절수에 의한 mongolian gerbil의 체중 변화에 관한 연구

이경열,송치원,김무강,조성환,류시윤,김상근,박배근 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

Recently, the mongolian gerbils have been used in neurology and the study of water metabolism because of their easy onset of epileptic seizure and typical resistance to water deprivation. The sebaceous glands which are under the control of the gonadal hrmones are differently developed from the other laboratory animals. However the physiological data on the changes of body weight following water deprivation in mongolian gerbils is not available until now. In order to investigate the effect of the water deprivation on the body weight, the animals were deprived of water for 15 days. The body weights were measured daily by the torsion balance. The mean, the standard deviation, the standard error and the coefficient of variance of the body weights were calculated. The correlation was examined. The potential regression equation was y = 61.5458 - 2.0533 * x + 0.0487 * x^2. The regression coefficient was 0.993. The results obtained were as follows : 1. The body weights of the mongolian gerbils were continuously decrased from the 1st day to the 15th day after the water deprivation. 2. The mean body weight on the water deprivation was 63.0±7.00g and that at the 15th day was 41.4 ± 5.42g. 3. The coefficients of the variance showed the highest (13.09) at the 15th day and the lowest (10.10) at the 10th day. the coefficients of the variance kept decreasing until the 10th day and thereafter gradually increased until the 15th day. 4. The changing rate of the body weight kept continuously decreasing from the 1st day to the 15th day showing the daily loss of 1.0 - 3.3%. 5.The deviations (M - QBW) between the measured values (m) and the theorical values (QBW) using the regression equation showed the highest (1.494) at the 1st day and the lowest (0.053) at the 13th day. 6. The sum of the devitions was 0.179 and that of the deviation square was 1.15. The sum of the deviation rates between the mesaured body weights and the theorical ones was 0.484. 7. The daily body weight loss showed the highest at the 1st day by 2.053g and the lowest at the 15th day by 0.591g. 8. The specific body weight changing rates which were the rate of the body weight changing velocity to the changed body weight were decreased from 0.033% at the 1st day to 0.014% at the 15th day.

n-CdS_(0.46)Se_(0.54)/p-Cu_92-x)S_(0.46)Se_(0.54) 이종접합 태양전지의 제작과 그 특성에 관한 연구

유상하,최승평,이상열,홍광준,서상석,김혜숙,전승룡,윤은희,문종대,신영진,정태수,신현길,김택성,유기수 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.16 No.-

승화방법에 의해 CdS_0.46Se_0.54 단결정을 성장하여 결정구조를 조사하고, Van der Pauw 방법으로 Hall effect를 측정하여 carrier density의 온도 의존성과 mobility의 온도 의존성을 조사하였다. 성장된 CdS_0.46Se_0.54 단결정을 치환반응하여 n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 이종접합 태양전지를 제작하였다. Spectral response, 전류-전압특성 및 전력변환 효율을 조사하여 그 결과로부터 개방전압은 0.48V, 단락 전류 밀도는 21mA/㎠, fill factor와 전력변환효율은 각각 0.75와 9.5%를 얻었다. CdS_0.46Se_0.54 single crystal was grown by a sublimation method. The crystal structure and the temperature dependence of carrier density and mobility of CdS_0.46Se_0.54 single crystal were studied. Heterojunction solar cells on n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 were fabricated by the substitution reaction. The spectral response, the J-U characteristics and the conversion efficiency of the n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 heterojunction solar cells were studied. The open-cricuit voltage, short-circuit density, fill factor and conversion efficiency of n-CdS_0.46Se_0.54/p-Cu_2-xS_0.46Se_0.54 heterojunction solar cells under 80mW/㎠ illumination were found to be 0.48V, 21mA/㎠, 0.75 and 9.5%, respectively.

C.V.D. 방법에 의한 Cd_0.78Zn_0.22 S박막 성장과 광전기적 특성연구

유상하,이상렬,홍광준,서상석,김혜숙,전승룡,윤은희,문종대 조선대학교 기초과학연구소 1993 自然科學硏究 Vol.16 No.1

We had grown Cd_0.78Zn_0.22S polycrystal thin films on slide substrate using chemical vapour deposition(CVD) method. We measured X-ray diffraction patterns in order to study Cd_0.78Zn_0.22S polycrystal structure. We studied its band gap using transmission curves and photocurrent and also analyzed photoluminescence using configurational coordinate model. We measured Hall effect·on this sample by Van der Pauw method and studied on carrier density and mobility depending on temperature.

