폐내의 장관성 낭종 1례 보

서의수 대한흉부심장혈관외과학회 1987 Journal of Chest Surgery (J Chest Surg) Vol.20 No.3

A very rare form of intrapulmonary cyst is an enterogenous cyst two examples of which were described by Ward and Krahl [1942]. Microscopically, the cyst wall is lined by gastric or intestinal type of mucous membrane which may include islets of pancreatic tissue; their walls contain muscle but no cartilage. We recently experienced a case of intrapulmonary enterogenous cyst. The patient was 30-year-old-male who showed chest pain and tightness after chest trauma. Chest X-ray revealed pneumothorax in both lung field with giant bullae in left upper lung field, right 6th and 7th rib fracture. Left lower lobectomy including cyst was done and the postoperative course was uneventful.

週齡에 따른 생쥐 Leydig세포의 전자현미경적 구조

서의수,박매자,김덕훈,주강 慶北大學校 醫科大學 1990 慶北醫大誌 Vol.31 No.3

주령(週齡)의 증가에 따른 생쥐 Leydig세포의 광학현미경형태와 초미세구조에 관한 변화는 다음과 같다. 1. 생후 1주군에서 미분화된 Leydig세포는 정세관 주위에서 관찰할 수 있었고, 핵은 방추형이며, 핵질과 핵막에는 이염색질이 많이 분포하고, 세포질에는 소포체와 사립체가 조금 분포하나 그 이외의 세포소기관은 거의 없었다. 2. 3주군에서의 Leydig세포는 아직 완전히 분화되지는 않았으나 정세관 주위에서 관찰되었다. 핵은 난형이며, 핵막의 일부 함입과 이염색질의 부착이 있고 세포질에는 잘 발달된 무과립성 내형질망과 membrane whorl이 있으나 그 이외 세포소기관의 발달은 미약하였다. 3. 5주군에서는 완전히 분화한 Leydig세포들의 군집이 정세관 주위에서 관찰되었다. 핵은 거의 원형이며, 핵에는 진염색질이 분포하며, 세포질에는 사립체의 발달이 현저하고, 그 이외의 세포소기관은 약간 증가하였다. 4. 7주군에서는 잘 발달된 정세관의 구조와 잘 분화된 Leydig세포들의 군집을 tubule의 각 공간에서 관찰할 수 있었다. 세포는 핵이 원형으로, 핵막은 뚜렷하고 세포질에는 무과립성 내형질망, 지방소적, 용해소체, 사립체, 당원입자 등이 아주 잘 발달되어 있었다. This study was performed to investigate the ultrastructure of the Leydig cell on aging of the mouse. The results obtained were as follows. One week after birth: The undifferentiated Leydig cells are found around seminiferous tubules. The nucleus showed the fusiform shape. The heterochromatin was found to be adherent to the nuclear membrane and to be dispersed in the nucleoplasm. The smooth endoplasmic reticulum and mitochondria were poorly developed, and the other cell organelles did not appear at this stage. The cytoplasmic vacuolations began to appear. After 3 weeks: Not fully differentiated Leydig cells are present around tubules. The nucleus had oval shape, and some nuclear membrane was caved and adhered to the heterochromatin. The smooth endoplasmic reticulum and membrane was caved and adhered to the heterochromatin. The smooth endoplasmic reticulum and membrane whorl were well developed. But the other cell organelles were poorly developed. After 5 weeks: Clusters of fully differentiated Leydig cells are found around the tubules. The nucleus had round shape, and the nucleoplasm included an euchromatin. Numerous mitochondria were ovserbed at this stage. After 7 weeks: Clusters of fully differentiated Leydig cells are located in the interspace of each tubules. The shape of nucleus was round, and nuclear membrane was prominent. The smooth endoplasmic reticulum, lipid droplets, lysosomal dense body, mitochondria, ribosome and glycogen were increased markedly in number.

삼첨판 폐쇄증 Type Ic의 변형 Fontan 수술 치험 1례

서의수 대한흉부심장혈관외과학회 1990 Journal of Chest Surgery (J Chest Surg) Vol.23 No.5

The Fontan operation for tricuspid atresia was first performed in 1968[Fontan and Baudet 1971] and several technical modifications of procedure were developed. We have experienced a case of modified Fontan operation for tricuspid atresia type Ic who was 5 years old female. She had previous palliative procedure \ulcornerpulmonary artery banding due to excessively increased pulmonary blood flow. The modified Fontan operation was right atrium to right ventricle connection with valve-bearing conduit. The result was good and the patient was discharged 20 days after operation.

