Apolipoprotein E 다형성에 따른 사업장 근로자의 혈중 지질농도, 영양소 섭취 및 건강관련 생활습관

박유경,조상운,강지연,백윤미,성숙희,최태인 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.5

The purpose of this study was to investigate the association among nutrient intakes and health-related lifestyles with cardiovascular disease risk assessed by blood lipid profile according to Apolipoprotein E genotypes. Middle-aged industrial male workers who had completed their annual medical examination were recruited and data of 675 subjects who finished the nutrient survey were used in the analysis. Anthropometric parameters, dietary assessment (FFQ), health-related lifestyles and blood profiles were used for statistical analyses. Apo E genotype groups were classified into the following three genotypes: Apo E2 group (including E2/E2, E2/E3, E2/E4), Apo E3 group (including E3/E3), Apo E4 group (including E3/E4, E4/E4). The frequency of Apo E2, E3, and E4 allele were 13.3%, 75.0% and 11.7% respectively. There were no significant differences in the anthropometric parameters depending on different Apo E genotypes. Also, no significant differences in the nutrient intakes were found according to the genotype groups. The nutrient intakes of all subjects were similar to or higher than the level of KDRIs (Dietary Reference Intakes For Koreans) except for intakes of calcium (67.44% of KDRIs), vitamin A (73.83% of KDRIs) and vitamin B2 (78.02% of KDRIs). Also, there were no significant differences of health-related lifestyles according to Apo E genotype groups. As for the lipid profiles, Apo E4 group had significantly higher total and LDL-cholesterol concentrations than the Apo E2 group (p < 0.05). We confirmed that plasma total and LDL-cholesterol concentrations were greatly influenced by Apo E genotypes. However, nutrient intakes and health-related lifestyles were not associated with Apo E genotypes.

사회문제 중심의 지역화 교재구성의 실제 : 울산지역을 중심으로 in the case of Ulsan

이기복,성숙희 부산교육대학교 교육대학원 2001 논문집 Vol.3 No.-

The goal of this study is to introduce regional social problems that might embody the essence of region in the social curriculum at elementary school social studies, to constitute learning material in an integrated way, and to embody a proper teaching model. In order to reach this goal, first, this study provides a standard that refers to general theoretical research about region and social problems and principles and method in text composition. Second, this study abstracts social problems relating to the Ulsan region and classifies their features for the development of integrated teaching material for inter-studies. Third, this study embodies the teaching-learning model of the social studies curriculum at the heart of the content of the text and tries to apply it to the school classroom environment. Especially, in order to make teaching material that addresses key social problems of the region, this study divides social problems in the Ulsan region into problems of social organization, social disorganization, and deviation, and divides them again into the following problem types: economic, regional gap, city, environmental, home, and crime. Furthermore, it suggests a procedure for text composition and clearly shows, as related constituents, the key idea, the goals, the teaching-learning process, and the assignment. It takes into account Learner's development of social consciousness and experiential Level as much as possible.

건강한 여성 근로자에서 Apolipoprotein E와 혈중 지질 농도와의 관련성

문기은,성숙희,장윤균,박일근,백윤미,김수근,최태인,진영우,Moon, Gi-Eun,Sung, Sook-Hee,Chang, Youn-Koun,Park, Il-Keun,Paek, Yun-Mi,Kim, Soo-Geun,Choi, Tae-In,Jin, Young-Woo 대한예방의학회 2010 예방의학회지 Vol.43 No.3

Objectives: Plasma lipid profiles and Apolipoprotein E (ApoE) are established risk factors for cardiovascular disease (CVD). The knowledge of lipid profile may estimate the potential victims of cardiovascular disease before its initiation and progression and offers the opportunity for primary prevention. The most common ApoE polymorphism has been found to influence plasma lipid concentrations and its correlation with CVD has been extensively investigated in the last decade. Methods: The ApoE polymorphism and its influence on plasma lipid were investigated in healthy woman workers. The information on confounding factors was obtained through a self-administered questionnaire and ApoE polymorphism was investigated using PCR. Results: The relative frequencies of alleles E2, E3 and E4 for the study population (n = 305) were 0.127, 0.750 and 0.121, respectively. ApoE polymorphism was associated with variations in plasma HDL-cholesterol lipid profile. In order to estimate the independent effects of alleles E2 and E4, as compared with E3, on lipid profile, multiple regression was performed after adjustment for confounding variables such as age, BMI, blood pressure, education status, insulin, fasting glucose, HOMA-IR, menopause. ApoE2 had a negative association with HDL cholesterol and ApoE4 had a positive association with LDL cholesterol. Conclusions: This study identified that the ApoE and CVD risk factors contribute to the lipid profiles, similar to other studies. The analysis including dietary intake and other gene in further studies may help to identify clear effects on lipid profiles as risk factor for CVD.

