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박동엽,박애라,정은희,배재형,이국천,황보원,이민권 한국동물위생학회 2009 韓國家畜衛生學會誌 Vol.32 No.4
Porcine proliferative enteritis (PPE) is a transmissible gastroenteric disease caused by Lawsonia intracellularis. Clinically, PPE causes hemorrhagic diarrhea and sometimes death in growing pigs, but when the disease progresses to a chronic phase, the infected pig no longer displays significant symptoms. The purpose of the present studies were carried out to determine L. intracellularis in the pig farms and slaughter house, in Gyeongnam area. A survey of proliferative enteritis in pig was conducted using polymerase chain reaction (PCR) testing method, total 1,495 samples. PCR products showed a specific band at the 210bp, 329bp in the feces specimens and mucosal scraping specimens. Of 420 feces specimens, 113 (26.9%) were identified as positive to PPE. Of 1,075 mucosal scraping specimens, 109 (10.1%) were identified as positive to PPE. Of total 1,495 specimens, 222 (14.8%) were identified as positive to PPE.
경기도 일개 종합병원에서 Pro-Brain Natriuretic Peptide와 통상적 혈액검사 인자간의 상관성 조사
박동엽,김상수,성현호,박창은,Park, Dong Yeop,Kim, Sang-Su,Sung, Hyun Ho,Park, Chang-Eun 대한임상검사과학회 2020 대한임상검사과학회지(KJCLS) Vol.52 No.3
This study investigated retrospectively the correlation between the results of the N-terminal pro-brain natriuretic peptide (NT-proBNP) and a routine blood test using a hospital information system. The NT-proBNP is involved in the pathophysiology of heart failure. The results show that the relationship between age and NT-proBNP was significant (P<0.01) with a positive correlation (r=0.163). The peptide concentration showed a negative correlation between the total protein (r=-0.250) and albumin (r=-0.270), and a negative correlation between the erythrocyte count and hemoglobin and hematocrit (P<0.01). NT-proBNP had a positive correlation with neutrophils (r=0.227) and a negative correlation with lymphocytes (r=-0.236), showing significant results (P<0.01). NT-proBNP and creatinine showed a positive correlation (r=0.594, P<0.01), and it was the most influential factor according to multiple regression analysis (B=0.53, t=7.65). P<0.01). The concentrations of NT-proBNP and uric acid showed a positive correlation (r=0.180, P<0.05). Lactate dehydrogenase was observed as a factor affecting the NT-proBNP (B=0.20, t=3.28, P<0.01). This explanatory power had an influence of 43%. Therefore, the accurate test and related factors of the NT-proBNP have significant clinical value. 본 연구의 목적은 병원정보시스템을 활용하여 N-말단 프로-뇌 나트륨 이뇨 펩타이드(N-terminal pro-brain natriuretic peptide, NT-proBNP)의 결과와 통상적인 혈액검사와의 상관성을 후향적으로 조사하는 것이다. NT-proBNP는 심부전의 병태 생리학에 관여한다. 본 연구결과는 연령과 NT-proBNP의 관계는 양의 상관관계(r=0.163)로 통계적으로 유의하였다(P<0.01). NT-proBNP 농도는 총 단백질(r=-0.250)과 알부민(r=-0.270)은 음의 상관관계, 적혈구수와 혈색소 그리고 적혈구 용적률은 음의 상관관계로 나타난 결과로 나타났다(P<0.01). NT-proBNP는 호중구와 양의 상관관계(r=0.227)와 림프구는 음의 상관관계(r=-0.236)로 통계적으로 유의한 결과가 나타났다(P<0.01). NT-proBNP와 크레아티닌은 양의 상관관계로 나타났으며(r=0.594, P<0.01), 다중회귀분석결과 가장 영향을 미치는 인자로 관찰되었다(B=0.53, t=7.65, P<0.01). NT-proBNP와 요산의 농도는 양의 상관관계로 유의한 관계를 나타냈다(r=0.180, P<0.05). 젖산탈수소효소가 NT-proBNP에 영향을 미치는 인자로 관찰되었다(B=0.20, t=3.28, P<0.01). 이러한 설명력은 43%의 영향력을 나타내어 NT-proBNP의 정확한 검사와 관련인자들은 심장표지자로서 임상적 가치가 있는 것으로 사료된다.