폐포충낭종 -2예 보고-

서의수 대한흉부심장혈관외과학회 1989 Journal of Chest Surgery (J Chest Surg) Vol.22 No.3

Echinococcal or hydatid cyst is one of the most important zoonoses and commonly seen throughout the world, especially sheep and cattle raising areas, but rare in Korea. The causative organism, Echinococcus granulosus, is a small tapeworm and dogs are the usual source of infestation. Lung is the second most common focus for this disease, after liver. Recently, with increasing numbers of Koreans visiting to those endemic countries especially Middle East, the reports of hydatidosis are increasing. Authors experienced two cases of pulmonary hydatid cyst in the 31 year old male and 44 year old male who had a history of spending 2 * 3 years in Middle East. we found them in incidental routine chest X-ray.

개심술후 재수술에 대한 임상적 고찰

서의수 대한흉부심장혈관외과학회 1989 Journal of Chest Surgery (J Chest Surg) Vol.22 No.1

The emergence and expansion of cardiac surgery over the past decade has resulted in an increasing number of patients undergoing cardiac operations but many kinds of heart surgery was realized only palliative, resulting in increasing numbers of secondary cardiac procedures. From 1978 to 1988, 10 cases of various congenital heart diseases and 17 cases of acquired heart diseases were reoperated at Hanyang University Hospital. The leading indication of second operation was residual shunt or valvular malfunction due to technical failure in congenital heart disease and primary valve failure, endocarditis, paravalvular leakage were for acquired heart disease. The mortality of reoperation was 0% for congenital heart disease and 11.7%[2 death among the 17 patients] for acquired heart disease. The leading causes of death were myocardial failure, sepsis with endocarditis, acute renal failure and congestive heart failure.

폐상피양세포암 조직 acid deoxyribonuclease의 작용 기전에 관한 연구

고재경,지행옥,서의수 한양대학교 의과대학 1991 한양의대 학술지 Vol.11 No.2

Activities of deoxyribonucleases (DNases) were determined in lung cancer tissues and were compared with those in the control lung tissuse. Of the DNases studied in the present work, acid DNase was isolated and purified from the epidermoid carcinoma tissue of the lung. The partially purified enzyme was used for characterizing properties of the acid DNase and for exploring the mechanism of action of the acid DNase from the epidermoid carcinoma of the lung. 1.Activities of acid, neutral and alkaline DNases in the lung cancer tissues were all singnificntly increased as compared with those in the control tissues of the lung, and the degree of increment in the enzyme activity was the highest in acid DNase of the epidermoid carcinoma tissue of the lung (129% increase). The positive rate of acid DNase in the lung tissue as a marker for epidermoid carcinoma of the lung as a biochemical marker for the epidermoid carcinoma of the lung. 2.DEAE-cellulose column chromatographical analysis for acid DNase and proteins in the control tissue and epidermoid carcinoma tissue of the lung revealed that tissue and that proteins were isorated into 7 peaks for the cancer tissue and 8 peaks for the control tissue. These results indicated that no acid DNase specific to the lung cancer was found in the cancer tissues and that a protein present in the control lung tissue disppeared from the lung cancer tissue. 3.Acid DNase in the epidermiod carcinoma tissue of the lung was partially purified by 58-fold by methods of centrifugation and an ion exchange column toward ds DNA and exhibited both endo-and exo-nuclease activities. These results indicate that acid DNase activity is significantly increased in the lung cancer tissue, but the possibility of the enzymed. Further studies are needed to purify the acid DNase more extensively to clearify and elucidate the mechanism of action of the enzyme in such tissues.

부신선종에 의한 원발성 Aldosterone증의 치험 1예

박창순,김병곤,손호상,서의수,백영직,배정동 대한내분비학회 1988 Endocrinology and metabolism Vol.3 No.1

A 42-year-old woman with intracerebral hemorrhage, severe hypertension (210/130 mmHg), hypokalemia (2.4 mEq/L) and suppressed plasma renin activity (PRA) demonstrated fixed PRA level that did not change during volume depletion (upright posture, sodium depletion) and aldosterone level that decreased during upright posture. Blood pressure was stabilized with spironolactone.Computerized transaxial tomography was diagnostic of a discrete adrenal lesion. Right adrenalectomy revealed adrenocortical adenoma. Postoperatively, there was a reversal of hypertension, htpokalemia and muscle weakness. Thus we present one case of primary aldosteronism due to unilateral adrenocortical adenoma with brief review of literatures.

