잔물땡땡이의 온도발육모형과 생물계절

윤성수,김명현,어진우,송영주,Yoon, Sung-Soo,Kim, Myung-Hyun,Eo, Jinu,Song, Young-Ju 한국환경생물학회 2020 환경생물 : 환경생물학회지 Vol.38 No.2

논 생태계 서식 생물을 장기적으로 모니터링하여 기후변화의 영향을 평가하기 위한 기초 연구로 잔물땡땡이의 발육단계별 온도발육모형을 선정하고 생태적 매개변수(유효적산온도, 발육한계온도, 발육최적온도, 발육최고온도)를 추정하였다. 선정된 온도발육모형을 이용하여 위도별 4 지역(철원, 당진, 부안, 해남)에서 발생하는 잔물땡땡이의 세대 수를 각 지역의 일 평균기온을 사용하여 예측하였다. 실험온도 구간(18~30℃)에서는 모든 성장단계에서, 발육속도가 온도에 따라 선형적으로 증가하였고 모형 사이의 적합성은 유의한 차이가 없었다. 하지만 발육최적온도와 달리 발육한계온도는 모형별로 상당한 차이를 보였다. 잔물땡땡이는 고위도인 철원에서 3.6 세대가 발생하지만 다른 지역에서는 4.3 세대가 발생하는 것으로 예측되었다. 본 연구의 결과는 기후변화에 따른 생물계절 변동 및 논 생태계 생물다양성 보전 연구의 기초자료로 활용될 것으로 보인다. Temperature-dependent development models for Hydrochara affinis were built to estimate the ecological parameters as fundamental research for monitoring the impact of climate change on rice paddy ecosystems in South Korea. The models predicted the number of lifecycles of H. affinis using the daily mean temperature data collected from four regions (Cheorwon, Dangjin, Buan, Haenam) in different latitudes. The developmental rate of each life stage linearly increased as the temperature rose from 18℃ to 30℃. The goodness-of-fit did not significantly differ between the models of each life stage. Unlike the optimal temperature, the estimated thermal limits of development were considerably different among the models. The number of generations of H. affinis was predicted to be 3.6 in a high-latitude region (Cheorwon), while the models predicted this species to have 4.3 generations in other regions. The results of this study can be useful to provide essential information for estimating climate change effects on lifecycle variations of H. affinis and studies on biodiversity conservation in rice fields.

설문 분석을 통한 농촌체험마을 방문객의 특성 -청원군 협력적관광모델개발의 사례로-

윤성수,리신호,박형수,Yoon, Seong-Soo,Rhee, Shin-Ho,Park, Hyung-Soo 한국농공학회 2008 한국농공학회논문집 Vol.50 No.6

The objectives of this study are investigate the satisfaction index and determined the characteristics of visitors. Also present the issues and direction for development of rural-experience village. This study area is seven villages of rural experience in Cheongwongun, Chungcheongbukdo. This place consists rural cooperative tourism model project that is pursued to Cooperative Tourism Model Project by the government. The projects are forming a network of towns and themes to be exhumed. The purpose of this project inner improves the ability of residents and external to contents diversification. This polling in the February-March 2008 was conducted between visitor 330 people. The question is personal information, satisfaction and rural tourism experience of detail as part of a total of 22.

고형암 환자의 수술 후 통증에 대한 침 치료 효과 : 체계적 문헌고찰 및 메타분석

윤성수,류한성,오혜경,이지영,윤성우,Yoon, Sung Soo,Ryu, Han Sung,Oh, Hye Kyung,Lee, Jee Young,Yoon, Seong Woo 대한암한의학회 2017 大韓癌韓醫學會誌 Vol.22 No.2

Objectives: Postoperative pain is one of postoperative complications in patients with solid tumor. This systematic review and meta-analysis were aimed to evaluate the efficacy of acupuncture for postoperative pain in solid tumor. Methods: We searched for randomized controlled trials (RCTs) using acupuncture for postoperative pain in adult patients with solid tumor up to September 2016. Acupuncture was defined as manual acupuncture, electroacupuncture and pharmacopuncture. The following databases were searched: PubMed, EMBASE, Cochrane Library, CNKI, CiNii, KoreaMed, Kmbase, KISS, NDSL, KISTI. The results of the studies were meta-analyzed and the risk of bias was assessed. Results: Five studies were included in this review. When acupuncture was compared with usual care, Prince-Henry pain scale score was significantly lower in acupuncture group (MD=-0.44, 95% CI: -0.62 to -0.26, P<0.001, $I^2=87%$) and 10 points pain score (including Numeric Rating Scale and Visual Analog Scale) was lower in acupuncture group but not significantly (MD=-1.00, 95% CI: -2.00 to -0.00, p=0.05). When acupuncture was compared with sham acupuncture, 10 points pain score was significantly lower in acupuncture group (MD=-0.39, 95% CI: -0.65 to -0.14, p=0.002, $I^2=0%$). Any serious adverse events were not reported. Conclusion: This review shows that acupuncture may be considered for postoperative pain in patients with solid tumor without serious adverse events. However, only a few studies were included in this study, further investigation is needed in this area.

