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김홍용(Hong Yong Kim),최혜민(Hai Min Choi),명기범(Ki Bum Myung),국홍일(Hong Il Kook) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.6
We present a case of multiple cutaneous leiomyoma in a 45 year old woman. About 20 years ago, multiple skin colored papules developed on right cheek and man4ibular area. About 10 years after the onset of the disease a uterine myoma developed which wae tree,ted by total hysterectomy. The skin lesions were gradually increasing in number and size, Some larger nodular lesions changed to brown in color and became painful after cold exposure. The histopathologic finding showed typical leiomyoma arieing from arrector pilorum muscle.
오지원,최혜민,국홍일 ( Chee Won Oh,Hai Min Choi,Hong Il Kook ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.3
We have performed the prick test on 70 patients with atopic lermatitis and at the same time measured the levels of serum IgE and peripheral eosinophil counts. The following results were obtained: 1. Patients with atopic dermatitis showed higher rates of positivty in the prick tests, espe cially to inhalant, allergens. 2. The levels of IgE were increased in these patients and those who were positive to at least one allergen in the prick tests showed higher levels of IgE ha those who were negative in the prick tests. 3. The patients with atopic dermatitis with a past history of allergic rhinitis demonstrated higher rates of skin test positivity. 4. There was no correlation between the levels of serum IgE and the peripheral eosinophil counts in these patients with atopic dermatitis, (Kor J Dermatol 1992; 30(1): 43-50)
이경신,명기범,국홍일 ( Kyung Sin Lee,Ki Bum Myung,Hong Il Kook ) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.2
We present two cases of angiosarcoma occuring on the scalp of aged person. The case 1 was a 74 year-old male who have had purplish colored, slightly raised irregular surfaced plsque on frontal scalp. The other case was a 69-year-old man who have had purplish nodule with satellite lesions on the right frontal area. The cases were confirmed by clinical picture, histologic findings. Treatment was not done because of refuse by patient.
자외선 조사 및 일광 차단제 도포후 자외선 조사시 신생쥐의 간조직내 Cytochrome 효소계와 Vitamin D 함량 변화에 관한 연구
류경옥(Kyung Ok Ryu),국홍일(Hong Il Kook),성낙응(Nak Eung Seong) 대한피부과학회 1986 대한피부과학회지 Vol.24 No.2
We observe changes of activation of hepatic microsomal cytochrome p-450, changes of formation of riug-and N-hydroxylation of 2-acetylaminofluorene, and changes of vitamin D, in the liver which exposed to UV light and expoeed to UV light after being applied by sunscreens. The results of our study are as shown below: 1. The contents of hepatic microsomal cytochrome p-45p of newborn rats were found to be remarkably increase in the group exposed to UV light for 3 weeks (p<0. 001), but such changes were much reduced in the group exposed to UV light for 3 weeks after being applied by sunscreens(p<0.05. p<0.001, ) 2.Cytochrome p-450 induced by UV light was found to be significantly increased ring and N-hydroxylation of 2-acetylarninofluorene known as carcinogenic source for the liver. In the group exposed to UV light for 3 weeks after being applied by sunscreens, both of ring-and N-hydroxylation of 2-acetylaminofluorene were significantly reduced(p<0. 0, p<0. 001). 3, The contents of vitarnin D, in the liver of newborn rats were found to be gradually increased when they were exposed to UV light for 1 week or 3 weeks (p<0. 001), and in the group exposed to UV light after being applied by sunscreens, such changes were reduced remarkably(pg0. (301).
유경(Kyung Yoo),한지윤(Jee Yoon Han),국홍일(Hong Il Kook) 대한피부과학회 1983 大韓皮膚科學會誌 Vol.21 No.4
A statistical evaluation was made on 248 patients who were consulted to the Department of Dermatology during the disabled patients admission in Korea Veterans Hospital from July 1, 1980 to June 30, 1982. The resuIts were as followings: l. Among the 248 disabled patients, the most common patients, who constituted 68. 8% of the total, were amputee of lower extremity (25.2%), patient of posttraumatic osteoarthritis (23. 2/) and paraplegia (20. 4%). 2. In age distribution, the most frequent age groups were 50 to 59 years, 42, 4 , and the lowest age groups were 60 to 69 years, 4. 0g. 3. The 6 most common dermatoses were Eczema (36. 8%), Fungal infection (33. 6%), Drug eruption (8. 0%), Acne vulgaris (6. 4%), Urticaria and Scabies (3. 2% each). 4. In seasonal distribution, the highest incidence (32. %) occurred on winter, and the lowest incidence (14. 0%) on Spring. Eczema was prevalent during Autumn and Winter season and Fungal infection during Summer season. -countinue-
조미형(Mi Hyung Cho),함정희(Jeong Hee Hahm),국홍일(Hong Il Kook) 대한피부과학회 1984 대한피부과학회지 Vol.22 No.5
A case of acute febrile neutrophilic dermatosis (Sweet's syndrome) characterized by tender erythematous plaques on the face, neck, and limbs was reported. This 43-year-old male patient has been suffering from fever and sore throat prior to development of skin lesions. Positive laboratory findings were polymorphonuclear leukocytosis and elevated erythrocyte sedimentation rate. The symptoms well responded to corticosteroid therapy.
접촉 피부염의 역학적 연구 ( 제 1 보 ) - 공동 연구 -
은희철(Hee Chul Eun),고창조(Chang Jo Koh),국홍일(Hong Il Kook),김덕현(Duck Hyun Kim),김정원(Chung Won Kim),김홍직(Hong Jig Kim),명기범(Ki Bum Myung),문기찬(Kee Chan Moon),이일수(Eil Soo Lee),임수덕(Soo Duk Lim),허충림(Choong Rim Haw) 대한피부과학회 1986 大韓皮膚科學會誌 Vol.24 No.3
The present work is the first joint epidermiological study of contact dermatitis carried out by the Korean Contact Dermatitis Research Group which was organized in 15i8p. For the past 2 years total 937 patients with contact dermatitie and suspected contact dermatitis have been routinely patch tested with Hollister-Stier standard battery (28 different antigens) by using Finn Chamber at 10 different General Hospitals which were located around Seoul area. The MOHL index was quite different from the western data, which was characterized with less male, rare leg ulcer and less occupational cases. However, housewife hand eczema cases were more common. The most common senaitiaers were ammoniated mercury, nickel sulfate, potassium dichromate, cinnamic alcohol, neomycin sulfate, paraphenylendiamine, balsam of Peru and thimerosal in order of frequency.
후천성 양측성 Ota 모반양 반의 임상 및 병리조직학적 관찰
조미형(Mi Hyung Cho),명기범(Ki Bum Myung),국홍일(Hong Il Kook) 대한피부과학회 1986 大韓皮膚科學會誌 Vol.24 No.5
We observed the clinical and histopathologic characteristics of acquired, bilateral nevus of Ota-like macules in each 80 and 23 patients. The results were as follows: 1. All patients were female and the peak age of onset was third decade with an a,verage age of 27.4 years. 2. The colors of lesions were slate, brown, dark brown, and blue black in order of freguency. 3. The lesions were most comrnonly observed in the malar area and alae nasi. 4. Three patients had family history of acquired, bilateral nevus of Ota-like :macules. 5. Histopathologically pigment-bearing cells, bipolar or irregular in shape, were found mostly in the upper- and mid-portion of the dermis. The melanocytes showed weakly positive dopa reaction. 6. In electron microscopic observation, these pigrnent-bearing cells contained many singly dispersed melanosomes in stage 3 and 4 of melanization and wece surrounded by an extracellular sheath.