Clinical Outcome of Modified Cervical Lateral Mass Screw Fixation Technique

Kim, Seong-Hwan,Seo, Won-Deog,Kim, Ki-Hong,Yeo, Hyung-Tae,Choi, Gi-Hwan,Kim, Dae-Hyun The Korean Neurosurgical Society 2012 Journal of Korean neurosurgical society Vol.52 No.2

Objective : The purpose of this study was 1) to analyze clinically-executed cervical lateral mass screw fixation by the Kim's technique as suggested in the previous morphometric and cadaveric study and 2) to examine various complications and bicortical purchase that are important for b-one fusion. Methods : A retrospective study was done on the charts, operative records, radiographs, and clinical follow up of thirty-nine patients. One hundred and seventy-eight lateral mass screws were analyzed. The spinal nerve injury, violation of the facet joint, vertebral artery injury, and the bicortical purchases were examined at each lateral mass. Results : All thirty-nine patients received instrumentations with poly axial screws and rod systems, in which one hundred and seventy-eight screws in total. No vertebral artery injury or nerve root injury were observed. Sixteen facet joint violations were observed (9.0%). Bicortical purchases were achieved on one hundred and fifty-six (87.6%). Bone fusion was achieved in all patients. Conclusion : The advantages of the Kim's technique are that it is performed by using given anatomical structures and that the complication rate is as low as those of other known techniques. The Kim's technique can be performed easily and safely without fluoroscopic assistance for the treatment of many cervical diseases.

T1b 병기의 신세포암에서 수술 후 예후를 예측할 수 있는 임상 및 병리학적 인자에 대한 연구

오승용, 김영원, 윤형윤, 서성필, 이상근, 김원태, 윤석중, 이상철, 김원재, 김용준 충북대학교 의과대학 충북대학교 의학연구소 2014 忠北醫大學術誌 Vol.24 No.1

연구목적: T1병기의 국소신세포암(localized clear-cell renal cell carcinoma)은 근치적신적출술이 나 부분신절제술이 표준치료이며 수술 후 타 병기에 비해 양호한 예후를 보인다. 하지만, 많은 수의 환 자에서 추적관찰 중 재발 및 사망이 발생하는데, 이는 T1b 병기에서 더 높게 보고되고 있다. 본 연구 에서는 국소신세포암 중 T1b 병기의 신세포암에서 표준적 치료 후 환자의 예후에 영향을 주는 임상 및 병리학적 인자에 대하여 알아보고자 하였다. 대상 및 방법: 1999년부터 2011년 까지 5개 기관에서 근치적신적출술이나 부분신제술을 시행 받은 3567명의 국소신세포암 환자들 중 병리학적 병기가 T1b로 확진 된 702명을 대상으로 하였다. 이들 환자가 가지는 임상 및 병리학적 특성 [연령, 성별, 고혈압, 당뇨, 비만도, European Cooperative Oncology Group(ECOG) 수행도, 증상유무, 수술방법, 종양크기, 분화도, 조직학적 형태 등]을 이용 하여 환자의 예후 [무재발생존율(relapse-free survival), 암특이생존율(cancer-specific survival) 및 전체생존율(overall survival)]에 영향을 미치는 인자에 대하여 다양한 방법으로 비교분석 하였다. 결과: 추적 관찰 기간은 34.0개월 (중앙값, 0-152개월)이었으며, 이 기간 중 재발, 사망 및 암특이사 망은 각각 72례 (10.3%), 57례 (8.1%) 및 24례 (3.4%)에서 발생하였다. 단변량 및 다변량 Cox 비례위험회귀분석에서 다양한 인자들이 무재발생존율(당뇨 유무, 종양크기 및 Fuhrman등급), 암특이 생존율(나이, 체질량지수, 당뇨 유무, 종양크기) 및 전체생존율(나이, 체질량지수, ECOG 수행도, 종 양크기)에 영향을 줄 수 있는 독립적 예후인자였다. 결론: 본 연구결과 국소신세포암의 예후를 예측할 수 있는 다양한 임상 및 병리학적 인자를 확인 할 수 있었다. 이러한 위험인자를 가지고 있는 환자는 보다 적극적인 추적관찰을 통하여 재발을 조기에 발 견한다면 이들의 생존율 향상에 많은 기여를 할 수 있을 것으로 생각한다.

