조혈모세포이식 환자에서 발생한 Cytomegalovirus 질환의 특징 : 일개 대학변원에서 최근 10년간의 경험

최수미,이동건,박선희,김시현,김유진,민창기,김희제,이석,최정현,유진홍,김동욱,이종욱,민우성,신완식,김춘추 대한감염학회 2009 감염과 화학요법 Vol.41 No.1

Background : Studies on cytomegalovirus (CMV) diseases in Korean hematopoietic stem cell transplant (HSCT) recipients are lacking and do not reflect the recent trends of advances and changes. Therefore, we tried to analyze the clinical features of CMV diseases in HSCT recipients over the past 10 years at a tertiary university hospital in Korea. Methods : Retrospective review of medical records was done for all adult HSCT patients who received transplant at the Catholic HSCT Center from January 1998 to January 2008. Results : Forty-four cases (2.2%) of CMV diseases were identified. CMV pneumonia was diagnosed in 17 patients, retinitis in 16 patients, enterocolitis in 7 patients, esophagitis 1 patient, gastritis in 1 patient, duodenitis in 1 patient, and hepatitis in 1 patient. The median onset of symptom was 90 days after transplantation. Late CMV diseases accounted for 47.7%. CMV related death varied from 0 to 58.8% according to the involved organ. CMV retinitis was diagnosed relatively later in the course of transplantation mostly in patients who had chronic graft versus host disease (GVHD). On the contrary, CMV enterocolitis mainly occurred in patients who suffered from acute GVHD. The overall concurrent CMV reactivation was documented to be 63.6%: the concurrent CMV reactivation was observed only in 37.5% of patients with retinitis. Conclusions : We observed some differences in the pattern of CMV disease manifestation according to the involved organ and reconfirmed the fact that CMV pneumonia is the most common and fatal disease in HSCT recipients. Additionally, CMV retinitis was not uncommon in HSCT recipients. Since specific marker does not exist in predicting retinitis, regular ocular examination should be done thoroughly, especially in patients with chronic GVHD.

성인 지역사회 폐렴의 원인 미생물에 대한 전향적 다기관 연구 : Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi

김민자,정희진,손장욱,심희선,박대원,박승철,우준희,강재명,김유겸,신완식,김양리,이환종,김지희 대한감염학회 2001 감염 Vol.33 No.1

Background : Despite rigorous investigations, the etiology of community-acquired pneumonia remains unknown in about 50% of hospitalized patients. The diagnosis of the etiological agent is becoming more challenging and more critical as number of newer pathogens have been recognized in recent years. In the 3-year period prospective study we investigated adult patients with community-acquired pneumonia for Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi as potential etiologic agents. Methods : A prospective multicenter study was performed from May 1997 to April 2000. A total of 431 patients with community-acquired pneumonia under the inclusion criteria were examined for specific microbial diagnosis; sputum culture and PCR, and serologic teats including indirect immunofluorescence antibody (IFA) test for Legionella, and hemagglutination tests for Leptosoira, Hantaan virus and O. tsutsugamushi. Etiologic diagnosis was determined on the basis of the review of case record forms and specific laboratory diagnostic criteria. Results : During the study period a total of 385 sputum and 283 serum samples were examined. Legionella pneumonia was diagnosed in 2.3% (10/431) of the cases examined : 1.4% cases with PCR-positive (5/367) and 2.1% with positive IFA test (6/283). Leptospirosis and scrub typhus were diagnosed in 0.4% (1/252) and 2.0% (5/252), respectively. All 5 cases with scrub typhus occurred in late fall, and rash or eschar was not found. None of cases was Hantaan virus infection. Conclusion : The results suggest that Legionella, Leptospira, and O. tsutsugamushi should be considered in the etiologic diagnosis and empirical antibiotic therapy of community-acquired pneumonia. (Korean J Infect Dis 32:24∼31, 2001)

