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      • SCOPUSKCI등재

        황함유리간드의 금속착물 Ⅰ. 디티오카바메이트류의 니켈(Ⅱ)착물의 합성과 그 성질

        김인식,김찬우,김창수,In-Sik Kim,Kim Chan-Woo,Chang-Su Kim 대한화학회 1993 대한화학회지 Vol.37 No.2

        즈비터이온인 디티오카바메이트류의 암모늄과 이를 리간드로 한 니켈(Ⅱ)착물을 합성하였다. 이들 니켈(Ⅱ)착물의 적외선 및 전자흡수 스펙트럼과 전도도, 질량분석 등으로 그 특성을 조사하였다. 이들 니켈(Ⅱ)의 디티오카바마토류 착물은 물, 메탄올 및 아세톤과 같은 극성용매에 녹는다. 이들 니켈(Ⅱ)착물의 원소분석과 물리적 측정 결과에서부터 그 가능한 구조를 제시하였다. Syntheses and properties of zwitterionic dithiocarbamates and their nickel(Ⅱ) complexes are described. The complexes have been characterized by mass infrared and electronic absorption spectroscopy, and conductivity measurement. Ni(Ⅱ)-dithiocarbamato complexes are soluble in polar solvents such as water, methanol, and acetone etc. The possible structures were proposed on the basis of elemental analyses and physical properties.

      • KCI등재

        번식기와 비번식기의 한국산 꿩 고환간질조직의 형태계측학적 연구

        김인식,Kim, In-Shik 대한수의학회 2002 大韓獸醫學會誌 Vol.42 No.3

        The purpose of this morphometric study was to obtain detailed quantitative information on all cell types in the testis interstitium of Korean ring-necked pheasants combined with data on changes in the steroidogenic function of the testis during the breeding and nonbreeding seasons. Animals collected during the breeding season, testis weights, sperm production, serum testosterone levels, leuteinizing hormone-stimulated testosterone secretion, and the length of the seminiferous tubules were significantly (p < 0.05) increased as compared to the nonbreeding season. Seminiferous tubules occupied 93.25% of testis volume in the breeding season. Leydig cells constituted 0.82% of the testicular volume. The mean volume of an Leydig cell was $1039{\mu}m^3$, and each testis contained about 24.53 million Leydig cells. Testes of the pheasants during the nonbreeding season displayed a 98% reduction in testis volume that was associated with a decrease in the absolute volume of seminiferous tubules (98% reduction), tubular lumen(100%), interstitium(90%), blood vessels(84%), lymphatic spaces(97%), Leydig cells(79%), mesenchymal cells(51%), and myoid cells(61%). The number of Leydig cells, mesenchymal cells, myoid cells per testis in the breeding season was higher (p < 0.05) than in the nonbreeding season. Although the average volume of a Leydig cell was 74% lower in the nonbreeding season, the average volume of a myoid and mesenchymal cell remained unchanged. These results demonstrate that there are a striking differences in the testicular structure of the Korean ring-necked pheasant in the breeding and nonbreeding seasons. Every structural parameter of the Leydig cell was pasitively correlated with both serum and LH-stimulated secretion concentrations of testosterone. Correlation of changes in hormonal status with morphometric alterations of all Leydig cell suggests that the Korean-ring necked pheasant may be used as a model to study structure-function relations in the avian testis.

      • KCI등재

        흰쥐에서 고환 간질세포에 미치는 노화의 영향

        김인식,태현진,이여광,박영재,강형섭,박상열,박수현,박영석,이영훈,안동춘,최은영,양홍현,Kim, In-Shik,Tae, Hun-Jin,Li, Li-Guang,Park, Young-Jae,Kang, Hyung-Sub,Park, Sang-Youel,Park, Soo-Hyun,Park, Young-Seok,Lee, Young-Hoon,Ahn, Dong-Choon 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.4

        The present study investigated the effects of aging on Leydig cells of Sprague Dawley rats. Rats of 3, 6, 12 and 18 months of age were used. Testes of rat were fixed by whole body perfusion using a fixative containing 2.5% glutaraldehyde in cacodylate buffer, processed and embedded in epon-araldite. Using $1{\mu}m$ sections stained with methylene blue, qualitative and quantitative morphological studies were performed. Testis incubations were used to determine luteinizing hormone (LH; 100 ng/ml) stimulated testosterone secretory capacity per testis in vitro. Testosterone levels in the incubation medium, and testosterone and luteinizing hormone levels in serum of these four groups of rats were determined by radioimmunoassay. Morphological studies revealed that Leydig cells were more abundant in the testis interstitium at 6, 12 and 18 months when compared with 3 months. The volumes of Leydig cells per testis was significantly higher, at 6, 12 and 18 months of age than those at 3 months. The number of Leydig cells per testis was doubled at 6, 12 and 18 months of age compared with 3 months. The average volume of a Leydig cell was not significantly different between 3 and 6 months of age, however, at 12 and 18 months a significantly lower value was observed. LH-stimulated testosterone production per testis in vitro was reduced by 45% at 6 months of age compared with 3 months; a further significant reduction was observed at 12 and 18 months. Serum testosterone and LH levels were not significantly different between 3 and 6 months of age but at 12 and 18 months a significantly lower value was observed in both groups for these hormones. These results showed that signs of aging are apparent in Leydig cells of Sprague Dawley rats at 12 months of age.

