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      • KCI등재

        미반응 레진단량체가 우식유발성 세균의 활성에 미치는 영향

        박성규,김화숙,유소영,한진주,국중기,이난영,이상호,이창섭,Park, Seung-Kyu,Kim, Hwa-Sook,You, So-Young,Han, Jin-Ju,Kook, Joong-Ki,Lee, Nan-Young,Lee, Sang-Ho,Lee, Chang-Seop 대한소아치과학회 2003 大韓小兒齒科學會誌 Vol.30 No.4

        본 연구는 복합레진에서 유출된 수용성 미반응단량체가 치아우식발생 원인균인 S. mutans와 S. sobrinus의 증식과 비수용성 glucan의 형성능에 미치는 영향을 평가하고자 광중합 레진전색제를 10분, 1시간, 12시간 24시간 물에 침잠시켜 레진화학물을 용출한 후 1/2, 1/4, 1/8의 농도로 첨가한 BHI broth 또는 BHI-YS에서 세균을 24시간 배양한 후, 흡광도를 측정하며 다음과 같은 결과를 얻었다. 1. S. mutans의 성장률은 10분 용출액의 1/4 농도에서 성장조절군에 비해 현저히 감소된 반면 1/2, 1/8 농도에서는 증가하는 경향을 보였으며, 1시간 용출액은 S. mutans의 성장을 촉진하였으며, 특히 1/2, 1/4 농도에서 성장률이 높았다. 또한 12시간, 24시간 용출액은 S. mutans의 성장에 영향을 주지 않았다. 2. S. sobrinus의 성장률은 10분 용출액의 1/4 농도에서는 현저히 억제되었으나, 1시간, 12시간 24시간 용출액은 모든 농도에서 S. sobrinus의 성장에 영향을 주지 않았다. 3. 레진용출액은 성장조절군에 비해 S. mutans의 총성장을 촉진하였으나 S. sobrinus의 총성장은 억제하였다. 4. S. mutans의 비수용성 glucan 형성능은 성장조절군에 비해 촉진되었으며, 특히 10분 용출액의 1/4농도에서 현저하였으며, 모든 용출액의 1/8농도에서는 glucan의 형성능은 감소하였다. 5. S. sobrinus의 비수용성 glucan의 형성능은 10분용출액의 1/4 농도를 제외하고는 성장대조군에 비해 감소하였다. 6. S. mutans의 비수용성 glucan의 총형성량은 S. sobrinus에서보다 약 3배 정도 높았다. The aim of this study was to investigate the effect of composite resin components on proliferation and glucan synthesis by cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus. Light curing pit and fissure sealant was chosen for evluation. Specimens were eluted in deionized water for 10 minutes, 1, 12, and 24 hours. Extracts of specimens were diluted into 1/2, 1/4, and 1/8 with addition of BHI broth and BHI-YS. Bacteria were cultured in media included eluted components, and measured optical density($A_{600}$). The following results were obtained 1. 1/4 concentration of elutes for 10 minutes significantly inhibited the proliferation of S. mutans, whereas 1/2, 1/8 concentration of elutes stimulated it. Also, exacts, especially 1/2, 1/4 concentration, for 1 hours stimulated it. But exacts for 12, 24 hours had not effects on the proliferation of S. mutans. 2. 1/4 concentration of elutes for 10 minutes inhibited growth of S. sobrinus, whereas extracts for 1, 12, 24 hours had not effects on the proliferation of S. sobrinuss. 3. Extracts from composite resin stimulated total growth of S. mutans more than growth control group, where as inhibited it of S. sobrinus. 4. Extracts from composite resin, especially 1/4 concentration of it for 10 minutes increased the formation of water insoluble glucan of S. mutans. But elutes for 1, 12, 24 hours, and 1/8 concentration of it for 10 minutes inhibited it. 5. Except 1/4 concentration of elutes for 10 minutes, extracts decreased the formation of water insoluble glucan of S. sobrinus. 6. Total amount of formated glucan was 3-fold higher in S. mutans than in S. sobrinus.