40ㆍ50대 일부 남성근로자의 골감소증 및 골다공증 유병실태와 위험요인

장윤균,서현주,진영우,정미선,성숙희,박두용,김종순,김수근 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

목적: 최근 국내에서도 골다공증과 관련된 생활양식의 규명에 관한 연구가 이루어지고 있으나, 아직까지 남성 골다공증에 대한 연구가 활발하게 이루어지지 않아 40, 50대 남성근로자를 대상으로 유병률을 파악하고, 골감소증 및 골다공증 관련 위험요인을 확인하고자 하였다. 방법: 원자력발전소에 근무하는 40, 50대 남성 근로자 2,073명을 대상으로 2004년 3월~7월 기간동안 생활습관을 파악하기 위하여 자기기입식 전산입력 방식으로 최종학력, 흡연여부, 음주여부, 신체활동 횟수를 조사하였고, 골밀도검사, 체성분검사(체지방률, 허리-엉덩이둘레비), 신체계측(신장, 체중)을 시행하였고, 골밀도 검사는 Osteosys사의 EXE-3000을 이용하여 종골부위를 측정하였고, 체지방률, 허리-엉덩이 둘레비는 Biospace사의 Inbody 3.0을 이용하여 측정하였다. 통계분석은 골감소증 및 골다공증의 관련요인을 분석하기 위해 다중로지스틱회귀분석을 시행하였다. 결과: 연구대상자의 골감소증 및 골다공증 유병률은 22.8%와 3.0%이었으며, 골감소증 및 골다공증의 관련요인으로는 연령이 증가할수록, 흡연자이거나 과거흡연자일 경우, 체질량지수가 25 kg/m^(2) 미만일 경우, 30분 이상 신체활동 횟수가 주 3회 미만일 경우가 유의한 연관성이 있었다. 결론: 성인 남성 40, 50대의 골감소증 및 골다공증의 유병률이 높은 편이었으며, 골감소증 및 골다공증으로 이환을 예방하기 위하여 금연, 활발한 신체활동을 촉진하여 골밀도를 개선시키는 생활습관으로의 변화를 권고해야 할 것이다. Objective: This study was conducted to investigate the prevalence and risk factors of osteopenia and osteoporosis in 40-59 year-old male workers working at nuclear power plants. Methods: Bone density, body composition, and anthropometry data were analyzed for 2,073 subjects were carried out from March 2004 to July, 2004. Educational level, smoking status, drinking status and frequency of physical activity were investigated by self-reported questionnaires through internet to identify lifestyles related to bone mass density. Bone mass density was measured by EXE-3000 of Osteosys Co. And body fat percentage, and waist-to-hip ratio by inbody 3.0 of Biospace Co. Results: The prevalence of ostepeniaosteopenia and osteoporosis was 22.8% and 3.0%, respectively. According to multinominal multinomial logistic regression analysis, age, smoking status (current smoker and former smoker), low body mass index (< 25kg/m^(2)), and frequency of physical activity were significantly associated with osteopenia and osteoporosis. Conclusions: The prevalence of ostcopenia and osteoporosis wasseemed high for the, when it was inferred from subjects' age compared to the results of previous studies. The This study results suggeststhat it is necessary for 40-59 year-old male workers to stop smoking, and exercise regularly in order to prevent osteopenia and osteoporosis.

온라인 건강교육프로그램이 남성근로자의 대사증후군 위험요인 및 영양소 섭취에 미치는 영향

강지연(Kang Ji-Yeon),조상운(Cho Sang-Woon),이지영(Lee Ji-Young),성숙희(Sung Sook-Hee),박유경(Park Yoo-Kyoung),백윤미(Paek Yun-Mi),최태인(Choi Tae-In) 韓國營養學會 2010 Journal of Nutrition and Health Vol.43 No.1

Worksite health promotion programs have been associated with reductions in health risks but are labor-intensive and costly to implement. Therefore, innovative strategies to provide a cost-effective approach to health education program are needed. The purpose of this study was to investigate the effects of a worksite on-line health education program by email on metabolic syndrome risk factors and dietary intakes in male workers with metabolic syndrome. Anthropometric and biochemical parameters were measured and the nutrient intakes were assessed through FFQ. The diagnosis of metabolic syndrome was adapted from NCEP-ATP Ⅲ with blood pressure, fasting blood glucose, triglyceride, HDL cholesterol, and Asia-Pacific definition with waist circumference. The education group consisted of 212 male workers and the non-education group of 236 age-matched male workers. The on-line health education program provided 10 sessions by e-mail. After a worksite on-line health education program, systolic blood pressure (p < 0.001), diastolic blood pressure (p < 0.001) and fasting blood glucose (p < 0.001) were significantly decreased and HDL cholesterol (p < 0.001) was significantly increased in the education group. Intakes of total energy (p < 0.05), carbohydrate (p < 0.05), sodium (p < 0.05) were significantly decreased in the education group, but there were no significant differences in dietary intakes in the non-education group after a worksite on-line health education program. The results indicate that online health education program by e-mail is effective for improving metabolic syndrome risk factors and dietary intakes in male workers and show potential for use in the working setting.

