dental technicians. Samples for analyzing were sampled by personal sampler in 40 sampling points of 10 dental laboratories in Daegu city from December, 2003 to February, 2004 and counted with phase contrast microscopy. The results were as follows: 1. Asbestos concentration(geometric mean) of 40 sampling points in 10 dental laboratories was 0.0061 f/cc and it was under recommended industrial and indoor air standard, but the concentration of asbestos in only two dental laboratories was over indoor recommended standard. 2. The concentration of asbestos in processing room and burnout room was 0.0099 f/cc and 0.0037 f/cc, respectively. 3. The mean concentration(GM) of asbestos by kinds of casting ring liners was 0.0159 f/cc in dental laboratories using industrial asbestos, 0.0104 f/cc in them using asbestos containing ring liners, and 0.0026 f/cc in them using non-asbestos ring liners. Casting ring liners using in dental laboratories should be substituted with non-asbestos liners, because most of dental laboratories were using asbestos containing ring liners and a few of them showed higher concentration than recommended standard.

전북지역 간척지에서 최고품질 벼 품종의 작물학적·이화학적 특성 비교 및 선발

최창학,김갑철,이덕렬,조승현,조대호,이송이,이인석,Choi, Chang-Hak,Kim, Kab-Cheol,Lee, Deok-Ryeol,Cho, Seung-Hyun,Cho, Dae-Ho,Lee, Song-Yi,Lee, In-Sok 한국작물학회 2018 한국작물학회지 Vol.63 No.3

The main objective of this study was to identify the best quality rice for cultivation on reclaimed land in Jeollabukdo-Province based on yield, head rice ratio, protein content, amylose content, and Toyo taste value evaluations. Seven varieties of rice were grown for two years on the reclaimed land. The Sukwang variety had the earliest heading date. The tiller number for the Younghojinmi variety was 19 on average, and its variation in tiller number was the lowest, which showed that the safety for cultivation of the variety was high on the reclaimed land with respect to that of the other varieties. The culm and panicle lengths of the Sukwang and Hyunpum varieties were the highest at 81.8 and 21.3 cm, respectively. Shindongjin produced the highest thousand grain weight at 27.7 g, whereas Haepum produced the lowest at 22.3 g. The number of grains per panicle for 7 all varieties was statistically equal for both years. The yield order for the varieties was Shindongjin (590) > Hopum (575) > Younghojinmi (552) > Sukwang (551) > Hopum (543) > Mipum (534) > Haepum (498 kg/10a), which showed that there was no significant difference in average yield between the varieties when both years are taken into consideration. However, the annual difference in Haepum yield between 2015 and 2016 was the highest at 108 kg/10a, indicating low cultivation safety. The head rice ratio of Younghojinmi was higher than for the other cultivars in both 2015 and 2016. However, there was no significant difference between the 2 years when the averages for all varieties were analyzed. There was was a considerable difference in protein and amylose content between the varieties in the two years, although this was not apparent in the results when the average over 2 years for each variety was calculated. There was no significant difference between the two years with respect to the average head rice ratio, and the protein and amylose contents of the seven varieties. The Toyo taste values for the Sukwang and Mipum varieties were higher than for the other varieties. Based on the principle characteristics, such as Toyo value, the Sukwang variety is a suitable substitute for Shindongjin, which has been previously used to produce high-quality rice on the reclaimed land.

소형펀치-크리프 시험에 대한 응력해석과 일축 크리프 시험과의 상관성에 관한 연구

이송인,백승세,권일현,유효선,Lee, Song-In,Baek, Seoung-Se,Kwon, Il-Hyun,Yu, Hyo-Sun 대한기계학회 2002 大韓機械學會論文集A Vol.26 No.12

