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Wu, R.B.,Munns, K.,Li, J.Q.,John, S.J.,Wierenga, K.,Sharma, R.,Mcallister, T.A. Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.11
Real time PCR was used in this study to determine the effect of triticale dried distillers grains with solubles (TDDGS) as a replacement for grain or barley silage in finishing diets on the presence of six classical ruminal bacterial species (Succinivibrio dextrinosolvens, Selenomonas ruminantium, Streptococcus bovis, Megasphaera elsdenii, Prevotella ruminicola and Fibrobacter succinogenes) within the rumen contents of feedlot cattle. This study was divided into a step-wise adaptation experiment (112 days) that examined the effects of adaptation to diets containing increasing levels of TDDGS up to 30% (n = 4), a short-term experiment comparing animals (n = 16) fed control, 20%, 25% or 30% TDDGS diets over 28 days, and a rapid transition experiment (56 days) where animals (n = 4) were rapidly switched from a diet containing 30% TDDGS to a barley-based diet with no TDDGS. It was found that feeding TDDGS as replacement for barley grain (control vs. 20% TDDGS) decreased 16S rRNA copy numbers of starch-fermenting S. ruminantium and S. bovis (p<0.001 and p = 0.04, respectively), but did not alter 16S rRNA copy numbers of the other rumen bacteria. Furthermore, feeding TDDGS as a replacement barley silage (20% vs. 25% and 30% TDDGS) increased 16S rRNA copy numbers of S. ruminantium, M. elsdenii and F. succinogenes (p<0.001; p = 0.03 and p<0.001, respectively), but decreased (p<0.001) the 16S rRNA copy number of P. ruminicola. Upon removal of 30% TDDGS and return to the control diet, 16S rRNA copy numbers of S. ruminantium, M. elsdenii and F. succinogenes decreased (p = 0.01; p = 0.03 and p = 0.01, respectively), but S. dextrinosolvens and S. bovis increased (p = 0.04 and p = 0.009, respectively). The results suggest that replacement of TDDGS for grain reduces 16S rRNA copy numbers of starch-fermenting bacteria, whereas substitution for barley silage increases 16S rRNA copy numbers of bacteria involved in fibre digestion and the metabolism of lactic acid. This outcome supports the contention that the fibre in TDDGS is highly fermentable.
Data Gap in Sacral Neuromodulation Documentation: Call to Improve Documentation Protocols
Christopher M. Hornung,Ranveer Vasdev,Kate A. Hanson,Rachael Gotlieb,Cynthia S. Fok,John Fischer,Nissrine A. Nakib,Dwight E. Nelson 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.3
Purpose: We quantified patient record documentation of sacral neuromodulation (SNM) threshold testing and programming parameters at our institution to identify opportunities to improve therapy outcomes and future SNM technologies. Methods: A retrospective review was conducted using 127 records from 40 SNM patients. Records were screened for SNM documentation including qualitative and quantitative data. The qualitative covered indirect references to threshold testing and the quantitative included efficacy descriptions and device programming used by the patient. Findings were categorized by visit type: percutaneous nerve evaluation (PNE), stage 1 (S1), permanent lead implantation, stage 2 (S2) permanent impulse generator implantation, device-related follow-up, or surgical removal. Results: Documentation of threshold testing was more complete during initial implant visits (PNE and S1), less complete for S2 visits, and infrequent for follow-up clinical visits. Surgical motor thresholds were most often referred to using only qualitative comments such as “good response” (88%, 100% for PNE, S1) and less commonly included quantitative values (68%, 84%), locations of response (84%, 83%) or specific contacts used for testing (0%). S2 motor thresholds were less well documented with qualitative, quantitative, and anatomical location outcomes at 70%, 48%, and 36% respectively. Surgical notes did not include specific stimulation parameters or contacts used for tests. Postoperative sensory tests were often only qualitative (80%, 67% for PNE, S1) with quantitative values documented much less frequently (39%, 9%) and typically lacked sensory locations or electrode-specific results. For follow-up visits, <10% included quantitative sensory test outcomes. Few records (<7%) included device program settings recommended for therapy delivery and none included therapy-use logs. Conclusions: While evidence suggests contact and parameter-specific programming can improve SNM therapy outcomes, there is a major gap in the documentation of this data. More detailed testing and documentation could improve therapeutic options for parameter titration and provide design inputs for future technologies.
Constantin Bu\c{s}e,Pietro Cerone,Sever Silvestru Dragomir,John Roumeliotis 대한수학회 2006 대한수학회지 Vol.43 No.5
A refinement of Gr"{u}ss type inequality for the Bochner integral ofvector-valued functions in real or complex Hilbert spaces is given. Relatedresults are obtained. Application for finite Fourier transforms ofvector-valued functions and some particular inequalities are provided.
