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위에서 발생한 선암과 미만성 거대 B세포 림프종의 동시성 중복암
박수역 ( Soo Yuck Park ),은창수 ( Chang Soo Eun ),변영상 ( Young Sang Byun ),윤지영 ( Ji Young Yoon ),전용철 ( Yong Cheol Jeon ),한동수 ( Dong Soo Han ),손주현 ( Joo Hyun Sohn ),오영하 ( Young Ha Oh ) 대한소화기학회 2011 대한소화기학회지 Vol.57 No.2
The simultaneous occurrence of primary gastric lymphoma and adenocarcinoma is rarely reported. We here report a case of synchronous double primary tumor of advanced gastric cancer and diffuse large B cell lymphoma. A 65-year-old woman underwent an esophagogastroduodenoscopy for the evaluation of abdominal discomfort of two months` duration. The endoscopic examination showed an ulcerating tumor in the gastric antrum and thickened folds in the fundus and the microscopic examination revealed an adenocarcinoma in the antrum and a diffuse large B-cell lymphoma in the fundus. She has had total gastrectomy and CHOP chemotherapy with rituximab. Since the cases of synchronous double primary gastric tumors have been increased on the recent medical advances, when a gastric tumor is detected for the endoscopic examination, an endoscopist has to make every endeavor not to miss another tumor in the stomach. (Korean J Gastroenterol 2011;57:115-119)
타카야수 동맥염의 진단과 치료 과정에서 Positron-Emission Tomography의 역할
박세우 ( Se Woo Park ),이창화 ( Chang Hwa Lee ),김근호 ( Gheun Ho Kim ),정명호 ( Myung Ho Jeong ),박수역 ( Soo Yuck Park ),송순영 ( Soon Yeong Song ),최윤영 ( Yun Young Choi ),강종명 ( Chong Myung Kang ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.1
Takayasu arteritis is a nonspecific granulomatous inflammatory arteriopathy of unknown cause that results in occlusive obliteration and less commonly aneurysmal degeneration of large and medium-sized elastic arteries. The diagnosis of Takayasu arteritis and the assessment of its progression and extent remain challenging, especially in patients presenting with a constellation of non-specific symptoms and laboratory tests. The standard diagnostic procedures include biopsy, arteriography, sonography, and magnetic resonance angiography. However, these procedures are invasive or largely operator-dependent, and document only morphological changes such as stenosis, occlusion and aneurysmal transformation which mainly occur in late stages of the disease. On the other hand, Positron-emission tomography is an operator-independent, non-invasive metabolic imaging modality which plays a major role in diagnosis of nonspecific inflammatory diseases. We report a case in which Positron-emission tomography was applied to the detection of Takayasu arteritis and assessment of its disease progression.
김태환 ( Tae Hwan Kim ),김은경 ( Eun Kyoung Kim ),이강원 ( Kang Won Lee ),정경희 ( Kyong Hee Jung ),백승삼 ( Seung Sam Paik ),박수역 ( Soo Yuck Park ),황덕원 ( Deok Won Hwang ) 대한류마티스학회 2011 대한류마티스학회지 Vol.18 No.1
Etanercept is a soluble receptor fusion protein that inhibits tumor necrosis factor-alpha(TNF-α). The receptor is used widely in the treatment of ankylosing spondylitis, rheumatoid arthritis, sarcoidosis and other indications. For sarcoidosis, it potentially suppresses granuloma formation with TNF-α blocking. On the other hand, recent studies have suggested that paradoxical sarcoidosis can be induced by TNF-α antagonists in some cases. A 42-yearold woman, who was treated with etanercept due to ankylosing spondylitis for 5 years, was admitted because of right suprahilar lymphadenopathy on chest radiography. Chest computed tomography revealed an enlargement of supraclavicular, paratracheal, mediastinal lymph nodes. She was diagnosed with sarcoidosis on the supraclavicular lymph node biopsy, which was non-caseating epithelioid cell granuloma and excluded from similar diseases. She was treated for sarcoidosis with prednisolone instead of etanercept.