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      • 현대 한옥 범주의 주거공간에 적용된 재료에 관한 연구

        주한나(Ju, Han-Nah),이현수(Lee, Hyun-Soo) 한국실내디자인학회 2013 한국실내디자인학회 학술대회논문집 Vol.15 No.1

        Hanok has become popular in public since 2000, as issue of eco design has grown rapidly among architecture field. The range of materials has to be categorized and defined in order to apply in interior spaces. The following results are defined; Three elements are selected from five categories from the references as Modern Hanok; Hayllu(Korean wave) Architecture, Han-style Architecture, and Hanok of Architect. Total 6 cases(2 for each category) was analyzed in a material framework which is consisted on wood, fabric, polymer, metal, nonferrous metal, stone, cement, plastic clay, glass, painting. Most of materials are used in Hallyu(Korean wave) architecture and Han-style Architecture except for a stone in interior spaces. On the other hand, most of wood and fabric are used in Hanok of Architect even though plastic clay, glass, and painting are rarely used. Materials can be used widely for a foundation of source if more specific investigation is defined and categorized and increasing numbers of study.

      • 사람 갑상선자극호르몬 수용체를 발현하는 Chinese Hamster Ovary(hTSHR-CHO)세포를 이용한 자극형 갑상선자극호르몬 수용체 항체 활성 측정의 임상적 유용성

        한희정,원진호,채수홍,김현진,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

        Detection of thyroid stimulating hormone receptor(TSHR) autoantibodies has clinical value in establishing the diagnosis of Graves ' disease, and in predicting its clinical course with high sensitivity and high specificity. Especially, TBII using radioreceptor assay has been widely used. Recently, for detecting thyroid stimulating antibody(TSAb), a sensitive method using human TSH receptor-transfected Chinese Hamster Ovary(CHO) cells has been developed and clinically used. The aims of this study are to determine the change and discrepancy of 2 TSHR autoantibodics in clinical course and to evaluate the correlation between 2 autoantibodies. We measured TSAb and TBII in 30 newly diagnosed and untreated patients and in 73 previously diagnosed as Graves ' disease and treated with antithyroid drug. Also we compared the changes of the antibodies in clinical course and correlation between 2 antibodies. Thes results are summarized follows. 1. In newly diagnosed patients, all of the 30 patients had positive TBII and/or TSAb. None of them had negative TBII and negative TSAb. And in newly diagnosed patients, mean TBII and mean TSAb values are 46.8% and 361%, respectively. In 73 treated patients mean values are 18. 7% and 196% each other. Therefore, newly diagnosed group has significant greater TBII and TSAb than antithyroid drug-treated group. 2. TBII was significantly different between euthyroid group and thyrotoxic group in antithyroid drug-treated patients, but TSAb was not. 3. TBII was sequentially decreased as increased medication duration, but TSAb was not shown sequential decrease as increased medication duration. 4. There was significant negative correlation between cumulative doses of antithyroid drug and TBII, but no significant correlation between cumulative doses and TSAb. 6. There was significant positive correlation between TBII and TSAb in total patients group and in antithyroid drug medication group, but not in newly diagnosed group. In conclusion, in Graves ' disease patients, detection of TSHR antibodies are clinical values in establishing the diagnosis and prediction of clinical course. A method detecting TSAb using hTSHR-CHO cells should be further studied for standardization of measurement, and for detecting the changes of TSAb in clinical course, long-term follow-up of patients are important.