      • KCI등재

        Glass Ionomer시멘트에 의한 상아질구조변화에 관한 주사전자현미경적 연구

        박성규,우이형,최대균,최부병,박남수,Park, S.K.,Woo, Y.H.,Choi, D.K.,Choi, B.B.,Park, N.S. 대한치과보철학회 1987 대한치과보철학회지 Vol.25 No.1

        This study was designed to investigate the pulpal effects of the glass ionomer cement. (Lining cement, G-C Co. Japan) For this purpose, 10 cats were selected, and Class V cavities were prepared on canines of the cats. One experimental group was filled with glass ionomer cement and the other group was filled with zinc phosphate cement . (G-C Co, Japan) The animals of the experimental and control group were sacrificed at 1,2,3,4,6, weeks after the experiment. For comparison of reparative dentin formation pattern in direction of the pulpal and fractured lateral surface, each of them was observed with scanning electron microscope. The findings led to the following conclusions; 1. Reparative dentin of the glass ionomer cement and zinc phosphate cement filling groups were formed on the internal surface of dentin as the shape of hemispherical and spherical with a rough surface. 2. Some of reparative dentin of the glass ionomer cement filling group was started to form at 1 week after experiment, and at 6 weeks after experiment, it had been increased gradually in number and size. 3. Reparative dentin of zinc phosphate cement filling group was formed vigorously, however, gradually was decreased in number and size, and disappeared at 6 weeks after experiment. 4. During the formation of reparative dentin, peritubular dentins were indistinguishable. 5. The diameter of dentinal tubules of reparative dentin has been decreased, during the reparative dentin formed, and it became very irregularly at 6 weeks after experiment.

      • KCI등재

        용양山 마그네사이트鑛石의 하燒 특성

        박성규,박진태,이후인,최영윤,Park, Hyung-Kyu,Park, Jin-Tae,Lee, Hoo-In,Choi, Young-Yoon 한국자원리싸이클링학회 2005 資源 리싸이클링 Vol.14 No.1

        마그네슘은 자동차 엔진 경량화재료, 휴대폰케이스 등 기능성 경량재료로서의 용도개발과 함께 수요가 증가하고 있다. 본 연구에서는 북한 용양산 마그네사이트 광석을 하소하여 마그네슘 제련의 첫 단계 산물인 산화마그네슘을 제조하고자 하였다. 시료 마그네사이트 품위는 MgO가 약 45%이고, 불순물로서는 SiO$_2$, CaO, Fe$_2O_3$와 Al$_2O_3$를 소량 함유하였다. 광석의 하소 전에 파쇄, 분급을 행한 다음 열분석을 통하여 하소온도 범위를 정하였다. 하소 실험은 45~75 ${\mu}m$ 크기의 시료 분말을 사용하여 600-900$^{\circ}C$ 범위에서 하였으며, 온도에 따른 하소율 변화가 하소가 진향되는 동안의 입자형상을 조사하였다. 마그네사이트의 하소 온도는 750$^{\circ}C$ 정도가 적절하였으며, 이 온도에서 30분간 하소함으로써 99% 이상의 하소율을 달성하고, 약 95 wt% 순도의 산화마그네슘을 제조할 수 있었다. Worldwide magnesium market has been considerably growing recently due to adoption as light materials for automobile engines and electronic devices such as mobile phones. In this study, it is to prepare magnesium oxide, which is the first-step product in smelting of magnesium from the ore, using magnesite of Yongyanag mines in North Korea as raw ores. MgO grade of the magnesite was about 45 wt%, and SiO$_2$, CaO, Al$_2O_3$ and Fe$_2O_3$ were contained as impurities. The sample ore was crushed, classified and thermally analyzed to determine its calcination temperature. The sample of 45-75 ${\mu}m$ size was calcined at 600-900$^{\circ}C$, and effect of temperature on calcination and change of the particle shape was investigated. Optimum temperature of the calcination was about 750$^{\circ}C$, and 30 minutes was sufficient to obtain over 99% conversion. The purity of the calcined MgO was about 95 wt%.

