백내장 수술 후 생긴 낭포황반부종에서의 유리체강내 트리암시놀론 주입술 일차치료 효과

김주연,김정목,유영주,김철구,조성원,이태곤.Joo Yeon Kim. MD. Joung Mok Kim. MD. Young Ju Lew. MD. PhD. Chul Gu Kim. MD. Sung Won Cho. MD. PhD. Tae Gon Lee. MD 대한안과학회 2012 대한안과학회지 Vol.53 No.3

Purpose: To report the clinical manifestations of intravitreal triamcinolone injection as a primary treatment method for patients with cystoid macular edema after cataract surgery. Methods: The present retrospective study was comprised of patients diagnosed with cystoid macular edema after cataract surgery performed between March 2006 and March 2008. To treat the edema, intravitreal triamcinolone injection was administered. Best corrected visual acuity (BCVA) and central macular thickness were measured, and complications as well as efficacy of the treatment were evaluated. Results: Twelve eyes were selected for the present study with a mean patient age of 67.3 years. The average period between cataract surgery and diagnosis of cystoid macular edema was 7.6 weeks. All 12 eyes received an intravitreal triamcinolone injection, and the patients were followed up for an average of 6.7 months. BCVA (log MAR) was changed from 0.29 ± 0.12 to 0.11 ± 0.09, showing statistically significant improvement (p = 0.000). The OCT showed that the average CMT was statistically decreased from 390.58 ± 94.98 μm to 165.17 ± 39.95 μm (p = 0.001). No complications were reported after the procedure, and vision and edema improved after one month in all 12 eyes. Conclusions: After performing intravitreal triamcinolone injection as a primary treatment method for cystoid macular edema which developed after cataract surgery, rapid recovery and improvement of vision and macular thickness were confirmed in all 12 eyes. J Korean Ophthalmol Soc 2012;53(3):428-433

^99mTc-DMSA 검사에서 상대 신섭취율 산출 시 양면상 촬영의 유용성에 대한 고찰

김주연,이한울,권오준,김정열,박민수,조석원,강천구,김재삼,Kim, Joo-Yeon,Lee, Han-Wool,Kwon, O-Jun,Kim, Jung-Yul,Park, Min-Soo,Cho, Seok-Won,Kang, Chun-Goo,Kim, Jae-Sam 대한핵의학기술학회 2015 핵의학 기술 Vol.19 No.1