      • 경악 반응 측정법

        한정수,김현택 한국심리학회 2005 한국심리학회지 생물 및 생리 Vol.3 No.1

        강한 소리자극이나 공기분사에 의해 피험동물에게서 유발된 경악반응을 기록하는 측정장치인 안정계를 소개한다. 이 장치는 동물의 움직임을 매우 민감하게 감지할 뿐만아니라 변환기로서 규격품의 스피커를 사용하므로 다수의 장치를 동시에 사용하여도 민감도에 있어서 장치간의 차이가 없다. 또한 경악반응을 유발시키기 위한 강한소리 발생장치와 경악반응의 기록 및 분석을 위한 컴퓨터 인터페이스 기술에 대해 설명한다. This report introduces the stabilimeter with a loudspeaker which measures startle reaction induced intense auditory stimulus or air puff. This apparatus provides high sensitivity, good reproductivity and a wide range of utilization(rat and mice). Also a device that elicits the statle reaction by auditory stimulus and a computer's interface that records and analyses the startle responses are introduced.

      • KCI등재

        통일을 대비한 남북한 도서관 정책과 제도에 관한 연구

        한상완,김태수,전현주,이승채 한국문헌정보학회 1996 한국문헌정보학회지 Vol.30 No.1

        동서간의 냉전을 종식하고 탈 이데올로기 시대에 돌입한 세계정세는 체제와 이념을 극복하고 자국의 경제적 이익과 국민의 복지를 중심으로하여 자국 우위의 경제 중심으로 변해가고 있다. 이러한 세계 정세속에서 경쟁력을 확보하고 분단된 민족의 화합을 위하여 남북한이 통일되어야 할 것이다. 남북한이 통일되면 문명의 큰 흐름이 정보사회로 변전하는 이때에 정보를 효과적으로 수집, 가공, 축적, 제공하는 제도적 장치인 도서관 정책과 제도를 어떻게 운용할 것인가 하는 과제는 국가의 중대사이다. 그런 관점에서 이 연구는 다음과 같은 결론을 얻었다. 첫째, 통일을 대비하여 민족도서관을 건설하는데 있어서 1)정보사회형 정책과 제도 개념 2)민족문화중심의 정책과 제도개념을 도입하는 것이 필요하다. 둘째, 통일에 앞서 우선적으로 남북한 도서관간의 협력구도를 마련하는 것이 필요하다. 이러한 협력은 종합목록의 작성, 자료의 상호대차, 자료의 공동활용을 위한 표준화된 목록규칙의 작성, 학위논문의 교환 등과 같은 실질적 이익을 가져다 주는 부분에서부터 시작해서 점차 자원을 필요로 하는 영역으로 확산되어야 한다. 셋째, 통일을 대비한 도서관 정책과 제도를 개발하는 일은 지배 모델로서의 통합흡수형이 아닌 상호의존 모델로서의 병존협력의 개념위에서 수행되어야 한다. 넷째, 통일을 대비한 도서관 정책원리에는 1)자유경쟁의 논리 2)사회교육을 통한 의식의 개혁 3)자주의식과 인류애 4)과학적 내지는 합리적 사고 5)직업에 대한 소명의식 6)민주시민정신 7)공동체의식 8)공익정신 9)세계정신을 포함시킬 것이 요구된다. 다섯째, 통일을 대비한 도서관 제도모형은 남북한의 도서관이 1)도서관의 위상통일 2)도서관 정책 및 제도 전문연구기관의 설립 3)전문인력의 교류 4)정보자료의 교류 5)학술정보망의 구축 6)문헌정보학 교육체계의 확립과 수준향상 7)현대화 및 정보기술 개발과 이양 등을 내용으로 갖추고 그 구체적인 사안들을 공동개발할 필요가 있다. 끝으로, 남북한의 도서관은 그 개념, 운영목적, 자원의 내용 및 이용방법 등이 모두 상이하다고 할 수 있다. 도서관의 존재이유와 그 실용성의 측면들을 고려할 때, 남북한의 도서관은 통일이라고 하는 사회적 변화에 직면하여 그 충격이 최소한의 것이 되도록 상호 공조체제를 구성할 필요가 있다 The world has moved from the Cold War between the east and the west, and moved toward the age without idealogy. It places emphasis on economic benefit and welfare of its own nation as its main point. With this world trend, in order to secure the competitiveness and the reconciliation of the divided nation, the north and the south Korea should be united. Once the north and the south are united, information society will be altered with the huge