화상 환자에서 신속 순차 시각 제시를 이용한 주의깜빡임에 관한 예비연구

김대희,전보라,서정훈,조용석,임해준,허준,김도헌,전욱,김종현,정명훈,최인근,이병철,Kim, Dae Hee,Jun, Bora,Seo, Cheong Hoon,Cho, Yongsuk,Yim, Haejun,Hur, Jun,Kim, Dohern,Chun, Wook,Kim, Jonghyun,Jung, Myung Hun,Choi, Ihngeun,Lee, Boung Ch 대한생물정신의학회 2010 생물정신의학 Vol.17 No.2

Objectives : Trauma patients have attentional bias which enforces traumatic memories and causes cognitive errors. Understanding of such selective attention may explain many aspects of the posttraumatic stress disorder(PTSD) symptoms. Methods : We used the rapid serial visual presentation(RSVP) method to verify attentional blink in burn patients with PTSD. International affective picture system(IAPS) was used as stimuli and distracters. In the 'neutral test', patients have been presented series of pictures with human face picture as target stimuli. Each picture had 100ms interval. However the distance between target facial pictures was randomized and recognition of second facial picture accuracy was measured. In the 'stress test', the first target was stress picture which arouses patient emotions instead of the facial picture. Neutral and Stress tests were done with seven PTSD patients and 20 controls. In '85ms test' the interval was reduced to 85ms. The accuracy of recognition of second target facial picture was rated in all three tests. Eighty-five ms study was done with eighteen PTSD patients. Results : Attentional blinks were observed in 100-400ms of RSVP. PTSD patients showed increased recognition rate in the 'stress test' compared with the 'neutral test'. When presentation interval was decreased to 85 ms, PTSD patient showed decrease of attentional blink effect when target facial picture interval was 170ms. Conclusion : We found attentional blink effect could be affected by stress stimulus in burn patients. And attentional blink may be affected by stimulus interval and the character of stimulus. There may be some other specific mechanism related with selective attention in attentional blink especially with facial picture processing.

Orthorhombic-NiSi/Si (010) 구조의 Pd 치환 연구: 제 1 원리 계산

김대희,김대현,서화일,김영철,Kim, Dae-Hee,Kim, Dae-Hyun,Seo, Hwa-Il,Kim, Yeong-Cheol 한국반도체디스플레이기술학회 2008 반도체디스플레이기술학회지 Vol.7 No.4

NiSi is less stable than the previously-used $CoSi_2$ at high temperature. Some noble metals, such as Pd and Pt, have been added to NiSi to improve its thermal stability. We employed a first principles calculation to understand the Pd segregation at the interface. An orthorhombic structure of NiSi was used to construct an orthorhombic-NiSi/Si (010). Lattice parameters along a- and c-axes in orthorhombic-NiSi were matched with those of Si for epitaxy contact. The optimized $1\times4\times1$ orthorhombic-NiSi (010) and $1\times2\times1$ Si (010) superstructures were put together to construct the orthorhombic-NiSi/Si (010), and the superstructure was relieved in calculation to minimize its total free energy. The optimized interface thickness of the superstructure was $1.59\AA$. Pd atom was substituted in Ni and Si sites located near interface. Both Ni and Si sites located at the interface were favorable for Pd substitution.

Y-doped BaZrO₃에서의 산소 공공과 프로톤의 이동

김대희,정용찬,박종성,김병국,김영철,Kim, Dae-Hee,Jeong, Yong-Chan,Park, Jong-Sung,Kim, Byung-Kook,Kim, Yeong-Cheol 한국세라믹학회 2009 한국세라믹학회지 Vol.46 No.6

We studied the transfer of oxygen vacancy and proton in Y-doped BaZr$O_3$ (BYZ) using density functional theory (DFT). An oxygen vacancy was generated in the $2{\times}2{\times}2$ BYZ superstructure by replacing two Zr atoms with two Y atoms to satisfy the charge neutrality condition. The O vacancy transfer between the first and second nearest O atom sites from a Y atom showed the lowest activation energy barrier of 0.42 eV, compared to the other transfers between first and first, and second and second in the superstructure. Two protons were inserted in the structure by adding a proton and hydroxyl that were supplied by the dissociation of a water molecule. The two protons bonded to the first and second nearest O atoms were energetically the most favorable. The activation energy barrier for a proton transfer in the structure was 0.51 eV, when either proton transferred to its neighbor O atom. This value was well matched with the experimentally determined one.

