정신적 스트레스와 만성 장 질환

은창수,변영재 한양대학교 의과대학 2014 Hanyang Medical Reviews Vol.34 No.2

Psychological stress induces alterations in the function of the hypothalamic-pituitary-adrenal axis via corticotorphin releasing factor and alterations in the enteric nervous system via actions of the autonomic nervous system. Mucosal mast cells and adrenal glands release several inflammatory cytokines and cortisol, causing increased intestinal permeability. Increased intestinal permeability as well as increased inflammatory cytokines and hormones cause changes in bacterial-mucosal interactions, leading to the aggravation of disease activity and gastrointestinal symptoms in inflammatory bowel syndrome (IBD) and irritable bowel syndrome (IBS). Several studies have demonstrated that stress has an important roles in the pathogenesis of IBD and IBS. Personal traits, health beliefs and personal stress-coping mechanisms can also have adverse effects on the disease course of IBD and IBS. Stress reduction therapies have been adapted for treatment of IBD and IBS. Antidepressants and psychological therapies such as cognitive-behavior therapy, hypnotherapy, and multi-component psychological therapy have been used for control of disease activity and symptoms in IBD and IBS patients. The efficacy of such treatments is controversial, because there has not been an adequate standardization in treatment protocol, and studies suffer from the difficulties involved in selection of appropriate control groups, questions related to a high placebo effect, as well as differences in interpretation. Well-designed prospective controlled studies evaluating the role of stress in the pathogenesis of IBD and IBS and the role of stress reduction therapies are warranted for improvement of clinical treatments and outcomes.

개에서 발생한 신암종 3례

변예은,임지혜,정창수,오상연,김대용,최민철,윤정희,김완희,권오경 한국임상수의학회 2005 한국임상수의학회지 Vol.22 No.3

Three dogs that had a history of abdominal distension were referred to the hospital. All were female with unilateral involvement. History and clinical signs were nonspecific. Abdominal radiographs demonstrated that the abdomen of all cases was filled with large masses. At laparotomy, all masses were kidney tumors with invasion around tissue. The tumors were soft, irregular, creamish and confined within the capsule. One case had liver metastasis. Another case was found to have adrenal gland metastasis. One case had caudal vena cava invasion. A ureteronephrectomy was performed unilaterally in all cases. In the microscopic appearances, all the tumors had malignant features with nuclear pleomorphism and amount of necrosis. Three cases were diagnosed as renal carcinomas.

개의 전배측 고관절 탈구에서 변형된 외골격 고정 적용 5례

정창수,임지혜,변예은,김완희,윤정희,권오경 한국임상수의학회 2007 한국임상수의학회지 Vol.24 No.4

Luxation of the hip is the most common luxation seen in small animals. Luxations are classified by thedirection in which the femoral head lies in relation to the acetabulum.and craniodorsal luxations are the most commontype. Recommendations for treatment are based on the presence of preexisting disease, the type and duration of luxationand severity of concurrent injuries. In this study modicoxofemoral luxation in 5 dogs. Luxated head Joint was reduced and fixator pins were applied into the greater trochanter,the middle point of iliac body and the lateral surface of sacroiliac joint in a closed fashion. Reduction was successfulin 4 of the 5 operated limbs. Complications noted in this study included pin tract drainage, pin loosening and secondaryfracture at the pin insertion site.

웨이브렛 형태학 알고리즘 적용한 객체 분할의 클러스터링 분석

백덕수,강창수,변오성 대한전자공학회 2006 電子工學會論文誌 IE (Industry electronics) Vol.43 No.2

This paper is proposed the wavelet morphology algorithm with the spatial auto-object segmentation concept and the clustering concept. When it is segmented the color face by using the proposed algorithm, it is made to the simple image. Also, it is used the spatial quality in order to segment and detect the image as a real time without the user's manufacturing. This removed a small part that is regarded as a noise in image by HSV color model and applied the wavelet morphology to remove a part excepting for the face image. In this paper, it is made a comparison between the wavelet morphology algorithm and the morphology algorithm. And It is showed to accurately detect the face object parts in the image appled to HSV color space model. 본 논문은 공간적 자동 객체 분할의 개념과 클러스터링 개념을 가진 웨이브렛 형태학 알고리즘을 제안하였다. 제안된 알고리즘을 이용하여 컬러 얼굴을 분할할 때 영상을 단순화하였으며, 또한 사용자의 조작 없이 실시간적으로 분할해 검출할 수 있도록 공간적 특성을 이용하였다. 이것은 HSV 컬러 모델을 이용하여 영상에서 잡음으로 간주되는 작은 부분을 제거하고, 얼굴 영상 이외의 부분을 제거하기 위해 웨이브렛 형태학을 적용하였다. 본 논문은 웨이브렛 형태학 알고리즘과 형태학 알고리즘을 비교하였으며, 그리고 HSV 컬러 공간 모델을 적용한 영상에서 얼굴 객체 부분을 정확하게 검출함을 보였다.

