감압밸브 진단 및 설계 연구

심현준 한국유체기계학회 2022 한국유체기계학회 학술대회 논문집 Vol.2022 No.11

소음성 난청

심현준 한양대학교 의과대학 2015 Hanyang Medical Reviews Vol.35 No.2

Noise-induced hearing loss (NIHL) is the second most common cause of permanent hearing impairment after age-related hearing loss. NIHL is influenced by environmental and genetic factors and the effects of noise can be exacerbated by the administration of ototoxic drugs or exposure to chemicals. The pathophysiology of NIHL is classified as either mechanical injury or metabolic (or biochemical) injury. Exposure of cochleae to intense sounds has been found to disrupt the stereocilia on the hair cells by separating the tip links and to depolymerize actin filaments, resulting in a disturbance in signal transduction. Major mechanisms of metabolic injuries include accumulation of reactive oxygen species enhanced by oxidative stress, cochlear ischemia followed by reperfusion injury, and excitotoxicity to auditory neuron induced by excessive release of the cochlear afferent neurotransmitter, glutamate. Many studies involving therapeutic or preventive trial with antioxidants, JNK inhibitors, and NMDA antagonists have shown partial effectiveness. However, protection from noise before cochlear injury occurs is very important because damaged hair cells and auditory neurons in the mammalian cochleae are unable to regenerate.

실사 기반 VR 콘텐츠의 감성 반응 연구: 360 제품 이미지를 중심으로

심현준,노연숙 한국감성과학회 2020 감성과학 Vol.23 No.2

Given the development of information technology, various methods for efficient information delivery have been constructed as the method of delivering product information moves from offline and 2D to online and 3D. These attempts not only are about delivering product information in an online space where no real product exists but also play a crucial role in diversifying and revitalizing online shopping by providing virtual experiences to consumers. 360 product image is a photorealistic VR that allows a subject to be rotated and photographed to view objects in three dimensions. 360 product image has also attracted considerable attention considering that it can deliver richer information about an object compared with the existing still image photography. 360 product image is influenced by divergent production factors, and accordingly, a difference emerges in the responses of users. However, as the history of technology is short, related research is also insufficient. Therefore, this study aimed to grasp the responses of users, which vary depending on the type of products and the number of source images in the 360 product image process. To this end, a representative product among the product groups that can be frequently found in online shopping malls was selected to produce a 360 product image and experiment with 75 users. The emotional responses to the 360 product image were analyzed through an experimental questionnaire to which the semantic classification method was applied. The results of this study could be used as basic data to understand and grasp the sensitivity of consumers to 360 product image. 정보 기술 발전으로 인하여 제품 정보를 전달하는 방식이 오프라인과 2D중심에서 온라인과 3D로 이동하면서 효율적 인 정보 전달을 위한 다양한 시도가 이루어지고 있다. 이러한 시도는 실물이 부재된 온라인 공간에서 단순히 제품의 정보를 전달하는 것에 그치지 않고 소비자에게 가상의 체험을 제공하면서 온라인 쇼핑의 다변화 및 활성화에 중요한 역할을 하고 있다. 360 제품 이미지는 피사체를 회전시켜 촬영하여 대상을 다양한 시점에서 입체적으로 볼 수 있는 실사 기반의 VR이다. 360 제품 이미지는 기존의 정지 이미지와 비교하여 대상물에 대해 풍부한 정보를 전달할 수 있다는 측면에서 주목받고 있다. 360 제품 이미지는 다양한 제작 요인에 의해 영향을 받으며, 이에 따라 이용자의반응에 차이가 있으나 기술의 역사가 짧은 만큼 관련 연구 또한 미비하다. 따라서 본 연구에서는 360 제품 이미지의 제품의 형태와 소스 이미지의 수에 따라 변하는 이용자의 반응을 파악하고자 하였다. 이를 위해 온라인 쇼핑몰에서 많이 접할 수 있는 상품군 중 대표적인 제품들을 선정하여 360 제품 이미지를 제작하고 75인의 이용자를 대상으로 실험을 진행하였으며, 의미분별법을 적용한 실험 설문을 통해 360 제품 이미지에 대한 감성 반응을 분석하였다. 본 연구의 결과는 360 제품 이미지에 대한 수용자의 감성을 이해하고 파악하는데 기초 자료로 활용될 수 있을 것이다.