밀도범함수를 이용한 정방정계-NiSi (010)/Si 계면 층의 구조 연구

김대희,김대현,서화일,김영철,Kim, Dae-Hee,Kim, Dae-Hyun,Seo, Hwa-Il,Kim, Yeong-Cheol 한국전기전자재료학회 2009 전기전자재료학회논문지 Vol.22 No.5

Tetragonal-NiSi (010)/Si superstructures were calculated for studying the interface structure using density functional theory, The orthorhombic-NiSi was changed to the tetragonal-NiSi to be matched with the Si surface for epitaxy interface. The eight interface models were produced by the type of the Si surfaces, The tetragonal-NiSi (010)/Si (020)[00-1] superstructure was energetically the most favorable, and the interface thickness of this superstructure was the shortest among the tetragonal-NiSi (010)/Si superstructures. However, in the case of tetragonal-NiSi (010)/Si (010)[00-1] superstructure, it was energetically the most unfavorable, and the interface thickness was the longest. The energies and interface thicknesses of tetragonal-NiSi (010)/Si superstructures were influenced by the coordination number of Ni atoms and the bond length between atoms located at the interface.

재오개리(충청북도, 충주시)의 거미상

김주필(Joo Pil Kim),김대희(Dae Hee Kim) 한국거미연구소 2017 한국거미 Vol.33 No.2

2014년 5월 4일부터 2017년 8월 5일까지 충청북도 충주시 살미면 재오개리 일대를 한국거미연구회 회원 김대희가 주야로 채집한 결과, 총 18과 43속 47종이 조사 연구되어 이에 발표하는 바이다. 채집한 표본은 주필거미박물관에 보관되어있다. From May 4 2014 to August 5 2017, collected spiders of 18 families 43 Genera 47 species from Jaeogae-ri, Salml-myeon, Chungju-si, Chungcheongbuk-do. The result of investigation is reported by Dae-Hee Kim, the member of Arachnological Institute of Korea. The specimens of those spiders are placed in the Joo-Pil Spider Museum.

방추리(경기도, 이천시)의 거미상

김주필(Joo Pil Kim),김대희(Dae Hee Kim) 한국거미연구소 2017 한국거미 Vol.33 No.2

2013년 10월 20일부터 2017년 8월 6일까지 경기도 이천시 장호원읍 방추리 일대를 한국거미연구회 회원 김대희가 채집한 결과, 총 20과 44속 57종이 조사 연구되어 이에 발표하는 바이다. 채집한 표본은 주필거미박물관에 보관하였다. From October 20 2013 to August 6 2017, Kim Dae-hee, the member of The Arachnological Institute of Korea, collected the spiders in the whole area of Bangchu-ri, and reports 20 families, 44 genera 57 species of spiders. The collected spiders are placed in the Joo-Pil Spider museum in Namyangju-si, Gyeonggi-do.

거대 흉벽 결손에 대한 확장 외복사근 근피판을 이용한 흉벽재건 치험례

김대희,김정헌,송승용,Kim, Dae-Hee,Kim, Chung-Hun,Song, Seung-Yong 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.3