아미노산 투여가 중장거리 운동선수의 최대 및 최대하운동시 젖산생성에 미치는 영향

이정수,윤탁영,김문희,이선장,김완조 韓國體育大學校附屬 體育科學硏究所 1992 韓國體育大學校附屬 體育科學硏究所論文集 Vol.11 No.1

The Purpose of the Study was to determine whether the glutamate ingestion prior to exercise would reduce the lactat formation and its clearance in exercising mscle tisue during Submaximal and maximal execise. Six elite distance rummers particapated in this study. The Subjects had a half dose of glutamale(15.6mg .Kg?? ??) at 45min and ingested rest dose at prior to exerise. The test Performed twice. One was Performed in the track and the other was in the Lab. Blood Smples were obtained from catheter which was placed in the antecubital vein (Lab test) and finger tip Samples (Feld test) Unaltered blood lactate was observed in both trials, but, tended to less lactate concentration with glutamate ingestion than that of without glutamate ingestion. The recovery rate of blood lactate was markely rapid with glutamate ingestion in the field test. Unchanged in heart rate was founded in both trials. It many Suggest that, the additional supplement st of glutamate can improve execise performance limiting lactate formation or induce its rapid clearance from the muscle fissue.

Virgin Abdomen에서의 장폐쇄증

이희만,송인상,윤완희 대한대장항문학회 1994 Annals of Coloproctolgy Vol.10 No.2

지역특성에 따른 국민학교 육상경기의 지도실태에 관한 분석연구 : 강원도내 국민학교를 중심으로

이완희 춘천교육대학교 초등교육연구소 1989 敎育硏究 Vol.7 No.-

Conclusion and suggestion : This study has been conducted through the writer's visits to 87 primary schools in Kangwon-do province and through guestionaire on teaching field and track and raising to players from those schools. The schools were divided into 5 groups consisting of 15 schools in urban areas, 13 schools in agricultural areas, 13 schools in mining areas, 19 schools in reaote rural areas, 21 schools in areas adjacent to DMZ. the results of the writer's results of the writer's analysis are : 1. The general results teaching of field events showed more difficulty than that of track events regasdless of areas. 2. The teaching of track events showed difficulty in the order of hurdle races, long distance races, short distance races, middle distance races, and relay races. 3. The teaching of field events showed the most difficulty in high jump events. 4. The problems in teaching field and track events arise grom insuffgicient teaching methods, facilities, and sporting goods. 5. The most necessary facilities and sporting goods in teaching field and track were : 66.67% in high jump, 32.18% in track and straight line track, which are basic. The most serious areas are mining areas, remote rural areas, and areas adjacent to DMZ. 6. The normal operation of field and track events was not available in 89.66% the schools regardless of areas. 7. According to the regional conditions, the problems arise from these factors : in the problems of teaching field and track, urban areas suffer from large classes, agricultural areas from shortage of leaders, and inzmining areas, remote rural areas and areas adjacent to DMZ. 8. 87.36% of field and track umpires and leaders had no experience of participating in workshops. 9. In some schools field and track players were selected through races in schools grounds and teachers recommendations regardless of areas. 10. The responses from the parents of field and track players were generally natgative : urban areas showed 93.33% while mining areas 46.15%. 11. The problams in teaching and raising field and track players arose from these : urban areas suffered from limited ground space because of other events and parents' opposition, agricultural areas from insufficient player resource and budget, miming areas from pollution and freguent pupil transference, and remote rural areas and areas adjacent of DMZ from long cold winter and geavy fall of snow and limited training hours because of short shining hours. There are suggested : Field and track events which are basic and compulsory in physical education become unpopular events, that they are neglected by both pupils and parents. It is suggested that (1) these problems arising from regional conditions he solved immediately, (2) positive public relation be inplemented, (3) development and spread of audio-vidual aids suitable for teaching and developing field and track events he fulfilled, (4) appropriate workshops for in-service teachers he conducted.

