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이새벽 ( Sae-byeok Lee ),백수경 ( Soo-kyung Baek ),안정려 ( Jeong-ryeo Ahn ),이정민 ( Jeong-min Lee ) 한국미용예술경영학회 2013 미용예술경영연구 Vol.7 No.2
Human and disease were considered to be uniform without regarding physical constitution of each individual but Dr. jema-lee was established Yin and Yang according to the physical characteristics in 1984. Therefore fashion effected by personal preference is also affected by Yin and Yang. In this study, by presenting the fashion regarded Yin and Yang, not only fashion but also mental will be developed. Tae-yang has image of progressive, personality tendencies to act like men so modern, mannish and elegance are suitable. So-eum has Neat and calm, sociable personality that make a good impression on others so romantic, pretty, casual and active image are suitable. Tae-eum is shy, feminine and consistency so elegance, ethnic are suitable. So-yang has personality tendencies to be outgoing, cheerful, and witty so image of chic, elegance and sporty are suitable for fashion. Research for Yin and Yang in the field of make-up, nail according to the harmony has to be done constantly.
실시간 학습평가 및 학습 액티비티 결과 수집을 이용한 학습자 프로파일링
이새벽 ( Sae Byeok Lee ),지혜성 ( Hye Sung Ji ),유원희 ( Won Ee Yu ),임희석 ( Heui Seok Lim ) 한국컴퓨터교육학회 2013 한국컴퓨터교육학회 학술발표대회논문집 Vol.17 No.2
컴퓨터를 이용한 교수-학습 환경은 온라인의 대중화와 더불어 이제 낯설지 않은 환경이다. 이런 컴퓨터를 이용한 교수-학습 환경에서 학습자에게 맞춤형 학습을 제공하기 위해서는 학습자를 잘 분류해야 한다. 따라서 본 논문에서는 지능형 튜터링을 위해 학습관리시스템과 퀴즈, 설문, 교실 모니터링 등 여러 학습 활동을 지원하는 학습활동지원도구의 이력데이터에서 학습자의 프로파일을 만드는 방법에 대해서 제안한다. 제안하는 학습자 프로파일링은 이력데이터로부터 이해도, 집중도, 학습태도를 계산하여 학습자의 학습능력과 학습 상태를 진단할 수 있도록 제공한다. 각 측정값이 각 수업에 대한 학생의 절대적인 이해도, 집중도가 될 순 없지만, 시스템에서 이런 정보를 자동으로 생성하고 제공함으로써 지능적으로 맞춤형 콘텐츠를 제공하는데 도움이 될 수 있을 것이다.
무어링라인 긴장력 관리를 위한 E/M센서의 자화구조 개선
이호준 ( Lee Ho-jun ),경새벽 ( Kyung Sae-byeok ),전교영 ( Jeon Kyoyoung ),김주원 ( Kim Ju-won ) 한국구조물진단유지관리공학회 2023 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.27 No.1
부유식 풍력발전 구조물에서 계류삭(Mooring line)은 해저지반과 부유식 플랫폼을 연결하여 구조물의 위치와 균형을 유지하는 구조적 안전을 위한 중요한 부재이다. 특히 TLP(Tensing Leg Platform)와 같은 인장 계류 방식에서 계류삭의 긴장력을 유지하는 것은 구조물의 안전성에 절대적인 영향을 미친다. 본 연구에서는 계류삭의 긴장력 관리를 목적으로 E/M(Elastomagnetic)센서를 이용한 B-H loop 기반의 비파괴검사 기법을 적용하였다. 특히 기존 솔레노이드 방식의 자화구조에서 요구되던 현장권선의 한계를 극복하여 사용성을 높이고자 분할형 요크방식으로 자화구조를 개선하였고, 이를 적용한 무어링라인 긴장력 추정 성능을 확인해 보았다.