Purpose: The resection of locally advanced or recurred breast cancers frequently result in large chest wall defects and it leads to a great challenges to cover. Generally simple skin grafts are not a practical option for patients because of their poor cosmetic appearance and prognosis. The latissimus dorsi and rectus abdominis musculocutaneous flap have traditionally been recommended for closure of these large defects. Though the cosmetic result of reconstruction using these flaps is often excellent, but has significant drawbacks. Therefore, we thought that chest wall reconstruction using the external oblique musculocutaneous flap can be an alternative method for extensive chest wall defect related to large, locally advanced breast carcinoma. Methods & Results: We present a case of a 50-year-old Korean female, refered to our department with a left breast tumor for 10 months. CT demonstrate a large tumor on the left anterior chest wall and multiple nodules of varying size in the cervical areas and liver. FDG-PET showed areas of hot uptake throughout the left chest wall, mediastinum and liver. Biopsy was consistent with invasive ductal carcinoma (Grade III). The initial tumor was considered inoperable, so a series of chemotherapy was initiated. Though the size of the breast mass was slightly decreased, the patient continued to suffer from purulent discharge, unpleasant odor and contact bleeding of the mass, the salvage mastectomy was performed. Conclusion: We could reconstruct $23{\times}16\;cm$ sized large chest wall defect, resulting from the resection of a locally advanced breast carcinoma, using an external oblique musculocutaneous flap successfully. Immediate postoperatively checked flap was healthy. Overall result was good without any significant complications and discharged 3 weeks after operation.

어패류 및 종에 내재되어 있는 ${\beta}-Galactosidase$의 활성 비교

김대희,정창화,남윤권,민광식,김동수,Kim, Dae-Hee,Jeong, Chang-Hwa,Nam, Yoon-Kwon,Min, Kwang-Sik,Kim, Dong-Soo 한국양식학회 1996 韓國養殖學會誌 Vol.9 No.4

어류 및 폐류내에 내재하는 내재성 ${\beta}-galactosidase$의 활성도를 분석함으로서 외래유전자의 이식시 기초자료로 활용하고자 어류 6종 및 패류 4종을 대상으로 본 실험을 행하였다. 어류에 있어서의 X-gal 염색 결과 혈청 및 근육을 제외한 모든 조직에서 모두 positive ( + ) 염색 양상을 보였다. 패류에 있어서도 어류와 같은 양상을 보여 근육을 제외한 모든 조직에서 모두 positive 염색 양상을 보였으며 더욱이 참굴에 있어서는 폐각근 및 근육에 있어 매우 진한 염색 반응을 보였다. 근육으로 부터 DNA를 추출한 후 PCR을 수행한 결과 모든 종에서 positive (+) 결과를 나타내었으며, 어패류간 그리고 각 개체간 차이는 없었다. 각 장기별 ${\beta}-galactosidase$의 활성도 측정결과 모든 종에 있어서 혈청의 활성도는 무시할 만한 수준이었고, 근육에서 가장 낮게 나타났다. 미꾸라지와 잉어에서는 신장에서 가장 높은 활성을 보였고, 틸라피아는 소화관에서 가장 높은 값을 보였다. 해산어인 넙치의 경우 돌가지미, 문치가자미의 경우에 비해 간에서 활성이 높았다. 그러나 돌가자미 및 문치가자미인 경우 신장에서 가장 높은 값을 보였다. 패류에 있어서는 소화맹낭에서 가장 높은 활성값을 나타내었고 폐각근 및 외투막에서 매우 낮은 활성값을 나타내었다. 그러나, 참굴에 있어서는 참전복, 피조개 및 진주조개 보다는 상대적으로 폐각근 및 외투근에서 높은 활성을 나타내었다. Endogeneous activities of ${\beta}-galactosidase$-like enzyme in various tissues from several finfishes and shellfishes were examined by histochemical analysis based on X-gal staining and by fluorimetric measurement using 4-methylumbelliferyl-${\beta}$-D-galactoside (4-MUG). Species used in this study were 3 freshwater fishes, mud loach (Misgurnus mizolepis), common carp (Cyprinus carpio) and tilapia (Oreochromis niloticus) ; 3 marine fishes, olive flounder (Paralichthys olivaceus), stone flounder (Kareius bicoloratus) and marbled sole (Limanda yokohamae) ; and 4 shellfishes, abalone (Haliotis discus hannai), Pacific oyster (Crassoskra gigas), pearl oyster (Pinctada fucata martensii) and ark shell (Anadara broughtonii). The activities of ${\beta}-galactosidase$-like enzyme in all finfishes examined were significantly different among species, with the wide variations between tissues in a species. In general, the tissues such as kidney, intestine and liver were ones which showed the significantly higher values in 4-MUG fluorimetry and deeper staining patterns in X-gal analysis compared to other tissues. On the other hand, serum and muscle revealed the significantly lower activities than others did, regardless of species. Shellfishes were also found to have endogenous activities of ${\beta}-galactosidase$-like enzyme which were significantly varied depending on both species and organs in a species. Hepatopancreas from all shellfishes examined showed the deepest pattern in X-gal staining and also the highest value in 4-MUG analysis, while activities of ${\beta}-galactosidase$-like enzyme in adductor muscles and mantle muscles from all shellfish species in this study except Pacific oyster were negligible : Pacific oyster had the significant activity of this enzyme in muscle tissues. Putative endogenous lacZ fragment was amplified from both finfishes and shellfishes by polymerase chain reaction (PCR). The molecular size of PCR products was about 510 bp, and there was no difference in size among species examined.