$^{99m}Tc-DMSA$ 신장 신티그라피는 피질에 주로 섭취되어 신실질을 영상화하고 좌우 신장 및 배후방사능에 관심영역을 설정함으로써 상대 신섭취율을 평가할 수 있는 검사로, 진단 및 치료 후 경과관찰에 이용되고 있다. 본 논문에서는 후면상과 양면상 촬영 시 그리고 신장의 깊이를 적용한 경우의 상대 신섭취율 변화를 비교하여 상관관계를 알아보고자 한다. 실험은 신장 팬텀 및 조직등가물질을 이용하여 신장의 깊이에 차이를 주며 깊이 당 각 5번씩 총 25번을 진행하였다. 임상연구는 2014년 2월부터 10월까지 본원에 내원하여 $^{99m}Tc-DMSA$ 검사를 시행한 36명의 성인 환자를 대상으로 하였다. 장비는 감마카메라 INFINIA를 사용하였으며 GE사의 Xeleris Ver. 2.1220을 이용하여 신장 및 배후 방사능 모두 자동으로 관심영역을 설정하였다. 또한 환자별 신장 깊이의 차이를 고려하여 측면상을 촬영한 후 실제 신장 깊이를 측정하였다. 후면상에서의 산술평균값과 양면상에서의 기하학적 평균값 그리고 후면상에 신장 깊이를 적용해준 상대 신섭취율을 비교해보고 유의한 차이가 있는지 살펴보았다. 팬텀 실험 결과 좌, 우 신장 깊이의 차이가 1 cm 미만인 경우에는 양면상을 촬영했을 때와 후면상에 실제 깊이를 적용해준 경우 유의한 차이를 보이지 않았으나(P>0.05), 1 cm를 초과한 경우에는 유의한 차이를 보였다(P<0.05). 임상 연구에서는 후면상만을 촬영해준 경우와 후면상에 신장 깊이를 적용해준 경우의 상관관계(r=0.988)에 비해 양면상을 촬영해준 경우와 후면상에 신장의 깊이를 적용하여 보정해준 경우가 더 높은 상관관계(r=0.999)를 나타냈다. 본 연구에서는 양면상과 후면상을 촬영했을 때의 상대 신섭취율 차이를 확인할 수 있었다. 후면상만 촬영한 경우에도 깊이를 보정해줬을 때와 비교하여 상관관계가 있음을 알 수 있었으나 오차를 줄이기 위해서는 양면상을 촬영해주는 방법을 권고한다. Purpose $^{99m}Tc-DMSA$ renal scintigraphy serves as location, size and shape of kidney, so it has been used for diagnosis and passage observation after the operation or treatment. There are 3 methods of calculating the relative renal uptake ratio such as geometric mean of the counts from the anterior and posterior views, arithmetical mean from the only posterior view and posterior view which applied the renal depths. In this study, we seek to correlation between the change of total relative uptake ratio according to different inspection methods of obtaining the renal count rate. Materials and Methods The phantom experiments proceeded 5 times depending on each renal depth with the kidney phantom and tissue equivalent materials. In the clinical research, we investigated 36 adult patients who had visited our hospital from february to october, 2014 and received $^{99m}Tc-DMSA$ renal scan. The equipment was used as a gamma camera named INFINIA (General Electric Healthcare, milwaukee, USA) and we drew the region of interests through semiautomatic method by using Xeleris Ver. 2.1220 of GE. In addition, we obtained the lateral view of kidney to measure the renal depth of each patient. Then the results were compared with 3 methods of calculating relative renal uptake ratio. Results The phantom studies show when the difference between the left ant right kidney depth were less than 1 cm, there were no statistically significant difference among values calculated through anterior and posterior views and only posterior view (P>0.05), while the excess of 1cm, the results showed a statistically significant change in the value (P<0.05). In case of clinical research, the correlation between total relative uptake ratio by obtaining both sides of image and posterior view applied the kidney depth (r=0.999) was higher than by obtaining only posterior view and applying the kidney depth to one side image (r=0.988). Conclusion This study has found that, the difference of calculating total relative uptake ratio compared with obtaining anterior and posterior views and only posterior view. In order to reduce the error, we recommend the method of obtaining anterior and posterior views and is considered to be useful, particularly the patients have similar uptake ratio of left and right kidney and difficulties of measurements of kidney depth.

테라비트급 나노 스케일 SONOS 플래시 메모리 제작 및 소자 특성 평가

김주연,김문경,김병철,김정우,서광열,Kim, Joo-Yeon,Kim, Moon-Kyung,Kim, Byung-Cheul,Kim, Jung-Woo,Seo, Kwang-Yell 한국전기전자재료학회 2007 전기전자재료학회논문지 Vol.20 No.12

To implement tera bit level non-volatile memories of low power and fast operation, proving statistical reproductivity and satisfying reliabilities at the nano-scale are a key challenge. We fabricate the charge trapping nano scaled SONOS unit memories and 64 bit flash arrays and evaluate reliability and performance of them. In case of the dielectric stack thickness of 4.5 /9.3 /6.5 nm with the channel width and length of 34 nm and 31nm respectively, the device has about 3.5 V threshold voltage shift with write voltage of $10\;{\mu}s$, 15 V and erase voltage of 10 ms, -15 V. And retention and endurance characteristics are above 10 years and $10^5$ cycle, respectively. The device with LDD(Lightly Doped Drain) process shows reduction of short channel effect and GIDL(Gate Induced Drain Leakage) current. Moreover we investigate three different types of flash memory arrays.

