국가 암조기검진사업 참여에 영향을 미치는 인구사회학적 요인

성나영,박은철,신해림,최귀선,Sung, Na-Young,Park, Eun-Cheol,Shin, Hai-Rim,Choi, Kui-Son 대한예방의학회 2005 예방의학회지 Vol.38 No.1

Background : Cancer is the leading cause of death and one of the largest burdens of disease in Korea. In 1996, the Ten year Plan for Cancer Control was formulated and the government then adopted the plan as a national policy. As part of this plan, the National Cancer Screening Program (NCSP) for Medicaid recipients was formulated, and the government adapted this in 1999. For low-income beneficiaries of the National Health Insurance Corporation (NHIC), the screening program has been in place since 2002. In 2002, the target cancers of NCSP were stomach, breast and cervical cancer. This study was conducted to examine the relationships between the participation rate, the abnormal screening rate and the socio-demographic factors associated with participation in the screening program. Methods : To analyze the participation rate and abnormal rate for the NCSP, we used the 2002 NCSP records. The information on the socio-demographic factors was available from the database of the beneficiaries in the NHIC and Medicaid. Results : The participation rate of the Medicaid beneficiaries for the stomach, breast and cervical cancer screening were 9.2%, 15.5% and 15.0%, respectively, and 11.3% and 12.5%, except cervical cancer which wasn't be included in the NCSP, for the beneficiaries of the NHIC. The abnormal rate of stomach, breast and cervical cancer screening were 25.7%, 11.2% and 21.0%, respectively, for the beneficiaries of Medicaid and 42.6% and 19.4% for the beneficiaries of the NHIC. On the multiple logistic regression analysis, gender, age and place of residence were significantly associated with participation rates of the NCSP. For stomach cancer, women participated in the NCSP more than men. The participation rate was higher among people in their fifties and sixties than for those people in their forties and those people over seventy years in age. For the breast and cervical cancer, people in their fifties were more likely to participate in the NCSP than people in their forties and people over sixty. For the place of residence, people in the rural areas participated more than those people in any other places. Conclusions : The above results show that the participation rate and abnormal rate were significantly associated with the socio-demographic factors. To improve the participation rate for the NCSP, more attention should be given to the underserved groups.

WPM 기반 MemN2N(End-to-End Memory Networks)을 이용한 한국어 뉴스 내용 분류에 관한 연구

성나영(Na-Young Sung ),구명완(Myoung-Wan Koo) 한국정보과학회 2018 한국정보과학회 학술발표논문집 Vol.2018 No.6

여성의 암 검진에 대한 지불의사

곽민선,성나영,양정희,박은철,최귀선,Kwak, Min-Son,Sung, Na-Young,Yang, Jeong-Hee,Park, Eun-Cheol,Choi, Kui-Son 대한예방의학회 2006 예방의학회지 Vol.39 No.4

Objectives: The goal of this study is to measure women's willingness to pay for cancer screening and to identify those factors associated with this willingness to pay. Methods: A population-based telephone survey was performed on 1,562 women (aged 30 years or over) for 2 weeks (9-23th, July, 2004). Data about sociodemographic characteristics, health behaviors, the intention of the cancer screenings and willingness to pay for cancer screening were collected. 1,400 respondents were included in the analysis. The women's willingness to pay for cancer screening and the factors associated with this willingness to pay were evaluated. Results: The results show that 76% of all respondents have a willingness to pay for cancer screening. Among those who are willing to pay, the average and median amount of money for which the respondents are willing to pay are 126,636 (s.d.: 58,414) and 120,000 won, respectively. As the status of education & the income are higher, the average amount that women are willing to pay becomes much more. The amount of money women are willing to pay is the highest during the 'contemplation' stage. Being willing to payor not is associated with a change of behavior (transtheoretical model), the income, the concern about the cancer risk, the family cancer history, the marital status, the general health exam, age and the place of residence. Income is associated with a greater willingness to pay. Old age was associated with a lower willingness to pay. Conclusions: According to the two-part model, income and TTM are the most important variables associated with the willingness to pay for cancer screening. The cancer screening participation rate is low compared with the willingness to pay for cancer screening. It is thought that we have to consider the participants' behavior that's associated with cancer screening and their willingness to pay in order to organize and manage cancer screening program.