Jonathan Hui,John Choy,Sid P. Suwandaratne,Jenna Shervill,Bing S. Gan,Jeffrey C. Howard,Gregor Reid 한국식품영양과학회 2004 Preventive Nutrition and Food Science Vol.9 No.1
Cranberries have long been used by lay people to relieve the symptoms of urinary tract infections. Recent research has determined that the component of cranberry called proanthocyanidin (PAC) is the primary mechanism for inhibiting P-fimbriated E.coli adhesion to uroepithelial cells in vitro. A series of experiments were performed to determine the effects of PAC on growth and adhesion of uropathogenic E. coli and Staphylococcus aureus to urinary catheter material. The results showed that PAC-inhibited binding of Gram positive S. aureus to collagen coated surfaces and significantly decreased the growth of these bacteria. P-fimbriated E.coli did not bind well to the biomaterial and their growth was unaffected by the cranberry extract with the exception of some loss in viability at 1000 μg/mL after 5 to 18 hours of exposure. This is the first report of the potential for cranberries to interfere with the adhesion and growth of S. aureus, a multi-drug resistant organisms responsible for morbidity and mortality especially in hospitalized patients.
Hui, Jonathan,Choy, John,Suwandaratne, Sid P.,Shervill, Jenna,Gan, Bing S.,Howard, Jeffrey C.,Reid, Gregor The Korean Society of Food Science and Nutrition 2004 Preventive Nutrition and Food Science Vol.9 No.1
Cranberries have long been used by lay people to relieve the symptoms of urinary tract infections. Recent research has determined that the component of cranberry called proanthocyanidin (PAC) is the primary mechanism for inhibiting P-fimbriated E.coli adhesion to uroepithelial cells in vitro. A series of experiments were performed to determine the effects of PAC on growth and adhesion of uropathogenic E. coli and Staphylococcus aureus to urinary catheter material. The results showed that PAC-inhibited binding of Gram positive S. aureus to collagen coated surfaces and significantly decreased the growth of these bacteria. P-fimbriated E.coli did not bind well to the biomaterial and their growth was unaffected by the cranberry extract with the exception of some loss in viability at 1000 $\mu\textrm{g}$/mL after 5 to 18 hours of exposure. This is the first report of the potential for cranberries to interfere with the adhesion and growth of S. aureus, a multi-drug resistant organisms responsible for morbidity and mortality especially in hospitalized patients.
A Comparative Evaluation of the Anticancer Properties of European and American Elderberry Fruits
Mary Ann Lila,Julie M. Thole,Tristan F. Burns Kraft,Lilly Ann Sueiro,Young-Hwa Kang,Joell J. Gills,Muriel Cuendet,John M. Pezzuto,David S. Seigler 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.4
European elderberry (Sambucus nigra), recognized in Europe for its health-promoting properties for many gen-erations, is known to contain a range of anthocyanins, flavonoids, and other polyphenolics that contribute to the high antiox-idant capacity of its berries. American elderberry (Sambucus canadensis), on the other hand, has not been cultivated, bred,and promoted as a medicinal plant like its better-characterized European counterpart. In this study, aqueous acetone extractsof the berries from these two species were fractionated and tested in a range of assays that gauge anticarcinogenic potential.Both cultivated S. nigraand wild S. canadensisfruits demonstrated significant chemopreventive potential through strong in-duction of quinone reductase and inhibition of cyclooxygenase-2, which is indicative of anti-initiation and antipromotion prop-erties, respectively. In addition, fractions of S. canadensisextract showed inhibition of ornithine decarboxylase, an enzymemarker related to the promotion stage of carcinogenesis. Analysis of active fractions using mass spectrometry and liquid chro-matography-mass spectrometry revealed, in addition to flavonoids, the presence of more lipophilic compounds such assesquiterpenes, iridoid monoterpene glycosides, and phytosterols.
SYMPOSIA / S13-5 : TRANSCRIPTION REGULATION BY HISTONE ACETYLASES
(D . Steger),(A . Hassan),(K . Neeley),(M . Vignali),(A . Wallberg),(R . Utley),(K . Ikeda),(S . John),(A . Eberharter),(P . Grant),(M . Pray Grant),(A . Wright),(J . Warkman) 한국생화학분자생물학회 (구 한국생화학회) 1999 6th IUBMB SEOUL CONFERENCE Vol.- No.-
Ethephon과 Gibberellin處理가 Concord葡萄 休眠揷穗의 生長과 가지內 貯藏窒素의 變化에 미치는 影響
高光出,姜性模,John S. Titus 서울大學校 農科大學 1981 서울대농학연구지 Vol.6 No.1
The study was carried out to know bud sprouting, shoot growth and total nitrogen of the dormant Concord grape cuttings treated by Ethephon and Gibberlin and assay extractable protein in the dormant canes and August leaves. The results are as follows. 1. Bud sprouting rate of Concord grape cuttings treated Ethephon 10ppm on December 20 was 80% but the rates of untreatment and GA 10ppm were 10~15%. 2. The sprouting rate and shoot growth treated Ethephon on January 21 and February 20 Were lower than that on Dec.20. 3. GA treatment retarded the sprouting and shoot growth of the dormant cuttings. 4. Total mitrogen rate of dormant cane was 0.053~0.083%and it in August grape leaves was 0.115%per fresh weight. 5. Extractable protein in dormant cane was 0.053%~0.083% and it in August grape leaves was 0.115% per fresh weight