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소아 아토피피부염에서 아토피성과 비아토피성의 중증도와 검사소견의 비교
신정은,전유훈,양현종,편복양 대한 소아알레르기 호흡기학회 2008 Allergy Asthma & Respiratory Disease Vol.18 No.3
Purpose:We aim to compare clinical severity of atopic and non-atopic eczema in children and examine the relationship between total-IgE, eosinophil counts, Eosinophil, Eosinophil cationic protein (ECP) and clinical severity of atopic dermatitis (AD). Methods:A total of 271 children diagnosed with AD at the Pediatric Allergy Respiratory Center in Soonchunhyang University Hospital from October 2005 to March 2008 were enrolled for this study and divided into 2 groups: atopic and non-atopic eczema. Serum concentrations of total- and specific-IgE, eosinophil counts and ECP were measured. Allergy skin tests were also performed and the SCORAD index was used to evaluate clinical severity. Comparisons the SCORAD index and serum total-IgE, eosinophil count and ECP between the 2 groups were made. Results:Of the 271 patients, 162 (59.8%) were included in the atopic eczema group, while 109 (40.2%) were included in the non-atopic group according to the laboratory results. Serum total- IgE, eosinophil counts, ECP, the SCORAD index and the frequency of a family history of eczema were relatively higher in the atopic group. In the atopic group, serum total-IgE, eosinophil counts and ECP each had a statistically significant correlation with the SCORAD index with eosinophil counts showing the highest correlation. However, only eosinophil counts had a statistically significant correlation with the SCORAD index in the non-atopic group. Conclusion:Serum total-IgE, eosinophil counts, and ECP can be used as markers for clinical severity in patients with atopic eczema, while eosinophil counts be used as marker for clinical severity in those with non-atopic eczema. Purpose:We aim to compare clinical severity of atopic and non-atopic eczema in children and examine the relationship between total-IgE, eosinophil counts, Eosinophil, Eosinophil cationic protein (ECP) and clinical severity of atopic dermatitis (AD). Methods:A total of 271 children diagnosed with AD at the Pediatric Allergy Respiratory Center in Soonchunhyang University Hospital from October 2005 to March 2008 were enrolled for this study and divided into 2 groups: atopic and non-atopic eczema. Serum concentrations of total- and specific-IgE, eosinophil counts and ECP were measured. Allergy skin tests were also performed and the SCORAD index was used to evaluate clinical severity. Comparisons the SCORAD index and serum total-IgE, eosinophil count and ECP between the 2 groups were made. Results:Of the 271 patients, 162 (59.8%) were included in the atopic eczema group, while 109 (40.2%) were included in the non-atopic group according to the laboratory results. Serum total- IgE, eosinophil counts, ECP, the SCORAD index and the frequency of a family history of eczema were relatively higher in the atopic group. In the atopic group, serum total-IgE, eosinophil counts and ECP each had a statistically significant correlation with the SCORAD index with eosinophil counts showing the highest correlation. However, only eosinophil counts had a statistically significant correlation with the SCORAD index in the non-atopic group. Conclusion:Serum total-IgE, eosinophil counts, and ECP can be used as markers for clinical severity in patients with atopic eczema, while eosinophil counts be used as marker for clinical severity in those with non-atopic eczema.
소아 아토피피부염에서 아토피성과 비아토피성의 중증도와 검사소견의 비교
신정은 ( Jung Eun Shin ),전유훈 ( You Hoon Jeon ),양현종 ( Hyeon Jong Yang ),편복양 ( Bok Yang Pyun ) 대한소아알레르기호흡기학회(구 대한소아알레르기 및 호흡기학회) 2008 소아알레르기 및 호흡기학회지 Vol.18 No.3
