방사상각막신경염의 임상양상을 보인 세라티아 마르세센스 각막염 1예

김영준,김병선,유웅선,정인영,서성욱,유지명,김성재,Young Jun Kim,Byoung Seon Kim,Woong Sun Yoo,In Young Chung,Seong Wook Seo,Ji Myong Yoo,Seong Jae Kim 대한안과학회 2014 대한안과학회지 Vol.55 No.9

Purpose: To report a case of Serratia marcescens keratitis presenting as radial keratoneuritis. Case summary: A 15-year-old female who wore cosmetic and orthokeratology contact lenses but performed inadequate lens care visited our clinic with severe pain and visual disturbance in her left eye. On slit lamp examination, central corneal epithelial defect and stromal infiltration with radial keratoneuritis were observed. Based on clinical findings and past history, Acanthamoeba keratitis was highly suspected. The patient was treated with topical chlorhexidine 0.02% (Sigma-Aldrich Co., MO, USA) and moxifloxacin 0.5% (Vigamox<sup><font size=`2`>Ⓡ</font>, Alcon, TX, USA) per hour with 200 mg of oral itraconazol (Sporaone<sup><font size=`2`>Ⓡ</font>, LG, Seoul, Korea) once a day. Symptoms and corneal lesions did not improve after three days. After Serratia marsenscens was isolated from her contact lenses and solution, topical chlorhexidine 0.02% was discontinued, and intravenous ceftazidime (Tazime<sup><font size=`2`>Ⓡ</font>, Hanmi, Seoul, Korea) and fortified ceftazidime (50 mg/mL) eye drop was added. The corneal lesion dramatically improved, and after six months of follow-up, best-corrected visual acuity was 20/20 in the affected eye. Conclusions: Radial keratoneuritis can present not only in Acanthamoeba keratitis, but also in Serratia marsenscens keratitis. Confirmation of the isolated organism is useful when treating radial keratoneuritis. J Korean Ophthalmol Soc 2014;55(9):1380-1383

당뇨황반부종에서 안내 베바시주맙 치료 후 빛간섭단층촬영을 이용한 망막 혈관 직경의 변화

김영준,김형은,송원경,김성수,Young Jun Kim,MD,Hyoung Eun Kim,MD,Won Kyung Song,MD,Sung Soo Kim,MD,PhD 대한안과학회 2012 대한안과학회지 Vol.53 No.2

Purpose: To investigate retinal vascular caliber changes with Spectral Domain OCT after intravitreal bevacizumab injection in diabetic macular edema patients Methods: Thirty-four eyes of 29 diabetic macular edema patients who were intravitreously injected with bevacizumab (1.25 g/0.05 ml) were studied. Twenty-four fellow eyes of 24 patients with bevacizumab injection were also recruited as a control group. We measured retinal vascular caliber a distance of 0.5-1 disc sizes from the disc margin with Spectral Domain OCT at baseline and 1-month and 3-month follow-up visits. Central macular thicknesses were also measured. Results: Over the 3 months of study, there was a significant reduction of arteriolar caliber compared to baseline (p = 0.024), There was significant reduction of venular caliber at 1 month (p = 0.001) and 3 months (p = 0.000) compared to baseline. Venular caliber reduction at the 3-month follow-up was significantly correlated with central macular thickness (R = 0.487, p = 0.003). Conclusions: Retinal venular caliber reduction was significant at 1- and 3-month follow-up, and arteriolar caliber reduction was significant at 3-month follow-up compared to baseline. After 3 months of treatment, venular caliber reduction was correlated with reduction of central macular thickness. J Korean Ophthalmol Soc 2012;53(2):262-267

항공기내 연료 및 오일온도 변화에 대한 수치해석적 연구

김영준,김창녕,김철인,Kim, Yeong-Jun,Kim, Chang-Nyeong,Kim, Cheol-In 대한기계학회 2002 大韓機械學會論文集B Vol.26 No.8