농촌계획에 있어 다중회귀분석법에 의한 사업비 결정 - 경지정시사업비의 예 -

윤성수,이정재,조래청 ( Seong Soo Yoon,Jeong Jae Lee,Rae Cheung Cho ) 한국농촌계획학회 1996 농촌계획 Vol.2 No.2

전이암 환자의 예후 판단 인자로서 생체전기 임피던스 분석을 이용한 위상각의 역할

윤성수,윤성우,류한성,김은혜,이지영,Yoon, Sung-soo,Yoon, Seong-woo,Ryu, Han-sung,Kim, Eun-hye,Lee, Jee-young 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.4

Objectives: The aim of this study was to identify the validity of phase angle as a prognostic factor for survival in patients with metastatic cancer. Methods: Data of patients with metastatic cancer who visited the Korean medicine cancer center at Kyung Hee University Hospital in Gangdong from April 2016 to February 2018 were collected for this study. The values of phase angle (PhA) and blood hemoglobin (Hb), C-reactive protein (CRP), and serum albumin levels were also investigated by bioelectrical impedance analysis (BIA). Results: In total, 86 patients were analyzed. The cut-off value of the phase angle was determined as 5.0. Univariate and multivariate analysis revealed that phase angle (HR 3.15, 95% CI 1.79-5.54) and CRP (HR 2.15, 95% CI 1.24-3.73) predicted survival with statistical significance. The median overall survival of the low PhA group ($PhA{\leq}5.0$) was 1.8 months (95% CI 0.6-2.9 months) and 7.2 months (95% CI 5.2-9.2 months) in the high PhA group (PhA>5.0)(p<0.001). Conclusions: The phase angle could be an independent prognostic factor for patients with metastatic cancer. Further research is required to confirm these findings and their correlation with other indexes.

연속관입형 소형콘관입시험기에 대한 크기효과 및 현장적용

윤성수,김규선,이진형,신동현,Yoon, Sungsoo,Kim, Kyu-Sun,Lee, Jin Hyung,Shin, Dong-Hyun 대한토목학회 2013 대한토목학회논문집 Vol.33 No.6

콘관입시험은 현장조사 시험법으로 사용 빈도가 증가되고 있다. 그러나 콘관입시험은 콘크기와 용량 등에 따라 적용 가능한 현장조건이 제한되는 단점이 있다. 소형콘의 감소된 단면적은 시스템 용량을 증대시켜 적용성을 향상시킬 수 있으며, 코일식 롯드를 이용한 연속관입 시스템은 신속하고 경제적인 지반조사를 가능하게 한다. 본 연구에서는 국내 여러 현장에서 연속관입형 소형콘관입시험 시스템의 성능을 표준 콘관입시험 시스템과의 비교시험을 통하여 평가하였다. 소형콘관입시험 장비는 기존의 표준콘관입시험 장비와 비교하여 지반정수 도출 및 지반분류에 동일한 성능을 발휘하는 것을 확인하였으며, 장비의 기동성 및 적용대상 토질 확대 등의 장점을 나타내는 것으로 평가되었다. 크기효과 검증을 위한 현장시험 결과 기존 시험 방법에 비해 콘저항력의 경우는 약 10% 과대평가하는 것으로 나타났다. 차량 형태의 조사장비는 표층이 연약하거나 진입이 어려운 경우에는 조사의 한계가 있으므로, 궤도장치에 탑재된 연속관입형 소형콘관입시험 시스템으로 개선하여 적용성을 확대시켰다. 따라서 개선된 연속관입형 소형콘관입시험 시스템은 연약지반 심도탐지 및 흙분류시 경제적이고 신뢰성 높은 지반조사 방법으로 활용할 수 있다. Cone penetration tests (CPTs) have been increasingly used for site characterizations. However, the site investigations using CPTs are often limited due to soil conditions depending on the cone size and capacity of the CPT system. The small sectional area of a miniature cone improves the applicability of the CPT system due to the increased capacity of the CPT system. A continuous intrusion system using a coiled rod allows fast and cost effective site investigation. In this study, the performance of the continuous intrusion miniature cone penetration test (CIMCPT) system has been evaluated by comparison tests with the standard CPT system at several construction sites in Korea. The results show that the CIMCPT system has a same performance with the CPT system and has advantages on the mobility and applicability. According to field verification tests for scale effect evaluation, the cone tip resistance evaluated by CIMCPT overestimates by 10% comparing to standard CPTs. A crawler mounted with the CIMCPT system has been implemented to improve accessibility to soft ground, and has shown improvement over the truck type CIMCPT system. Therefore, the improved CIMCPT system can be utilized as a cost effective and highly reliable soil investigation methodology to detect the depth of soft ground and to evaluate soil classification.

