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김종금(JK Kim),임영진(YJ Lim),이광재(KJ Lee) 대한산부인과학회 1979 Obstetrics & Gynecology Science Vol.22 No.1
저서 등은 Omphalocele 1예를 경험하였기에 문헌적 고찰과 함께 보고하는 바이다. A case of Omphalocele experienced in this hospital recently is presented here, with brief review of the literature.
이양희(YH Lee),김종금(JK Kim),김상갑(SK Kim),황상의(SU Hwang) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.6
36세 경산부의 난관에 발생한 기형종 1예를 치험하였기에 간략한 문헌고찰과 아울러 증례를 보고하였다. A benign cystic teratoma of the left uterine tube which found incidentally at the age of 36-year-old house-wife is presented with a brief review of related literature.
Immunostimulatory Activity of Apios Tuber Extract on RAW264.7 Macrophage Cells
최준,김요섭,이은별,김종금,강태훈,장호희 대한미생물학회 2016 Journal of Bacteriology and Virology Vol.46 No.4
Apios americana Medik tubers are medicinal foods with anti-cancer and anti-inflammatory activities. However, mechanisms of immunostimulatory action of the Apios tuber extract (ATE) on macrophages have not been elucidated. In the present study, we investigated whether ATE could modulate immune responses, such as production of nitric oxide (NO), proinflammatory cytokines, and transcription factors, in RAW264.7 macrophage cells. ATE significantly increased the production of NO and proinflammatory cytokines such as interleukin-1β (IL-1β), IL-6, and tumor necrosis factor-α (TNF-α), and induced the mRNA and protein levels of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and proinflammatory cytokines in a dose-dependent manner. Furthermore, Western blot analysis revealed that ATE activated the transcription factor Nuclear Factor-κB and mitogen-activated protein kinases signaling cascades, including extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 kinase. In addition, we found that ATE induced the activation of macrophages through upregulation of toll-like receptor 4 (TLR4) and TLR2. Taken together, these findings indicate that ATE possesses a potential as a functional food with immunostimulatory activity.
박경일(K`I Park),임영진(YJ Lim),김종금(JK Kim) 대한산부인과학회 1979 Obstetrics & Gynecology Science Vol.22 No.4
저자들은 36세와 54세의 경산부에 발생한 과립막 포난종 2례를 경험하였기에 간단한 문헌고찰과 아울러 보고하는 바이다. Granulosa cell tumor is a very rare tumor of the ovary. Authors presented two cases of granulosa cell tumors of the ovary, and references were briefly reviewed.