A transient analysis on temperatures of fuel and oil in hydraulic and lubrication systems in an aircraft was studied using the finite difference method. Numerical calculation was performed by an explicit method with modified Dufort-Frankel scheme. Among various missions, air superiority mission was considered as a mission model with 20% hot day ambient condition in subsonic region. The ambience of the aircraft was assumed as turbulent flow. Convective heat transfer coefficient were used in calculating heat transfer between the aircraft surface and the ambience. For an aircraft on the ground, an empirical equation represented as a function of free-stream air velocity was used. And the heat transfer coefficient for flat plate turbulent flow suggested by Eckert was employed for in-flight phases. The governing equations used in this analysis are the mass and energy conservation equations on fuel and oils. Here, analysis of fuel and oil temperature in the engine was not carried out. As a result of this analysis, the ground operation phase has shown the highest temperature and the largest rate of temperature increase among overall mission phases. Also, it is shown that fuel flow rate through fuel/oil heat exchanger plays an important role in temperature change of fuel and oil. This analysis could be an important part of studies to ensure thermal stability of the aircraft and can be applicable to thermal design of the aircraft fuel system.

CO₂/N₂ 분리를 위한 SBS/UiO-66 기반의 고투과성 혼합 매질 분리막

김영준,문승재,김종학,Kim, Young Jun,Moon, Seung Jae,Kim, Jong Hak 한국막학회 2020 멤브레인 Vol.30 No.5

본 논문에서는 UiO-66 입자를 합성하고, 이를 열가소성 탄성중합체인 polystyrene-block-polybutadiene-block-polystyrene (SBS) 블록공중합체 매질에 삽입하는 방식으로 CO₂/N₂ 기체를 분리하기 위한 혼합 매질 분리막을 제조하였다. UiO-66가 고분자 매질에서 미치는 영향을 확인하기 위해 SBS와 UiO-66의 질량 비율을 변화시켜가며 혼합 매질 분리막을 제조하였다. 또한 UiO-66 입자의 균일한 분산을 위해서 두 차례에 걸친 초음파 처리 및 자성 막대를 이용한 물리적 혼합을 활용하였다. 제조된 시료들은 푸리에 변환 적외분광법(FT-IR), 주사전자현미경(SEM)을 통해 확인하였다. 또한 기체 투과 성능은 time-lag method를 통해 확인하였다. 이때, UiO-66의 함유량이 증가함에 따라 혼합 매질 분리막의 투과도는 크게 증가하였지만, CO₂/N₂ 선택도는 크게 감소하지 않았다. 가장 좋은 성능을 보인 20%의 UiO-66 입자를 함유한 분리막의 경우 663.8 barrer의 CO₂ 투과도와 13.3의 CO₂/N₂ 선택도를 보여주었다. 이러한 결과는 Robeson plot에서 순수 고분자 막에 비해 upper bound에 더 가까운 성능을 나타냈는데, 첨가된 UiO-66가 선택도를 크게 희생시키지 않고 기체 투과도는 두 배 이상 향상시켰기 때문이다. In this study, we developed mixed matrix membranes by blending thermoplastic elastomer, i.e. polystyreneblock-polybutadiene-block-polystyrene (SBS) block copolymer with the synthesized UiO-66 particles for CO₂/N₂ gas separation. To investigate the effect of UiO-66 particles in the SBS matrix, we prepared different mixed matrix membranes (MMMs) by varying the mass ratio of SBS and UiO-66 in the blend. To fabricate well-dispersed UiO-66, the SBS/UiO-66 mixture was sonicated and stirred thoroughly. The physico-chemical properties of prepared membranes were characterized by Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM). The gas separation performance was measured by time-lag method. The permeability of the MMMs increased significantly as the content of UiO-66 increased, but the CO₂/N₂ selectivity did not decrease significantly. The membranes containing 20% of UiO-66 particles showed the best performance with the CO₂ permeability and CO₂/N₂ selectivity of 663.8 barrer and 13.3, respectively. This result showed performance closer to upper bound than pure SBS membrane in the Robeson plot, as the added UiO-66 particles did not significantly sacrifice selectivity and more than doubled gas permeability.