소지역 통계 생산을 위한 추정방법

김영원,성나영,Kim, Young-Won,Sung, Na-Young 한국데이터정보과학회 2000 한국데이터정보과학회지 Vol.11 No.1

Small area estimation is becoming important in survey sampling due to a growing demand for reliable small area statistics. In estimating means, totals, and other parameters for small areas of a finite population, samplie sizes for small areas are typically small because the overall sample size is usually determined to provide specific accuracy at a much higher level of aggregation than that of small area. The usual direct estimators that use the only information which is gotten from the sample in a given small area provide unreliable estimates. However, indirect estimators utilize the information from the areas related with a given small area, that is, borrow strength from other related areas, and so give more accurate estimates than direct estimators. In this paper we investigate small area estimation methods such as synthetic, composite and empirical best linear unbiased prediction estimator, and apply them to real domestic data which is from the Survey of Hotels and Restaurants in In-Chon as of 1996 and then evaluate the performance of these methods by measuring average squared errors. This evaluation shows that indirect estimators, which are small area estimation methods, are more efficient than direct estimator. 지방자치제 실시에 따라 우리나라에서도 전국 또는 도 단위의 통계뿐만 아니라 시 군 구 등의 소지역 통계에 대한 수요가 증대되고 있다. 하지만 정부통계 생산을 위해 실시되는 표본조사의 경우 시(특별시, 광역시) 및 도별 통계생산을 목적으로 하기 때문에 신뢰성 있는 소지역 통계를 산출하는 것이 불가능하고, 따라서 이런 소지역 통계생산을 위해 간접 추정 기법을 적극적으로 활용하는 것이 필요하다. 본 논문에서는 정부통계 생산을 위한 소지역 통계 기법의 도입 및 활용 가능성을 검토해 보기 위해 인천광역시 숙박 및 음식점업의 총매출에 대한 구별 소지역 통계를 산출할 수 있는 여러 가지 간접 추정 방법을 제시하고, 아울러 도소매업 총조사 자료를 이용하여 제시된 간접추정량들의 효율성을 비교 분석해 보고자 한다.

암 검진 수검에 영향을 주는 요인

곽민선,박은철,방진영,성나영,이지영,최귀선,Kwak, Min-Son,Park, Eun-Chul,Bang, Jin-Young,Sung, Na-Young,Lee, Ji-Young,Choi, Kui-Son 대한예방의학회 2005 Journal of Preventive Medicine and Public Health Vol.38 No.4

Objectives : We wanted to identify those factors associated with stomach, colon, breast and cervix cancer screening. Methods : A population-based telephone survey was conducted for 2 weeks (the 9th-23th of July, 2004) by trained interviewers with using a questionnaire. 2,598 respondents (females aged 30 years or over, and the males aged 40 years or over) were selected by random-digit dialing that was based on the 2000 Population and Housing Census. The data on socio-demographic, health behavior and enabling factors were collected. 2,571 respondents were included in analysis. The cancer screening rate was classified into 2 categories : the life time screening rate and the screening rate with recommendations. Results : For the 2,571 respondent s, the life time screening rate was as follows: 52.0% (Stomach), 25.3% (Colon), 55.9% (Breast) and 76.8% (Cervix). The screening rate with recommendation was as follows : 3 9.2% (Stomach), 20.6% (Colon), 42.5% (Breast) and 58.3% (Cervix). On a multiple logistic regression analysis of the life time screening, statistically significant relationships were observed for the screening intention, the health exam, the disease history, the age of the patients and the cancer screening rates. On a multiple logistic regression analysis of the screening with recommendation, statistically significant relationships were observed for the screening intention, the health exam, the age of the patients, the concern about the risk of cancer, the voluntary health insurance for cancer and the cancer screening rates. Conclusions : The results of this study suggest that the cancer screening intention, the health exam and the age of the patients are the most important factors to participate in life time cancer screening and also screening with recommendations. A positive association was also observed for the concern about the risk of cancer, the voluntary health insurance for cancer. It is hoped that this study will be a base line data for suggesting the representative cancer screening rate in Korea.

노약자의 응급상황 대응을 위한 안전바 및 응급호출 시스템

나민지 ( Min-ji Na ),배민호 ( Min-ho Bae ),성나영 ( Na-young Sung ),옥석우 ( Seok-woo Ok ),이소용 ( So-yong Lee ),조희진 ( Hee-jin Cho ) 한국정보처리학회 2021 한국정보처리학회 학술대회논문집 Vol.28 No.2

본 작품은 안전 사각지대에 놓여있는 노약자들을 대상으로 낙상을 예방하고, 응급 상황 시 긴급 신고가 가능한 안전바와 응급호출 시스템을 제공한다. 본 작품이 요구하는 각종 기능은 안전바 내부에 센서를 부착하고 그에 맞는 소프트웨어를 추가하여 구현하였다. 또한 어플리케이션을 통해 보호자와 연결되어, 응급상황 시 보호자가 노약자가 처한 상황을 빠르게 인지하여 대처할 수 있도록 하였다.

