신아세포종에 병발된 폐 색전증 1예 보고

박용욱,김형중,서중석 大韓法醫學會 1999 대한법의학회지 Vol.23 No.1

Wilms' tumor is the most common urinary tract neoplasm and one of the most frequent solid abdominal malignant tumors of childhood, usually diagnosed between the ages of 2 and 5 years. Typically, it is manifested as an asymptomatic unilateral or upper abdominal mass. Abdimonal pain after some traumatic incident, fever, anemia, hematuria and hypertension are other patterns of presentation. In a considerable number of these patients, pulmonary metastases are present at the time of primary diagnosis. But, the initial presentation of acute pulmonary tumor emboli without surgical manipulation is very rare. We describe a sudden unexpected infantile death case diagnosed as pulmonary tumor embolism preexisting Wilms' tumor. To our knowledge, this is the initial autopsy presentation of Wilms' tumor with tumor embolism as sudden and unexpected death in Korea.

스티렌 현탁 중합반응에서 폭주반응 해석

박형일,신석주,이헌창,장서일,김태옥 한국산업안전학회 2002 한국안전학회지 Vol.17 No.3

The runaway reaction was analyzed experimently and theoretically at the batch styrene suspension polymerization process. In the experiments, the reaction temperature with time was measured at various experimental conditions. According to the experimental results, the risk of the runaway reaction was increased with increasing the ratio of the monomer(styrene, M) to the dispersion medium(water, W), the concentration of the initiator(BPO), and the monomer mass, respectively. And simulation results showed that the runaway reaction was significantly affected by the reaction rate constant of the propagation and that the phenomena of the runaway reaction occurred at about 70% conversion. Also, we found that the runaway reaction did not occur under the operation condition of below 0.5 for M/W, approximate 3 wt% BPO, and below 75℃ for the cooling temperature.

자연정화공법에 의한 하수처리장에서 최적 여재 선정

서동철,이홍재,조주식,박현건,김형갑,허종수 한국환경농학회 2003 한국환경농학회지 Vol.22 No.1

농어촌 등에서 소규모로 발생하는 하수를 환경친화적이고 높은 하수처리효율을 유지하면서 하수처리장의 장기간 사용을 위한 최적의 여재를 선정하기 위하며 자연정화공법을 이용한 소형하수처리장치를 호기성조 및 혐기성조로 구분하여 시공한 다음, 하수처리량 및 여재 입경별 수처리 효율을 조사하였고, 호기성조와 혐기성조에서 여재 입경별 하수의 투수속도를 조사한 결과는 다음과 같다. 호기성조 처리수 및 방류수중의 pH 및 EC는 여제입경에 따라서 별 차이가 없었고, 용존산소는 호기성조를 동과한 호기성조 처리수의 용존산소는 큰 폭으로 증가하였으나 혐기성조를 통과한 방류수의 용존산소는 호기성조 처리수에 비해 약간 감소하여 여재입경 및 하수처리량에 따라서 별 차이가 없이 약 2.4~5.1 mg/L정도이었다. BOD,000 및 탁도 처리율은 여재 대(4~10 mm)를 사용했을 경우에도 호기성조 처리수에서 BOD 처리율은 약 91%이상, COD 처리율은 73%이상, 탁도 처리율은 83%이상이었으며, 이들 처리율은 여재입경이 작을수록 증가하였고 모든 조건에서 방류수중의 BOD 처리율은 98%이상, COD 처리율은 91%이상, 탁도 처리율은 98%이상이었다. 여재입경별 총 질소 및 총 인 처리율은 여재입경이 작을수록 약간 증가하였고, 모든 조건에서 방류수중의 총 질소 처리율은 약 45~59%, 총 인 처리율은 약 80~96% 정도이었다. 하수 처리율 및 투수속도를 고려해 볼 때 하수처리장 호기성조의 최적입경은 2~4 mm정도 혐기성조의 최적입경은 0.1~4 mm정도가 적절한 젓으로 사료되었다. 따라서 이러한 조건을 자연정화공법을 이용한 하수처리장에 적용하면 높은 하수처리효율을 유지하면서 하수처리장의 공극폐쇄현상이 일어나지 않아 장기간 운전할 수 있을 것으로 판단된다. An investigation was carried out to evaluate the effects of pebble size on the small-scale sewage treatment apparatus by natural purification method that consisted of aerobic and anaerobic plot pH and EC in both plots varied minimally regardless of pebble size. DO in aerobic plot increased as the pebble size decreased. That in the anaerobic plot was slightly less in comparison with that of the aerobic plot, but varied minimally, 2.4~5.1 mg/L regardless of pebble size. Under all experimental conditions, removals of BOD, COD and turbidity in anaerobic plot were more than 98, 91 and respectively. Removals of T-N and T-P increased as pebble size decreased. Under all experimental conditions, removals of T-N and T-P in anaerobic plot were about 45~59 and 80~96%, respectively. Judging from the above results, it should be considered that the optimum pebble size and pebble permeability in both plot was 2~4 mm and 0.1~4 mm, respectively.