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

지렁이를 이용한 슬러지 안정화시 부하율의 영향 및 슬러지 종류별 안정화 가능성 검토

서성철,박종안,이노섭,배형석,이종화,허준무,김준현 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.2

Stabilization of organic sludges using earthworms was conducted in a laboratory to investigate the effect of feed rate on the vermistabilization, and feasibility of vermistabilization of various sludge was also carried out to further wider application of vermistabilization. Sludges used in this study were septic tank sludge, papermill sludge and brewery sludge. Sludge reduction, cast production, earthworm growth rate and cocoon production were monitored periodically to check degree of stabilization. Feed rate of septic tank sludge did not have a notable effect on the sludge reduction and cast production per unit weight or earthworm. There was also no difference in the earthworm growth rate per unit weight of the sludge removed among the different sludge feed rate. The amount of septic tank sludge, papermill sludge and brewery sludge per gram of earthworm per day were 0.06, 0.05, and 0.02g, respectively. The weight of increase of earthworm per unit weight of the sludge removed was 0.18g/g for the septic tank sludge, 0.21g/g for the papermill sludge, and only 0.06g/g for the brewery sludge. It was therefore concluded that brewery sludge was not suitable for vermistabilization mainly due to high organic content to be easily converted organic acid. The concentrations of several heavy metals, volatile solids, total organic carbon and total kjeldahl nitrogen in the cast were generally lower than those in the raw sludges.

전립선암과 전립선비대증 환자에서 혈청 유리 및 총전립선특이항원 측정의 의의

서혁준,박형민,권태균,정성광,김법완,이재태 경북대학교 의학연구소 2000 경북대학교병원의학연구소논문집 Vol.4 No.1

Purpose: This study was peformed to investigate whether the free to total PSA ratio(F/T PSA ratio) offers a better discriminant for the detection of patient with prostatic cancer(CaP) and those with benign prostatic hyperplasia(BPH) than serum total PSA alone. Materials and Methods: From September 1996 to February 1999, free and total PSA levels were measured on frozen sera samples of 154 men with BPH and 46 with CaP using immunoradiometric assay. Results: In all subjects, the mean total PSA was significantly higher in CaP group(72.57±66.58ng/ml) than BPH group(3.12±4.10ng/ml). The mean PSAD was significantly higher in CaP group(1.64± 1.86) than BPH group(0.08±0.01). The mean F/T PSA ratio was significantly lower in CaP group(0.19± 0.07) than BPH group(0.30±0.13). Among 41 subjects whose total PSA were between 4-20ng/ml, the mean PSAD was significantly higher in CaP group(0.37±7.16) than BPH group(0.17± 0.07), but the mean F/T PSA ratio was not significantly different between CaP(0.19± 0.10) and BPH group(0.25±7.13). By comparing the sensitivity and specificity of total PSA alone, PSAD and F/T PSA ratio on receiver operating characterislic (ROC) Cutie in all subiects and subiects with total PSA between 4-20ng/ml, F/T PSA ratio had no superiority than total PSA alone and PSAD for discrimination between CaP and BPH. Conclusions: We suggest that the F/T PSA ratio is not superior to total PSA alone and FSAD in the detection of prostatic cancer, and further evaluation of the usefulness of F/T PSA ratio should be required.

ZnO/ZSM-5상에서 저탄소가의 탄화수소로부터 방향족화의 성능향상

서교택,문세기,김형진 한양대학교 에너지 ·환경기술연구소 1995 에너지·環境技術論文集 Vol.2 No.-

n-헥산의 방향족화 반응에서 HZSM-5에 기계적으로 혼합 첨가된 ZnO의 영향을 연구하였다. n-헥산의 방향족화 반응에 있어서, HZSM-5 자체 만으로도 활성을 나타냄은 물론 HZSM-5에 ZnO가 첨가됨에 따라 활성이 더욱 증대되었다. 이는 ZnO/HZSM-5에서의 방향족화 반응은 이원 기능 과정임을 나타내는 것으로서, 이때 ZnO의 역활은 n-헥산의 탈 수소 반응을 촉진하는 것으로 생각된다. 첨가된 ZnO는 촉매의 산도, 결정성 및 표면적에는 거의 영향을 주지 못하는 반면, 전화율과 방향족 화합물로의 선택도와 같은 촉매 활성에는 많은 변화를 주었다. 그러나, 무엇보다도 중요한 것은 급격한 촉매 활성의 저하를 방지하는 것이라 할 수 있다. The effect of ZnO added to HZSM-5 catalyst by mechanical mixing in aromatization of n-hexane has been studied. It is shown that HZSM-5 alone is active for aromatization of n-hexane and the activity is enhanced by addition of ZnO to the HZSM-5 catalyst. This suggests that the aromatization on the Zno-added catalysts(ZnO/HZSM-5) is a bifunctional process, in which ZnO seems to catalyze the dehydrogenation of n-hexane. Addition of ZnO makes less change in acidity, crystallography and surface area, but leads to significant change in activity in terms of conversion and selectivity toward aromatics. What is more important, however, is that it prevents the rapid decay of catalyst-activity.

