임신중기 양수천자에 의한 태아의 세포유전학적 연구

정은환,김학순 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

연구목적: 태아의 염색체 질환을 산전에 진단하기 위한 임신중기 양수천자의 효용성을 분석하고자 하였다. 대상 및 방법: 1995년부터 2002년까지 충북대학교병원에서 임신중기에 양수천자를 시행한 443명의 임부를 대상으로 태아 염색체 검사의 적응증, 이상소견, 및 합병증 유무에 따라 분류하고 비교하였다. 결과: 18명의 임부에서 의미있는 태아 염색체 이상이 발견되었으며 심한 합병증은 없었다. 종류별로는 숫적 이상이 11례, 구조적 이상이 5례, 모자이시즘이 2례였다. 결론: 임신중기 양수천자는 임상적으로 적응증이 되는 경우에는 반드시 시행해야 할 안전하고 정확한 방법임을 확인하였다. Purpose: This study was performed to analyse the efficacy of second trimester genetic amniocentesis for prenatal diagnosis of fetal chromosomal anomaly. Materials and Methods: Fetal karyotype, indications for genetic amniocentesis, and complications were analysed in 443 amniocentesis cases which were performed at Chungbuk National University Hospital from 1995 to 2002. Results: Clinically significant chromosomal abnormalities were found in 18 cases including 11 numerical abnormalities, 5 structural rearrangments, and 2 mosaisms. There was no significant complication. Conclusion: Second trimester genetic amniocentesis is a safe and accurate method to detect fetal chromosomal anomalies and should be performed if clinically indicated.

부산시 일개구 지역주민의 위암선별검사 수검 및 반복수검 실태 및 관련요인조사

정인숙,배은숙,천동환,전진호,이화자,박남희 韓國保健敎育.健康增進學會 2003 보건교육건강증진학회지 Vol.20 No.1

The importance of repeat screening for stomach cancer is well known to decrease deaths from stomach cancer. This study was aimed at assessing practice behaviors and to identify related factors in the aspects of demographic factors, health status and cancer risk recognition, attitude to cancer screening, health behaviors, and inhibiting or facilitating factors to stomach cancer screening in an urban area. Data was collected through self-administered questionnaires from 403 people aged 40 to 69 years from April 23th to May 15th, 2002. Practice behaviors were classified as :"ver"r "ver"and "peat"r "t repeat"rouped based on a recent 5 year screening history. The results were as follows: 1. Among the 403 subjects: "e ever group"as 23.8% and "e repeat group"as 4.0%. The rates of screening were 20.5% for men, 27.8% for those women, and 27.3% for aged 40-49, 24.5% for those aged 50-59, 19.0% for those aged 60-69. The rates of repeat screening were 4.0% for men, 4.1% for women, and 2.9% for those aged 40-49, 6.3% for aged 50-59, 2.5% for those aged 60-69. 2. The main factors associated with adherence to gastric cancer screening were education(post high school vs below : OR=2.44), previous cancer screening(yes vs no : OR=2.61), belief in personal health(no vs yes : OR=2.72), health status(unhealthy vs healthy : OR=3.40), possibility of cancer compared to others(low vs not low : OR=2.56), and regular exercise(yes vs no : OR=2.94). The main factor associated with adherence to gastric cancer repeat screening was other cancer screening (yes vs no : OR=6.33). Consequently, there is a need to change the recognition of the importance and necessity of stomach cancer screening in healthy conditions through health education, and to perform multiple screening tests each visit.

난황낭종 환자에서 보존적 수술 및 항암 화학요법 후 성공적인 자연임신

정은환, 홍승화, 박연진, 지일운, 김학순 충북대학교 의과대학 충북대학교 의학연구소 2012 忠北醫大學術誌 Vol.22 No.1

침윤성 난소암의 경우 생식력의 보존이 중요한 도전이라고 할 수 있다. 20대 중반의 여성에서 거대 한 난황낭종이 발견되어 생식력의 보존을 위해 보존적 수술과 복합항암화학요법을 시행한 후 임신 및 출산에 성공한 증례를 경험하였기에 문헌고찰과 함께 보고한다.

