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치주질환에 있어서의 조직파괴인자 및 억제약물에 대한 연구
김오환,김형섭,오귀옥 대한구강생물학회 1988 International Journal of Oral Biology Vol.12 No.2
Arachidonic acid(AA) metabolites are known to play an important role in the development of inflammation and pathogenesis of periodontal disease. The bone resorbing activity of PGE_2 and elevated level of prostaglandins and thromboxane in inflamed gingiva, which are cyclooxygenase(C) products, has been well documented. However, since recent studies provide evidence that gingival tissue metabolizes AA mainly through lipoxygenase(L) pathway, we have started this study to show the exact profile of AA metabolism in gingival tissue. Fourteen individual periodontal pocket tissue(PPT) samples were obtained from patients with advanced periodontitis and incubated separately with ^14C-AA(0.2μCi). The tissue lipid extracts were separated by means of thin layer chromatography(TLC), and analyzed by means of autoradiography and TLC analyzer. Our work show that ^14C-AA metabolism in PPT is mainly via the L pathway(L products/C products=6.17) and that 12-HETE & 15-HETE(55.73% of total formed metabolites), to a lesser extent 5-HETE(6.21%), are the major L products formed. C products thromboxane B_2 (4.32%), 6-keto-PGF_1α & PGE_2 (4.42%) were also detected in much smaller amounts than L products. Indomethacin well-known C inhibitor, also inhibited L as well as C, that is the result similar to the reports of Paajanen et al.(1982) and Lessard et al.(1986). This phenomenon is being further investigated by use of partially purified L system.
김오환 전북대학교 의과학연구소 1982 全北醫大論文集 Vol.6 No.1
The purpose of this investigation was to make a evalutation of the oral health of orthopedically handicapped children by considering the DMF rate, simplified debris, calculus, and hygience index of 44 orthopedic children. 1. The DMF rate of all examined children was 65.09% 2. Oral hygiene status of orthopedically haudicapped childredn was very poor and became worse by aging.
ECT (European Compression Technic) System 을 사용한 下顎骨 骨折의 治驗例
金晤煥,申曉根,宋采炫,崔秉河,權泰鎬 全北大學校 齒醫學硏究所 1983 전북치대논문집 Vol.1 No.1
The authors in the Dept. of Oral & Maxillo-facial Surgery.J.N.U Hospital could have the following results after treatment of eight mandibular fractures patients with the E.C.T.(European Compression Technic)System. 1. Accurate reduction of the fractured bone. 2. Minimization of the soft tissue injury during operations. 3. No post-operative intermaxillary fixation was necessary. 4. Good recovery of the occlusion.
金晤煥 전북대학교 의과학연구소 1978 全北醫大論文集 Vol.2 No.-
In order to establish a basic data for the public dental health in the islands in West sea of Jeonlabugdo, the author has studied epidemiologically the teeth brushing frequency, D.M.F, and D.M.F.T, in the permanent teeth in 945 school boys and girls aged from six to sixteen years during the period from August to November in 1977. The obtained results are as follows : 1) Of examined students, 2.65% was brushing the teeth twice per day, 30.69% was once per day, 34.71% was seldom, 31.69% was no teeth brushing. 2) D.M.F. was 25% in the age of 6 years, 52.94% in the age of 9 years, 86.49% in the age of 16 years. 3) D.M.F.T, was 0.71% in the age of 6 years, 1.92% in the age of 9 years, 3.28% in the age of 12 years, 4.95% in the age of 16 years. 4) The teeth brushing frequency of examined students became increased by aging. 5) D.M.F. and D.M.F.T. of examined students became increased by aging.