김세미,신새벽,강현아,조혜영,이용복,Kim, Se-Mi,Shin, Sae-Byeok,Kang, Hyun-Ah,Cho, Hea-Young,Lee, Yong-Bok 대한약학회 2008 약학회지 Vol.52 No.4
Gabapentin, 1-(aminomethyl) cyclohexaneacetic acid, is a amino acid derivative, and is clinically effective in the treatment of neuropathic pain and partial seizures of epilepsy as a complementary therapy. The purpose of the present study was to evaluate the bioequivalence of two gabapentin tablets, $Neurontin^{R}$ tablet 800 mg (Pfizer Pharmaceuticals Co., Ltd.) and Gabapenin tablet 800 mg (Hanmi Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of gabapentin from the two gabapentin formulations in vitro was tested using KP VIII Apparatus II method with 0.06 M HCI dissolution media. Twenty six healthy male subjects, $23.85{\pm}2.24$ years in age and $69.40{\pm}11.11$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ crossover study was employed. After a single tablet containing 800 mg as gabapentin was orally administered, blood samples were taken at predetermined time intervals and the concentrations of gabapentin in serum were determined using HPLC with fluorescence detector. The dissolution profiles of two formulations were similar in the tested dissolution media. The pharmacokinetic parameters such as $AUC_{t}$, $C_{max}$ and $T_{max}$ were calculated, and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_{t}$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Neurontin^{R}$, were 1.28%, 0.63% and 0.62% for $AUC_{t}$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., $log0.9097{\sim}log1.1598$ and $log0.8919{\sim}log1.1262$ for $AUC_{t}$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Gabapenin tablet 800 mg was bioequivalent to $Neurontin^{R}$ tablet 800 mg.
양영욱 ( Yeong-wook Yang ),이새벽 ( Sae-byeok Lee ),임희석 ( Heui-seok Lim ) 한국정보처리학회 2012 한국정보처리학회 학술대회논문집 Vol.19 No.2
외국어 능력이 현대 사회에서 요구하는 필수적인 요소 중에 하나이다. 본 논문에서는 기존의 외국어 능력을 평가하는 능력 시험이 아닌 언어심리학적 관점으로 외국어 능력을 평가하는 방법을 제안한다. 외국어를 처리하는데 있어서 외국어를 모국어를 바꾸는 언어인지 과정이 필요하다. 본 논문에서는 이러한 언어 인지 능력을 측정하는 Reading LDT, Listening LDT, Verbal Span, Yes-No task(Semantic), Same-Different task실험을 제안한다. 해당 과제들은 각각 피험자의 읽기, 듣기, 기억, 의미적 결정, 변환 능력을 측정하는 과제이다.
김세미,강현아,조혜영,신새벽,류희두,윤화,이용복,Kim, Se-Mi,Kang, Hyun-Ah,Cho, Hea-Young,Shin, Sae-Byeok,Yoo, Hee-Doo,Yoon, Hwa,Lee, Yong-Bok 대한약학회 2008 약학회지 Vol.52 No.3
Gabapentin, [1-(aminomethyl) cyclohexaneacetic acid], a structural analog of $\gamma$-aminobutyric acid (GABA), is being developed for the treatment of epilepsy. Unlike GABA, gabapentin crosses the blood-brain barrier after systemic administration. Gabapentin is an effective antiepileptic drug in patients with partial and secondarily generalized seizures who are uncontrolled with use of existing anticonvulsant drug therapy. The purpose of the present study was to evaluate the bioequivalence of two gabapentin 400 mg capsules, $Neurontin^{(R)}$ capsule 400 mg (Pfizer Inc.) and Gabatin capsule 400 mg (Korean Drug Co. Ltd), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of gabapentin from the two gabapentin formulations in vitro was tested using KP VIII Apparatus II method with various dissolution media (pH 1.2, 4.0, 6.8 buffer solution and water). Twenty six healthy male subjects, 23.58$\pm$1.50 years in age and 66.74$\pm$8.31 kg in body weight, were divided into two groups and a randomized 2$\times$2 cross-over study was employed. After one capsule containing 400 mg as gabapentin were orally administered, blood was taken at predetermined time intervals and the concentrations of gabapentin in serum were determined using HPLC with fluorescence detector. The dissolution profiles of two formulations were similar at all dissolution media. In addition, the pharmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Neurontin^{(R)}$ capsule 400 mg, were 2.04, -3.68 and 16.79% for $AUC_t$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., log 0.91$\sim$log 1.16 and log 0.87$\sim$log 1.11 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Gabatin capsule 400 mg was bioequivalent to $Neurontin^{(R)}$ capsule 400 mg.