이미지 기반 제품 유사도 추출 및 패션 상품 배분 최적화

심현준,성신웅,백현석,장영재 한국경영과학회 2017 한국경영과학회 학술대회논문집 Vol.2017 No.4

360 제품 사진의 특성과 내적혁신성이 지속이용의도에 미치는 영향에 관한 연구

심현준,이종윤,김헌 한국콘텐츠학회 2020 한국콘텐츠학회논문지 Vol.20 No.6

360 product photography is one of the realistic media technologies that can observe subjects from various angles as one of the real-world VR production methods. This study examined the effect of 360 product photography on the intention to Continuous Use through the technology acceptance model. The results of the online survey showed that informative, which is the characteristic of 360 product photography, affects both ease of use and perceived usefulness, while reliability and entertainingness affect only perceived usefulness. Internal innovation had an impact on perceived ease, but not on perceived usability. Ease of use, both mediators, had a positive effect on sustained use intention. These findings can be used as a reference for various studies in the field of 360 product photography which is still insufficient. In addition, it can provide strategic implications for the production direction of 360 product photos. 360 제품 사진은 실사를 기반으로 하는 VR 제작 방식의 하나로 피사체를 다각도에서 관찰할 수 있는 실감미디어 기술 중 하나이다. 본 연구는 기술수용모델을 통하여 360 제품 사진의 특성과 내적혁신성이 지속이용의도에 미치는 효과를 살펴보았다. 온라인 설문조사 결과, 360 제품 사진의 특성인 정보성은 지각된 용이성과 지각된 유용성에 모두 영향을 미치고 있는 반면, 신뢰성과 오락성은 지각된 유용성에만 영향을 미치고 있는 것으로 나타났다. 내적혁신성은 지각된 용이성에 영향을 미치고 있었지만 지각된 유용성에는 영향을 미치지 않았다. 매개변인인 지각된 용이성과 지각된 유용성은 모두 지속이용의도에 정적인 영향을 미치는 것으로 나타났다. 본 연구의 결과는 아직까지 미흡한 360 제품 사진 관련 분야에 다양한 연구를 위한 참고자료로 활용될 수 있을 것이다. 더불어, 360 제품 사진의 실무 제작에 전략적인 시사점을 제공할 수 있다.

Feasibility and Safety of Transcutaneous VagusNerve Stimulation Paired with Notched Music Therapyfor the Treatment of Chronic Tinnitus

심현준,곽민영,안용휘,김동현,김윤진,김효정 대한청각학회 2015 Journal of Audiology & Otology Vol.19 No.3

Background and Objectives: A recent study demonstrated that tinnitus could be eliminated by vagus nerve stimulation (VNS) paired with notched sounds in a rat tinnitus model. The aims of this clinical study were to investigate the effects and safety of transcutaneous VNS (tVNS) by patch-type electrode paired with notched music for treating chronic tinnitus. Subjects and Methods: Thirty patients with refractory chronic tinnitus for >12 months were included in this study. A patch-type electrode was attached to the auricular concha of the patient's left ear and tVNS was performed for 30 min (pulse rate 25 Hz, pulse width 200 μs, and amplitude 1-10 mA) using a transcutaneous electric nerve stimulation eco2. During tVNS, the patients listened to notched music cleared of the frequency spectrum corresponding to the tinnitus with a 0.5 octave notch width. Results: After 10 treatment sessions, 15/30 patients (50%) reported symptom relief in terms of a global improvement questionnaire. The mean tinnitus loudness (10-point scale) and the mean tinnitus awareness score (%) improved significantly from 6.32±2.06 to 5.16±1.52 and from 82.40±24.37% to 65.60±28.15%, respectively (both p<0.05). None of the patients had any specific side effects, such as changes in heart rate or blood pressure. Conclusions: This study has demonstrated the feasibility and safety of tVNS paired with notched music therapy in patients with chronic tinnitus, with the use of a pad-type electrode attached to the auricular concha. Background and Objectives: A recent study demonstrated that tinnitus could be eliminated by vagus nerve stimulation (VNS) paired with notched sounds in a rat tinnitus model. The aims of this clinical study were to investigate the effects and safety of transcutaneous VNS (tVNS) by patch-type electrode paired with notched music for treating chronic tinnitus. Subjects and Methods: Thirty patients with refractory chronic tinnitus for >12 months were included in this study. A patch-type electrode was attached to the auricular concha of the patient's left ear and tVNS was performed for 30 min (pulse rate 25 Hz, pulse width 200 μs, and amplitude 1-10 mA) using a transcutaneous electric nerve stimulation eco2. During tVNS, the patients listened to notched music cleared of the frequency spectrum corresponding to the tinnitus with a 0.5 octave notch width. Results: After 10 treatment sessions, 15/30 patients (50%) reported symptom relief in terms of a global improvement questionnaire. The mean tinnitus loudness (10-point scale) and the mean tinnitus awareness score (%) improved significantly from 6.32±2.06 to 5.16±1.52 and from 82.40±24.37% to 65.60±28.15%, respectively (both p<0.05). None of the patients had any specific side effects, such as changes in heart rate or blood pressure. Conclusions: This study has demonstrated the feasibility and safety of tVNS paired with notched music therapy in patients with chronic tinnitus, with the use of a pad-type electrode attached to the auricular concha.

