건선의 임상적 관찰

함정희 (Jeong Hee Hahm) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.5

Psoriasis is a common chronic recurrent inflammatory disease of the skin characterized by round, circumscribed, erythematous dry scaling patches of various sizes, covered by grayish white or silvery white, imbricated and lamella scales. The number of psoriasis have tendency to increase on these days in Korea. To evaluate a general tendency of psoriasis at the Department of Dermatology, College of Medicine in Ewha Womans University in 1982, 281 cases of psoriasis at OPD were analized by the clinical data. The results were as follows: 1. Male incidence was 122(43. 4%) and female 159(56. 6%) out of 281 cases of psoriasis. There is no signiifcant sex differences(M: F 1: 1. 3). 2. The peak incidence of age group was aged between 20 to 29(33. 1%). The incidence under 20 was 15. 3%. Mosi: of the patients(68.0%) was aged between 20 and 49. R. The most frequent site of involvement was on the entire body(47. 7%). Frequent involved site in descending order were lower extremities, upper extremities, scalp, elbows and knees. 4. There was no significant seasonal variation in psoriasis in 1982(Spring: 26. 7%., Summer: 25. 6%, Fall: 18. 5% Winter: 29. 2g). 5. The incidence of psoriasis in 1982 at OPD of Ewha Womans University hospital was 1. 95% in total new patient of 14, 424.

청소년기와 성인기 여드름의 임상 양상 및 여드름에 관한 인식도의 비교 분석

함정희(Jeong Hee Hahm),강민정(Min Jung Kang) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.5

N/A Background:Acne has been recognized as a common disorder of adolescence but recent studies have documented increased prevalence of post-adolescent acne. Objective:The purpose of this study is to evaluate and compare the clinical features and subjective concepts about aggravating factors in adolescent and post-adolescent acne. Methods:367 patients who visited the department of Dermatology, Ewha Womans University Hospital from November, 1998 to February, 1999 were studied. 193 of the patients were below the age of 22(adolescent group) and 174 above the age 25(post-adolescent group). Results:1. In the predominant sites in the face, jaw and perioral area more common in post-adolescence than in adolescence. 2. Major acne types were papulopustular, comedonal and cystic with decreased order of frequency in both age groups, and cystic acne was more common than comedonal in male population in both groups. The severity of acne is worse in adolescence than in post-adolescence (p<0.05). 3. Facial acne scar was found in 85% of adolescence and 90% of post-adolescence. Ice-pick, macular atrophic, hypertrophic, keloidal and follicular elastolytic scars were involved in decreased order in both groups. The severity of acne scar in post-adolescence was not significantly higher than that of adolescence(p>0.05). There was significant positive correlation between severity of scar and duration of acne in both groups(r=0.19 and r=0.23, p<0.05). 4. Among the post-adolescent group, 30% presented with late-onset and the features of hyperandrogenism were more commoly associated in post-adolescent female patients(39%) than adolescent(33%). 5. Aggravating factors in the post-adolescence were more commonly noted in the use of cosmetics, occupation and certain food, while in the adolescence, physical fatigue, psychologic stress, excessive sweating and sun exposure were. 6. 34% of adolescence and 71% of post-adolescence had history of medical intervention. The rate of non-responsive and relapsed acne after one or more cycle of oral medication within one month was higher in post-adolescence(59%) than in adolescence(38%).Conclusion:Compared with adolescent patients, post-adolescent patients were characteristically more commonly associated with features of hyperandrogenism and resistance to one or more cycles of oral medication and aggravating factors of acne were more closely related to the occupations including chronic exposure to materials and use of cosmetics. Female post-adolescent patients who were presented with late onset acne, were resistant to treatments or with features of hyperandrogenism should be carefully studied for abnormalities of the ovarian, adrenal or local androgen metabolism. (Korean J Dermatol 2000;38(5):589~599)