flow of the civilization. At the same time, the issue of how to operate library policies and system, in which effective acquisition, manipulation, accumulation, and dissemination of information occurs, would be very important. From this point of view, the following conclusions are obtained in this study. Firstly, when building a national library preparing for the national unification, it is essential to introduce 1)the concept of policy and system for information society and 2)that of policy and system which has national-culture as its focus. Secondly, it is essential to prepare the cooperative-structure between libraries prior to the national unification. This kind of cooperation should gradually expand to an extent that allows actual benefits such as building union catalog, inter-library loan system, resource sharing, standardized cataloging rules, and exchange of dissertation... etc. Thirdly, developing the library policies and systems for the national unification must be based on the concept of the mutual cooperation as inter-dependent model, rather than on the concept of the incorporation-absorption as a dominant model. The next point, the principles of the followings in preparing the library policies should be considered: 1)free-competition, 2)revolution of consciousness through the social education, 3)independence and love for humanity, 4)scientific or reasonable thinking, 5)job responsibility, 6)democratic citizenship, 7)mind for collective life, 8)spirit of public interest, 9)globalization In addition, the model of the library systems preparing for the national unification should include the followings: 1)uniformity of library system and its authority, 2)establishment of research institutes for library policy and system, 3)exchange of library experts and information resources, 4)building library networks, 5)establishment of education systems for the library and information science and enhancement of its quality, 6)modernizing and developing information technology and its transfer. Finally, the libraries in the north and the south has different concepts, goals, information resources, and the different ways of using them. Considering the practical aspects of the libraries and the reasons for their existence, they must structure the mutual cooperative system so as to minimize the shock when confronting the social changes, so-called the national unification