도봉산-옥정 광역철도 건설공사 중 Recharge well 공법을 이용한 터널 및 개착정거장 주변 구조물 침하방지 대책

김영준,Kim, Yeong-Jun 한국터널지하공간학회 2019 자연, 터널 그리고 지하공간 Vol.21 No.2

장애인평생교육학(學) 융합 탐구: 모방 수준의 융합 학문체제 경계

김영준,도명애,Kim, Young-Jun,Do, Myung-Ae 국제문화기술진흥원 2020 The Journal of the Convergence on Culture Technolo Vol.6 No.4

이 연구는 장애인평생교육의 학문적 본질과 정체성을 융합의 관점에서 탐구하여 장애인평생교육학을 정립하고, 정립된 장애인평생교육학의 의미와 기능을 중심으로 모방 수준의 융합 학문체제를 경계하는데 목적을 두었다. 연구 방법은 문헌 분석을 기초로 전문가 회의를 병행한 절차가 구성되었다. 연구 내용은 장애인평생교육학이 장애 맞춤형 관점을 중심으로 특수교육학 등의 여러 인접 분야와 융합된 범주로 학문적 본질성과 정체성을 갖추어야 한다는 차원에서 장애인평생교육학의 보편성과 특수성을 일차적으로 탐구하였다. 그리고 장애인평생교육학의 보편성과 특수성을 통한 의미가 이론에 기반한 학문적 수준에서 뿐 아니라 실천에 근거한 기능적 수준으로 융합될 수 있는 구조체계를 탐구한 결과 역시 연구 내용으로 제시하였다. 연구 결과, 장애인평생교육학은 융합적 탐구 차원에서 보편성과 특수성을 구축할 수 있고, 위 여부의 충실도에 따라 종합적인 실천 수준의 지원체제를 마련할 수 있는 것으로 분석되었다. This study aims to establish the lifelong education for the disabled by exploring the academic nature and identity of lifelong education for the disabled from the perspective of convergence, and to guard against a convergence academic system at the level of imitation based on the meaning and function of the established lifelong education for the disabled. The research method consisted of a procedure in parallel with expert meetings based on literature analysis. The content of this study primarily explored the universality and specificity of lifelong education for persons with disabilities in the dimension that it should have an academic essence and identity as a category in which lifelong education for persons with disabilities is fused with several adjacent fields such as special education, centering on the perspective tailored to disability. In addition, the result of exploring the structure system in which the meaning through the universality and specificity of lifelong education for the disabled can be combined not only at the academic level based on theory but also at the functional level based on practice is also presented as the content of the study. As a result of the study, it was analyzed that lifelong education for the disabled can build universality and specificity in the dimension of convergent inquiry, and can establish a support system at a comprehensive level of practice according to the fidelity of the above.

하악전돌증환자에서 하악지시상분할골절단술 후 전산화단층촬영을 이용한 근심골편의 횡적인 변화에 관한 연구

김영준,국민석,박홍주,오희균,Kim, Young-Joon,Kook, Min-Suk,Park, Hong-Ju,Shet, Uttom Kumar,Oh, Hee-Kyun 대한악안면성형재건외과학회 2008 Maxillofacial Plastic Reconstructive Surgery Vol.30 No.3