피부과로 의뢰된 입원환자에 대한 임상분석의 비교연구

함정희 (Jeong Hee Hahm) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.5

424 patients who were consulted to department of dermatology during their admission in Ewha Womans University Hospital from Jan.to Dec. 1991 were analyzed in order to evaluate the tendency of dermatologic problems. The results were as follows: 1. The most frequent dermatologic problem was eczema. 2. Age prevalence was highest between 40-49. 3. The most frequent dermatologic problem was found in spring. 4. The pathents in internal rnedicine were most, frequently consuled. 5. Patients with diabetes mellitus were most frequently consulted among systernic disease. 6. There was no significant difference in sex ratio. 7. The rate of consultation for acne was increased compared to 1976. 8. The rate of cosultatin for fungal infection was increased compared to the frequency rate of fungal infection of new patients at OPD in 1991. (Kor J Dermatol 1992;30(5):651-658)

지단(指端) 흑자양(黑子樣) 흑색종(黑色腫) 1예(例)

함정희 ( Jeong Hee Hahm ),장주은 ( Joo Eun Jang ) 대한피부과학회 1983 大韓皮膚科學會誌 Vol.21 No.6

색소레이저 ( Pulsed Dye Laser , SPTL - 1 ) 로 치료한 피부혈관병변의 임상효과에 관한 연구 ( 제 1 보 )

김정원,함정희 ( Jeong Won Kim,Jeong Hee Hahm ) 대한피부과학회 1991 大韓皮膚科學會誌 Vol.29 No.6

N/A The pulsed dye laser(Candela SPTL-1) is a flashlamp excited dye laser, using the principles of selective photothermolysis that selectively targets the abnormal microvasculatures of cutaneous lesion while sparing adjacent structures including the epidermis, emitting at 585nm wavelength, pulse duration of 450 ?sec and 5㎜ spot size. During the period of 6 months from April to September 1989, at O.P.D., Department of Dermatology, Ewha Womans University Hospital, 106 patients with cutaneous vascular lesions were analyzed to evaluate the clinical effects by the pulsed dye laser. The results were as follows: 1. Patient distribution of the cutaneous vascular lesions included 66 patients with nevus flammeus, 29 with telangiectasia, 8 with strawberry heniangioma and 3 with cavernous hemangioma. 2. Clinical effects a. Nevus flammeus : 73.0% of adults and 50.0% of children showed excellent or good results. b. Telangiectasia : 89.6% of patients showed excellent or good results. c. Hemangioma : 50.0% of patients with strawberry hemangioma and 66.7% of patients with cavernous hemangioma showed good results. d. Complications included transient hyperpigmentation(24.5%), hypopigmentation(5.7%) and atrophic scar(5.7%). There was no posttreatment s?lerosis or hypertrophic scarring.

피부에 전이된 Ewing 육종

신정현(Jeong Hyun Shin),조소연(Soyun Cho),황규광(Kyu Kwang Whang),함정희(Jeong Hee Hahm) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.2

Ewing's sarcoma is a highly anaplastic, small round cell tumor, primarily arising in the intramedullary portion of the bone, and metastasis is common. Its origin is unknown. We describe a case of cutaneous metastatic Ewing's sarcoma in the pubic area in a 23-year-old female, who had been diagnosed as having Ewing's sarcoma of the pelvic bone three years ago, and treated by wide excision, chemotherapy and radiation therapy. Histopathologic examination of her nodular lesion revealed a tumor of small round cells whose membranes were positive for CD99. She was managed by conservative treatment but expired one month later. To our knowledge, Ewing's sarcoma metastatic to the skin has not been reported previously in the world. This case supports the neuroectodermal origin of this tumor and that cutaneous metastasis of this tumor is a hallmark of grave prognosis. (Korean J Dermatol 2000;38(2):249~253)