Metallo-Pc 촉매에 의한 휘발성 유기화합물의 촉매산화

서성규,김상채,윤형선 여수대학교 1997 論文集 Vol.11 No.2

Catalytic oxidation of methanol as a volatile organic compound(VOC) was studied at atmospheric pressure in a fixed bed flow reactor system over metallo-Pc catalysts. The activity of these catalyst in terms of metal ion, pretreatment gas, reaction temperature, contact time was studied. The experiment was conducted at the reaction temperature of 200~350℃, CH₃OH in air of 2.29 mole%, the contact time of 0.31~3.73gㆍcat-hr/gㆍmol-feed. As a result of study, pretreatment with air and methanol mixture showed the best performance for catalytic activity. The increasing order of catalytic activites for methanol conversion to carbon dioxide and water was as follows : metal free-Pc < Zn-Pc < Fe-Pc < Cu(α)-Pc < Cu(β)-Pc < Co-Pc. The catalytic activity of Co-Pc catalyst was very good at low temperature. And, Co-Pc catalyst had many possibilities as an alternative catalyst for the expensive commercial oxidation catalyst.

매쉬-심 용접 판재의 성형 한계

김형목,허영무,양대호,서대교 기계기술연구소 1999 성균관대학교 논문집 기계기술편 Vol.1 No.1

This paper describes experimental investigation on the forming limit for mash-seam welded sheets. The uniaxial tensile test was conducted to evaluate the mechanical properties of weld bead. Experimental forming limit diagrams were investigated for the different thicknesses and properties of welded sheets.

관상동맥 질환에서 SDF-1α의 농도

김보영,박용규,박형서,노상필,정승현,이유선,이정우,이재환,최시완,정진옥,성인환 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Atherosclerosis is now viewed as an inflammatory disease of the vascular system. Expression of several chemokines, including monocyte chemoattractant protein(MCP)-1, MCP-4, RANTES(regulated on activation normal T-cell expressed and secreted), and interleukin-8(IL-8) are increased in human atherosclerotic plaques compared with normal vessels. They are involved in the pathogenesis of atherosclerosis and plaque rupture by activating and directing leukocytes into the atherosclerotic lesions. However, some are involved in homeostatic functions such as normal leukocyte traffic and growth regulation. SDF-la is a multi-functional cytokine that is involved in myelogenesis, hematopoiesis, angiogenesis and injured gastric mucosal regeneration in the gastric ulcer patient. SDF-la is recently shown to be highly expressed in atherosclerotic plaques and a potent platelet agonist. At least in high concentrations, SDF-la may mediate antiinflammatory and matrix stabilizing effects in unstable angina. Many studies are going on to know the function of SDF-la in coronary artery diseases. I investigated the difference of the plasma level of SDF-la between control group and coronary artery disease group. Total 75 subjects were enrolled. The diagnosis of coronary artery disease was confirmed in all patients by coronary angiography. Control subjects in this study were confirmed normal by coronary angiography. Clinical profile and risk factors were also reviewed. Control subjects in this study were 27 (M=10, F=17). Plasma for the study was collected before the angiography and centrifuged. SDF-la analysis was performed by ELISA. Plasma level of SDF-la is significantly increased in patients with stable angina(n=20) and unstable angina group(n=28) compared with healthy control group(n=27). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases. In this study, plasma level of SDF-la is increased in patients with stable angina and unstable angina groups compared with healthy control group(P<0.05). the risk factors do not influence the plasma level of SDF-la in coronary artery diseases.

利用人員이 不規則한 建築物 計劃에 關한 硏究 : 東海岸 主要都市 宿泊 施設 中心으로 Forcused on the accommodation facillities in Major Cities of East Coast Area

서형수,김효남 三陟大學校 産業科學技術硏究所 2004 産業科學技術硏究論文集 Vol.9 No.1

Young-Dong Area has many different tourist attractions such has beaches, mountains and valleys which require to accommodate different number of people at different times and seasons throughout the year. This fact brings in the complexity of irregular use of buildings, especially for those who run accommodation business. In this study, Sokcho, Yang Yang, Gangneung, Donghae and Samcheok are selected to be observed of the characteristic and the prospect of each city with respect to the tourist accommodation industry by analysing the population statistics, tourist trend, tourist accommodation legislation status and its trend. The purpose of this study is to evaluate the current status of accommodation facilities of East Coast Area in terms of architectural scale planning and to provide basis for the planning of buildings by analysing the scale planning of selected case studies. For case studies, 11 hotels were selected analysis of site/building area, number/area of guest rooms, leisure facilities, and area ratio according to the function were carried out.