RCP 8.5 극한기온 타당성 평가

심현준,안미진,김상단 한국방재학회 2014 한국방재학회논문집 Vol.14 No.3

RCPs have been proposed in IPCC 5th report. Based on it, KMA has developed and provided future climate information to meetKorea. This study investigates whether KMA RCP 8.5 data can be appropriate in applying to analyze future extreme air temperature. For this purpose, first the reproducibility of past extreme air temperature is evaluated by comparing RCP 8.5 data with observed data. Based on this evaluation, simulated future extreme air temperature is assessed. As a result, KMA RCP 8.5 is thought to be appropriatein applying to analyze future normal air temperature, but to be necessary to revise in applying to analyze future extreme air temperature. IPCC 5차 기후평가 보고서에서 새로운 온실가스 시나리오인 RCPs(Representative Concentration Pathways)가 제시되었으며, 이를 바탕으로 우리나라 기상청에서도 우리나라에 맞는 미래기후정보를 개발하여 제공하고 있다. 이에 본 연구에서는 기상청에서 제공하고있는 RCP 8.5 자료가 미래극한기온 분석에 타당한지에 대하여 살펴보았다. 이를 위하여 먼저, RCP 8.5 자료와 관측 자료의 비교를 하여 과거극한기온정보를 정확히 반영하는지에 대해서 평가하고 이를 바탕으로 미래극한기온 자료를 평가하였다. 적용결과 기상청 RCP8.5 자료는 평균적인 기온에 대해서는 적절하게 적용될 수 있으나, 극한기온에 대해서는 수정보완이 필요한 것으로 나타났다.

측두골 전산화 단층촬영의 정량적 측정을 이용한 내이 기형의 진단

심현준,신정은,정종우,이광선 대한이비인후과학회 2006 대한이비인후과학회지 두경부외과학 Vol.49 No.7

Background and Objectives:The objectives of this study were to achieve the normative measurements of inner ear structures on temporal bone computed tomography (TBCT) and, by using these data, diagnose the malformations of severe to profound sensorineural hearing loss (SNHL) ear accurately. Subjects and Method:For the normative data of the inner ear structures, the TBCT of 60 patients (120 ears) with normal bone-conduction threshold (<15 dB) were used and the data were applied to 570 ears of 285 cochlear implantees with severe to profound SNHL. Six identifiable inner ear structures (cochlea, vestibule, superior semicircular canal, lateral semicircular canal, posterior semicircular canal, and internal auditory canal) were measured in numerically designated areas by picture archiving and communications system. The inner ear anomalies were defined when the structures presented visually obvious malformations or when the measurements deviated 2 standard deviations (SD) from the means in the normative data. Results:We achieved the mean and SD values from the normal bone-conduction group. A total of 293 anomalies were detected in 127 of the 570 (22.3%) profound SNHL ears. An enlarged vestibular aqueduct was the most common individual anomaly (49 cases), followed by vestibular enlargement (38 cases), other semicircular canal dysplasia (37 cases), and shortened cochlea (34 cases). Conclusion:We suggested a measurement technique for the inner ear structures using TBCT and derived normative measurements helpful for diagnosing inner ear anomalies. Quantitative measurements of the cochlea may improve the detection of cochlear hypoplasia and SCC dysplasia from relying on simple visual inspection. (KoreanJ Otolaryngol 2006;49:688-94)

패션 산업의 산업 공학 방법론 활용 사례연구

심현준,백현석,성신웅,장영재 대한산업공학회 2016 대한산업공학회 추계학술대회논문집 Vol.2016 No.11

Intratympanic Steroid Injection in Tinnitus Management

심현준 한양대학교 의과대학 2016 Hanyang Medical Reviews Vol.36 No.2

Intratympanic (IT) steroid injection has been used increasingly in various inner ear diseases instead of systemic steroid, because of the higher concentration of the drug into the target organ and the lower risk of the systemic side effect. Although there were several trials applying IT steroid injection on tinnitus, most of them failed to demonstrate its therapeutic effect more than controls. However, a study has shown a meaningful outcome when the therapeutic target is limited to acute tinnitus developed within 3 months. Although IT steroid injection treatment in tinnitus requires more evidence, when the therapeutic target is limited to the acute phase, IT steroid injection could be a treatment option for tinnitus. Early intervention, asymmetric hearing loss and unilateral tinnitus seem to be favorable factors for outcome of IT steroid injection.