Outcomes of Diffuse-Type Pigmented Villonodular Synovitis (PVNS) after Open Total Synovectomy

이모세,이수현,서진석,양우익,신규호,Lee, Mo-Ses,Lee, Soo-Hyun,Suh, Jin-Suck,Yang, Woo-Ik,Shin, Kyoo-Ho The Korean Musculoskeletal Tumor Society 2010 대한골관절종양학회지 Vol.16 No.1

목적: 색소 융모 결절성 활액막염은 슬관절을 비롯한 주요 관절에서 드물게 발생하는 연부 조직 종양으로서 수술 적 치료 후 재발 빈도가 높은 것으로 알려져 있다. 본 연구에서는 주요 관절에 발생한 미만형 색소 융모 결절성 활액막염에 대한 활막 전 절제술 후 임상 경과를 보고하고, 기존에 발표 된 문헌과 비교 분석하고자 한다. 대상 및 방법: 1994년 2월부터 2006년 3월까지 미만형 색소 융모 결절성 활액막염으로 치료 받은 21예의 환자를 대상으로 하였으며, 발생 부위는 슬관절 14예, 족관절 5예, 견주관절 2예가 있었다. 평균 추시 기간은 5년 5개월이었다(36-157개월). 발생 연령은 평균 34세였으며 남자가 7명, 여자가 14명이었다. 후향적 연구 방법으로 관절 운동 범위 측정을 포함한 정기적인 임상 양상 평가를 하였다. 결과: 총 21예의 미만형 환자 중 1예를 제외 한 전례에서 활막 전 절제술 및 전기소작술을 통한 보강 치료를 시행하였으며, 정기적인 외래경과 관찰 상 재발이 의심되었던 2예에서 재수술 후, 1예에서만 조직학적 재발이 확진 되었다. 활막 전 절제술을 시행하지 못한 1예와, 재발로 재수술 받은 1예에서 술 후 방사선 치료를 시행 하였다. 임상 기능 평가상 술전과 비교하여 모든 부분에서 통계적으로 유의한 호전이 있었다.(p<0.0001). 슬관절에 발생한 병변으로 수술적 치료를 시행 후 관절 운동 장애로 제약이 있던 환자는 2예(총 14예) 있었다. 결론: 최소 3년 이상의 추시 기간 동안 활막 전 절제술 및 전기 소작술을 통한 보강 치료로 호전된 임상 결과 및 낮은 재발율의 치료 효과를 얻을 수 있었다. 잦은 재발과 주요 관절에 발생하여 국소적 침투, 파괴로 기능 장애를 일으키는 미만형 색소 융모 결절성 활액막염에 치료에 있어 적절한 활막 전 절제술이 시행 될 경우 방사선 보강 치료는 제한 된 경우에만 필요할 것이다. Purpose: Pigmented villonodular synovitis (PVNS) is a rare soft tissue tumor, which usually arises in larger joints, such as the knee. It has a high recurrence rate after surgical treatment. The purpose of this study is to evaluate and analyze the clinical results of diffuse-type pigmented villonodular synovitis cases that were treated with open total synovectomy. Materials and Methods: Between 1994 and 2006, 21 patients who had diffuse-type pigmented villonodular synovitis were selectively reviewed. Among the 21 cases studied, 14 patients presented at the knee, 5 at the ankle, and 2 at the shoulder and elbow. The mean follow up period was 5.5 years (range, 36-157 months). The average age of the patients was 34 years consist of 7 men and 14 women. Clinical outcomes were analyzed retrospectively, including range of motion and complications. Results: Open total synovectomy and adjuvant electrocautrization were done in all cases except one. During the regular follow-up period after the surgery, two patients showed symptoms of recurrence. After re-operation, only one case was pathologically confirmed as a recurrence. The patient who had partial synovectomy and the other patient who had second operation due to recur rence received additional radiation therapy. Clinical outcome scores were improved in every aspect (p<0.0001). 2 out of 14 Patients who had pigmented villonodular synovitis at the knee developed stiff knee after the surgery. Conclusion: After the open total synovectomy with electrocautrization, a low recurrence rate and satisfactory clinical outcome was achieved, observed in a minimum of 3 years of follow-up.

