공동 발의안들을 바탕으로 20대 국회의원 네트워크 분석 시스템 구축

박유민(Yu-Min Park),이상훈(Sang-Hoon Lee),한치근(Chi-Geun Han) 한국정보과학회 2018 한국정보과학회 학술발표논문집 Vol.2018 No.12

선박 엔진의 배출 미세먼지 저감을 위한 정전매연여과장치 실증 평가

박인용(Inyong Park),김영훈(Younghun Kim),김상복(Sang Bok Kim),이건희(Gunhee Lee),홍기정(Kee-Jung Hong),신동호(Dongho Shin),한방우(Bangwoo Han) 한국연소학회 2022 KOSCOSYMPOSIUM논문집 Vol.2022 No.11

알루미늄이 수생동물에 미치는 독성에 관한 소고

박찬진 ( Chan Jin Park ),김대한 ( Dae Han Kim ),한상호 ( Sang Ho Han ),계명찬 ( Myung Chan Gye ) 한국환경생물학회 2014 환경생물 : 환경생물학회지 Vol.32 No.4

알루미늄은 폐광산 침출수, 산업폐수, 생활하수 등을통해 수계로 유입되어 수생생물에 농축되고 독성을 유발할 수 있다. 최근 다양한 수생생물에서 알루미늄의 독성에 관한 보고가 증가하고 있지만 오염현황 및 생태독성에 대한 연구가 많이 이뤄지지 않았다. 본 소고에서는 수서무척추동물, 어류, 양서류에서 알루미늄의 독성자료를 고찰함으로써 잔류량 가이드라인 설정의 필요성과 알루미늄의 수생태독성 분석전략을 제언하고자 하였다. 다양한 형태의 알루미늄화합물이 수생동물에서 1차적으로 아가미기능을 방해하여 생존을 위협하고 세포독성,유전독성, 산화적스트레스, 내분비계교란, 생식교란, 대사교란, 항상성교란 등의 독성효과가 있는 것으로 확인되었다. 특히, 산성조건에서 환경잔류농도 수준의 알루미늄화합물은 어류에서 호르몬농도 변화를 유발하였다. 알루미늄은 산성 및 염기성 조건에서 용해도가 증가하기 때문에 국내의 폐광산 인근의 산성 수계 뿐 아니라 조류대발생에 의해 pH가 상승하는 호수나 강에서도 알루미늄의 독성효과가 나타날 것으로 사료된다. Aluminum flows into the river from the abandoned mine leachate, industrial wastewater, and sewage and is responsible for acute toxicity in aquatic organisms. Recently, the number of reports have indicated the increased toxicity in a variety of aquatic organisms’ due to the aluminum toxicity. In this study, we reviewed the toxicity of aluminum on aquatic invertebrates, fishes and amphibians and suggested the guideline for management of aluminum residues in aquatic environment and strategies for aluminum toxicity evaluation. In aquatic animals aluminum complexes evoke gill dysfunction primarily, the cytotoxicity, genotoxicity, oxidative stress, disruption of endocrine function, reproductive success, metabolism and homeostasis. Notably, at environmentally relevant concentration, aluminum complex can alter the hormone levels in fish in acidic condition. Further, since the solubility of aluminum is higher in the acidic and basic conditions, thus it is likely that the toxic effects of aluminum may not only occur in acidic water near the abandoned mines but also in lakes and rivers, where pH is raised by algal bloom.