KAL기 추락에 의한 대량재해의 개인식별

강신몽,이원태,고영창,최상규,김윤희,이홍석,서재관,윤중진,이혜경,최득린,김종열,윤창육,변명식,이장홍 大韓法醫學會 1991 대한법의학회지 Vol.15 No.2

Individual identification is an important part in medicolegal field especially in mass disaster. At July, 27, 1989, KAL KE-803 was crashed on landing at Tripoli International Airport, Liba. The plane was caught in fire and sixty eight Koreans were sacrified. The majority of victims were severely charred and injured. The authors examed all dead bodies and successfully identified all the cases through visual, anthropological, odontological, radiological and pathological methods including fingerprint and blood typing.

[P397] A case of basal cell carcinoma arising from nevus sebaceus

( Sang Youl Yun ),( Min Woo Park ),( Moo Kyu Suh ),( Jung Ran Kim ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Nevus sebaceous is a benign hamartoma with epidermal, follicular, and apocrine elements. Nevus sebaceous accompanied by various secondary tumors after adolescent. Most common secondary tumors developed within the nevus sebaceous are syringocystadenoma papilliferum, trichoblastoma, and trichilemmoma. The development of basal cell carcinoma is seen in less than 1% of lesions. We report a case of basal cell carcinoma arising from nevus sebaceous in 67-year-old man. The patient presented with asymptomatic yellow brownish colored verrucous plaque since birth with brownish nodule for several years on the left temple. Skin biopsy specimen from yellow brownish plaque showed hyperkeratosis, papillomatosis, sebaceous hyperplasia on the papillary dermis. Specimen from brownish nodule showed basaloid cells that have attachment to the epidermis extend to the papillary dermis, and peripheral cell layer of the tumor masses shows a palisade arrangement of the nuclei. Because of these histologic findings, basal cell carcinoma arising from nevus sebaceous was diagnosed. Then we treated with surgical excision.

Human immunodeficiency virus infection manifested as the presenting condyloma acuminatum

( Sang Youl Yun ),( Min Woo Park ),( Moo Kyu Suh ),( Jung Ran Kim ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Condyloma acuminatum is common sexually transmitted disorder caused by human papillomaviruses. It consists of epidermal and dermal papules or nodules on the perineum, genitalia, crural folds, and anus. It varies in size and can form large, exophytic, cauliflower-like masses, especially in the moist environment of the perineum. There have been few studies about relationship between condyloma acuminatum and HIV infection. We report a case of human immunodeficiency virus infection manifested as the presenting condyloma acuminatum. A 55-year-old heterosexual healthy man presenting with multiple grouped brownish verrucous papules on the perianal area. Histologic examination showed hyperkeratosis, acanthosis and papillomatosis in the epidermis. In the thickened epidermis, there were several keratinocyte with vacuolated cytoplasm. Anti-HIV antibodies were detected in electrochemiluminescence immunoassay(ECLIA) and confirmed by Western blot assay. Therefore, he was diagnosed as condyloma acuminatum with HIV infection. For further treatment of both HIV infection and condyloma acuminatum, we transfered the patient to hospital specialized in HIV infection.

Toxic epidermal necrolysis associated with methazolamide treatment

( Sang Youl Yun ),( Jun Gyu Song ),( Moo Kyu Suh ),( Tae Jung Jang ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Toxic epidermal necrolysis (TEN) is rare life-threatening disease, characterized by extensive necrosis and detachment of the epidermis. The pathophysiology of TEN is still unclear. But drugs are the most important etiologic factors. More than 100 different drugs have been implicated. High risk dugs are antibacterial sulfonamides, aromatic anticonvulsants, allopurinol, oxicam non steroidal anti-inflammatory drugs, lamotrigine and nevirapine. This disease also has been often associated with methazolamide which is a sulfonamide derivative and carbonic anhydrase inhibitor used for lowering of intraocular pressure in glucoma. We report a case of TEN induced by methazolamide on the 63-year-old glaucomatous male patient who presented with multiple, pricking erythematous macules, patches with bullae on the face, trunk, both extremities involving erosive oral mucosa. He received IVIG and corticosteroid treatment, given initially as 5g IVIG daily for 3 days and intravenous 250mg methylprednisolone daily and later changed to oral methylprednisolone. New epithelialization appeared within 2 weeks, and the lesions gradually resolved. The patient was discharged with normal oral feeding 6 weeks after admission. He has remained in good health without recurrence of symptoms during 7 months of follow-up. Methazolamide should be prescribed with caution in Korean glucomatous patients.