Evelopment of a Practical Mechanistic-Empirical design Procedure for Flexible Pavements
박동엽,김형배,서영찬,Park, Dong-Yeob,Kim, Hyung-Bae,Buch, Neeraj,Suh, Young-Chan Korean Society of Road Engineers 2002 한국도로포장공학회 논문집 Vol.4 No.3
Design methods for new flexible pavements and overlays are in the transition from empirical to mechanistic approach, and many state highway agencies trend to move toward the adoption and use of mechanistic-empirical (M-E) design in new constructions and rehabilitations of flexible pavements. Hence, the Michigan Department of Transportation (MDOT) decided to develop a M-E flexible pavement design procedure, in which major pavement distresses such as fatigue cracking and rutting are employed as indicators of the serviceability of a flexible pavement. The main concept of the developed design procedure is that a designed pavement that is supposed to carry a certain number of traffic must satisfy designated thresholds of rut depths and fatigue lives during a service period. For the M-E design procedure, transfer functions were developed to predict rut-depths and fatigue lives. These functions related the pavement responses to pavement performance. For validation, three current new flexible pavement design cases were obtained from the MDOT. In these cases, asphalt concrete (AC) layer thicknesses determined by the suggested M-E procedure compare favorably with those determined by the current MDOT design practice that is based on AASHTO design guide. This finding implies that the suggested Michigan M-E flexible pavement design procedure can provide a good opportunity to improve the current design practice. 현재 도로 설계는 기존의 경험적인 설계법에서 역학적인 설계법으로 바뀌고 있는 추세이다. 이러한 전환기에서 세계 많은 도로국들은 역학적-경험적인 도로 설계법을 개발하고 있고 혹은 이미 채택하여 적용하고 있다. 이에 실제 미국 미시간 도로국에서 나온 자료를 바탕으로 역학적-경험적 설계법을 개발하였다. 이 역학적-경험적 설계법의 연결 함수 (transfer function)로 사용될 소성 변형 예측 모델과 피로 균열 예측 모델도 함께 개발되었다. 여기서는 이 설계법을 개발하는데 사용된 자료와 예측 모델, 설계 알고리듬등이 소개된다. 이 설계법의 검증을 위해 기존의 경험적 설계법에 의한 설계와 새로 제시된 설계법에 의한 설계가 비교된다. 새로 설계된 설계법은 설계자 혹은 사용자가 도로 파손의 기준을 정량적으로 정함으로서 좀더 구체적으로 설계를 할 수가 있다.
균열보수용 폴리머 시멘트 복합체의 폴리머 종류에 따른 점도와 충전성에 관한 연구
박동엽 ( Park Dong-yeop ),권우찬 ( Kwon Woo-chan ),조영국 ( Jo Young-kug ) 한국건축시공학회 2022 한국건축시공학회 학술발표대회 논문집 Vol.22 No.2
The purpose of this study is to determine the viscosity of the polymer-cement composites(PCCs) for crack repair of RC structures and to investigate its compaction. According to the study on the viscosity and compaction property of PCCs for crack repair, the viscosity of PCCs varies greatly depending on the polymer type and polymer cement ratio, and by mixing silica fume into PCCs, appropriate viscosity and excellent flow can be controlled without separation of cement and water. As a result of this study, basic data on the viscosity, fluidity, and compaction properties of PCCs for crack repair of RC structure can be obtained.
박동엽 ( Dong Yeop Park ),박애라 ( Ae Ra Park ),정은희 ( Eun Hee Jung ),배재형 ( Jae Hyeong Bae ),이국천 ( Guk Cheon Lee ),황보원 ( Bo Won Hwang ),이민권 ( Min Kwon Lee ) 한국가축위생학회 2009 韓國家畜衛生學會誌 Vol.32 No.4
Porcine proliferative enteritis (PPE) is a transmissible gastroenteric disease caused by Lawsonia intracellularis. Clinically, PPE causes hemorrhagic diarrhea and sometimes death in growing pigs, but when the disease progresses to a chronic phase, the infected pig no longer displays significant symptoms. The purpose of the present studies were carried out to determine L. intracellularis in the pig farms and slaughter house, in Gyeongnam area. A survey of proliferative enteritis in pig was conducted using polymerase chain reaction (PCR) testing method, total 1,495 samples. PCR products showed a specific band at the 210bp, 329bp in the specimens of feces and mucosal scraping. Of 420 fecal specimens, 113 (26.9%) were identified as positive to PPE. Of 1,075 mucosal scraping specimens, 109 (10.1%) were identified as positive to PPE. Of total 1,495 specimens, 222 (14.8%) were identified as positive to PPE.
경남지역에서 도축우 및 돼지의 근육내 잔류항균물질 검색
박동엽 ( Dong Yeob Park ),양평섭 ( Pyeong Seob Yang ),남창우 ( Chang Woo Nam ),황보원 ( Bo Won Hwang ),김원규 ( Won Gyu Kim ),조상래 ( Sang Rae Jo ),김도경 ( Toh Kyung Kim ) 한국가축위생학회 2002 韓國家畜衛生學會誌 Vol.25 No.3
The present studies were carried out to determine antibiotics residues in pork and beef muscles by EEC-4-plate and HPLC. A total of 2,534 samples of pork muscles and 1,070 samples of beef muscles from slaughter houses were collected in Gyeongnam area from January to December, 2001. The results were summarized as follows; 1. Recovery rates of TCs, Sulfa drug, Penicillin G from fortified pork and beef muscles ranged as 68.79~98.24%, 78.21~94.58% and penicillin G 63.35~67.24% respectively, by HPLC. 2. Antibiotics residues were detected in 36 sample(1.42%) of pork muscles, 29 sample (2.71%) of beef muscles by EEC-4-plate. 3. Detection rate of antibiotic residues 14 samples(0.55%) and 26 samples(2.43%), in pork and beef muscles, respectively by HPLC. Concentration of residues in 22 sample(2.06%) of beef muscle were higher than tolerance level in korea. 4. Antibiotics detected were sulfamethazine(47.37%), tetracycline(15.79%), oxytetracycline(15.79%), penicillin G(15.79%), sulfamerazine(5.26%) in pork muscle samples and oxyteracycline(37.21%), penicillin G(30.23%), sulfamethazine(20.93%), tetracycline(4.65%), sulfamerazine(2.33%), sulfadimethoxine(2.33%), sulfaquinoxine(2.33%) in beef muscle samples.