      • KCI등재

        A Study on the Transformation of Baicalin or Antibacterial, Antitumor Effect of the Active Ingredients in Scutellariae Radix

        박성규,안덕균,우은란,박현미,Park, Seong-Kyu,Ahn, Duk-Kyun,Woo, Eun-Ran,Park, Hyun-Mee The Society of Korean Medicine 1997 대한한의학회지 Vol.18 No.1

        Scutellariae Radix has been widely used as oriental herbal medicine for the treatment of bacterial infections in the respiratory or the gastrointestinal tract. In partition experiment for better understanding of herbal medicine with various solvents, baicalein or wogonin have more hydrophobic characteristics than baicalin or wogonoside. Unexpectedly, methylene chloride could extract more for baicalin or wogonoside over other active ingredients. New compound from baicalin is discovered casting frointier area on herbal medicine in the future. Application study with new molecule hydrolyzed from baicalin is on the way for better treatment of the patient against specific disease. The baicalin modified with reaction has been shown weak antibacterial activity against Streptococcus pyogenes 308A and Pseudomonas aeruginosa 1771. The minimum inhibitory concentration (MIC) of the baicalin modified compound against those strains were about $600\;{\mu}g/mL$, respectively. In vitro antitumor experiment, $EC_{50}$ of baicalin modified with reaction was more than $300\;{\mu}g/mL$ and $EC_{50}$ of baicalein was $100\;{\mu}g/mL$. Among these compounds, baicalin exhibited high level of antitumor activity. $EC_{50}$ of baicalin was less than $33.3\;{\mu}g/mL$.

      • SCOPUSKCI등재

        Cryptand 21 합성수지를 이용한 금속 이온의 흡착 및 분리에 관한 연구

        박성규,김준태 ( Seong Kyu Park,Joon Tae Kim ) 한국공업화학회 1995 공업화학 Vol.6 No.6

        1%, 2%, 및 20% 다리결합도의 클로로메틸화된 1,4-디비닐벤젠에 cryptand 21 거대고리 리간드를 치환반응으로 결합시키고, 이들 수지로부터 흡착에 미치는 pH, 수지의 다리결합도 그리고 금속 이온 농도의 영향에 대하여 조사하였다. 금속 이온들은 pH 3 이하에서는 잘 흡착되지 않았으나 pH 4 이상에서는 큰 흡착률을 보였으며 금속 이온들의 흡착 평형시간은 약 2시간 이었다. 한편, 에탄올 매질에서의 흡착선택성은 UO₂^(2+)>Ni^(2+)>Ce^(3+)이었으며 1% 다리결합도의 수지를 충진시킨 컬럼에 흡착시킨 후 용리액으로 pH 2.5 HNO₃을 사용하여 개별 분리가 가능하였다. Resins with cryptand 21 macrocyclic ligand attached to chloromethylated styrene-1,4-divinylbenzene by substitution reaction were prepared and the effect of pH, metal concentration and cross-linkage of the matrix on the adsorption for UO₂^(2+), Ni^(2+) and Ce^(3+) was investigated. The metal ion was not adsorbed on the resins pH range below 3 and above pH 4, fast adsorption behavior was showed. The resin selectivity determined in ethanol matrix was in increasing order UO₂^(2+)>Ni^(2+)>Ce^(3+). In addition, these metal ion could be separated on the column packed with 1% crosslinked resin by pH 2.5 HN₃ as an eluent.

      • 첨단영상제작장비 원리 및 응용사례

        박성규,이민기,최진성,Park, S.G.,Lee, M.G.,Choi, J.S. 한국전자통신연구원 2005 전자통신동향분석 Vol.20 No.4

        2004년, 개봉 39일만에 국내관객 1000만 명을 돌파하며 국내영화사상 신기록을 수립한 영화 ‘태극기 휘날리며’에선 사상 유례없는 10만여 명 이상의 피난 및 중공군 진격장면이 연출되었다. 그러나, 10만여 명이 나오는 장면을 찍기 위해 동원된 엑스트라는300여 명에 불과하다. 1982년작 영화 ‘간디’의 장례식에 동원된 30만 명의 엑스트라를 생각한다면 괄목할 발전이라 할 수 있다. 이와 같은 대규모 스펙터클 잠연이 영화에서 빈번히 활용될수록 첨단영상 장비에 대한 활용도는 제고될 것으로 예상된다.