A basic research was performed to ensure the usefulness of Small Punch-creep(SP-creep) test for residual life evaluation of heat resistant components effectively. This paper presents analytical results of initial stress and strain distributions in SP specimen caused by constant loading for SP-creep test and its experimental correlations with uniaxial creep(Ten-creep) test on 9Cr1MoVNb steel. It was shown that the initial maximum equivalent stress, ${\sigma}_{eq{\cdot}max}$ from FE analysis was correlated with steady-state equivalent creep strain rate, ${\epsilon}_{qf-ss'}$ rupture time, $t_r$, activation energy, Q and Larson-Miller Parameter, LMP during SP-creep deformation. The simple correlation laws, ${\sigma}_{sp}-{\sigma}_{TEN}$, $P_{sp}-{\sigma}_{TEN}\; and\; Q_{sp}-Q_{TEN}$ adopted to established a quantitative correlation between SP-creep and Ten-creep test data. Especially, the activation energy obtained from SP-creep test is linearly related to that from Ten-creep test at $650^{\circ}C$ as follows : $Q_{SP-P}\;{\risingdotseq}\;1.37 \;Q_{TEN},\; Q_{SP-{\sigma}}{\risingdotseq}1.53\; Q_{TEN}$.

국부변형률근사법을 이용한 차체 점용접부의 피로수명 예측에 관한 연구

이송인,권일현,이범준,유효선,Lee, Song-In,Gwon, Il-Hyeon,Lee, Beom-Jun,Yu, Hyo-Seon 대한기계학회 2001 大韓機械學會論文集A Vol.25 No.2

The fatigue crack initiation life is studied on automotive tensile-shear spot weldment made from cold rolled carbon steel(SPC) sheet by using DCPDM and local strain approach. It can be found that the fatigue crack initiation behavior in spot weldment can be definitely detected by DCPDM system. To predict the fatigue life of spot weldment, the local stresses and strains at the potential critical region are estimated by approximate method based on Neubers rule and elastic-plastic FEM analysis. A satisfactory correlation between the predicted life obtained from Local strain approach based on Neubers rule and experimental life can be found in spot weldment within a factor of 2.

자긴가공된 두꺼운 실린더의 피로균열 전파수명평가

이송인,김진용,정세희,고승기,Lee, Song-In,Kim, Jin-Yong,Jeong, Se-Hui,Go, Seung-Gi 대한기계학회 1998 大韓機械學會論文集A Vol.22 No.2

To ensure the structural integrity of the autofrettaged thick-walled cylinder subjected to cyclic internal pressure loading, the fatigue crack propagation life of the cylinder was evaluated. Stress intensity factors of the external cracked cylinder due to internal pressure and autofrettage loadings were calculated using the finite element method. The fatigue crack propagation lives of the cylinder based on the fracture mechanics concepts were predicted and compared to the experimental fatigue lives evaluated from the C-shaped simulation specimens. There were good correlations between the predicted and experimental fatigue lives within a factor of 3 for the single and double grooved C-shaped simulation specimens. Predicted fatigue crack propagation lives of the double grooved cylinders were about 1.5-5 times longer than those of the single grooved cylinders depending on the levels of autofrettage.

한천분해효소를 생산하는 Agarivorans sp. JA-1의 배양조건 및 Fed-batch 배양

이송애(Song-Ae Lee),김진욱(Jin-Uk Kim),정종근(Jong-Geun Jung),김인혜(In Hae Kim),이상현(Sang-Hyeon Lee),김상진(Sang-Jin Kim),이재화(Jae-Hwa Lee) 한국생물공학회 2006 KSBB Journal Vol.21 No.5

원격 자동 제어 전기난로

이송형(Song-Hyung Lee),김태권(Tae-Kwon Kim),이원형(Won-Hyung Lee),김민조(Min-Jo Kim),강은비(Eun-Bi Kang),배병인(Byung-In Bae) 대한전기학회 2018 대한전기학회 학술대회 논문집 Vol.2018 No.-

A Study on the Intellectual Property Rights in Outer Space : Legal Issues and Improvement of Policy

Song-In Lee(이송인),Dae-Young Lee(이대영) 한국항공우주학회 2023 한국항공우주학회 학술발표회 논문집 Vol.2023 No.6