‘동작에 대한 분명한 앎’과 삼빠잔냐에 대한 고찰

이모정(Lee, Mojung) 불교학연구회 2018 불교학연구 Vol.56 No.-

본 연구는 초기불교 사념처의 ‘동작에 대한 분명한 앎’의 의의와 위상을 밝히고 ‘동 작에 대한 분명한 앎’의 내적 기제인 ‘삼빠잔냐’의 쓰임을 초기경전에서 살펴봄으로써그 의미와 사띠와의 관계를 밝혔다. 이는 ‘동작에 대한 분명한 앎’의 현대적 변용이 무엇 일까를 연구하기 위한 목적이다. ‘동작에 대한 분명한 앎’은 일상생활의 행위와 동작을 알아차리는 수행이다. 초기 경전에서 ‘동작에 대한 분명한 앎’은 사념처의 21가지 주제에서도 특히 강조되고 있는 수행법이라 할 수 있다. 승가생활의 행위 전체가 수행의 대상이 되어 한 순간도 방일하지 않고 분명히 알아차려 계를 지키고 지혜를 계발하게 하는 강력한 일상수행이라볼 수 있다. 경전에서 ‘동작에 대한 분명한 앎’의 내적 기제인 삼빠잔냐의 경전에서의 쓰임과 의미를 살펴보고, 불교수행의 핵심기제인 사띠와의 관계를 고찰하였다. 초기 경전에서 삼빠잔냐는 거의 사띠와 함께 쓰여 대상을 포착하고 대상을 분명히 아는 기능들이 상보적으로 작용하며 지혜를 계발하게 하였다. 그러나 삼빠잔냐가 단독으로 쓰인 경우는 단지 어떠한 사실을 알지만 지혜의 요소는 결여되어 있음을 알아보았다. ‘일상생활명상’이 라는 측면에서 ‘동작에 대한 분명한 앎’의 현대 명상적 의의와 그 가능성을 살펴보고, 일상생활에서 걷기 뿐 아니라 그릇을 씻는 행위에서도 ‘동작에 대한 분명한 앎’을 적용시켜 보았다. 본 연구는 경전에서 삼빠잔냐의 쓰임을 고찰하였다는 점과 ‘동작에 대한 분명한 앎’ 의 현대 일상생활명상으로의 가능성과 적용을 살펴보았다는 점에서 의의가 있다. This aim of this study is to examine the modern transformation of ‘Clear Comprehension of Movement’. To meet this goal, I examined the significance and status of ‘Clear Comprehension of Movement’ in Early Buddhism and revealed the relationship between the ‘Clear Comprehension of Movement’ and Mindfulness (Sati) by investigating the use of Sampajañña, the inner mechanism of ‘Clear Comprehension of Movement’, in the Early Buddhist texts. ‘Clear Comprehension of Movement’ is a practice to be aware of the act and behavior of everyday life. In the early scriptures, ‘Clear Comprehension of Movement’ is a particularly emphasized practice in 21 subjects of the Cattāro Satipaṭṭhanā. It is a powerful daily practice in which the monk’s whole life becomes an object of performance, keeping a clear perception and developing wisdom. In the early scriptures, Sampajañña was almost used along with Sati for complementary action of functions that capture the object and know the object clearly, which leads to developing wisdom. However, when Sampajañña was used alone, he knew that he only knew some facts but lacked elements of wisdom. I examined the possibility of practicing meditation in everyday life with contemporary meaning of ‘Clear Comprehension of Movement’ and applied ‘Clear Comprehension of Movement’ in the daily life such as washing dishes. The significance of this study is that the application of ‘Clear Comprehension of Movement’ to modern daily practice was proved to be possible and that the use of Sampajañña in early Buddhist texts was examined carefully.