실천지침 이행률에 따른 대사증후군 중재 효과 비교

남경희(Nam, Kyung-Hui),강지연(Kang, Ji-Yeon),이연주(Lee, Yeon-Ju),성숙희(Sung, Sook-HeeChang),장윤균(Youn-Koun),이지영(Lee, Ji-Young),박일근(Park, Ill-Keun),최태인(Choi, Tae-In) 한국영양학회 2013 Journal of Nutrition and Health Vol.46 No.2

본 연구는 대사증후군 관리를 위한 12주 중재 프로그램으로, 실천지침 이행 정도에 따라 생활습관 변화, 영양소 섭취, 대사증후군 위험인자에 미치는 영향을 알아보고자 하는 목적으로 수행되었다. 1) 연구 대상자는 대사증후군을 가진 남성 근로자로, 모두 기혼자였으며, 교육수준은 높은 편이었다. 12주 중재 프로그램 후 영양성분표시 활용 정도가 유의하게 증가하였으며 과일의 1일 1회 분량 섭취 빈도가 증가하였다. 2) 실천지침 이행률에 따른 신체계측 변화를 살펴보면, 저이행군은 이완기혈압이 감소하였고, 중이행군은 허리둘레의 유의한 감소가 있었다. 고이행군은 수축기혈압, 이완기혈압, LDL콜레스테롤 수치가 유의하게 감소하였고, 고이행군의 수축기혈압과 이완기혈압, LDL콜레스테롤의 변화량은 중이행군보다 유의하게 큰 것으로 나타났다. 3) 저이행군은 단백질과 소금 섭취량, 단백질과 지방의 섭취 비율이 유의하게 감소하였다. 중이행군은 총 열량, 비타민 C의 유의한 감소가 있었으며, 고이행군은 총 열량의 유의한 감소가 있었다. 고이행군은 중이행군에 비해 식이섬유소 섭취량이 유의하게 증가하였다. 4) 저이행군의 대사증후군 위험인자는 3.5개에서 2.8개, 고이행군의 대사증후군 위험인자는 3.3개에서 2.2개로 중재 후 대사증후군 위험인자가 유의하게 적었다. 본 연구 결과 대사증후군을 대상으로 한 식습관 및 생활습관 개선 중재프로그램에서 대상자들의 참여도와 실천정도가 높을수록 건강 개선에 더욱 바람직하였다. 이에 추후 연구에서는 중재 참여 대상자들의 참여율 및 실천지침 이행률을 높여 중재 프로그램의 효과를 극대화할 수 있는 체계적인 프로그램 개발이 이루어져야 할 것이다. This study examined how achievement of session goals contributes to outcomes of subjects after participation in a 12-week lifestyle intervention program in men with metabolic syndrome (MetS). Thirty office workers with MetS, aged 47.2 ± 6.6 years, participated in this study, from March to July, 2011. The intervention program included face-to-face counseling five times during the 12-week period. Counselors and subjects designed session goals for each round. The average of the goal achievement rate was calculated based on compliance for each round. The subjects were divided into three groups according to their tertiles of achievement rate: Low-compliance group (LC, < 59%), medium-compliance group (MC, 59-70%), and high-compliance group (HC, > 70%). Anthropometry, biochemical index, and nutrient intake were examined at baseline and at the end of the 12-week intervention program. After the intervention, diastolic blood pressure (DBP) showed a significant decrease in the LC group, and waist circumference (WC) showed a significant decrease in the MC group. Systolic blood pressure (SBP), DBP, and low-density lipoprotein cholesterol (LDL) showed a significant decrease in the HI group. Changes in SBP and DBP were significantly lower in the HC group than in the MC group (p < 0.05, p < 0.01). Changes in LDL were significantly lower in the HC group than in the MC group (p < 0.05). Results for intake of total energy, protein, fat, and sodium, as well as rates of carbohydrate and fat intake, showed a significant decrease in all participants (p < 0.05). The change in fiber was significantly higher in the HC group than in the MC group (p < 0.05). The change of fruit serving size showed a significant increase in the HC group (p < 0.01). The number of risk factors for MetS showed a significant decrease in the LC and HC groups (p < 0.05), however, no significant mean differences were observed among the three groups. In conclusion, participation in this intervention program resulted in positive effects on risk factors for MetS, nutrient intake, and dietary habits, especially in the High-compliance group. (Korean J Nutr 2013; 46(2): 156 ~ 165)