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비장을 침범하여 비장낭종으로 자라난 췌장의 점액성 낭선암 1 예
김기훈(Ki Hun Kim),박성호(Sung Ho Park),서호종(Ho Jong Seo),최진욱(Jin Wook Choi),김광석(Kwang Seok Kim),고성만(Sung Man Go),서광섭(Kwang Seop Seo),김홍자(Hong Ja Kim),김호정(Ho Jung Kim),강유미(Yoo Mee Kang) 대한소화기학회 2001 대한소화기학회지 Vol.38 No.6
Mucinous cystic neoplasms of the pancreas are rare primary tumors. They are low-grade tumors that occur predominantly in middle-aged woman. They usually arise within the tail of the pancreas and manifest as large, multiloculated cystic masses. In most cases, they are confined to the tail or body of the pancreas. All mucinous cystic neoplasms should be considered as mucinous cystadenocarcinomas of low-grade malignant potential. Complete surgical excision alone results in an excellent clinical outcome. We experienced a case of mucinous cystadenocarcinoma of the pancreas with invasion to the spleen in a 66-year-old woman. The mucinous cystadenocarcinoma involving the spleen is extremely rare and there has been no case report in Korea. Distal pancreatectomy and splenectomy was performed. It was concluded that multiloculated cyst developed from pancreatic tail and manifested as a huge splenic cyst. We report this rare case with a review of literature.(Korean J Gastroenterol 2001;38:453-456)
서호종,김기훈,박성호,최진욱,김광석,고성만,서광섭,김홍자,김호정,허병원,김해경 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.3
Ulcerative colitis(UC)is a disease that affects the mucosal lining of the colon. Epidemiologlcal studies revealed that UC is global in distribution and the incidence has risen in recent decades. The pathogenesis of UC, remains uncertain. However, recent studies have suggested that colonic environment, most notably bacteria flora, genetic susceptibility, mucosal defects, immunologic abnormalities, altered levels of specific cytokine and inflammatory mediators,and dietary factors are implicated. The major symptoms of ulcerative colitis include diarrher, abdominal pain, and hematochezia(rectal bleeding). Ulcerative colitis also may be complicated by many local and systemic disorders as extracolonic symptoms. Erythema nodosum is one of the most frequent dermatologic complications associated with ulcerative colitis. It is an acute, painful, rective skin inflammation of unknown cause. Physicians can disgnose clinically, since there is no accepted histological diagnostic criteria. Conventational therapy is preferred to control causative disease. We authors experienced a case of suppurative erythema nodosum on both shins of ulcerative colitis patient, which was treated with high dose corticosteroids and discharged with clinical improvement of dematologic manifiestation, coincidently controlled acute exacerbation of the bowel disease. So we report this case with a brief literature review.
Azithromycin으로 치료한 임신 중 쓰쓰가무시병 1예
김광석,최진욱,서호종,김기훈,박성호,서광섭,고성만,김순혜,김호정 대한감염학회 2001 감염 Vol.33 No.5
We report a case of tsutsugamushi disease in a 26 year-old pregnant woman who was treated with azithromycin. Her gestation period was 27 weeks and she admitted with fever, rash, and eschar on the right shoulder. Currently recommended medications for the treatment of scrub typhus are doxycycline or chloramphenicol. But, these drugs are class D drugs according to the U.S. Food and Drug Administration (FDA) Fetal Risk Summary, so they couldn't be used to treat pregnant women. Recently, a few case reports suggested that azithromycin, a relatively new macrolide antibiotic, was effective and safe for the treatment of scrub typhus in pregnant women. And, there is no evidence that azithromycin causes harmful effects to the developing fetus or to children. On the basis of current in vivo test that confirms the effectiveness of azithromycin, it may be the drug of choice for the treatment of scrub typhus in pregnant women and children. (Korean J Infect Dis 33:380-382, 2001)
간동정맥 단락을 동반한 유전성 출혈성 모세관 확장증 1례
최진욱,김호종,박성호,최대섭,김종숙,김광석,김해경,서호종,김기훈,김지겸 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.4
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant inherited disease characterized by telangiectasias of the skin, mucous membranes, and various organ system. HHT is not unusual in western countries but there were several reported cases of HHT in Korea. Recently we evaluated a 40-year-old postpartum female who had been suffering from recurrent epistaxis and peripartum dyspnea. The patient was diagnosed as a HHT complicated by high output heart failure caused by intrahepatic arteriovenous malformation. This case is reported with a review of relevant literature.(Korea J Hepatol 2000;6:514-518).
고성만,김기훈,서호종,서광섭,유광렬,채선애,임병욱,김홍자,김호정,김진승,허병원,김해경 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.3
The superficial spreading type of early gastric cancer has usually been defined as an early gastric cancer in which the product of the longest diameter and the diameter perpendicular to it was greater than 25㎠. Although the superficial spreading type of early gastric cancer is histologically aggressive compared with those without such histological aggressiveness, the 5 year survival rate is as good as a non-superficial spreading types of early gastric cancers if the wide surgical resection with extensive lymph node dissection is performed as a treatment. We experienced a case of superficial spreading early gastric cancer in a 59-year-old man. This case is reported with a brief review of related literature.
최진욱,김기훈,서호종,김광석,박성호,김창훈,강남훈,김희수,권영우,김홍자,김호정,김수아,박용휘 대한내과학회 2002 대한내과학회지 Vol.62 No.5
The most common developmental anomaly of midgut rotation and fixation is non-rotation. Symptomatic intestinal malrotation is relatively common in infants and children but uncommon in later ages. Most adult cases are silent throughout life and are not discovered unless they cause acute or chronic abdominal pain. Many such patients have ill-defined abdominal complaints and are labeled as having a “functional” disorder since no definite clinical abnormalities are found other than the subjective complaints. The most frequent symptomatic presentation in the adult is midgut volvulus the symptom of which is usually self-limited although often recurrent and sometimes leading to an abdominal catastrophe. The diagnostic means for the adulthood malrotation include simple and contrast radiographic studies and CT scan. Malrotation first detected by cholescintigraphy is rare. We report a case of intestinal non-rotation incidentally discovered on DISIDA hepatobiliary scintiscan.
종양표지자 CA19-9의 현저한 상승을 보인 급성 담도염 1예
박성호,김기훈,서호종,최진욱,김광석,서광섭,고성만,김홍자,김호정,허병원,김해경 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.3
Doubts about effectiveness of CA19-9 are arsing since CA19-9 may show false positive with increase in blood in such cases of not only malignant tumor, but also acute cholangitis caused by gall stone or biliary obstuction. In such case, it is helpful in differentiating from malignant tumor to adjust the standard level of CA19-9 higher up to 300U/ml, or to reexamine after treament of initial acute inflammation or drainage of bile caused by biliary obstuction. The patient of 64-year-old female whose chief complaints were epigastric pain, fever and chilling sensation. The AST/ALT was 100/120 IU/L and alkaline phosphatase was 325IU/L and her initial level of Ca19-9 was 1,522U/mL and showed a significant increase. On ultrasonography and ERCP there was diffuse dilatation of common bile duct and intrahepatic duct without luminal obstruction. Conservative treatments and antibodics treatment for acute inflammation was applied reexamination thereafter showed the decreased and normal CA19-9 level of 22.4U/mL and liver function test.