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유미현 남서울대학교보건의료개발연구소 2004 보건복지 연구 논집 Vol.1 No.1
The aim of the present study was to investigate whether epidermal growth factor recetor(EGFR) are expressed in oral irritation fibroma. Irritation fibromas from 90 patients and control normal mucosa were studied by immunohistochemistry using EGFR. Immunohistochemistry demonstrated that the overlying mucosa of irritation fibroma revealed the strong positive expression in the prickle layer. And fibroblasts in the mass of irritation fibroma showed restricted positive expression. The macropages and fibroblasts located in the subepithelial area and the vessles in the mass of irritation fibroma showed strong positive expression. These suggest that EGFR expression by overlying epithelium, the autocrine and paracrine stimulation by EGFR in the fibroblasts and macrophages and angiogenesis via EGFR may be involved in the pathogenesis of oral irritation fibroma.
유미현 남서울대학교보건의료개발연구소 2005 보건복지 연구 논집 Vol.2 No.1
In this study, we have investigated the smoking pattern of the students in Namseoul University. The 156 students were recruited as subjects. Questionnaire survey was performed about current smoking pattern, past smoking pattern, present oral diseases and the awareness between the smoking and oral diseases. The smoking rate of the students was 28.8% and among ex-smokers, 64.9% of smokers had smoked during 5-10 years. The 50.8% of current smokers smoked 10 cigarettes per day. The reasons of quit-smoking were due to health's condition 35.7%, harmful to health 22.8%. The 90.5% of smokers never had used the quit smoking appratus and 49.1% participated in the program of quit smoking. The awareness of relationship between smoking and oral disease was 92.9%. An understanding of the characteristics of smoking of the students and awareness of relationship between smoking and oral disease may provide guidance for preventive quit smoking program with adolescents.
신성 골이영양증의 구강내 증상으로 나타난 하악골의 국소적 증대 -1례 보고-
유미현,김현실,지유진,송현철,김진 대한구강악안면병리학회 2009 대한구강악안면병리학회지 Vol.33 No.2
Renal osteodystrophy is the complex disease of the skeleton that occurs in patients with chronic renal failure. A 29-year-old female with chronic renal failure and a history of hemodialysis during 10 years showed localized jaw enlargement in the anterior mandible. She also revealed increased serum PTH level, osteosclerosis in her skull base and facial bone, chronic pain in the both knee joint, and gastrointestinal disorder which are symptoms of renal osteodystrophy. The patient was diagnosed hyperparathyroidism associated with chronic renal failure. Parathyroidectomy was performed, however, serum PTH level increased again after the parathyroidectomy, the affected area of the mandible was enlarged as the serum PTH level increased. The enlarged area seemed like as peripheral lesion clinically. We reported a case of localized jaw enlargement as oral manifestation in renal osteodystrophy.
유미현 남서울대학교보건의료개발연구소 2005 보건복지 연구 논집 Vol.2 No.1
In this review we have elected to discuss those diseases of systemic diseases have significant manifestations in oral cavity. Many systemic diseases can occur or show symptoms in oral cavity. Brief outline of the pathogenesis, epidermiology, and systemic components of each disease is given, followed by a more detailed analysis of the oral manifestations.