국민건강보험공단 자료를 이용한 국내 거주 통풍 환자의 유병률과 특성에 관한 연구

이찬희 ( Chan Hee Lee ),성나영 ( Na Young Sung ) 대한류마티스학회 2011 대한류마티스학회지 Vol.18 No.2

Objective. We wanted to evaluate the prevalence of gout and its features in Korean people using the National Health Insurance Corporation (NHIC) database. Methods. Using the NHIC database from 2001 to 2008, we selected the gout patients who were coded as having gout as a main diagnosis. From the total number of gout patients, we evaluated the prevalence of gout and its features. Results. The prevalence of gout prevalence was 0.171% in 2001 and 0.397% in 2008, and there was a 2.317 fold increased during over the 7 years. In 2008, the percentage of fifth and sixth decade patients was 48.5% and that of the male patients were 89.8% of the total gout patients. The increasing rate of the prevalence of gout during the same period was also higher in males (the male vs. female ratio was 5.3:1 in 2001 and 8.8:1 in 2008). The gout prevalence increased year by year to the eighth decade, and the peak prevalence age group was the ninth decade in 2001, the eighth decade in 2002-2005 and the seventh decade in 2006-2008. The prevalence ratio of 2008 to 2001 was higher for the males and the younger age group; that of third decade for males was 9.87, which was over the 10 times higher compared to that of the ninth decade (9.87 vs. 0.89, respectively). Conclusion. The prevalence of gout in 2008 using the NHIC database was 0.397%, so the prevalence of gout increased 2.317 fold over the 7 years, and nearly 90% of the gout patients were male. The increasing rate of gout prevalence was higher in the males and the younger age group.

원인불명의 습관성 유산 환자에서 말초혈액 자연살해세포의 증가가 임신초기 자궁혈류의 변화에 미치는 영향

구화선 ( Hwa Seon Koo ),이현정 ( Hyun Jeong Yi ),이민영 ( Min Young Lee ),안현숙 ( Hyun Suk Ahn ),최민혜 ( Min Hye Choi ),성나영 ( Na Young Sung ),황유임 ( Yu Im Hwang ),송인옥 ( In Ok Song ),궁미경 ( Mi Kyoung Koong ),강인수 ( In 대한산부인과학회 2012 Obstetrics & Gynecology Science Vol.55 No.7