포도막염에 의한 이차개방각녹내장에서 마이토마이신 섬유주절제술과 아메드밸브삽입술의 임상성적

김주연,심형섭,김황기,손용호.Joo Yeon Kim. MD. Hyoung Sub Shim. MD. Hwang Ki Kim. MD. Yong Ho Sohn. MD. PhD 대한안과학회 2010 대한안과학회지 Vol.51 No.4

Purpose: To assess and compare the clinical outcomes of primary trabeculectomy with mitomycin C and Ahmed valve implantation for secondary open-angle glaucoma following uveitis. Methods: This study was conducted retrospectively on 30 eyes of 25 patients with open-angle glaucoma secondary to uveitis that had undergone trabeculectomy with mitomycin C and 33 eyes of 24 patients that had undergone Ahmed valve implantation. The clinical outcome indicators used in this study were intraocular pressure (IOP), number of anti-glaucoma agents, surgical success rate and occurrence of complications. Results: Mean IOP and surgical success rate in patients who had undergone trabeculectomy with mitomycin C after a 12 month postoperative period were 14.0±8.2 mmHg and 76.7%, respectively, while those of patients with Ahmed valve implantation were 13.2±7.7 mmHg and 81.8%. The data did not show clinical significance. There was greater risk of surgical failure in patients at a younger age and/or with diabetes mellitus in cases of having gone through trabeculectomy with mitomycin C. Conclusions: Both trabeculectomy with mitomycon C and Ahmed valve implantation can be considered as primary surgical treatments for patients with open-angle glaucoma secondary to uveitis. However, trabeculectomy with mitomycin C should only be applied to a limited extent in patients that are young and/or have diabetes mellitus. J Korean Ophthalmol Soc 2010;51(4):575-580

Ectopic cervical thymic squamous cell carcinoma misdiagnosed as thyroid cancer: a case report

김주연,정은정,Kim Jae-Myung,Lee Han Shin,박태진,정상호,Jeong Chi-Young,주영태 대한종양외과학회 2022 Korean Journal of Clinical Oncology Vol.18 No.2

Ectopic thymic neoplasm, particularly ectopic thymic carcinoma, is a rare disease that presents as a neck mass. Here, we present a case of ectopic thymic squamous carcinoma in a 65-year-old man who presented with persistent hoarseness. After fine needle aspiration cytology, the patient underwent total thyroidectomy with lymph node dissection. The final histopathological examination revealed the ectopic thymic squamous carcinoma. The patient was discharged without any postoperative complications. The patient received adjuvant radiation therapy and did not progress during the 1-year follow-up period.

2018 대한부정맥학회 심실빈맥 전극도자 절제술 가이드라인 Part 2

김주연,김성환,Yoo Ri Kim,김윤년,김준,김태훈,남기병,노승영,박경민,박형섭,박희남,배은정,오세일,윤남식,이만영,조영진,진은선,조용근,차태준,최종일 대한부정맥학회 2018 International Journal of Arrhythmia Vol.19 No.2

The recommendations outlined constitute the first clinical practice guidelines of the Korean Heart Rhythm Society regarding catheter ablation of ventricular arrhythmias (VA). This is a guideline PART 2, which includes VA in the structurally normal heart, inherited primary arrhythmia syndromes, VA related to congenital heart disease, as well as VA and sudden cardiac death observed in specific populations. In the structurally normal heart, treatment is guided by the occurrence of symptoms or the frequency of arrhythmias that cause ventricular dysfunction over time. Catheter ablation can be recommended in patients in whom anti-arrhythmic medications are ineffective. The sites of origin of arrhythmic activity are known to be the outflow tract, fascicles, papillary muscle, or the annulus. Specific cardiac channelopathies include congenital long QT and Brugada syndrome. This guideline discusses the diagnostic criteria, risk stratification, and treatment of these syndromes. We have included recommendations for adult congenital heart disease. Moreover, we have discussed the management of VA occurring in specific populations such as in patients with psychiatric and neurological disorders, pregnant patients, those with obstructive sleep apnea or drug-related pro-arrhythmias, athletes, and elderly patients.