중국거주 조선족 여성의 영적 안녕정도가 정신건강에 미치는 영향

정성덕,이종범,김진성,서완석,배대석,박순재,주열,염형욱,김승원,김구묘,안영록,황대홍,표미자,조창열,정태길 영남대학교 의과대학 2004 Yeungnam University Journal of Medicine Vol.21 No.2

자아초월 정신의학이 체계화되면서 영성(spirituality)은 인성의 한 부분이라는 이론이 대두되었는데 이 영성은 정신건강에 큰 영향을 미친다고 했다. 인간의 성향 중 영적 안녕 정도를 파악하여 그 정도가 정신건강 중 허위성 경향, 정신병적 경향 및 불안과 우울 경향 등에 어떠한 영향을 미치는지를 조사하고저 본 연구를 실시하였다. 대상은 중국의 연변 조선족 자치구에 거주하는 여성 400명을 대상으로 하여 한국판 영적 안녕척도를 사용하여 영적 안녕정도를 파악하였다. 영적 안녕척도의 총점과 이 척도의 2개 하위 척도인 종교적 안녕과 실존적 안녕 척도 양자로 평가한 성적이 불안-우울통합척도와 정신분열증 척도 및 허위성 척도로 평가한 성적에 미치는 영향을 검증하기 위하여 상관관계분석 및 회기분석을 실시하였다. 그 결과는 다음과 같다. 1) 영적 안녕척도로 평가한 조선족 여성의 총점은 68.29로 한국의 기독교 여성이 평가한 100.65보다 훨씬 낮은 점수였다. 2) 불안·우울통합척도로 평가한 총점은 44.88로 연변노인이 평가한 점수와 일개지역의 한국농촌주민이 평가한 점수와 비슷한 결과였다. 3) 허위성 척도로 평가한 성적은 평균 74.57로 70점 이상이 86%(344명)이었으나 영적 안녕 성적과 허위성 성적 간에는 유의한 상관이 없었다. 4) 영적 안녕총점은 정신분열증 척도로 평가한 정신병적 경향에 유의한 영향을 미치지 않았으나 종교적 안녕하위척도의 성적은 정신병적 경향을 높여준데 비하여 실존적 안녕하위척도의 성적은 정신병적 경향을 낮게 해주었다. 5) 영적 안녕척도의 총점 및 두 하위척도인종교적 안녕과 실존적 안녕은 불안과 우울에유의한 상관을 보였는데 영적 안녕총점이 높을수록 불안·우울 총점이 다소 낮아지는 경향을 보였다. 6) 종교적 안녕 하위척도와 불안과 우울과의 관계는 종교적 안녕점수가 높을수록 불안과 우울을 각각 다소 유의하게 높여주었으며 이에 비하여 실존적 안녕하위척도와 불안과 우울과의 관계는 실존적 안녕정도가 높을수록 불안 및 우울점수는 유의하게 낮아졌다. 이와 같은 성적을 미루어볼 때 연변에 거주하는 조선족 여성이 평가한 영적 안녕정도는 정신병적 경향과 불안 및 우울에 유의한 상관을 보였으면 이 척도의 하위 척도인 종교적 안녕정도는 정신건강에 부정적인 영향을 미치는 반면 실존적 안녕정도는 정신건강에 긍정적 영향을 미친 결과로 평가되었다. 이러한 결과는 공산주의 사회에서 실존적 안녕은 긍정적인 가치관으로 평가되는 반면 종교적 안녕은 정신건강에 부정적으로 작용한 것을 입증해 주었다고 하겠다. Background: Spirituality has been an important part of Transpersonal Psychology and is believed to have a large effect on the mental health because it has been systematized. The aim of this study was to determine the level of spiritual disposition on human beings along with its effects on one's mental health. Materials and Methods: The study targeted 400 women residing in Youn-Gil city of JiLin Prov., which is a district of the Cho-Sun tribe in China. Their spiritual well-being was studied using the Spiritual Well-being Scale-Korean Version. The spiritual well-being scale consists of 2 sub-scales of religious well-being and existential well-being. The study was evaluated using a lie scale, psychotic trend, and a combined anxiety-depression scale. The results were considered to be factors of one's mental health. The correlation between the spiritual well-being and each tendency was analyzed by regression analysis. Results: The total score of the Cho-Sun tribal women according to the spiritual well-being scale was 68.29 which was much less than the 100.65 of Korean Christian women. There was no significant correlation between the spiritual well-being and the Lie trend. However, it was found that 86%(344) of Cho-Sun tribal women scored above 70 in the Lie trend with a mean score of 74.57 which is higher than normal populations. Regarding the correlation between the spiritual well-being and psychotic trend, the psychotic trend became significantly higher when the religious well-being was at a high level. On the other hand, the psychotic trend became significantly lower when the existential well-being was at a high level. Regarding the correlation between the spiritual well-being and anxiety, the anxiety was significantly higher when the religious well-being was at a high level. However, the anxiety level was significantly low when the existential well-being was at a high level. Regarding the correlation between the spiritual well-being and depression, the depression level was somewhat significantly high when the religious well-being was at a high level. However, the depression level was significantly low when the existential well-being was at a high level. Conclusion: This study evaluated the effects of spiritual well-being on a person's mental health among Cho-Sun tribal women in Youn-Gil city of JiLIn Prov., P.R. of China. The results found that the religious well-being, which is a sub-scale of spiritual well-being, had negative effects while the existential well-being had positive effects on the mental health. These results proved that a person's religious disposition had negative effects on their mental health in a communitarian society.