목적: 원인불명의 습관성 유산 환자에서 말초혈액 중 비정상적 비율로 증가된 자연살해세포가 자궁으로의 혈류를 감소시키는지에 대해 알아보고자 하였다. 연구방법: 본 연구는 전향적 연구로, 습관성 유산의 기왕력을 갖는 임신 5-7주 사이의 환자 33명을 대상으로 하였으며 습관성 유산의 기왕력이 없는 정상 임신 5-7주 47명을 대조군으로 하였고, 습관성 유산군은 말초혈액 자연살해세포 비율 12.1%를 기준으로 정상(normal) natural killer (NK) group과 증가(elevated) NK group으로 나누어 연구를 진행하였다. 임신 5-7주 사이에 측정한 말초혈액에서 유세포분석기를 이용하여 말초혈액 자연살해세포 분획 및 세포용해 활성도를 측정 후 그 결과를 비교 분석하였고 질식초음파의 Doppler를 이용하여 자궁방 사동맥의 저항을 측정 후 각 군에서 비교하였다. 또한 말초혈액 자연살해세포분획과 자궁방사동맥 저항지수 간의 연관성을 알아보았다. 결과: 자궁방사동맥의 평균 저항지수는 대조군에 비교하여 습관성 유산 환자군에서 통계학적으로 의미 있게 높았고(0.60 ± 0.14 vs. 0.54 ± 0.12, P = 0.039), 말초혈액 자연살해세포의 분획이 12.1% 이상 증가(elevated NK)군에서도 정상대조군에 비해 통계학적으로 유의하게 높게 나타났다(0.62 ± 0.13 vs. 0.54 ± 0.12, P = 0.029). 또한 전체 습관성 유산 환자에서 말초혈액 자연살해세포의 비율과 자궁방사동맥 저항지수 사이에는 양의 상관관계가 나타났고(P = 0.013, r = 0.429), 특히 습관성 유산 환자중 증가(elevated) NK군에서는 더욱 강한양의 상관관계를 보였다(P = 0.001, r=0.667). 결론 증가된 말초혈액의 자연살해세포는 자궁방사동맥과 같은 미세 혈관에 향염증 반응을 일으켜 자궁으로의 혈류를 감소시켜 습관성 유산을 야기한다고 설명할 수 있겠다. 하지만 본 연구의 결론을 확인하기 위해서는 더 큰 규모의 연구뿐 아니라 분자생물학적 기전에 대한 연구도 필요할 것으로 생각된다. Objective: To evaluate whether increased peripheral blood inflammatory immune cell can induce decrease of uterine blood flow in patients with unexplained recurrent spontaneous abortion (RSA). Methods: This study designed prospectively 33 pregnant women between 5 to 7 gestational weeks with a history of unexplained RSA included in this study. 47 normal pregnant women between 5 to 7 gestational weeks without history of infertility and/or RSA included as a control. Peripheral blood natural killer (pbNK) (CD3-/56+) fractions among peripheral blood monocyte (PBMC) were checked by flow cytometry. Uterine color-pulsed Doppler trans-vaginal ultrasound for evaluation of uterine radial artery RI was checked. Uterine radial artery resistance index (RI) compared between study and control group. After then, uterine radial artery RI was compared between high pbNK cell fraction above 12.1% among PBMC and normal pbNK cells fraction below 12.1%, Correlation between pbNK cell fraction to uterine radial artery RI was also evaluated, Results: Uterine radial artery RI in early pregnancy was significantly higher in patients with RSA than that of normal control (0.60 ± 0.14 vs. 0.54 ± 0.12, P = 0.039). Especially, the mean value of uterine radial artery RI in RSA patients with elevated pbNK cells was significantly increased than that of normal control (0.62 ± 0.13 vs. 0.54 ± 0.12, P=0.029). Otherwise, pbNK cell fractions among PBMC displayed strong positive correlation to uterine radial artery RI (Pearson`s correlation coefficient P=0.001, r = 0.667). Conclusion: Increased pbNK cells can evoke decreased uterine blood flow by their pro-inflammatory action on micro vascular structure such as uterine radial artery. This can be a one causative mechanism of inducing spontaneous abortion by increased NK cells. But, larger scaled study is needed for clarify our results.

신종 인플루엔자 A (H1N1) 감염으로 입원한 성인 폐렴 환자의 임상양상

한창훈 ( Chang Hoon Han ),현여경 ( Yu Kyung Hyun ),최유리 ( Yu Ri Choi ),성나영 ( Na Young Sung ),박윤선 ( Yoon Seon Park ),이꽃실 ( Kkot Sil Lee ),정재호 ( Jae Ho Chung ) 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.69 No.1

Background: A novel 2009 influenza A (H1N1) virus emerged and disseminated to all over the world. There are few reports on the clinical characteristics of patients with complications. We describe the clinical features of pneumonia in adult patients hospitalized, who have novel influenza infection. Methods: There were 43 adult patients enrolled into the study with pneumonia of 528 hospitalized patients confirmed influenza A (H1N1) virus infection by real-time reverse transcriptase polymerase chain reaction testing, between 24 August 2009 and 31 January 2010. The clinical data of patients with pneumonia were collected retrospectively. Results: There were 22 of 43 (51.2%) influenza patients with pneumonia that had higher risk factors for complications. Compared to 28 patients with influenza A (H1N1) viral pneumonia and 15 patients, who had isolated bacteria from cultures, those with mixed viral and bacterial pneumonia were significantly more likely to have unilobar consolidations on chest radiographs (53.3 vs. 10.7%, p<0.01) and higher scores of pneumonia severity index (PSI; 90 [66~100] vs. 53 [28~90], p=0.04). Six patients required mechanical ventilation support in an Intensive Care Unit and were more likely to have dyspnea (83.3 vs. 29.3%, p=0.02) and low levels of PaO2 (48.3 [37.0~70.5] vs 64.0 [60.0~74.5] mm Hg, p=0.02) and high levels of pneumonia severity index (PSI) score (108.0 [74.5~142.8] vs. 56.0 [40.5~91.0], p=0.03). Conclusion: The majority of pneumonia patients infected with novel influenza improved. Chest radiographic findings of unilobar consolidations suggest that mixed pneumonia is more likely. Initial dyspnea, hypoxemia, and high levels of PSI score are associated with undergoing mechanical ventilation support.