초등학생의 성격유형과 수학적 성향의 관계

김정혜,노은환 晋州敎育大學校 科學敎育硏究院 2006 科學敎育硏究 Vol.29 No.-

MMTIC (Murphy-Meisgeir Type Indicator for Children), which is a tool to measure the inborn psychological functions of children and adolescents, was developed based on Jung's theory of psychological patterns for the use by children and adolescents in their everyday life. We can use the tool to understand differences in personality type among people and to achieve educational goals in the field of education. The purposes of the present study were to survey the distribution of personality type of elementary students in the Sancheong -gun area, which is exposed to natural environment relatively much, to examine the relation between their personality type and their mathematical disposition, and to understand differences in personality type of people and use them for teaching- learning, adjustment to school life, counseling, etc. in the field of education. For these purposes, we formulated research questions as follows. 1. How is the distribution of personality type of elementary students in the Sancheong-gun area? 2. In the personality type of elementary students in the Sancheong-gun area related to their mathematical disposition? 2-1. How are the four preference indexes of personality type related to mathematical disposition? 2-2. How are the four psychological functions of personality type related to mathematical disposition? 2-3. How are the four temperaments of personality type related to mathematical disposition? In order to answer these questions, we surveyed 207 sixth-grade students in six elementary schools in Sancheong-gun, Personality type was tested MMTIC. and mathematical disposition was measured with a test composed of 22 questions, which was developed by the author and the reliability of which was confirmed through a preliminary test. Each question in the mathematical disposition test was on a scale of 4 points. A high score meant high mathematical disposition. MMTIC was analyzed by a special institution, and data for examining the relation between personality type and mathematical disposition were processed using SPSS 10.0. In order to examine the distribution of children's personality type by preference index, by psychological function and by temperament, we calculated frequencies and percentages. In addition, t-test was made to determine the significance of the relation between the preference indexes of personality type and mathematical disposition, and F-test was made to determine the significance of the relations between the psychological functions of personality type and mathematical disposition, and F-test was made to determine the significance of the relations between the psychological functions of personality type and mathematical disposition and between the temperaments of personality type and mathematical disposition. From the results of this study were drawn conclusions as follows. First, when children were compared based on preference indexes, a significantly larger number of students were external(E) in the external-internal(EI) index, intuition(N) in the sensing- intuition(SN) index. feeling(F) in thinking-feeling(TF) index, and perceptive in judging-perceiving(JP) index. In the distribution of psychological functions, intuition- feeling(NF) children were most frequent and, next, sensing-feeling (SF), intuition-thinking(NT) and sensing-thinking(ST) children. In the distribution of temperament, the percentage of children with intuition-feeling(NF) temperament was highest and it was particularly as high as 15.9% among male students and, next, the percentages of children with sensing-perception(SP), sensing-judging(SJ) and intuition-thinking(NT) temperaments in their order. Second, in order to examine the relation of mathematical disposition with the preference indexes(EI, SN, TF, JP) and the psychological functions(ST, SF, NT, NF) of personalty type, we conducted t-test and F-test. According to the results, no statistically significant difference was observed at significance level of 0.05 although there were slight differences of the means in all of the four types. Third, in order to examine the relation between mathematical disposition and the four temperaments (SP, SJ, NT, NF) of personal type, we conducted F-test. According to the results, statistically significant differences were observed at significance level of 0.05 and mathematical disposition was high in order of NT>NF>SJ>SP. Data collected through this research can be a guideline for establishing education plans for elementary students in Sancheong-gun. That is , because there are relatively many students with external disposition in the EI index, education may be focused more on activities. Because there are more students with emotional disposition in the TF index, small- group learning may be emphasized more than individual learning. With regard to the JP index, because most students have perceptive disposition, the tendency may be considered in teaching for higher educational effects. People who prefer the perceptive type generally want to adjust themselves to situations and to live with our restriction, tend to make efforts to understand life rather than control life, adjust themselves at a moment, and like to be openhearted. In addition, as they are fond of various opportunities, they can adapt themselves well to unorganized and uncertain situations. Moreover, they often fail to complete works and to be late in task performance. What is more, whenever such things happen, they usually cope with the situations appropriately by themselves. Understanding students' personality type does not necessarily mean better education. However, it is also absurd to establish education plans and give classes without knowing their characteristics. On the whole, research must begin with the identification of students' unique characteristics so that students' potential for future development can be acknowledged and their development can be promoted properly. Because students' mathematical disposition has a significant effect on their achievement in mathematics, this research began with the identification of students' personality type and explored the relation between students' personality type and their mathematical disposition. Researches should be continued on personality type and various factors affecting students' academic achievements. Such researches will enable customized education.