Poster Session 2 : A novel hypopigmenting molecule; terrein

( Seo Hyoung Park ),( Dong Seok Kim ),( Won Gon Kim ),( In Ja Ryoo ),( Dong Hun Lee ),( Chang Hun Huh ),( Sang Woong Youn ),( Ick Dong Yoo ),( Kyoung Chan Park ) 한국생화학분자생물학회 (구 한국생화학회) 2005 생화학분자생물학회 춘계학술발표논문집 Vol.2005 No.-

A New Early-Heading and High-Yielding Forage Oat Cultivar, “Highspeed”

Hyoung Ho Park,Hwa Young Heo,Jung Gon Kim,Ki Hun Park,Jae Seong Choi,Young Up Kwon,Jung Hyun Nam,Jung Jun Lee,Choon Ki Lee,In Mo Ryu,Seo Bong Ko,Kwang Yong Jung,Seong Hee Lee 한국육종학회 2006 한국육종학회지 Vol.38 No.4

A new oat (Avena sativa L.) cultivar, “Highspeed” was developed by Honam Agricultural Research Institute (HARI) in 2005. It was released because of its earliness, high forage yield potential, and good adaptability for late summer sowing. “Highspeed” was selected from the mutants of “Olgwiri” irradiated by 250 Gray of γ-ray emitted from ⁶⁰Co in 1998. Subsequent generations were handled in bulk breeding method and M3 was handled in pedigree breeding method. The line, “OlgwiriM250-B- 268”, was selected for earliness and good agronomic characteristics and designated as “Gwiri48” and finally named as ‘Highspeed’. Over 3 years of regional yield trial, “Highspeed” averaged 6.3 MT/ha in forage production as dry matter when sowed in mid August and harvested in early November. It was superior to the check variety, “Swan” with an 34% of yield-increase. Heading date was October 23 which was 6 days earlier than that of “Swan”. “Highspeed” would be recommended as a summer-sowing oat for producing forage just before winter in Korea.

NecroX-5 prevents breast cancer metastasis by AKT inhibition via reducing intracellular calcium levels

Park, Jin-Hee,Kim, Hyoung Kyu,Jung, Hana,Kim, Ki Hyang,Kang, Mi Seon,Hong, Jun Hyuk,Yu, Byeng Chul,Park, Sungjae,Seo, Su-Kil,Choi, Il Whan,Kim, Soon Ha,Kim, Nari,Han, Jin,Park, Sae Gwang Spandidos Publications 2017 International journal of oncology Vol.50 No.1