생식샘자극호르몬 분비호르몬 길항제를 이용한 난소자극 투여법에서의 경구복합피임제의 전처지: 비교 연구

추연실 ( Youn Sil Choo ),한애라 ( Ae Ra Han ),양승헌 ( Seung Heon Yang ),성나영 ( Na Young Sung ),차선화 ( Sun Hwa Cha ),김혜옥 ( Hye Ok Kim ),박찬우 ( Chan Woo Park ),송인옥 ( In Ok Song ),궁미경 ( Mi Kyoung Koong ),강인수 ( In S 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.10

목적 생식샘자극호르몬 분비호르몬 길항제를 이용한 난소자극 투여법에서 경구복합피임제의 전처치가 체외수정시술의 결과에 미치는 효과에 대해 평가해 보고자 하였다. 연구방법 2009년 9월 1일에서 2010년 2월 28일까지 본원 불임센터에서 체외수정시술을 위해 총 194회의 생식샘자극호르몬 분비호르몬 길항제 요법을 시행한 환자 중 경구복합피임제를 전처치한 경우와 그렇지 않은 경우의 체외수정 및 배아이식술의 진료 기록을 찾아 후향적으로 분석하였다. 결과 경구복합피임제 전처치군의 경우 사용된 생식샘자극호르몬의 사용량이 전처치하지 않은 군보다 많았다(3019.38±1379.00 vs. 2551.52 ± 1157.05 IU, P = 0.054). 난소 자극 시작부터 난소 채취를 위한 마지막 생식샘자극호르몬의 투여일까지 기간 또한 경구복합피임제 전처치 군(11.5 ± 2.0)에서 전처치하지 않은 않은 군(9.5 ± 1.9)에 비해 통계학적으로 의미 있게 길었다(P = 0.000). 배아 총 획득 갯수(2.8 ± 0.9 vs. 2.5 ± 1.0, P = 0.055) 및 난자수정률(77.2% vs. 65.5%, P = 0.017) 또한 경구복합피임제 전처치 군에서 처치 하지 않은 군에 비해 통계학적으로 의미 있게 높았다. 한편, 임신율에 있어서는 두 그룹 간에 통계학적으로 유의한 차이가 없었다(39.4% vs. 30.0%; P = 0.0304). 결론 체외수정시술을 위한 생식샘자극호르몬 분비호르몬 길항제 사용 시 경구복합피임제를 전처치 하였을 때, 그렇지 않은 군에 비해 최종적인 체외수정시술의 결과적인 측면에서 현저한 장점은 없는 것으로 보인다. 하지만 좀 더 명확한 결론을 도출하기 위해서는 더 많은 연구군을 포함한 전향적인 연구가 필요할 것으로 생각된다. Objective To evaluate whether oral contraceptive pill (OCP) pretreatments in gonadotropin-releasing hormone (GnRH) antagonist ovarian stimulation protocols takes positive effects on in vitro fertilization (IVF) outcomes in respect to retrieved oocyte number, oocyte maturation rate, fertilization rate, good quality embryo rate, cycle cancellation rate, pregnancy rate and clinical abortion rate. Methods A total of 194 cycles using GnRH antagonist protocol was performed at infertility clinic of our institute from September 1st, 2009 to February 28th, 2010. The medical records of GnRH antagonist protocols for IVF with or without OCP pretreatment in our IVF unit were retrospectively analyzed. We compared the IVF outcomes between OCP pretreated (n=41) and no pretreatment group (n=153). Results In cycles with OCP pretreated group, the total used dosage of gonadotropin (3019.38±1379.00 IU) were higher than that of no pretreatment group (2551.52 ± 1157.05 IU, P = 0.054). The duration of ovarian stimulation in OCP pretreated group (11.5 ± 2.0) was significantly longer than that of control group (9.5 ± 1.9, P = 0.000). The number of gained total embryo (2.8±0.9 vs. 2.5±1.0, P = 0.055) and fertilization rate (77.2% vs. 65.5%, P = 0.017) were significantly higher in OCP pretreated group. There is no significant difference in pregnancy rate between two groups (39.4% vs. 30.0%, P = 0.304). Conclusion OCP pretreatment before GnRH antagonist protocol for IVF appears not to have reliable benefit in terms of IVF outcomes. Wellcontrolled and large-scaled studies are needed.