Purpose: This study was performed to evaluate transverse changes of proximal segment after bilateral sagittal split ramus osteotomy (BSSRO) using 3-D CT in mandibular prognathism. Patients and methods: Twenty-two patients who underwent BSSRO for mandibular set-back in class III malocclusion without facial asymmetry were examined. Miniplates were used for the fixation after BSSRO. Facial CT was taken before and after BSSRO within 3 months. Frontal-ramal inclination (FRI), inter-gonial width (IGW) and intercondylar width (ICW) were measured in 3-D CT images using V-works $4.0^{TM}$ program. Student t-test was used to compare the changes between pre- and post-operative measurements using SPSS 10.0 program. Results: 1. Mean peroperative FRI value ($12.87{\pm}3.43^{\circ}$) was slightly increased to postoperative value ($14.13{\pm}3.72^{\circ}$) (p < 0.05). The average FRI increased 10.42% and the range was from $-2.46^{\circ}$ to $3.34^{\circ}$. 2. Mean peroperative IGW ($99.01{\pm}5.36$) was slightly decreased to postoperative IGW ($96.51{\pm}5.88mm$) (p < 0.05). The average IGW decreased 2.52 % and the range was from $-6.61^{\circ}$ to 0.91 mm. 3. Mean preoperative ICW ($125.01{\pm}5.30mm$) was slightly decreased to postoperative ICW ($125.40{\pm}5.45mm$) (p < 0.05). There is no significant difference between pre- and post-operative ICW. 4. There was significant correlationship between FRI difference and IGW difference (p < 0.05). Conclusions: These results indicate that the lower ramus of the proximal segment is moved inward after BSSRO procedure for mandibular set-back.

The Studies on the Organization and Expression of tRNA Gene IV. The Structure of the $tRNA^{Asp}$ Gene of Aspergillus nidulans

김영준,이승택,이병재,강현삼,Kim, Young-Joon,Lee, Seung-Taek,Lee, Byeong-Jae,Kang, Hyen-Sam 생화학분자생물학회 1986 한국생화학회지 Vol.19 No.2

A single clone harboring $tRNA^{Asp}$ gene was isolated by colony hybridization to the total tRN A gene clone of Aspergillus nidulans using the previously sequenced $tRNA^{Asp}$ probe. The gene was localized and sequenced by the method of Maxam and Gilbert. The sequence analysis revealed that the $tRNA^{Asp}$ gene has the anticodon of GUC, and contains an intervening sequence of 15 bases. The nucleotide sequence of this $tRNA^{Asp}$ gene was compared with $tRNA^{Asp}$'s of the other organisms. From this, some structural features in the flanking sequences and the gene were discussed. $tRNA^{Asp}$을 [r-$^{32}P$] ATP로 표지하여 Aspergillus nidulans 총 tRNA 유전자은행 (gene bank)과 colony hybridization 한 결과, pANt12가 양성반응을 나타내었다. pANt12 DNA를 추출하여 제한효소 지도를 작성하고 Southern hybridization하여 $tRNA^{Asp}$ 유전자를 포함하는 부분은 pASPI과 pASPII으로 두 번의 subcloning을 하고 유전자의 위치를 hybridization 방법으로 결정하였다. Maxam과 Gilbert의 방법으로 유전자의 염기순서을 결정하니 앞의 $tRNA^{Asp}$의 RNA 염기순서와 IVS 부분을 제외하고는 일치함을 보였다. $tRNA^{Asp}$ 유전자에는 다른 것과는 달리 15bp의 IVS 가 존재하는 것으로 나타났고 내부조절 부위에 대한 공통 염기순서, 가능한 ACT-TA box와 5'-측쇄부위의 TATTTT염기순서가 나타났다. tRNA 구조 유전자의 일부 염기순서와 같은 염기순서가 -15 부위에서 나타났으며 3'-측쇄부분에 short, discontinuous T-strech type이 존재하였다.