피부 병변을 동반한 악성조직구증 1예

조은택,박용관,김진호,강정원,천영욱,전익섭,박유환,전춘해 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Malignant histiocytosis, originally described in 1939 as histiocytic medullary reticulosis by Scott and Robb-Smith, is a rare histiocytic proliferative disorder that often shows an acute onset and used to progress to death within a few months. This disorder characterized clinically by fever, generalized weakness, lymphadenopathy and hepatosplenomegaly, and shows a variable range of pancytopenia. Extranodal involvement is common, with an incidence ranging from 50% to as high as 90%, skin involves8ment was noted in 10% to 15%. Typical skin lesions were mainly founded in extremity. i.e. erythematous papule and nodule occasionally become to necrosis and ulceration. We experienced one case of malignant histiocytosis in a 46-years-old female. The major clinical findings are fever, malaise, hepatosplenomegaly and erythematous skin lesion. In the laboratory study, pancytopenia is noted on the peripheral blood. And also aggregation of many atypical histiocytes were shown on skin and bone marrow biopsy. So we reported one related case with malignant histiocytosis as well as reviewing literature .

Ⅱ급 과개교합 환자의 측두근 박리 전 후의 근육활성도에 관한 연구

김은경,김정기,김오환 全北大學校 齒醫學硏究所 1992 전북치대논문집 Vol.10 No.1

The purpose of the present study was to investigate the differences of EMG activity of the masticatory muscles between before and after the temporal muscle detachment from coronoid process in the Class Ⅱ deep bite patients. 12 persons of Class Ⅱ deep bite malocclusion whose mean age 18.4 years served for this study. The EMG data from the anterior temporal and superficial masseter muscles in both sides as mandibular elevators were recorded with the Physiograph MK-Ⅲ electromyographic machine. The EMG recordings were analysed during mandibular rest position, maximal biting and swallowing of saliva. The following results were obtained. 1. There was no significant difference during mandibular rest position and swallowing between before and after temporal muscle detachment at anterior temporal and masseter muscle. 2. The activity of the anterior temporal and masseter muscle during maximal biting showed slightly increase at 8 weeks and 12-24 weeks after temporal muscle detachment, whereas showed significant decrease at 4 weeks after temporal muscle detachment. 3. In comparison of EMG activity during maximal biting between before and 12-24 weeks after temporal muscle detachment showed statistically nonsignificant difference in the anterior temporal muscle, however masseter muscle showed statistically difference(P<0.05).

광양만으로 유입하는 하천하구에서의 이화학적 특성 : 우수기 직후 유입하천에 따른 영향 effect of inputting rivers after rainy season in summer