國民學校 高學年의 100m 疾走能力 分析 硏究

李完熙 春川敎育大學 1983 論文集 Vol.23 No.-

교육대학교 대학원 예체능 교육과정에관한 연구

이완섭,김정희,유원 춘천교육대학교 예체능교육연구소 1987 예체능교육연구 Vol.2 No.-

중국에서 이식한 종어 (Leiocassis longirostris Gunther)의 외부 형태 및 초기생활사

이완옥,김경환,김대희,조용철,김응오 한국어류학회 2004 韓國魚類學會誌 Vol.16 No.1

한국에서 절멸된 것으로 알려진 종어 (Leiocassis longifostris)를 국내에 복원하고, 양식대상종으로 개발하기 위하여 중국에서 도입하여 외부형태를 비교하고, 난발생 과정 및 부화자어의 형태를 연구하였다. 도입된 표본의 계수·계측형질을 국내와 중국에 알려진 문헌과 비교한 결과 큰 차이를 보이지 않았다. 중국에서 도입한 암수 한쌍의 성어에서 채란하였고, 습식법으로 수정하였다. 수정란의 크기는 2.01∼2.10 mm(n=10)이었으며, 알의 형태는 원반형이고, 난막은 무색투명하였으며, 강한 접착력이 있었다. 난황은 담황색이고 유구는 없었다. 수정 1시간 후에 배반이 완성되었고, 1시간 30분 후에 난할이 시작되었다. 수정란의 수온을 21.5∼23.0℃로 유지할 때 30∼50분 간격으로 이후 난할이 계속되었다. 수정 후 상실기는 6시간에 도달하였고, 낭배기는 20시간 20분 후에 완성되었다. 난황 표면에서 관찰되는 특이한 연동운동은 상실기에 시작되어 포배기 말기인 30% epiboly기까지 계속되었다. 수정 75시간 후에 부화에 이르렀고, 부화 직후 자어의 크기는 전장 5.91∼6.10 mm 이었다. 부화 3일 후에 입이 열리고, 수염과 부레가 완성되었으며, 전장 9.07 ∼9.37 mm까지 자랐다. 부화 15일후에는 모든 지느러미가 완성되어 후기자어기 상태이었고, 전장 14.80∼16.50 mm로 자랐으며, 부화 25일 후에는 체형, 체색 그리고 생활습성 등이 성체와 유사하고, 전장은 18.59∼22.35 mm까지 성장하였다. The Long-snout bullhead, Leiocassis longirostris, is an introduced fish from China which had become extinct in Korea. Its morphological characteristics and early life history was studied to obtain useful information required for restoration of the species and also for its utilization as an aquaculture fish. Measurements and counts of specimens introduced into Korea were included in the range of those taken from the known literature of Korea and China. Eggs were obtained by fertilization by wet method in the laboratory using one mature male and female adults of introduced L. longirostris. The fertilized eggs measured 2.01-2.10 ㎜ (n = 10) in diameter. The eggs were diskshaped and strongly adhesive, with colorless transparent membrane. The yolk was pale yellow in color with no oil globule. The blastodisc was formed in about 1 hour and cleavage started around 1 hour 30 minutes after fertilization. The cleavage intervals were about 30-50 minutes at 21.5-23℃. The morula stage was reached at 6 hours, and gastrulation was completed at 20 hours 20 min. after fertilization. Peristalsic movements of the yolk surface started at the morula stage and continued to the blastula stage (30% epiboly). Hatching occurred 75 hours after fertilization, and newly hatched larvae were 5.91-6.10 ㎜ (n = 10) in total length (TL). The mouth was open, and barbels and the air-bladder were completely formed 3 days after hatching, at 9.07-9.37 ㎜ TL. All the fin rays were completely formed and the larvae became a postlarva 15 days after hatching at 14.80-16.50 ㎜ in TL. Body shape, color pattern, and habitat behavior were similar to those in the adult at 25 days after hatching and a size of 18.59-22.35 ㎜ TL.

高校生의 100m 疾走能力 分析 硏究

李完熙 春川敎育大學 1985 論文集 Vol.25 No.-

I studies for the 100r3 running ability of the students in the High School. This study is purposed on the Surveying of the factors to be needed for the inprovement on the running record and on the materials which can be used in the fields of education, Two hundred and forty three students(boys and girls in the all grades of C. boys highschool and C. girls high school in chun cheon.) served as assubjects. They were tested and analyged during septemter, 17-22, 1984. The results are as follows ; As shown in the above 1. The boy-students were faster than the girls in average running records in each section without relating to their ages. 2. The boy-students speed average also faster than the girls in each section. 3. The total numbers of the step3 for the boys were less frequency than for girls in each section without relating to their ages. 4. The average distance per step of the boys lager than of the girls in each section without relating to their ages. 5. The speed maintenance rate of the girls, except the case of 18 years, was higher than of the boys. 6. The speed deceleration rate of the girls, except the case of 18 year3, was lower than of the boys. 7. The speed acceleration rate of the boys higher than of the girls without relating to their ages.

國民學校 低學年의 100m 疾走能力 分析硏究

李完熙 春川敎育大學 1982 論文集 Vol.22 No.-