      • KCI등재후보

        동의보감(東醫寶鑑) 월국환가미방(越鞠丸加味方)의 방제학적(方劑學的) 분석(分析)

        박성규,변성희,이병욱,김상찬,Park, Seong-Gyu,Byun, Sung-Hui,Lee, Byung-Wook,Kim, Sang-Chan 대한한의학방제학회 2011 大韓韓醫學方劑學會誌 Vol.19 No.1

        Objectives : This study was performed to analysis the composition of herbal formulations about a series of Wolgug-Hwan(WGH, formed by Gukchur-won and Sagung-san) in Dongeuibogam written by Heo Jun. Methods : The series of WGH in Dongeuibogam were selected by 'Prescription Lineage Graph' (http://164.125.206.43/PrescriptionLineageGraph.aspx) established by prof. Lee at Pusan National University. In the analysis of a series of WGH, we used some formulation books including classics. Results : Gaeuldogi-tang(GDT) is formed by WGH, Yeonggangchulgam-tang(YGT), Yugil-san (YIS) and Gungchul-san. Cheongul-san(CUS) is formed by WGH, Ijin-tang(IJT), YGT and Haegeum -hwan(HGH). Sosikcheongul-san(SCS) is formed by CUS and IJT. Jeungmiijin-tang(JIT) is formed by WGH, IJT, Sambaek-tang and Gyullyeonjichul-hwan. Sihoeokgan-tang(SET) is formed by WGH, Sihosogan-san(SSS) and Jigolpi-eum. Wolgukbohwa-hwan(WBH) is formed by WGH, Bohwa-hwan, Mokyangjichul-hwan and Hwangnyeon-tang(HNT). Chimsa-hwan(CSH) is formed by WGH, Injinho-tang(IHT), Yungmisamneung-hwan, Jeungmisamul-tang and Sinseongugi-tang. Conclusions : SCS, CUS, or JIT has been used frequently in case of phlegm-fire. These are formulated by the combination of WGH and IJT with Samseon-san or HGH or Jichul-hwan according to the special symptoms, respectively. SET which is formulated by WGH and SSS has been used in case of stagnation of liver-qi. GDT, WBH or CSH has been used in damp-heat. These are formulated by the combination of WGH with YIS, HNT, or IHT, respectively.

      • KCI등재

        시${\cdot}$공간적 고해상도 자동차 배출량 모형의 개발

        박성규,김신도,박기학,Park, Seong-Kyu,Kim, Shin-Do,Park, Ki-Hark 한국환경보건학회 2004 한국환경보건학회지 Vol.30 No.3

        Traffic represents one of the largest sources of primary air pollutants in urban area. As a consequence, numerous abatement strategies are being pursued to decrease the ambient concentration of pollutants. A characteristics of most of the these strategies is a requirement for accurate data on both the quantity and spatial distribution of emissions to air in the form of an atmospheric emission inventory database. In the case of traffic pollution, such an inventory must be compiled using activity statistics and emission factors for vehicle types. The majority of inventories are compiled using passive data from either surveys or transportation models and by their very nature tend to be out-of-date by the time they are compiled. The study of current trends is towards integrating urban traffic control systems and assessments of the environmental effects of motor vehicles. In this study, a model of vehicle emission calculation by using real-time traffic data was studied. Traffic data, which are required on a street-by-street basis, is obtained from induction loops of traffic control system. It is possible that characteristics of hourly air pollutants emission rates is obtained from hourly traffic volume and speed. An emission rates model is allocated with a high resolution space by using geographic information system (GIS). Vehicle emission model was developed with a high resolution spatial, gridded and hourly emission rates.

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