전이 직장암 환자의 FOLFIRI 유발 설사에 위령탕 가감방 치험 1례

윤성수,김은혜,이지영,윤성우,Yoon, Sung Soo,Kim, Eun Hye,Lee, Jee Young,Yoon, Seong Woo 대한암한의학회 2018 大韓癌韓醫學會誌 Vol.23 No.1

Objectives : This study was aimed to describe a case of a patient with FOLFIRI-induced diarrhea, which was improved by treatment with Korean herbal medicine, modified Wiryeong-tang. Methods : The patient with metastatic rectal cancer recieved FOLFIRI plus bevacizumab as a palliative chemotherapy and showed repetitive diarrhea despite administration of loperamide, which was treated with modified Wiryeong-tang. To evaluate the effect of the treatment, the Bristol Stool Form Scale and bowel movement frequency were checked. Results : During the treatment, the stool form using Bristol Stool Form Scale was improved from diarrhea to normal stool, and the bowel movement frequency was decreased. Conclusions : The result suggest that modified Wiryeong-tang may be an effective treatment for FOLFIRI-induced diarrhea.

전이암 환자에서 단일기관 영양검색 도구의 예후 가치

윤성수,김민진,김은혜,이지영,윤성우,Yoon, Sung Soo,Kim, Min Jin,Kim, Eun Hye,Lee, Jee Young,Yoon, Seong Woo 대한암한의학회 2019 大韓癌韓醫學會誌 Vol.24 No.2

Objectives : We investigated whether a single center nutrition screening tool (Kyunghee Neo Nutrition Risk Screening, KNNRS) can predict survival in patients with metastatic cancer. Methods : We retrospectively reviewed data of inpatients with metastatic cancer from April 2016 to August 2019. Data on demographic and clinical parameters were collected from electronic medical records, and overall survival was estimated using the Kaplan-Meier method. Stepwise Cox regression analysis was used to determine factors associated with survival. Patients with a KNNRS score of 0 to 3 were classified as "no-risk", 4 to 10 as "low-risk", and 11 to 20 as "high-risk". Results : Total 105 patients were included in the study. According to nutritional screening at baseline, 25 patients (23.8%, median age 57.0) were classified as ""no risk"" group; 80 patients (76.2%, median age 68.5) as "low risk" group; No patients as "high risk" group. Predictors of survival were Eastern Cooperative Oncology Group Performance Status score of 3 or 4 (hazard ratio [HR] = 1.93; 95% confidence interval [CI] = 1.21-3.10), hemoglobin less than 10 g/dL (HR = 1.97; 95% CI = 1.25-3.10) and C-reactive protein more than 1.0 mg/dL (HR = 1.95; 95% CI = 1.21-3.13). Kaplan-Meier survival analysis showed significant differences in the survival between KNNRS groups: ""no risk"" group: 6.1 ± 1.4 months (95% CI = 3.37-8.83); ""low risk"" group: 3.4 ± 0.9 months (95% CI = 1.5-5.37). Conclusions : Nutritional status according to KNNRS wasn't significant predictor of survival for patients with metastatic cancer. Improvement of KNNRS score thresholds is needed.

자색 마령서 에탄올 추출물의 비만 및 고지혈증 억제효능

윤성수,이연희,이은옥,이효정,장유성,이근성,원숙현,임학태,김성훈,Yoon, Sung-Soo,Lee, Yun-Hee,Lee, Eun-Ok,Lee, Hyo-Jung,Jang, Yu-Sung,Lee, Keun-Sung,Won, Sook-Hyun,Lim, Hak-Tae,Kim, Sung-Hoon 대한동의생리학회 2007 동의생리병리학회지 Vol.21 No.3

This experimental study was performed to evaluate the effects of ehtanol extract of Purple Solanum tuberosum L(EPSTL) on obesity and hyperlipidemia in rats induced by high fat diet. Sprague-Dawley rats were divided into normal group, control group, EPSTL (100 mg/kg and 200 mg/kg) treated group. EPSTL was orally administered to the obese rats by high fat diet for 6 weeks. The effect of EPSTL on obesity and hyperlipidemia were examined in vitro and in vivo as follows : EPSTL effectively inhibited the differentiation of 3T3-L1 adipocytes in a concentration dependent manner. EPSTL significantly lowered body weight of rats fe high fat diet for 6 weeks from 4 weeks treatment compared with untreated control. EPSTL significantly reduced the weight of retroperitoneal fat only at 100 mg/kg and epididymal fat pad in rats fed high fat diet for 4 weeks at 100 and 200 mg/kg. EPSTL significantly reduced the level of triglyceride at 200 mg/kg, while EPSTL tended to lower the levels of total lipid and phospholipid in rats fed high fat diet for 4 weeks with no significance. EPSTL significantly attenuated the level of total cholesterol, LDL and atherosclerosis index (Al) as well as increased the level of HDL at 200 mg/kg. EPSTL significantly reduced the levels of total lipid and triglyceride of hepatic tissues in rats fed high fat diet for 4 weeks at 200 mg/kg. EPSTL significantly lowered the level of insulin, while it did not affect leptin compared with untreated control. Taken together, these results suggest that EPSTL can be used for the treatment or prevention of hyperlipidemia and obesity.

다변량분석법을 이용한 충청북도 읍면단위 농촌계획 수립을 위한 지역유형구분 분석

윤성수 ( Seong Soo Yoon ),주호길 ( Ho Gil Joo ) 한국농촌계획학회 2005 농촌계획 Vol.11 No.2