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한국인 원발성 간암환자 혈청의 α1-Fetoglobulin 에 관한 연구
남궁승 ( Seung Namkoong ),임수덕 ( Soo Duk Lim ),한필석 ( Shim Suk Hahn ) 대한내과학회 1971 대한내과학회지 Vol.14 No.6
Serum alpha-Fetoglobulin (AFP) was measured in 145 patients hospitalized at Seoul National University Hospital during period of July 1970 to March 1971. Experimental group consisted of 46 cases of primary hepatoma diagnosed by clinical and histological fin
건선환자의 말초혈액내 면역세포 ( T Cell , T Subsets 및 B Cell ) 의 정량과 광화학요법 ( PUVA ) 이 이들 면역세포에 미치는 영향에 관한 연구
허충림(Choong Rim Haw),정영철(Young Chul Jung),한을남(Eul Nam Han),임수덕(Soo Duk Lim),명기범(Ki Bum Myung),국홍일(Hong Il Kook) 대한피부과학회 1983 大韓皮膚科學會誌 Vol.21 No.5
Recent studies have demonstrated that the patients with psoriasis have various immune alternation in both humoral and cellular immunities. However the results of these are still controversial. These facts promoted us to analyze the immune cells (T cell, T subsets and B cell) by rosette method for these cells in peripheral blood of 15 patients with psoriasis. And we also analyzed the effects of photo- chemotherapy(PUVA) on these cells. The results were summerized as follows; 1. The mean values of T cell, T, T, cell and B cell in peripheral blood of the- patients with psoriasis before PUVA therapy were 56. 2+-5. 7%, 35. 1+-6.9%, 5. 5+l. 4%, 11. 6+4. 0% respectively, These results of immune cells showed signi- ficantly lower mean values when these were compaired with the mean values. of nomnal control group(T cell; 65. 2+-2. 9%, TM cell; 45. 8+-3. 2%, T cell; 7. 3+ 1. 3% B cell; 16. 2+2. 4%), respectively (T cell, Tm Tg, p <0. 01, B cell; p <0. 05). 2. The mean values of T cell, T, T, cell and B cell in peripheral blood -countinue-
대상포진환자의 말초혈액내 면역세포의 정량과 Natural Killer ( NK ) 세포 활성치에 관한 연구
우종설(Chong Seul Woo),정영철(Young Chul Jung),허충림(Choong Rim Haw),임수덕(Soo Duk Lim) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.4
By recent advance of immunologic techniques, it made possible to measure the immune cells and NK cell activity in peripheral blood of various immune altered eonditions. NK cell activity is related not only to malignancies but also to viral infectiona. The facts that the impairment of cell mediated immunity inducea the herpes zoster infection and frequent association with herpes zoster in the patienta with malignancy promote author to atudy the alteration of immune cells and NK cell activity in peripheral block. So author evaluated irnmune cells and NK cell activity of 18 patients with berpes zoster. The results are as follows; 1. The mean value of T cells, T cells showed significant differences between patients group(58.4-i-6.9%, 33.7-+11.7%) and normal healthy control group (68. 6+ 4. 7yo, 44. 2+-7. 0%) but T,' and B cells showecl no significant between patientagroup(6.9-+2.4%, 12.5+-5.7%) and.controlgroup(7.8-1.5%, 13.9-+2.3g%), statistically. 2. The mean value of NK cell activity in patients with herpes zoster group (62. 9+-ll. 2%) showed no significance cornpaired with the mean value of normal healthy control group(57. 9+-l4. 8%), statiatically.