갑상선 결절에 대한 세침흡인 세포검사에서 비진단적 검체의 특징과 치료 전략

김주연,정은정,정상호,주영태,정치영,이영준,홍순찬,최상경,하우송,박순태,Ju-Yeon Kim,Eun-Jung Jung,Sang-Ho Jeong,Young-Tae Ju,Chi-Young Jeong,Young-Joon Lee,Soon-Chan Hong,Sang-Kyeong Choi,Woo-Song Ha,and Soon-Tae Park 대한갑상선-내분비외과학회 2010 The Koreran journal of Endocrine Surgery Vol.10 No.4

한파에 따른 표층수온의 지연시간 고찰 - 서해, 남해 -

김주연,박명희,이준수,안지숙,한인성,권미옥,송지영,Kim, Ju-Yeon,Park, Myung-Hee,Lee, Joon-Soo,Ahn, Ji-Suk,Han, In-Seong,Kwon, Mi-Ok,Song, Ji-Yeong 해양환경안전학회 2021 海洋環境安全學會誌 Vol.27 No.6

본 연구에서는 강한 한파가 발생했던 2018년과 온난 한파가 발생했던 2019년의 기온에 따른 수온의 반응 및 지연시간과 북풍계열 바람 빈도와의 상관관계를 분석하였다. 사용된 시간 자료는 국립수산과학원에서 제공하는 7개 지점 해역별 수온자료와 수온관측소 인근 7개 지점 AWS 기온자료를 이용하였다. 관측되지 못한 자료는 내삽법으로 근사값을 계산하였고, FIR Filter를 이용하여 자료의 주기성을 파악하였다. 그 결과, 강한 한파가 발생했던 2018년은 북풍계열 바람을 통해 차가운 공기가 남하하면서 기온을 하강시켜 전 해역에 저수온을 유발한 반면 온난 한파가 발생했던 2019년은 평년 수준의 기온으로 하강하였지만 수온은 크게 변화하지 않았다. 강한 한파가 발생했던 2018년 기온 하강에 따른 수온의 지연시간은 평균 14시간으로 0.7 이상의 높은 상관성을 나타냈고 온난 한파가 발생했던 2019년은 평균 지연시간이 20시간으로 0.44-0.67 사이의 상관성을 보였다. 본 연구를 통해 해역별로 기온 하강에 따른 표층수온의 반응을 해석하였고 지연시간을 파악함으로써 양식생물의 피해를 최소화하고 한파 피해의 신속한 대응에 기여할 수 것으로 기대한다. In this study, we examined the sea surface temperature (SST), air temperature (AT), and their time lag in response to an extreme cold wave in 2018 and a weak cold wave in 2019, cross-correlating these to the northern wind direction frequency. The data used in this study include SST observations of seven ocean buoys Real-time Information System for Aquaculture Environment provided by the National Institute of Fisheries Science and automatic weather station AT near them recorded every hour; null data was interpolated. A finite impulse response filter was used to identify the appropriate data period. In the extreme cold wave in 2018, the seven locations indicated low SST caused by moving cold air through the northern wind direction. A warm cold wave in 2019, the locations showed that the AT data was similar to the normal AT data, but the SST data did not change notably. During the extreme cold wave of 2018, data showed a high correlation coefficient of about 0.7 and a time lag of about 14 hours between AT and SST; during the weak cold wave of 2019, the correlation coefficient was 0.44-0.67 and time lag about 20 hours between AT and SST. This research will contribute to rapid response to such climate phenomena while minimizing aquaculture damage.

출판저널 칼럼

김주연,Kim, Ju-Yeon 대한출판문화협회 1991 출판저널 Vol.85 No.-

독일문학의 맛에 매료된 세월

김주연,Kim, Ju-Yeon 대한출판문화협회 1997 출판저널 Vol.216 No.-

바라건데 언젠가는 18세기부터 오늘에 이르는 독일비평사 한권쯤 내 손으로 썼으면 한다. 이들을 읽을 때마다 그들의 예감과 통찰력에 나 자신 부끄러움을 느끼면서 언젠가 이들 수준에 이를 것인지 아득한 동경에 빠진다.