소형견에서 섬유연골 색전성 척수증 2례

임지혜,정창수,변예은,김완희,이영원,권오경 한국임상수의학회 2006 한국임상수의학회지 Vol.23 No.3

태양집광판과 가로등의 유지보순 기술 향상을 위한 자동 승하강장치 시작품 설계 제작

이재용,변창수,송현직,Lee, Jae-Yong,Byun, Chang-Soo,Song, Hyun-Jig 한국조명전기설비학회 2008 조명·전기설비학회논문지 Vol.22 No.6

본 논문에서는 고공시설물인 태양집광판을 사용한 가로등의 집광효율과 유지보수 성능 향상을 위한 자동 승하강 장치를 설계 제작하였다. 자동 승하강장치는 태양집광판을 사용한 가로등과 유기적으로 동작가능하곤 태양집광판의 집광 각도를 조절하여 집광효율을 향상시킬 수 있다. 또한 태양집광판과 가로등을 쉽게 탈부착할 수 있는 구조로써 유지보수가 용이하도록 하였다. 자동 승하강장치를 장착한 태양집광판을 사용한 가로등을 활용함으로써 태양집광판의 집광효율 향상에 따른 가로등의 조명효율을 향상시킬 수 있고, 가로등의 유지보수 비용 절감 및 교체작업 시간 동안의 교통 정체현상 등을 예방할 수 있을 것으로 기대된다. In this paper, an automatic escalator system is manufactured for concentrate lighting efficiency and maintenance improvement technology of street light used a solar condenser. It can be linked with street light used a solar condenser, improved concentrate lighting efficiency by regulating concentrate light angle of a solar condenser. It can be remove and attach to solar condenser and street light. By developing street light used a solar condenser with an automatic escalator system, the lighting efficiency of street light and the concentrate lighting efficiency of solar condenser are High. The maintenance fee of street light significantly reduce and traffic congestion during working hours of street light is prevent.

용융환원으로서의 Romelt Process

박현서,이환노,변창수,허남석,반봉찬 대한금속재료학회 ( 구 대한금속학회 ) 1994 금속제련 학술회의 Vol.- No.-

개의 고관적 이형성 치료를 위한 변형 3종 골반 절골술의 적용

김영삼,임지혜,정창수,변예은,金谷 友,永岡 勝好,권오경 한국임상수의학회 2005 한국임상수의학회지 Vol.22 No.4

objective of this study was to evaluate the effects of modified triple pelvic osteotomy (TPO). The procedures of modified TPO were composed of two iliac osteotomies and a pubic symphysiotomy at a time. Medical records of modified TPO treatment on 36 dogs and of unilateral TPO on 7 dogs were reviewed on the basis of signalment, body weight, operation time, healing time of osteotomy sites and complications from October 2002 to September 2004. The values of clinical status and hip dysplasia, Norberg angle, percentage of femoral head coverage and pelvic diameter from radiographs taken preoperative, immediately postoperative, 2, 4, 8, 12 and 24 weeks after operation, respectively, were measured. In unilateral TPO, the dogs could start standing without assistance from 3.0±1.0 days and walking from 8.3±0.6 days (n=3). Mean clinical grade before and 24 weeks after surgery were 2.2±0.42 (n=6) and 3.5±0.7 (n=2), respectively. Mean operation time was 107.3±38.9 minutes (n=4). In modified TPO, the dogs were seen to start standing without assistance from 4.9±3.7 days and walking from 7.3±4.8 days (n=25). Mean clinical grade before surgery and 24 weeks after surgery were 2.3±1.5 (n=27) and 3.2±0.7 (n=9), respectively. Postoperative clinical grade significantly improved against preoperative clinical grade (P<0.01). Mean operation time was 143±42.8 minutes (n=24). This was shorter than time for twice unilateral TPO. By comparison with preoperative values, postoperative mean radiographic grade, percentage of femoral head coverage and Norberg angle measured at the recheck time point significantly increased (P<0.01). Mean postoperative pelvic diameter was significantly largerthan preoperative pelvic diameter in modified TPO (P<0.01) but not in unilateral TPO. These results indicated that modified TPO was effective technique for the treatment of hip dysplasia in dogs.

위에서 발생한 선암과 미만성 거대 B세포 림프종의 동시성 중복암

박수역 ( Soo Yuck Park ),은창수 ( Chang Soo Eun ),변영상 ( Young Sang Byun ),윤지영 ( Ji Young Yoon ),전용철 ( Yong Cheol Jeon ),한동수 ( Dong Soo Han ),손주현 ( Joo Hyun Sohn ),오영하 ( Young Ha Oh ) 대한소화기학회 2011 대한소화기학회지 Vol.57 No.2

The simultaneous occurrence of primary gastric lymphoma and adenocarcinoma is rarely reported. We here report a case of synchronous double primary tumor of advanced gastric cancer and diffuse large B cell lymphoma. A 65-year-old woman underwent an esophagogastroduodenoscopy for the evaluation of abdominal discomfort of two months` duration. The endoscopic examination showed an ulcerating tumor in the gastric antrum and thickened folds in the fundus and the microscopic examination revealed an adenocarcinoma in the antrum and a diffuse large B-cell lymphoma in the fundus. She has had total gastrectomy and CHOP chemotherapy with rituximab. Since the cases of synchronous double primary gastric tumors have been increased on the recent medical advances, when a gastric tumor is detected for the endoscopic examination, an endoscopist has to make every endeavor not to miss another tumor in the stomach. (Korean J Gastroenterol 2011;57:115-119)

이방향성 형상기억합금을 이용한 공동 주택용 방화 댐퍼 설계 연구

황성태,이찬희,장진수,변창수,히식수렝,이상욱 순천향대학교 산업기술연구소 2022 순천향 산업기술연구소논문집 Vol.28 No.2

The purpose of this paper is to redesign, compare, and study using bi-directional shape memory alloy spring to compensate for the shortcomings of the existing fire damper performance. Through the spring constant measurement experiment, using the difference in force between the coil spring and the shape memory alloy spring, the damper closes when the set temperature is reached, and opens again when the temperature is lowered. In addition, the internal structure was redesigned through smoke leakage experiments. As a result, semi-permanent usable dampers were modeled.