      • KCI등재

        실시간 주문 확답을 위한 데이터 마이닝 기반 운용 계획 모델

        한현수,오동하 한국경영과학회 2004 經營 科學 Vol.21 No.3

        In the rapidly propagating Internet based electronic transaction environment, the importance of real time order confirmation has been more emphasized. In this paper, using data mining techniques, we develop intelligent operations decision model to allow real time order confirmation at the time the customer places an order with required delivery terms. Among various operation plannings used for order fulfillment, mill routing is the first interface decision point to link the order receiving at the marketing with the production planning for order fulfillment. Though linear programming based mathematical optimization techniques are mostly used for mill routing problems, some early orders should wait until sufficient orders are gathered for optimization. And that could effect longer order fulfillment lead-time, and prevent instant order confirmation of delivery terms. To cope with this problem. we provide the intelligent decision model to allow instant order based mill routing decisions. Data mining techniques of decision trees and neural networks, which are more popular in marketing and financial applications, are used to develop the model. Through diverse computational trials with the industrial data from the steel company, we have reported that the performance of the proposed approach is effective compared to the present heuristic only mill routing results. Various issues of data mining techniques application to the mill routing problems having linear programming characteristics are also discussed.

      • 쌀, 조, 수수 및 콩의 食餌가 흰쥐의 成長 및 血液性狀에 미치는 影響

        한백수,주현규,사동민,박병순,박기웅 선문대학교 첨단과학기술연구소 1996 첨단과학기술연구소 논문집 Vol.1 No.1

        쌀, 조 수수, 및 콩의 식이가 흰쥐의 성장 및 혈액 성상에 미치는 영향을 조사하기 위하여, 평균체중 180g의 Sprague-Dawley계 rat(♂) 각 5마리씩을 대조군(T_(0)), 쌀(T_(1)), 조(T_(2)), 수수(T_(3)), 콩(T_(4))급이군등 5개군으로 나누어 실온에서 6주간 사육하면서 사료섭취량, 급수량, 증체량과 6주후의 혈액상의 변화틀 조사하였다. 사료 섭취량은 대조군이 각 처리 실험군보다 높았으며 물의 급수량도 동일한 결과이었으며 그 순위는 쌀, 조, 콩, 수수 순으로 감소하였으며, 각 처리군의 증체량은 대조군 보다 낮았으며, 특히 수수는 초기보다 감소하였고, 각 처리군의 사료효율은 대조군보다 낮았으며 특히 수수처리군이 타 처리군보다 낮았다. 연액성상의 변희는 대조군에서는 큰 변화가 없으나 수수군에서 BUN, HOT지 다른군보다 높았으며 쌀의 처리군은 creatinine치가 높았고 조에서는 혈당치가 낮았으며, 콩에서는 LDH는 높았고, HGB, HCT, PI.T, RBC가 낮았고, 특히 콩 수수에서는 혈액상의 변화가 가장 컸으며 다른 실험군과 비교하였을 때 통계적인 유의성이 인정되었다. This study was conducted to investigate the effects of rice, millet, sorghum and soybean diet on the growth rate, daily intake feed ratio and change in hematology of male rats. The experimental male rats of 180g average weight were fed on control (T_(0)), rice (T_(1)), millet (T_(2)), sorghum (T_(3)) and soybean diet (T_(4)) for 6 weeks. The amount of daily feed and water intake supply in each diet group is higher than that of control group to as shown in the following order: rice, millet, soybean, sorghum. The growth ratio of each diet group is lower than that of control group. Especially, sorghum made each diet group reduce the weight even more than the initial weight. Control group is lower than each diet group in regard to the effective ratio of feed. Especially, the sorghum group is lower than other groups. Control group remained same in the change of hematology, however, sorghum group is higher than other groups for BUN, HCT. Rice group is higher in creatinine and millet group is lower in glucose content of serum than any other groups. Soybean group is higher in LDH but lower in HGB, HCT, PLT, RBC than control group. Especially, the soybean and sorghum groups showed a big change in hematology and had the statistic significance in comparison to other groups.

      • 치아재식후 치유과정에서 fibronectin의 분포에 관한 면?조직화학적 연구

        한휘철,김현수,주성숙,신제원 慶熙大學校 齒科大學 1995 慶熙齒大論文集 Vol.17 No.2

        Periodontalhealing requires the formation of new periodontal tissues comprised of various extracellular components. The present study investigated the formation and distribution of the fibronectin FN), a major adhesive glycoprotein. Rats weighing 130`150 gm were fed 0.4% R -aminopropionitrile for 5 days to achieve gentle tooth extraction. The maxillary first molars were extracted under anesthesia with pentobarbital, washed in sterile distilled water, treated with bacterial collagenase to digest collagen fibers on the root surfaces. After washing in water overnight, the mesial root surfaces were demineralized by application of citric acid, washed, dried and stored at 4 t. Immediately after tooth extraction and bleeding control, the treated molars extracted previously from other rats were reimplanted. Ten animals each were sacrificed 45 min, 1, 3, 6, 10 days after reimplantation of teeth by intracardiac perfusion with 4% paraformaldehyde. The replanted molars and surrounding tissues were cut, demineralized, dehydrated and embedded in paraffin. Imrnunostaining of the FN was achieved by the avidin-biotin complex method. The results as follows; 1. The control group showed gradual healing from 1 day and complete regeneration of the periodontium at 10 days. 2. At early healing stage, intense staining for FN was observed in the newly formed connective tissues, granulation tissue, especially around blood vessels as well as inflammatory cells. 3. At later healing stage, FN was expressed later in the periodontal ligament, cementum, osteoid, and newly formed connective tissue and its attachment site to the root surface. 4. Strong immunolabeling for FN was found in cementoblasts, osteoblasts, and new bone and cementum, which weaken staining was observed on the dentin and alveolar bone. 5. These results suggest that the healing after replantation is achieved through a series of cell differentiation and formation of FN.