김은영,정흥호,정호승,조환익,황주찬,최상원 한국환경과학회 2004 한국환경과학회지 Vol.13 No.9

Physicochemical characteristics of Kwangyang Bay, have been investigated on the effects of inputting rivers just after rainy season in summer 2003. The results ranged from 4.96~8.01 mg/L for DO, 1.16~3.09 mg/L for COD, 7.21~67.71 μM for DIN and 0.12~121.84 μM for phosphate. The COD of Yeosu Area was 1.19~3.09 mg/L, Kwangyang Area was 1.23 ~ 2.76 mg/L. The COD of Wallae cheon in Yeosu Area was 3.09 mg/L and Donghoan in Kwangyang Area was 2.76 mg/L. The reason of high COD might be industrial sewage of organic chemical plants and iron foundry. DIN of Yeosu Area and Kwangyang Area were 7.21--63.43 μM and 8.43 67.71 μM respectively. The average phosphate of Yeosu Area was 23.65 μM. The source of phosphate might be industrial sewages of fertilizer plant and phosphate gypsum stocked with high amounts. The metal concentrations were measured in the range of 1.01~175.10 ㎍/L for Cu, 0.13~1.78 ㎍/L for Cd, 1.13~5.21 ㎍/L for Pb, 1.58~13.57 ㎍/L for Cr and 1.07~20.68 ㎍/L for As. The average Cu concentration was 78.99 ㎍/L in Kwangyang Area. The source of Cu might be industrial sewage of iron foundry. The average Cr concentration of Yeosu Area was 9.07 ㎍/L. That is 2 times higher than Kwangyang Bay 5.74 gg/L, because of sewage of chemical plants.

자기평가 활동이 초등학생의 말하기 능력에 미치는 영향

이경은,김정환 한국교원대학교교육연구원 2006 敎員敎育 Vol.22 No.3

본 연구는 자기평가 활동이 초등학생의 말하기 능력에 미치는 영향을 검증하기 위해 첫째, 자기평가 활동이 학생들의 말하기 능력에 어떠한 영향을 미치는가? 둘째, 자기평가 활동이 학생들의 말하기 능력 수준별로 어떠한 차이를 보이는가? 라는 연구문제를 설정하였다. 이 연구문제를 해결하기 위하여 K시 소재 4학년 2개 학급 62명을 실험집단과 통제집단으로 선정하였다. 실험 처치는 본 연구자가 4주간 8회기에 걸쳐 실시하였다. 실험에 투입한 자기평가 도구는 자기점검식 평정방법과 학습 일지 방법을 혼합하여 본 연구자가 제작하였다. 본 연구에서 사용된 말하기 능력 측정 도구로는 말하기 능력 4가지 하위요소에 대해 3점 척도의 자기점검 평정표로 제작한 자기평가지로 동일하게 사용하였다. 말하기 능력은 교사 채점자 3인이 말하기 내용선정, 말하기 내용조직, 표현 및 전달, 자신감 있게 말하는 태도의 각 요소에 대하여 3점 척도의 분석적 평가를 한 후 그 결과를 평균하였다. 말하기 능력은 실험 전인 사전검사와 8회기 자기평가를 적용한 정보를 전달하는 말하기 실험 후의 사후검사, 그리고 4주 후의 지연검사를 통해 측정되었다. 연구에서 얻어진 결과는 첫째, 자기평가 활동이 학생들의 말하기 능력을 향상시켰으나 지속적인 효과는 나타나지 않았다. 둘째, 자기평가는 말하기 능력 상, 중, 하위 집단간 비교에서 상위집단의 말하기 능력을 향상시켰으나 지속적인 효과는 나타나지 않았다. 따라서 본 연구는 자기평가 활동이 장기적으로 이루어진다면 학생들의 수행능력을 향상시킬 수 있는 바람직한 교육적 대안이 될 수 있를 것이다. The purpose of this research was to investigate effects of self-assessment on speaking ability for elementary school students. The research question were as follows ; (1) Self-assessment affect speaking ability? (2) Self-assessment show the difference according to the level of speaking ability? Nonequivalent control group pretest-posttest design was used for this research. Sixty two 4th grade children(actually two classes) were selected for performing experiment. One group was the self-assessment group(n=31) and the other was the control group(n=31). These treatments administered 8 times for 4 weeks in the classroom situation. It took for 40 minutes to complete each experiments. The used instruments were speaking ability test which was scored by three teacher assessors. Means and standard deviations obtained from these tests were analysed with Independent Samples t-test, One-way ANCOVA, MANOVA, MANCOVA. On the basis of the findings of the present study, the following conclusions were made: (1) Self-assessment was effective for the improvement of speaking ability. But the effect of self-assessment did not continue. (2) Self-assessment showed the signifiant difference in accordance with the level of speaking ability. The self-assessment improved speaking ability more positively in high level class than medium level class and low level class. But the effect of self-assessment in high level class did not continue. Consequently, Self-assessment made positive influences on increasing speaking ability. But it is required for improving speaking ability to need the more time training.