SRGAN을 활용한 Sentinel-2 영상의 초해상화와 GEDI LiDAR를 통한 캐노피 추정

이모세(Lee, Mose),양병윤(Yang, Byungyun) 한국측량학회 2023 한국측량학회지 Vol.41 No.6

기후변화로 인한 산림 생태계의 변화 파악이 중요해지면서 지상 바이오매스를 추정하는 연구가 꾸준히 수행됐다. 지상 바이오매스를 추정하는 연구는 현장에서 직접 측량하거나 항공 및 위성영상을 활용하는 방식을 널리 사용했다. 이 방법들은 높은 비용, 인력문제, 자료 취득의 문제, 연구지역 범위 설정 등의 문제가 있어 무료로 제공되는 위성영상 자료의 활용이 불가피하게 됐다. 따라서 본 연구에서는 SRGAN을 활용한 Sentinel-2 이미지의 초해상화(Super-Resolution)와 GEDI (Global Ecosystem Dynamics Investigation) LiDAR를 활용하여 산림 캐노피의 높이를 추정하려는 목표를 가진다. 구체적으로 초해상화 과정은 GAN기반 네트워크인 SRGAN을 활용해 10m의 공간해상도를 가진 Sentinel-2 이미지를 2.5m로 초해상화 하였다. 이를 통해 개선된 Sentinel-2 이미지를 활용해 산림의 변화탐지 가능성을 파악했다. 다음으로 GEDI 데이터로부터 캐노피 높이 값을 추출하여 일반 크리깅과 역거리가중법을 통해 미측정 지역에 대한 보간을 수행하여 넓은 지역에 대한 산림 캐노피 높이를 추정했다. 마지막으로 산림 캐노피의 평균값 및 분포를 분석하고, GEDI와 Sentinel-2 데이터를 활용하여 보다 정밀한 산림 생태계 파악을 가능하게 하였다. 따라서 본 연구를 통해 광범위한 지역을 커버할 수 있는 비용 효율적인 방법의 산림 생태계 모니터링 방식을 제안하여 산림 관리와 보존에 있어 지속 가능한 산림 관리에 기여할 것으로 기대한다. The increasing importance of understanding the changes in forest ecosystems due to climate change has led to consistent research in estimating AGB (Above-Ground Biomass), which typically involves surveying or the use of aerial and satellite imagery. These methods, however, face challenges related to cost, labor, and determining the size of research areas. For the reason, it is unavoidably relying on freely available satellite imagery data. Thus, this study aims to use SRGAN (Super-Resolution Generative Adversarial Network ) for enhancing the resolution of Sentinel-2 images and to estimate forest canopy height using GEDI (Global Ecosystem Dynamics Investigation) LiDAR. Specifically, the super-resolution process employed SRGAN to enhance the 10m spatial resolution of Sentinel-2 images to 2.5m, improving the ability to detect changes in forests using Sentinel-2 images. Furthermore, canopy height values from GEDI data were interpolated for unmeasured areas using OK (Ordinary Kriging) and IDW (Inverse Distance Weighting), allowing for the estimation of forest canopy height over a large area. Finally, this study analyzed the average values and distribution of the forest canopy, and utilized both GEDI and Sentinel-2 data for a more precise understanding of the forest ecosystem. Therefore, this research proposes a cost-effective method for extensive forest ecosystem monitoring, contributing to sustainable forest management and conservation.

스마트시티를 위한 실시간 데이터 처리 아키텍처

이모세(Mo-se Lee),강민수(Min-su Kang),김홍준(Hong-joon Kim),김재헌(Jae-hun Kim) 한국통신학회 2021 韓國通信學會論文誌 Vol.46 No.2

총채벌레 및 고추탄저병의 동시 방제를 위한 곤충병원성 곰팡이 Isaria javanica FT333 선발

이모란 ( Moran Lee ),정혜주 ( Hyeju Jeong ),김재윤 ( Jaeyoon Kim ),김다연 ( Dayeon Kim ),안성호 ( Seung Ho Ahn ),이상엽 ( Sangyeob Lee ),한지희 ( Ji Hee Han ) 한국균학회 2018 韓國菌學會誌 Vol.46 No.4

Red pepper is seriously damaged by thrips (Thrips palmi) and anthracnose caused by Colletotrichum acutatum throughout its development. Because of biotic constraints, producers often depend on chemicals that are expensive and have adverse effects on the environment, operator, and beneficial insects. In addition, resistance is developed because of the repeated use of chemicals. In recent decades, the use of microorganisms in crop protection has become a credible alternative because it is eco-friendly. In this study, we aimed to select isolates with insecticidal and fungicidal activities against the pathogens that cause anthracnose and thrips. We treated T. palmi adults and juveniles with 13 strains of entomopathogenic fungi (isolated from the soil by using the insect-bait method), and 6 strains showed excellent insecticidal activity (70-100%) 5 days after the treatment. The selected isolates were cultured with C. acutatum to screen for the strain with excellent anti-fungal activities, among which an isolate FT333 showed more than 95% control efficacy against C. acutatum in vitro. The isolate was identified as Isaria javanica through its morphological characteristics and phylogenetic analysis of the ITS and β-tubulin nucleotide sequences. The Isaria javanica FT333 isolate could be used effectively for dual bio-control of thrips and anthracnose during red pepper cultivation.

실시간 분석을 위한 도커 컨테이너 기반의 딥러닝 모델 관리 시스템 설계 및 성능 비교

이모세(Mo-se Lee),강민수(Min-su Kang),김인호(In-ho Kim),김재헌(Jae-hun Kim) 한국통신학회 2021 韓國通信學會論文誌 Vol.46 No.2

구형 유도핀 (Bulb-tipped Guide Wire)과 K 강선을 이용한 파손된 금속정 제거술

이모세 ( Mo Ses Lee ),양규현 ( Kyu Hyun Yang ) 대한골절학회 2010 대한골절학회지 Vol.23 No.4

To report the unusual failure of proximal femoral nail antirotation (PFNA) at the level of lag screw hole and introduce a simple technique for removal of a broken intramedullary nail with a narrow hollow using a bulb-tipped guide wire and Kirschner wire.