      • KCI등재후보

        저장기간에 따른 3개 수종의 종자 및 발아 특성 변화

        한심희,김찬수,장석성,이현주,탁우식 한국농림기상학회 2004 한국농림기상학회지 Vol.6 No.3

        This study was conducted to examine the changes in the seed physical characters and germinative properties of three tree species at three different storage times in order to determine the most suitable storage time and condition. Seed physical characters and germinative properties were examined from seeds of Fraxinus rhynchophylla, Zanthoxylum schinifolium and Staphylea bumalda that were stored at -18C for 1, 3 and 10 years, and the growth performance and physiological characters of their seedlings were analyzed. Seed physical characters and germinative properties showed significant differences between three storage times as well as three tree species. Seed moisture content of F. rhynchophylla and S. bumalda and seed fresh weight of Z. schinifolium decreased with increase of storage time. Storage time represented negative correlation with moisture content and fresh weight (r = -0.822, p < 0.01). Seed percent germination of Z. schinifolium and S. bumalda stored for 3 and 10 years decreased less than 15% and 10.7% respectively. Mean germination times for seed of F. rhynchophylla, Z. schinifolium and S. bumalda were delayed 11.9, 5.7 and 9.7 days after a storage time of 10 years, respectively. However the growth and viability of seedlings didn't show a special pattern for storage time and tree species.

      • 칼슘 통로 봉쇄제가 Pilocarpine에 의한 경련 및 기억장애에 미치는 영향

        한형수,배현혜,박정숙,김중영 慶北大學校 醫科大學 1996 慶北醫大誌 Vol.37 No.3

        목적 : 칼슘 통로 봉쇄제인 nifedipine과 flunarizine이 pilocarpine으로 유발된 경련의 발생과 뇌 조직 손상으로 인한 기억력 저하에 어떤 영향을 미치는지 연구하고자 하였다. 대상 및 방법 : ICR계의 생쥐 수컷을 사용하여 pilocarpone 투여후 6단계로 나누어 경련발작을 관찰하였으며, nifedipine과 flunarizine 전처치후 pilocarpine 투여에 따른 항경련작용을 측정하였다. Working memory를 통하여 기억력검사를 실시하였다. 결과 : nifedipine과 flunarigine 두 약물은 모두 경련 강도를 감소시켰고 flunarizine은 경련 시작 시간도 지연시켜 항경련 작용이 있음을 보였다. 칼슘 통로 봉쇄제는 주로 3일에서 10일 사이에 투여한 경우에 pilocarpine에 의해 기억력이 저하되는 것을 억제하는 것으로 나타났다. 결론 : 이상의 실험 결과에서 칼슘 통로 봉쇄제는 pilocarpine에 의한 경련 억제 작용과 기억력 저하를 억제할 수 있는 작용을 가지고 있음을 확인하였다. The effect of calcium channel blockers, nifedipine and flunarizine, on the pilocarpine-induced seizure and neuronal damage-induced memory deficit in mice was studied. After pretreatment of nifedipine or flunarizine, pilocarpine was administered intraperitoneally. Both drugs attenuated behavioral seizure activity and delayed onset of seizure activity. Memory was tested with working memory version of Morris water mazein 20 days following pilocarpine treatment and showed memory deficit. This deficit in memory was prevented when nifedipine or flunarizine were given during 3 to 6 day or 7 to 10 days after pilocarpine treatment. These results show that calcium channel blockers have anticonvulsant property and depress on pilocarpine-induced memory deficit.

      • 건축공간구성에 있어서 벽난로의 의미와 변천에 관한 연구

        韓受陣,全明鉉 홍익대학교환경개발연구원 1999 환경개발연구논문집 Vol.4 No.-

        The hearth has had a traditional significance, as the heart of the home, or the focus of a community-a source of warmth, for cooking, a point of reference around which life revolves. So we can say that a fire has been concerned with the human life since the primitive ages. The hearth of he primitive ages was transformed into a fireplace and a chimney since the middle ages and such a fireplace, as one of elements of architectural planning, gives characteristic of symbolism and centrality to architectural space. In such aspect, the significance of fireplace is important in composition of architectural space.

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