A clinical and etiological analysis of subcutaneous mycoses

( Sang Youl Yun ),( Moo Kyu Suh ),( Gyoung Yim Ha ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: There have been many studies about sporotrichosis in Korean dermatological literature. However, a few studies have reported on subcutaneous mycoses except sporotrichosis. Objectives: The purpose of this study was to investigate the clinical and etiological analysis of subcutaneous mycoses. Methods: In the 20-year-period 1996-2015, we reviewed seventeen patients with subcutaneous mycoses were evaluated in regard to the age, gender, occupation, trauma history and associated diseases. Results: Age distribution was most prevalent in sixties(35.2%). The male to female ratio was 1:1.8. Most patients were agricultural workers(52.8%), although preceding trauma was noted in seven patients(41.2%). The most common skin lesion was erythematous plaque (58.7%), followed by abscess, ulcer, papule and nodule. The most frequently involved area was upper extremities(58.8%), followed by face, lower extremities. Hyalohyphomycosis was the most common infection in 6 cases (35.2%), followed by sporotrichosis 5 cases(29.4%), chromoblastomycosis 4 cases(23.5%), phaeohyphomycosis 2 cases(11.8%). Sporothrix species was most common etiological agent(29.4%), followed by Fonsecaea species(23.5%), Scedosporium species(17.6%), Exophiala species(11.8%), Fusarium species, Paecilomyces species, and Cephalotheca species Conclusion: Because of the increase in subcutaneous mycoses except sporotrichosis, we suggest the need of a careful mycological examination in patients with subcutaneous mycoses.

[P394] A case of sebaceoma of the left preauricular area

( Sang Youl Yun ),( Jun Suk Hong ),( Moo Kyu Suh ),( Jong Im Lee ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Sebaceous epithelioma and sebaceoma have been used to describe lesions consisting of primarily germinative seboblasts. Others have used the term sebaceoma to describe benign sebaceous proliferations deep in the dermis as opposed to the more superficial sebaceous adenoma. It appears as a yellowish papule, nodule, or plaque on the scalp and face, on which there are abundant sebaceous glands. But, sebaceous neoplsms of the ear and external ear canal are very rare. Only one case of sebaceoma of the earlobe have been reported in Korean literature. We report a case of sebaceoma occurring in 65-year-old woman. The patient presented with a solitary asymptomatic 4.0×2.0cm sized verrucous yellowish colored plaque with ulcer on the left preauricular area for 20years ago. Skin biopsy specimen showed well-circumscribed lesion composed of undifferentiated basaloid cells and mature sebaceous cells in relatively preserved lobulated architectures. On immunohistochemical study, the tumor cells were positive for CK7, Ki-67, D2-40. Because of these histologic findings, sebaceoma was diagnosed. She treated with surgical excision.

[P255] A case of toenail onychomycosis due to Aspergillus terreus

( Sang Youl Yun ),( Min Woo Park ),( Moo Kyu Suh ),( Gyoung Yim Ha ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Onychomycosis is caused by dermatophytes usually, but some species of nondermatophytic molds and yeasts are also associated with invasion of nails. Aspergillus(A.) terreus is a nondermatophytic mold which is opportunistic filamentous fungus in all environments. We report a case of onychomycosis caused by A. terreus in a 60-year-old male. The patient showed Brownish yellow discoloration with hyperkeratotic change on the distal and lateral portion of both toenails. Direct microscopic examination of scraping on the potassium hydroxide preparation revealed septate hyphae and repeated cultures on Sabouraud’s dextrose agar showed the velvety, cinnamon brown colonies. Biseriate and compactly columnar phialides that cover upper vesicle with conidial structure were shown in the slide culture. The DNA sequence of internal transcribed spacer(ITS) region of clinical sample was 99% match to that of A. terreus strain ATCC 20542 (GenBank accession number GU256759.1). We confirmed A. terreus by KOH mount, colony, light microscopic morphology and DNA sequence analysis. The patient was treated with 200mg oral itraconazole daily and topical 5% amorolfine nail lacquer for 3 months.