목적: 아토피피부염의 발생기전에 있어 IgE와 호산구 및 ECP가 아토피피부염의 발생기전에 중요한 역할을 하리라 생각되고 있으나 이러한 검사결과와 임상적 중증도와의 상관관계에 대해서는 논란이 있다. 본 저자들은 아토피피부염 소아에서 아토피성과 비아토피성의 임상양상을 비교해보고 총 혈청 IgE, 혈중 호산구수, ECP 농도 등의 실험실 검사소견과 아토피피부염의 임상적 중증도의 상관관계를 밝혀 이의 임상적 유용성을 알아보고자 하였다. 방법: 2005년 10월부터 2008년 3월까지 순천향대학교병원 소아알레르기 호흡기센터에서 아토피피부염으로 진단받은 환아 271명을 대상으로 하였고 대상 환아에서 혈청 총 IgE치와 원인 항원 특이 IgE치, 말초 혈액 내 총 호산구수, ECP를 측정하였으며, 피부단자 시험을 시행하였다. SCORAD 점수를 통해 임상적 중증도를 반영하는 지표로 사용하였으며 천식과 알레르기비염의 동반여부와 알레르기 질환에 대한 가족력을 조사했다. 전체 환아는 특이 IgE가 한 가지 이상 양성이거나 피부단자시험에서 양성을 보인 아토피군과 특이 IgE가 모두 음성이며 피부 단자시험에서도 음성을 보인 비아토피군으로 분류하여 두 군에서 임상적 중증도를 반영하는 SCORAD 점수와 혈청 총 IgE치, 말초 혈액 내 호산구수, ECP의 상관관계를 조사하였다. 결과: 총 271명의 대상 환아중 아토피군은 162명, 비아토피군은 109명이었다. 총 IgE치, 말초 혈액내 호산구수, ECP, 아토피피부염의 가족력이 아토피군에서 비아토피군보다 더 높은 수치를 보였으며, 아토피군에서 SCORAD 점수가 더 높아 임상적 중증도가 더 높은 것으로 나타났다. 아토피군에서는 혈청 총 IgE치, 말초 혈액 내 호산구수, ECP 모두 SCORAD 점수와 통계적으로 유의한 상관관계를 보였으며, 이중 말초 혈액 내 호산구수의 상관계수가 가장 높았으며, 비아토피군에서는 말초 혈액내 호산구수만 SCORAD 점수와 통계적으로 유의한 상관관계를 보였으며 혈청 총 IgE치와 ECP는 상관관계를 보이지 않았다. 결론: 혈청 총 IgE치, 말초혈액 내 호산구수, ECP농도를 아토피성 아토피피부염 환아에서 중증도의 평가 지표로 사용할 수 있으며 호산구수는 비아토피성 환아에서도 중증도 판정에 역할을 할 수 있겠다. Purpose: We aim to compare clinical severity of atopic and non-atopic eczema in children and examine the relationship between total-IgE, eosinophil counts, Eosinophil, Eosinophil cationic protein (ECP) and clinical severity of atopic dermatitis (AD). Methods: A total of 271 children diagnosed with AD at the Pediatric Allergy Respiratory Center in Soonchunhyang University Hospital from October 2005 to March 2008 were enrolled for this study and divided into 2 groups: atopic and non-atopic eczema. Serum concentrations of total- and specific-IgE, eosinophil counts and ECP were measured. Allergy skin tests were also performed and the SCORAD index was used to evaluate clinical severity. Comparisons the SCORAD index and serum total-IgE, eosinophil count and ECP between the 2 groups were made. Results: Of the 271 patients, 162 (59.8%) were included in the atopic eczema group, while 109 (40.2%) were included in the non-atopic group according to the laboratory results. Serum total-IgE, eosinophil counts, ECP, the SCORAD index and the frequency of a family history of eczema were relatively higher in the atopic group. In the atopic group, serum total-IgE, eosinophil counts and ECP each had a statistically significant correlation with the SCORAD index with eosinophil counts showing the highest correlation. However, only eosinophil counts had a statistically significant correlation with the SCORAD index in the non-atopic group. Conclusion: Serum total-IgE, eosinophil counts, and ECP can be used as markers for clinical severity in patients with atopic eczema, while eosinophil counts be used as marker for clinical severity in those with non-atopic eczema. [Pediatr Allergy Respir Dis(Korea) 2008;18:219-227]
백영흠,양신정 대구대학교 과학기술연구소 1998 科學技術硏究 Vol.5 No.3
This study has researched on the utilization of living space through interview with resider in the same family OKGOL village. OKGOL is located Doon San Dong Dong Gu, Tae-Gu and constitute of Kyoung-Ju Choi's The purpose of this research was considered to subsist and to use of living space through food, clothing and shelter and entertainment of the OKGOL village. As the ivsult of this study, the space of men's and women', is separated in the living space of the same family OKGOL village. This separation is due to Koreaan traditional consideration. Speciall, This village has independent storage which is called Duy-Ju in each of houses. And dwellings' pattern is following traditional method.
최우회,박웅양,황방연,오갑진,강신정,이경순,노재섭,Choi, Woo-Hoi,Park, Woong-Yang,Hwang, Bang-Yeon,Oh, Gap-Jin,Kang, Shin-Jung,Lee, Kyong-Soon,Ro, Jai-Seup 한국생약학회 1998 생약학회지 Vol.29 No.3
Eight compounds were isolated from the stem bark of Cornus walteri. On the basis of chemical and spectroscopic evidences, the structures of these compounds were identified as gallic acid, (+)-gallocatechin, (+)-catechin, quercetin, quercitrin, rutin, isoquercitrin and hyperoside respectively.
안영진,이승호,강신정,황방연,박웅양,안병태,노재섭,이경순 영남대학교 약품개발연구소 1996 영남대학교 약품개발연구소 연구업적집 Vol.6 No.-
A chemical examination of the phenolic compounds in the leaves of Sapium japonicum (Euphorbiaceae) has led to the isolation of eleven phenolic compounds. containing five hydrolysable tannins and six flavonoids. On the basis of chemical and spectroscopic evidences, the structures of these compounds were confirmed to be galic acid(1), 5-O-caffeoyl quinic acid(2), 1-O-galloyl-3, 6-(R)-HHDP-β-n-glucose(coriiagin)(3), 1-O-galloyl-2.4-(R)-DHHDP-βn-glucose (furosin)(4), 1-O-galloyl-2.4-(R)-DHHDP-3.6-(R)-HHDP-β-m-glucose(geraniin)(5), astragalin(6), trifolin(7), afzelin(8), quercetin(9), isoquercitrin(10) and rutin(11). Among them geraniin was the main component.