FIR과 FGR 기법이 적용된 메탄-공기 대향류 확산화염에서 화염구조와 NO 배출 연구

박정(Jeong Park),권오붕(Oh Boong Kwon),김세원(Sewon Kim),이창엽(Changyeop Lee),길상인(Sang-In Keel),윤진한(Jin-Han Yun),임인권(In Gweon Lim) 한국연소학회 2016 한국연소학회지 Vol.21 No.1

Flame characteristics and NO emission behavior in CH4/air-air premixed counterflow flames with applying FIR and FGR with CO₂ and H₂O were investigated numerically by varying the ratios of FIR and FGR as well as global strain rate. Chemical effects of added CO₂ and H₂O via FIR and FGR were analyzed through comparing flame characteristics and NO behaviors from real species(CO₂ and H₂O) with those from their artificial species(XCO₂ and XH₂O) which have the same thermochemical, radiative, and transport properties to those for the real species. The results showed that flame temperature and NO emission with FIR varied much more sensitively than that with FGR. Those varied little irrespective of adding CO₂, H₂O, and their artificial species to the fuel stream via FIR. However, Those were varied complicatedly by chemical effects of added CO₂ and H₂O via FGR. Detailed analyses for them were made and discussed.

디젤 선박에서 배출되는 미세먼지 저감을 위한 정전매연여과장치 개발 및 선박 실증 적용에 대한 연구

박인용(Inyong Park),김영훈(Younghun Kim),김상복(Sang Bok Kim),이건희(Gunhee Lee),홍기정(Kee-Jung Hong),허기준(Ki Joon Heo),신동호(Dongho Shin),한방우(Bangwoo Han) 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.5

대시호탕가미방(大柴胡湯加味方)이 고혈압(高血壓) 및 고지혈증(高脂血症)에 미치는 영향(影響)

박치상,박창국,한승동,박순달,Park, Chi-Sang,Park, Chang-Gook,Han, Seung-Dong,Park, Soon-Dal 대한한방내과학회 1998 大韓韓方內科學會誌 Vol.19 No.2

The aim of the study was the experiment of the effect that Kami-Daesihotang had on the essential hypertension and hyperlipidemia. Rats were orally administered with Kami-Daesihotang for 30days and the constituent of the plasma and serum were analysed at the 10th, 20th and 30th day from the first day of experiment, respectively. The heart rate, blood pressure, plasma renin activity, plasma level of aldosterone, catecholamine, sodium and angiotensin II were measured after an oral administration of Kami-Daesihotang in SHR. In addition, serum levels of total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol and total lipid were measured with cholesterol-fed rats. The results were summarized as following ; 1. Single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang remarkably decreased the blood pressure in SHR. 2. Double-dosage Kami-Daesihotang were recognized as having the effect on the decreased of the pulse rate in SHR. 3. Plasma renin activity was significantly decreasd in SHR after single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang treatment. 4. Double-dosage Kami-Daesihotang considerably reduced the plasma angiotensin level in SHR. 5. Noticeable decreased of plasma norepinephrine level was showed in SHR, after single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang treatment. 6. Single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang noticeable reduced body weight in hyperlipidemia rats which had fed with 1% cholesterol. 7. Single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang had a significantly decreasing effect on serum total cholesterol in hyperlipidemia rats which had fed with 1% cholesterol. 8. Serum triglyceride level was importantly decreased in hyperlipidemia rats which had fed with 1% cholesterol, after single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang treatment. 9. Remarkable decreased of serum low density lipoprotein cholesterol level was found in hyperlipidemia rats which had fed with 1% cholesterol, after single-dosage Kami-Daesihotang & double-dosage Kami-Daesihotang treatment. 10. Double-dosage Kami-Daesihotang was showed a significantly decreasing effect on serum total lipid level in hyperlipidemia rats which had fed with 1% cholesterol. 11. Single-dosage Kami-Daesihotang noticeably reduced organ weight of liver, kidney, spleen and testis in hyperlipidemia rats which had fed with 1% cholesterol. Double-dosage Kami-Daesihotang significantly decreased organ weight of liver, kidney and spleen in hyperlipidemia rats. These Findings suggest a possible anti-hypertensive and hyperlipidemic effect of Kami-Daesihotang.