Flashlamp - pumped pulsed dye laser ( SPTL - 1 ) 로 치료한 화염상 모반의 조직학적 변화에 관한 연구

김정원,함정희 ( Jeong Won Kim,Jeong Hee Hahm ) 대한피부과학회 1992 大韓皮膚科學會誌 Vol.30 No.6

CO2 레이저를 이용한 양성 피부 종양의 치료 효과

박미연,함정희 ( Mi Youn Park,Jeong Hee Hahm ) 대한피부과학회 1993 大韓皮膚科學會誌 Vol.31 No.4

Bsckground : CO laser emiis energy in the mid portion of the infrared spectrum at a wavelengt,h of 10,600nm. The CO laser is the workhorse laser in the treatment of cuianeous disease. With water as the chromophore(light-absorbing compound), CO laser light is highy absorbed in biologic tissue. Human body tissue comprises between 75% to 90% of water. The CO laser is superficially absorbed by tissue water, with little scat ter, limiting penetration into the skin to less than 0.1 mm. The beam can be delivered with a large spot size and low power density(defocus mode) or focused tightly with great power density(focused mode). As a result : the CO laser may be used both to vaporize and to cut tissue while coagulating blood vessels, providing a relatively bloodless su gical field. Objective : The purpose of this study was to evaluate the therapeutie effect of the CO laser on benign cutaneous tumors. Methods : 114 cases of benign cutaneous tumors treated with the CO laser between October 1987 and September 1992 were subjected to detailed analysis, The CO later is Pizer Laser system(U.S.A., Ca) Model 20-C CO. The laser produces power output that ranges from 0 to 25 W of continuous wave. Spot size is variable, between 0.3mm and 2mm. Results : 1. Angiofibromas and seborcheic keratoses showed very good response(95.3%, 92.8% ). 2. Syringomas showed a good esponse(82.8%). 3. Epidermal nevus and trichovpitheliomas showed a fair response(58.5%, 60%). 4. There were hypertrophic scars(10.5%) and transient hypopigmentation. Conclusion : The Co laser was a very effective modality for the treatment of benign cutaneous tumors such as angiofibromas, seborrheic keratosis and syringomas. (Kor J Dermatol 1993; (31):502-507)

Acute Generalized Exanthematous Pustulosis

박혜진,강호정,함정희 ( Hae Jin Park,Ho Jung Kang,Jeong Hee Hahm ) 대한피부과학회 1997 대한피부과학회지 Vol.35 No.1

Acute generalized exanthematous pustulosis(AGEP) has symptoms of abrupt onset of a widespread pustular eruption on an erythematous. base. Most cases appear to be related to drug reactions, mainly antibiotics, but viral infections and hypersensitivity to mercury may cause AGEP. The essential features of AGEP include. (1) numerous(several dazen) small((5mm), mostly non follicular pustules arising on a widespread erythema:purpura and target-like lesions may be associated; (2) histology showing intraepidermal or subcorneal pustules associated with one or more of the following.clermal edema, vasculitis, perivascular eosinophils, or focal necrosis of keratinocytes; (3) fever (over 38C); (4) neutrophilia, and (5) acute evolution with spontaneous resulotion of pustules within 15 days. We report a case of AGEP which presented with widespread tiny pustules on the whole body except the face, palms and soles. There were petechia, purpura, and vesiculobullous lesions on the axilla, popliteal fossa and upper abdomen. A biopsy specimen from a pustule showed subcorneal pustules with perivascular polymorphous cellular infiltration, marked dermal edema and necrotic keratinocytes. There was complete resolution of the lesions within 10 days. (Kor J Dermatol 1997;35(l): 160-164)

Mohs 미세도식 수술 및 쌈지봉합 복원술을 이용한 융기성 피부섬유육종의 치험

최유원,황규광,함정희,이정복,Yoo Won Choi,Kyu Kwang Whang,Jeong Hee Hahm,Jung Bock Lee 대한피부과학회 1995 대한피부과학회지 Vol.33 No.6

Dermatofibrosarcoma protuberans is an uncommon, locally aggressive fibroblastic tumor, characterized by infrequent metastasis and a marked tendency of local recurrence after excision. Histologically, it shows large uniformed spindle shaped cells arranged in a cartwheel or storiform pattern. We report a case of dermatoribrosarcoma protuberans on the lower abdomen of a man aged of thirty, treated with Mohs micrographic surgery and purse-string suture repair. (Kor J Dermatol 1995;33(6): 1108-1113)