지역사회주민의 평생학습을 위한 도서관의 역할에 관한 연구

김영준,Kim, Young-Joon 한국문헌정보학회 2006 한국문헌정보학회지 Vol.40 No.1

21세기는 지식 정보화사회로 외부적인 환경 변화에 따라 국민들은 도서관에 다양한 기능을 요구하고 있다. 우선 전통적인 도서 보관(Container)기능에서 정보 접점(Connector) 기능을 요구하며. 정보 및 학습격차 해소를 위한 사회통합 기능과 지역단위의 인적자원개발을 위한 평생학습의 장으로서 역할을 기대하고 있다. 또한 정부 내의 환경도 교육인적자원부에 국가인적자원개발을 위한 '교육부총리제'를 도입하였으며 주5일제 및 고령화 사회에 대비한 도서관의 변화를 요구하고 있다. 지식 정보화, 주5일제, 고령화, 인적자원개발 등 평생학습사회의 새로운 패러다임과 불가분의 역학관계에 있는 도서관의 역할에 대하여 알아보고 앞으로 도서관이 추구해야 할 방향을 제시하였다. 21st century is a knowledge and information society. Keeping pace with this global environment change. people demand various roles from a library First, they demand to play a role of an 'Information Connector' rather than a traditional role of a 'Book Container'. Second, they demand to be the place of the social integration for a solution to the information and learning gap and the place for a life-long learning for HRD(Human Resources Development) by the community unit. In addition, not only introducing a system of 'Deputy Prime Minister and Minister of Education & HRD' for national HRD and 'Five-Day Week' but the advent of 'an Aging Society' demand a change of a library. This study researches roles of a library inseparably related to such new paradigms in the life-long learning society as the knowledge. information, five-day week. aging and HRD, and shows the right direction of a library to pursue in the future.

경제의 대외개방도 증가가 숙련 및 미숙련 부문의 고용에 미치는 영향

김영준,Kim, Young-Joon 한국개발연구원 2012 韓國 開發 硏究 Vol.34 No.1

본 논문은 경제의 개방화 진전이 고용구조에 어떠한 영향을 미치는지에 대한 주제를 다루고 있다. 이를 위해 본 논문은 경제주체의 이질성(heterogeneity)을 가미하여 Romer(1990)의 내생적 성장모형을 확장하였다. 이와 같은 이질성에 기반하여 본 모형은 한 경제의 고용구조(숙련 및 미숙련 부문의 상대적 고용의 크기)가 숙련노동의 수요 및 공급 조건에 따라 어떻게 결정되는지를 설명한다. 본 모형은 폐쇄경제에 기반하고 있으나 개방경제의 경우로 확장 가능하다. 개방경제의 경우로 확장된 모형에 따르면, 경제의 개방화 진전은 다음과 같은 두 가지 경로를 통해 고용구조에 영향을 미친다. 하나는 생산특화(specialization)를 통한 경로로서 개방 경제하에서 각국은 비교우위에 기반하여 부문별 생산량을 결정하는데, 이에 따라 부문별 노동수요가 결정되고 이는 고용구조에 영향을 미치게 된다. 다른 하나는 지식확산(knowledge spillover)을 통한 경로로서 경제의 개방화 진전은 지식확산을 촉진하는데, 이는 부문별 노동생산성에 영향을 미치고 따라서 고용구조에도 영향을 미치게 된다. 21개국의 국제패널자료를 이용하여 실증분석해 본 결과, 경제의 개방화 진전은 상기한 모형이 설명하는 바와 같이 위의 두 가지 경로를 통해 고용구조에 영향을 미침을 확인할 수 있었다. This paper consists of two parts. The first part introduces a simple endogenous growth model. It is based on Romer(1990), but extends the original model by incorporating individual workers skill heterogeneity. Based on the heterogeneity, the model has a labor allocation mechanism between skilled (research) and unskilled (production) sectors. Different from Romer(1990), the labor allocation is determined by both demand and supply conditions of the economy. The endogenous growth model presented in this paper shows how the shape of the distribution of human capital affects on the labor allocation, hence on the employment structure, wage profile and economic growth. The model can be extended to an open economy. With the heterogeneity, the extended model explains distributional effect as well as growth effect of the economic openness. The second part provides empirical evidence in support of the extension part of the model presented in the first part. Based on the endogenous growth framework as proposed by Romer(1990) and Rivera-Batiz and Romer(1991), the model explains how economic openness affects labor allocation between skilled and unskilled sectors. According to the model, economic openness can affect labor allocation through two channels; knowledge spillover and specialization. First, the openness promotes knowledge spillover and hence increases the productivity of workers in the skilled sectors. This makes the economy employs more workers in the skilled sector. On the other hand, the openness causes global specialization which leads more employment in the skilled sector for the developed countries but at the same time, leads less employment in the skilled sector for the developing countries since the developing countries have comparative advantages in the unskilled sector. The empirical results obtained using cross country panel data in this paper support these two effects of knowledge spillover and specialization.