      • KCI등재

        구-구갭의 섬락 특성에 미치는 연소화염의 영향

        김인식,이상우,Kim, In-Sik,Lee, Sang-Woo 한국조명전기설비학회 2005 조명·전기설비학회논문지 Vol.19 No.1

        본 연구에서는 구-구갭을 수평 배치하였을 때, 연소화염에 의한 교류 및 직류 플래시오버전압 특성을 조사하였다. 화염에 의한 플래시오버 극성을 조사하기 위해 전압 및 전류파형을 측정하였으며, 플래시오버가 발생되기 전에 쿨롱력에 의한 화염의 형상 변화를 관찰하였다. 또한 플래시오버 전압의 저하 요인으로서 상대공기밀도의 저하 및 연소화염의 열전리 영향에 대해 고찰하였다. 실험 결과, 구-구갭에서 접지측 전극과 갭길이의 비를 k라고 할 때, 화염위치 k:0(접지측), k=0.5(중앙부) 및 k=1.0(전원측)인 경우 화염에 의한 교류 섬락전압의 평균값은 화염이 없을 때에 비해 각각 79.9, 82.9 및 $87.5[\%]$ 저하되었으며, 또한 화염의 높이 h=0, h=5 및 h=9[cm]일 때 교류 플래시오버 전압의 평균값은 화염이 없는 경우를 기준으로 하였을 때 각각 85.0, 40.8 및 $28.2[\%]$ 저하되었다. 소규모 연소화염에서의 열전리 영향은 크지 않는 것으로 나타났다. In this paper, reduction characteristics of the AC and DC flashover voltage in the horizontal air gap of sphere-sphere electrode system were investigated when the combustion flame was present near the high voltage electrode. The voltage and current waveforms were measured, when the flashover is occurred, in order to examine the flashover polarity by flame. The reduction characteristics of AC flashover voltage were discussed with the thermal ionization process, the relative air density and the deflection phenomena in the shape of flames that caused by the coulomb's force. As the results of an experimental investigation, It was found that the reduction of flashover voltages in sphere-sphere system, in comparison with the no flame case, are $79.9[\%]$ for k=0, $82.9[\%]$ for k=0.5, $87.5[\%]$ for k=1.0, $85.0[\%]$ for h=0[cm], $40.8[\%]$ for h=5[cm] and $28.2[\%]$ for h=9[cm] when ac voltage is applied. The influence for thermal ionization process of the combustion flame in small scale no particular change is recognized.

      • KCI등재후보

        한국인에서 안검하수의 원인별 분류

        김인식,최정범,라상훈,이상렬,In-Sik Kim,Jung-Bum Choi,Sang-Hoon Rah,Sang-Yeul Lee 대한안과학회 2005 대한안과학회지 Vol.46 No.8

        Purpose: To classify blepharoptosis in Korean patients, investigate the type of surgery used, and to compare the results with the data from Western countries. Methods: A total of 913 patients (1147 eyes) who underwent surgery for blepharoptosis from 1991 to 2003 were classified as either being congenital or acquired blepharoptosis, and then further subclassified into myogenic, aponeurotic, mechanical, or neurogenic ptosis according to Freuh’s mechanistic classification. The type of surgery for each type of blepharoptosis was investigated. Results: Of the 913 patients, 695 (76.1%) were congenital type, and 218 (23.9%) were acquired type. Freuh’s mechanistic classification by type was 84.7% myogenic type, 10.5% aponeurotic, 3.4% neurogenic, and 1.6% mechanical. By order of frequency, the type of surgery used was 60% frontalis suspension, 26.4% levator resection, 12.2% aponeurosis repair, and 1.4% conjunctivom?llerectomy. Conclusions: Congenital type was more common than acquired type. The proportion of congenital type was higher than the results reported from Western countries, but lower than those of previous Korean studies. This is probably due to the increased number of adults undergoing surgery for blepharoptosis compared to the past, and is a reflection of influence of socio-economic levels.

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