<P>A major goal of breast cancer research is to prevent the molecular events that lead to tumour metastasis. It is well-established that both cytoplasmic and mitochondrial reactive oxygen species (ROS) play important roles in cell migration and metastasis. Accordingly, this study examined the molecular mechanisms of the anti-metastatic effects of NecroX-5, a mitochondrial ROS scavenger. NecroX-5 inhibited lung cancer metastasis by ameliorating migration in a mouse model. In human cancer cells, the inhibition of migration by NecroX-5 is cell type-dependent. We observed that the effect of NecroX-5 correlated with a reduction in mitochondrial ROS, but mitochondrial ROS reduction by MitoQ did not inhibit cell migration. NecroX-5 decreased intracellular calcium concentration by blocking Ca2+ influx, which mediated the inhibition of cell migration, AKT down regulation and the reduction of mitochondrial ROS levels. However, the reduction of mitochondrial ROS was not associated with supressed migration and AKT downregulation. Our study demonstrates the potential of NecroX-5 as an inhibitor of breast cancer metastasis.</P>

A New Early-Heading and High-Yielding Forage Oat Cultivar, “Darkhorse”

Hyoung Ho Park,Hwa Young Heo,Jung Gon Kim,Ki Hun Park,Jae Seong Choi,Young Up Kwon,Jung Hyun Nam,Jung Jun Lee,Choon Ki Lee,In Mo Ryu,Seo Bong Ko,Kwang Yong Jung,Seong Hee Lee 한국육종학회 2006 한국육종학회지 Vol.38 No.4

A new oat (Avena sativa L.) cultivar ‘Darkhorse’ was developed by Honam Agricultural Research Institute (HARI) in 2005. It was released because of its earliness, high forage yield potential and adaptability for late summer sowing. It was developed from the artificial cross between ‘SPRINTER’ and ‘73625’ made in 1995. Subsequent generations were handled in pedigree breeding method. The line, ‘SO95036-B-86-8-3-2’, was selected for earliness and good agronomic characteristics and designated as ‘Gwiri43’ and finally named as ‘Darkhose’. Over 3 years of regional yield trials, ‘Darkhorse’ averaged 6.1 MT/ha in forage production as dry matter when sowed in mid August and harvested in early November. It was superior to the check variety, ‘Swan’, with an 31% of yield increase. Heading date was October 25 which was 4 days earlier than that of ‘Swan’. ‘Darkhorse’ would be recommend as a summer-sowing oat for producing forage just before winter in Korea.

Poster Session 2 : Oral Presentation ; Molecular Medicine and Application : A novel hypopigmenting molecule; terrein

( Seo Hyoung Park ),( Dong Seok Kim ),( Won Gon Kim ),( In Ja Ryoo ),( Dong Hun Lee ),( Chang Hun Huh ),( Sang Woong Youn ),( Ick Dong Yoo ),( Kyoung Chan Park ) 한국생화학분자생물학회 (구 한국생화학회) 2005 62회 KSBMB Annual Meeting in 2005 Vol.- No.-

Development of a Mathematics, Science, and Technology Education Integrated Program for an Airplane

Park, Hyoung-Seo 한국실과교육연구학회 2006 實科敎育硏究 Vol.12 No.2

이 연구는 초등학생이 비행기 만들기 체험 활동을 중심으로 수학적.과학적 기술적 소양을 함양하기 위한 통합교과교육 프로그램을 개발하여 우리나라 핵생들의 수학.과학.기술교육에 대한 정의적 태도 즉 학습 동기, 호기심. 흥미를 고양시키는 데 있다. 이 연구는 개발 연구로서 설문 조사와 예비/현장 시험을 병행하여 이루어졌다. 그리고 개발 절차는 준비 단계, 개발 단계, 개선 단계의 과정을 거쳤다. 준비 단계에서는 문헌 연구를 통하여 교과ㆍ학습자ㆍ사회의 요구 분석을 하였다. 개발 단계에서는 초등학교 수학, 과학, 실과, 재량활동 수업에서 활용하기 위한 설계 개요, 교사용 지침서, 학생의 활동 자료를 개발하였다. 설계 개요는 상황, 문제. 설계 제한점. 체험 학습, 문서화 목록으로 구성하였다. 교사용 지침서는 모범적 해결책, 프로그램의 목표, 응용 목록, 수업 계열, 활동의 단계, 학생 활동의 계열, 도입, 용어의 해석, 자료의 목록을 개발하였다. 학생 활동 자료는 학생들의 활동 지침서로서 수학ㆍ과학ㆍ기술교육의 내용을 비행기 만들기 체험활동 중심으로 세 교과의 내용을 탈학문적으로 통합하였다. 개선 단계에서는 비행기 만들기 체험 활동 프로그램을 초등학생을 대상으로 예비시험을 실시하고 그 결과에 따라서 수정하고 보완하였다.