정상인 및 나환자 표피 각질층의 수분 함량에 관한 연구
심우영(Woo Young Sim),김낙인(Nack In Kim),허충림(Choong Rim Haw),임수덕(Soo Duk Lim) 대한피부과학회 1985 대한피부과학회지 Vol.23 No.5
We evaluate the water content, hygroscopicity and water holding capacity in 40 healthy individuals and 17 leprosy patients by skin surface hydrometer(IBS Inc, Japan), and the correlation between the nerve destruction and the hydration state. In Eiealthy individuals the measuring sites were the flexor and extensor surfaces of the arm, forearm, thigh and leg, In leprosy patients we measured on the extensor surface of forearm with shows abnormal sensation, and opposite ar neighboring skin which shows normal sensation. The results are as follows: 1. The water content of healthy individuals is highest in the flexor surface af arm (49. 50 + 18.38ug ) and lowest in the extensor surface of leg(30.75 -12.09ug) 2. The hygrosccpicity of healthy individuals is highest in the flexor surface of arm(296. 30 + 70.75ug ) and lowest in the extensor surface of leg(24$. Q7+5) 5ppg) 3. The water content of the extensor surface of lorearm in leprosy patients, which .hows abnormal sensation, is decreased(16. 35 +20. 82 ug) and it is statisti calli significant when compared with healthy individuals(p<0.005). 4. The hygroscopicity of the extensor surface of forearm in leprosy patients. which shows abnormal sensation, is decreased(94. 29 + 71. 62 ug) and it is statistically significant when compared with opposite or neiphboring skin and healthy individuals(p<0. 005)
서웅석(Woong Suck Suh),이기호(Ki Ho Lee),허충림(Choong Rim Haw),윤재일(Jai Il Yoon),임수덕(Soo Duk Lim) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.1
Erythrasma is a chronic, superficial bacterial skin infection involving the body folds and toewebs, and sametimes it may be generalized. The causative organism of this disease is Corynebacterium minutissimum. But, in Korea, there are few reported case about this common condition. We experienced a case of erythrasma on 39-year-old male who have had well defined, brownish fine scaly patches on both crural areas for 15 years. We had treated this patient with topical antifungal agent for 1 month under impression of tinea cruris, But skin lesion was not improved. So, we reexamined the lesion and diagnosed it as genitocrural form of erythrasma with it's clinical appearance, red fluorescence under Wood's light. And we treated it with oral erythromycin.
정영철(Young Chul Jung),이기호(Ki Ho Lee),허충림(Choong Rim Haw),윤재일(Jai Il Yoon),임수덕(Soo Duk Lim) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.2
Acropustulosis of infancy is an uncommon, but not rare syndrome established as a new disease entity by Kahn and Rywlin(1976), which is characterized by recurrent, intensely pruritic vesicopustules on the distal extremities. We'd like to report a case of acropustulosis of infancy. Our patient was 19 month old girl who had been suffering from her skin disease since the age of 12 months. Intensely pruritic, 1 to 2 mm vesicopustules erupted on the palms, soles and the ventral aspects of the fingers. There were no bacteria, fungus and parasites(Sarcoptes scabiei) on the pustular lesions. Histopathologically, biopsy specimen of the left sole revealed large, well circumscribed intraepidermal pustule which was filled wth polymorphonuclear leukocytes. We confirmed our case as typical case of acropustulosis of infancy by it's characteristic clinical features and histopathologic findings. Severity of the skin lesions seems closely related to the dosage of dapsone. The eruptions were unresponsive to topical steroid, antibiotics and antihistaminics. But we observed that dapsone has dose dependent relationship with acropustulosis of infancy.
정영철(Young Chul Jung),심우영(Woo Young Sim),한을남(Eul Nam Han),김낙인(Nack In Kim),허충림(Choong Rim Haw),임수덕(Soo Duk Lim) 대한피부과학회 1983 대한피부과학회지 Vol.21 No.5
Juvenile xanthogranuloma is a benign disseminated xanthomatous and granulomatous condition of the skin and other organs. The skin lesions usually disappear spontaneously within 1 to 5 years. Our case was 4 month-old boy who had have match head to pea sized scattered yellowish papules and nodules on scrotum since age of 1 month and then these skin lesions gradually spread to trunk, face and scalp without subjective symptoms. Histopathologically, biopsy specimen of the trunk revealed massive accumulation of histiocytes at dermis. With fat stain, fat substance is demonstrated within the foamy histiocytes. The skull x-ray revealed coin sized, well circumscribed osteolytic lesion on the left parietal bone. By the age of two and half, most of the skin lesions and bone defect on skull x-ray disappeared spontaneously.