호흡부전증으로 사망한 비전형적 Wegener 씨 육아종증 1 예

김병곤,박창순,신진식,이상채,서의수,손호상 대한내과학회 1987 대한내과학회지 Vol.32 No.5

Wegener's granulomaosis is necrotizing and granulomatouus vasculitis which involves chiefly upper and lower respiratory tract and kidney. A preponderence of involvement in the upper respiratory tract and the easy access to the nose and nasopharynx for biopsy make this disorder important for the head and neck surgery. Two cases which were localized to the upper air-way, were reported in Korea. This case was recurred in lung, pleura and kidney, after the diagnosis had been made by operative procedure, cyclophosphamide and steroid therapy had been done for about 2 years, and the disease had been remitted. The patient was died of respiratory failure, not renal failure or sepsis which were generally the causes of death, inspite of cyclophosphamide, steroid, and antibiotic therapy. So authors report this case with references.

노인요양시설 종사자의 근골격계 증상이 친사회적 행동에 미치는 영향: 서비스지향성의 매개효과를 중심으로

김관용 ( Kim Gwanyong ),서진숙 ( Seo Jin Suk ),곽의수 ( Kwak Euisoo ),장은석 ( Jang Eunseok ) 한국보건사회연구원 2016 保健社會硏究 Vol.36 No.4

본 연구는 노인요양시설 종사자의 근골격계 증상이 친사회적행동에 미치는 영향관계 속에서 서비스지향성의 매개효과를 중심으로 살펴보았다. 이러한 연구를 위해 서울특별시의 80개 노인요양시설 종사자 400명을 대상으로 우편 및 방문을 통하여 조사를 하였다. 61개 시설 302명의 종사자들이 설문에 응답하였으며, 최종 분석에는 295명의 응답내용이 사용되었다. 매개 회귀분석에 의한 주요한 연구결과는 다음과 같다. 첫째, 근골격계 증상은 친사회적행동에 통계적으로 의미 있는 영향을 미쳤다. 둘째, 근골격계 증상과 서비스지향성을 함께 투입했을 때는 서비스지향성만 영향을 미쳤다. 결과적으로 매개변수 서비스지향성은 완전매개효과를 나타내는 것으로 드러났다. 이것은 친사회적 행동에 영향을 미치는 변수인 근골격계 증상의 효과와 비교할때 서비스지향성이 더 중요한 변수로 밝혀졌다는 것을 의미한다. 그러나 근골격계 증상이 매개변수인 서비스지향성을 통하여 영향을 미치는 간접적인 효과를 나타냈기 때문에 그만큼 근골격계 증상의 중요성도 강조되어야 할 것이다. 이를 토대로 본 연구에서는 노인요양 시설에서 종사자들의 친사회적행동을 높이기 위한 근골격계 증상관리 방안과 서비스지향성을 높이기 위한 방안을 제시하였다. This study mainly examines the mediating effect of service orientation in the relationship between musculoskeletal symptoms and the pro-social behavior of elderly care facility employees. For this study, we investigated through mails and visits to target a total of 400 employees at 80 facilities in Seoul. Of these, 302 employees at 61 facilities responded to the survey, and we used the responses from 295 employees for the final analysis. Major findings of our mediated regression analysis are as follows. First, musculoskeletal symptoms had a statistically significant impact on pro-social behavior. Second, when we put together the musculoskeletal symptoms and service orientation, only service orientation had an impact. As a result, service orientation parameters turned out to be the perfect mediating effect. Based on this, this study proposed a management plan musculoskeletal symptoms and ways to improve the service orientation to enhance the pro-social behavior of employees in elderly care facilities.

간장 및 담도 : 만성활동성간염의 HBsAg 양성 및 음성군간의 임상적 비교 관찰

배정동(Jung Dong Bae),박윤현(Yoon Hyun Park),신진식(Jin Sik Shin),서의수(Euy soo Suh),박창순(Chang soon Park) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.1

N/A From August 1982 to February 1986, clinical study was performed at the Daegu Catholic Hospital on 38 patients with chronic active hepatitis proven by biopsy, and their contrasting features of chronic active hepatitis with and without HBsAg were studied. The results are as follows: 1) The 38 patients with chronic active hepatitis were allocated to two groups based on the detection of the HBsAg by counterimmunoelectrophoresis and/or reversed passive hemagglutination technic 22 cases(57.9%) were considered to have HBsAg positive chronic active hepatitis, while the remaining 16 cases(42.1%) were considered to have HBsAg negative chronic active hepatitis. The sex distrbution was 16 in male and 6 in female with a mean age of 34. 7 among HBsAg positive groups, and 10 in male and g in female with a mean age of 45.6 among HBsAg negative groups. 2) Duration of symptoms before entry appeared to be slightly longer in HBsAg negative groups than in positive groups, but there were no significant differences between both groups. 3) There were also no significant differences between HBsAg positive and negative patients for clinical symptoms and signs. 4) There were also no significant differences between HBsAg positive and negative groups in most of liver function tests. 5) Responses to the treatment with prednisone appeared to be slightly better in HBsAg negative groups than in positive groups, but they were no significant differences between both groups.