북한강 참다슬기, Semisulcospira coreana (v. Martens) 의 번식생태

김대희,방인철,이완옥,백재민,Kim, Dae-Hee,Bang, In-Chul,Lee, Wan-Ok,Baek, Jae-Min 한국패류학회 2012 The Korean Journal of Malacology Vol.28 No.2

북한강에 서식하고 있는 참다슬기의 산란생태를 파악하기 위하여 생식소 발달단계에 따른 생식주기, 성비, 군성숙도, 보육낭유생의 월별변화 등 번식생태와 관련된 생물학적 기초 자료를 조사하였다. 각고에 대한 각경, 전중, 육중의 상관계수 ($R^2$) 는 0.7761-0.8719로 비교적 높은 상관관계를 나타내었다. 참다슬기의 암컷 생식소는 청록색, 수컷 생식소는 옅은 황색을 띠고, 암컷은 유생을 기르는 보육낭 (brood pouch) 을 가지고 있었다. 암수성비는 0.17-0.58의 범위로 계절적 불균형이 심하였으며, 여름철 암컷 비율이 높고 겨울철 암컷비율이 낮았다. 생식소의 조직학적 조사 및 비만지수, 생식소지수 조사 결과 봄, 가을에 두 번의 정점을 나타낸 후 급격히 떨어지는 경향을 보여 생식소 발달은 봄, 가을 연 2회 이루어짐을 알 수 있으며, 암컷 보육낭속의 유생수 월별변화도 연중 두 번의 피크를 나타냈었고, 보육낭속의 유생수는 월 평균 286-975범위로, 11월에 연중 가장 적었고 3월과 9월에 각각 975개, 863개로 연중 가장 많은 유생을 보유하였다. 50%가 성숙하는 군성숙체장은 각고 13.95 mm였으며, 각고 15mm 이상은 모든 개체가 성숙하고 보육낭을 형성하였다. To clarify reproductive ecology of the melania snail Semisulcospira coreana (v. Martens, 1886) in Bukhan River, gonad development, fatness, gonad index, sex ratio, first sexual maturity of population, monthly change of larvae number and developmental stages in brood pouches were investigated by six identification methods. As maturation progrsses, the sex of the snali can be distinguishable easily by color:: the ovary being blue-green and testis light yellow. The sex ratio of female to male individuals over 13.95 mm shell height was significantly different from 1:1 (${\chi}^2$ = 38.45, p < 0.05). The sex ratio of female to male individuals changed drastically according to the season, Based on the monthly variations of fatness, gonad index and histological analysis, spawning occurred twice a year (spring and autumn) and the mean size of matured eggs was $450{\mu}m$ in diameter. The monthly change of larval number in brood pouch showed also two distinct peaks in March and September during the year. The average number of larvae in brood pouches was 286 - 862 individuals. In this study, the number of larvae in the brood pouches were a minimum in December and a maximum in March (975 larvae). The biological minimum size (the size at 50% of group sexual maturity) of the melania snail was 13.95 mm in shell height in females and males. All females over 15 mm in shell height possesed brood pouches.

회원작품 - 마실

김대희,Kim, Daehee 대한건축사협회 2018 建築士 Vol.592 No.-