TRAMP 트랜잭션 기반의 메타데이터 및 저널 복제 복구 기법

이모원(Mo-Weon Lee),원유집(You-Jip Won),김영진(Young-Jin Kim),김락기(Rak-Ki Kim),박재석(Jae-Suk Park),이주훤(Ju-Wheun Lee) 대한전자공학회 2006 대한전자공학회 학술대회 Vol.2006 No.11

In this paper, we propose metadata, journal replication and recovery technique to protect filesystem installed in digital appliance device from physical damage. Because hard disk can easily be damaged by user’s mistake in such environment, it may make filesystem can not be used anymore. So we propose transaction based metadata replication and recovery technique. In this algorithm, secondary metadata block updates its value with primary metadata as one transaction at same time. So if filesystem can’t read its metadata properly, it can be simply replaced by secondary meta data block and recovered by sector-remapping. To give more robustness, we also implement journal file replication and recovery technique. Lastly we proceed test of filesystem adjusted with TRAMP.

개방교합과 안면 비대칭을 보이는 골격성 II급 부정교합 환자의 비수술적 치료

이모현(Mo-Hyeon Lee) 대한치과교정학회 2024 대한치과교정학회 임상저널 Vol.14 No.1

In cases of patients with anterior open bite and facial asymmetry, particularly those with compromised temporomandibular joint (TMJ) stability, non-surgical camouflage treatments require a detailed and nuanced approach. TMJ instability, which often leads to mandibular deviation, complicates the functional and aesthetic correction. The initial evaluation of both functional asymmetry and skeletal asymmetry becomes essential. A critical step in managing these cases involves the use of a stabilization splint prior to orthodontic treatment. This approach aims to determine a reproducible and stable mandibular position, setting a foundation for subsequent corrective measures. This case report underscores the effectiveness of employing a mandibular stabilization splint in conjunction with intrusion of maxillary molars. This strategy targets the elimination of functional asymmetry and allows for a thorough re-evaluation of skeletal asymmetry. Despite initial presentation of facial asymmetry, a detailed assessment, including CBCT analysis, revealed that the skeletal asymmetry was not significant. This finding suggested that the observed facial asymmetry was largely attributable to functional discrepancies rather than skeletal imbalances. Focusing on correcting functional asymmetry, it was possible to significantly improve both the anterior open bite and facial asymmetry through non-surgical treatment. The treatment results highlight the potential of non-surgical treatment to effectively address complex malocclusions, offering patient significant improvements without the need for surgical intervention. (Clin J Korean Assoc Orthod 2024;14(1):9-20)

Comparison of Efficiency of Self-renewal and Differentiation Potential in Tendon-derived Mesenchymal Stem Cells Isolated by Magnetic-activated Cell Sorting Method or Colony Picking Method

이모세,최유림,윤동석,이진우,윤길성,최우진,한승환,Lee, Moses,Choi, Yoorim,Yoon, Dong Suk,Lee, Jin Woo,Yoon, Gil Sung,Choi, Woo Jin,Han, Seung Hwan The Korean Foot and Ankle Society 2014 대한족부족관절학회지 Vol.18 No.3

Purpose: The purpose of this study is to evaluate the efficacy of mesenchymal stem cell (MSC) isolation by the magnetic-activated cell sorting (MACS) method in tendon tissue-derived cells compared to the colony picking method for isolation of MSCs by picking colony-forming cells. Materials and Methods: Human tendon-derived cells were isolated by enzyme digestion using normal tendon tissues from three donors. We used the magnetic kit and well-known MSC markers (CD90 or CD105) to isolate MSCs in tendon-derived cells using MACS. Cloning cylinders were used to isolate colony-forming cells having MSC characteristics in tendon-derived cells. Colony-forming unit-fibroblast (CFU-F) assay was used to evaluate the self-renewal capacity of cells isolated using the colony picking method or MACS. For comparison of differentiation potentials into osteogenic or adipogenic lineage between two groups, alizarin red S and oil red O staining were performed at 14 days after induction of differentiation in vitro. Results: Flow cytometry results showed that early passage tendon-derived cells expressed CD44 in 99.13%, CD90 in 56.51%, and CD105 in 86.19%. In the CFU-F assay, CD90+ or CD105+ cells isolated with MACS showed larger colony formation in size than cells isolated using the colony picking method. We also observed that CD90+ or CD105+ cells were constantly differentiated into both osteogenic and adipogenic lineages in cells from all donors, whereas cells isolated using the colony picking method were heterogeneous in differentiation potentials to the osteogenic and adipogenic lineages. Conclusion: CD90+ or CD105+ cells isolated using MACS showed superior MSC characteristics in the self-renewal and multi-differentiation capacities compared with cells isolated using the colony picking method.