차선 유지 보조 시스템으로 인해 발생하는 이질감의 계측에 대한 연구

박규동(Kyudong Park),곽지영(Jiyoung Kwahk),한성호(Sung H. Han),송민석(Minseok Song),최동구(Dong Gu Choi),장혜지(Hyeji Jang),김도현(Dohyeon Kim) 대한인간공학회 2018 大韓人間工學會誌 Vol.37 No.4

Objective: The objective of this study is to investigate the intrusive feeling caused by a Lane Keeping Assistance System (LKAS) and measure it objectively through the sensor log data of a vehicle. Background: LKAS, one of the Advanced Driver Assistance System (ADAS), directly intervenes in the steering wheel control to assist the driver to keep the lane. Due to the torque generated by the LKAS, the driver has a different and undesirable feeling from a usual situation, which can affect the driving experience. Nevertheless, the performance of the LKAS in most studies focused only on how well the system keeps the lane. Method: Through an actual driving test using a test vehicle equipped with an LKAS, two ADAS experts and two human factor experts observed the intrusive feeling while collecting sensor log data at the same time. After the types of the intrusive feeling were classified, variables that could account for the feeling were derived. Then, this study compared the data collected from the vehicle with and without the intrusive feeling. Results: Three types of the intrusive feeling were observed: abrupt lateral change, steering wheel vibration, and heavy steering. The lateral speed (LS), the high-pass filtered steering angle (FSA), and the interrupt torque (IT) were then derived as the variables that could explain each feeling, respectively. It is found that the patterns of the derived variables are different in driving with and without the intrusive feeling. Conclusion and Application: The intrusive feeling found in this study can be used as a performance index in the development stage of the LKAS. It will be helpful to systematically reduce the intrusive feeling.

소셜 네트워크 구성을 위한 모바일 컨텍스트 설계 및 수집

박한샘(Han-Saem Park),정태민(Tae-Min Jung),조성배(Sung-Bae Cho) 한국정보과학회 2009 한국정보과학회 학술발표논문집 Vol.36 No.2B

최근 스마트폰이나 PDA와 같은 모바일 디바이스가 널리 보급되었으며, 또한 개인화 장비기술이 발달하면서 모바일 디바이스가 카메라, MP3 플레이어 등 다양한 기능을 포함하게 되었다. 이와 함께 대부분의 사용자가 보유하고 있는 모바일 디바이스는 사용자가 항상 휴대하고 다니며, 여러가지 센서를 포함하고 있어 사용자의 다양한 컨텍스트 정보를 수집하기에 매우 유용한 도구가 되었다. 본 논문에서는 이러한 모바일 디바이스를 이용하여 사용자의 다양한 컨텍스트를 수집하기 위한 방법을 제시한다. 수집된 모바일 컨텍스트는 다양한 연구를 위해 활용될 수 있는데, 본 논문에서는 모바일 소셜 네트워크 구성을 주요 목적으로 하였으며 설계 또한 이러한 목적을 고려하여 이루어졌다. 마지막으로 제시된 방법을 통해 실제로 수집된 컨텍스트를 소개하고, 향후 어떤 연구를 위해 활용될 수 있는지를 기술한다.

길경 Saponin이 고지방식이를 한 흰쥐의 혈청, 간장 및 분변 지질 함량에 미치는 영향

박무희(Mu-Hee Park),이영주(Young-Ju Lee),황성원(Sung-Wong Hwang),한준표(Jun-Pyo Han),배만종(Man-Jong Bae) 한국식품영양과학회 1994 한국식품영양과학회지 Vol.23 No.4

6주간 고지방식이를 섭취한 흰쥐에 있어서 길경 saponin이 지방 축적 억제와 대사에 미치는 영향을 검토하고자 혈청과 간장 및 분변 중 지방 성분을 생화학적으로 분석하여 다음과 같은 결과를 얻었다. 1. 혈청 및 간장중의 총지질, 총콜레스테롤 및 중성지방 함량은 길경 saponin군이 대조군에 비하여 유의한 감소를 보였다. 2. 분변 중 총지질 및 총콜레스테롤 함량은 대조군과 비교할 때 길경 saponin군이 다소 배설이 증가되었으나, 유의성은 인정되지 않았다. This study was conducted to investigate the effect of Platycodi radix saponin (PRS) on the reduction of lipid status in rats fed on high fat diet for 6 weeks after which lipid contents were measured in serum, liver and feces. The results obtained from this study are as follows; That the levels of total lipid, total cholesterol and triglyceride in serum and liver were significantly lower in the PRS group as compared with the control group. The contents of total lipid and total cholesterol excreted in the feces were tended to be slightly increase in PRS group compared to the control group, which were not significant.