조기위암의 형태학적인 분류에 따른 임파절 전이 양상

최은서,강길,박정희,장정환,김권천,김경종,민영돈 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1

Currently, in the limited cases of early gastric cancer (EGC), endoscopic mucosal resection (EMR) is used for curative treatment. However, its completeness is still controversial. The purpose of this study was to review the suggested indications of EMR. We retrospectively analyzed 234 patients with EGC who underwent curative (RO) gastrectomy. The enrolled cases were further classified into mucosal and submucosal types, and mucosal EGC were further classified according to the size, gross type and histologic pattern. 133 patients had mucosal cancers and 101 patients submucosal. The overall incidence of positive lymph node was 14.1% (33/234), the incidence of mucosal cancer was 8. 3% (11/133), which was significantly lower than that of submucosal, 22% (22/101). Of 133 patients with mucosal EGC, 90 were smaller than 2㎝ in size and the incidence of lymph node metastasis was 5.6% (5/90), compared to 43 of larger than 2㎝ with the incidence of 14% (6/43). According to the gross type classification of mucosal cancer, incidence of lymph node metastasis in protruded type (EGC type Ⅰ, Ⅱa, Ⅰ+Ⅱa) was 15.4% (4/26), nat type(EGC type Ⅱb) 2. 9% (1/35), depressed type (EGC type Ⅱc, Ⅲ) 8.3% (6/72). Lymph node metastasis in differentiated type of mucosal cancer was 6.9% (5/72) and undifferentiatcd type 9.8% (6/61). In this study, there was no single indication free from lymph node metastasis, It is thought that the selection of EMR for the curative treatment of EGC should be considered carefully and more clinical studies with long-term follow up are necessary for EMR to be generally acceptable.

결장직장암 환자의 임상적 고찰 : 조선대학교 부속병원의 10년 간의 결과

나은종,문성표,장정환,김권천,민영돈,김성환,조현진,김정용,김경종 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Background and Objectives: The colorectal cancer rates 4th in the total cancer prevalence in Korea. The clinical patient demographics were considered with the incidence rate of the colon and rectal cancer. The clinicopathological factors were analyzed for the 5 year survival rate. Materials Methods: Of the 282 patients who were operated from Jan. 1, 1992 to Dec. 31, 2001 and diagnosed by pathological biopsy as colo-rectal cancer, 234 patients were followed up. The age, sex, location of the cancer, TNM stage, operation method, histopathological classification, metastatic region, complications after operation and the survival rate were investigated. Results: Of the 234 patients, male and female consisted of 120 cases (51.3%) and 114 cases (46.7%), with an average age of 61.6 years. The average follow up period was 52.3 months and the peri operative mortality was 5.6%. The site of the cancer was most frequent at the rectum with 127 cases (54.3%). The patients were classified according to the TNM stages with 38 cases of stage 1 (16.2%), 98 cases of II (41.9%), 72 cases of III (30.8%) and 26 cases of IV (11.1%). The 5 year survival rate in the age group older than 50 was 63.3 % and 73.5% in the group younger than 50. In regard to the operation type, the 5 year survival rate was 65.4% for elective operation and 65.8% for emergency operation. The 5 year survival rate for well differentiated, moderately differentiated, poorly differentiated cancer, and mucinous adenocarcinoma was 73.7%, 60.2%, 58.3%, and 92.6%, respectively. The 5 year survival rate of each of the TNM stage is 81.1%, 74.8%, 57.0%, and 11.5% for Classes I, II, III, and IV, respectively. Conclusion: The clinical factors were analyzed for the 5 year survival rate with no statistical significance for the age, sex, and location of the cancer. The TNM stage and histopathological differentiation were statistically significant. The colon cancer showed better prognosis compared to the rectal cancer.