신장 ; ABO 혈액형 부적합 신장이식 환자에서 혈연 간 신장이식과 비혈연 간 신장이식의 성적 비교

박우영 ( Woo Yeong Park ),한승엽 ( Seung Yeup Han ),황은아 ( Eun Ah Hwang ),박성배 ( Sung Bae Park ),박의준 ( Uijun Park ),김형태 ( Hyung Tae Kim ),조원현 ( Won Hyun Cho ) 대한내과학회 2014 대한내과학회지 Vol.87 No.6

목적: 신장이식은 말기 신부전 환자의 치료에 있어 가장 효과적인 신대체 요법이다. 과거 ABO 혈액형 적합 신장이식에서 혈연 공여자 신장이식이 비혈연 공여자 신장이식보다 성적이 좋다고 보고 되었으나 최근에는 성적에 차이가 없다고 보고되고 있다. ABO 혈액형 부적합 신장이식에서 혈연간 신장이식과 비혈연 간 신장이식 성적을 비교하였다. 방법: 2011년 1월부터 2013년 8월까지 ABO 혈액형 부적합 신장이식 19예가 후향적으로 분석되었다. 혈연 간 신장이식은 8예(부모-자식 간 7예, 형제간 1예), 비혈연 간 신장이식은 11예(배우자 간 11예)였다. ABO 혈액형 부적합 신장이식에서 혈연 간 신장이식군과 비혈연 간 신장이식군의 환자 및 이식 신장 생존율, 급성 거부반응, 이식 신장 기능, 합병증에 대해 조사하였다. 결과: Kaplan-Meier 분석에 따라 혈연 간 신장이식군에서 추적 기간 동안 환자 생존율 및 이식 신장 생존율은 각각 87.5%, 87.5%였고 비혈연 간 신장이식군에서 모두 100%였다. 급성 거부반응, 이식 신장 기능, 내외과적 합병증은 양군간에 의미 있는 차이가 없었다. 결론: ABO 혈액형 부적합 신장이식에서 혈연 간 신장이식과 비혈연 간 신장이식 단기 성적의 차이가 없었다. 국내 비혈연 간 신장이식의 대부분은 배우자 간 신장이식으로 배우자는 ABO 혈액형 부적합 신장이식의 주요 공여자가 될 수 있을 것이다. Background/Aims: Kidney transplantation (KT) is the best treatment for end-stage renal disease patients. Although previous studies have demonstrated that the clinical outcome following living related (LR) KT is better than that following unrelated (LUR) KT in ABO-compatible KT recipients, recent studies showed no differences in clinical outcomes between the two treatments. In this study, we compared the clinical outcomes of LR and LUR KT in ABO-incompatible KT recipients. Methods: From January 2011 to August 2013, 19 cases of ABO-incompatible KT were analyzed retrospectively. Eight kidneys (7 cases of parent-offspring and 1 case of siblings, Group 1) were donated from living-related donors and 11 (all spousal donors, Group 2) from living-unrelated donors. We investigated patient survival, graft survival, acute rejection, graft function, and complications. Results: On Kaplan-Meier analysis, patient and graft survival during follow-up were 87.5% and 87.5% in Group 1, both were 100% in Group 2. Acute rejection, graft function, and medical and surgical complications were not significantly different between the two groups. Conclusions: The short-term clinical outcomes between LR and LUR KT in ABO-incompatible KT recipients were equivalent. Most domestic cases of LUR KT are from spousal donors and the spousal donor will be a major donor in ABO-incompatible KT patients. (Korean J Med 2014,87:698-704)