정신과 외래환자의 약물치료 반응과 심박동 변이의 변화 양상

이상규,이홍석,김인주,김형태,김도훈,손봉기 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.6

Objectives : The purpose of this study was to investigate the change of heart rate variability after antidepressant treatment in depressed or anxious patients. We tried to find the usefulness of heart rate variability as a predictive marker of response to pharmacological treatments in the psychiatric field. Methods : Forty-seven patients with major depression, anxiety disorder, and somatoform disorder were treated over 4 weeks with antidepressants and were then classified as responders or nonresponders according to Hamilton depression scales or CGI scores. The HRV variables were measured and compared among the responders/nonresponders and the matched normal control. Results : The responders group exhibited low heart rate, low PSI, high SDNN, RMSSD, HRV index, NN50, pNN50, LNTP, LNLF, and LNHF compared with the nonresponders after 4 weeks antidepressant treatment. However, no significant differencein HRV vanables was observed between the responders group after treatment and the nonnal control group and the responsegroup after treatment. Conclusion : These results indicate that HRV variables would are normalized after successful antidepressant treatment and it that HRV has some possible uses as a predicting marker of antidepressant response.

구리의 전기석출시 젤라틴이 물성에 미치는 영향

신석재,강현춘,안형환,강안수,김용렬,한성만,이한섭 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

In the electrodeposition of copper foil for preparing printed circuit boards, a little amount of gelatin as a addition agent has been used for the better characteristics of a coat of electroplating. Gelatin modifies the physical properties such as mechanical strength, matte-side roughness, ultimate tensile strength(U.T.S), and elongation of copper foil, furthermore gelatin have influence on the structure of electrodeposits and the cathode polarization. The electrolyte used was of a composition; CuSO₄·5H₂O 300g/ℓ, H₂SO₄ 100g/ℓ, NaCl 10 ppm as a brightner, and was gelatin 0-7 ppm as a addition agent. Current density was 50 A/dm², and the temperature of electrolytic bath was 50 to 52 ℃. Experiments showed that the optimum gelatin concentration was 5 ppm with the consideration of the numbers of electrodeposited nuclei. And the nuclei numbers was sharply increased under 5 ppm, but was almostly constant above 5ppm. Average matte-side roughness by Surfcorder was gradually increased with the increasing gelatine concentration up to 2 ppm, and maximum roughness was observed at 2ppm. The roughness showed gradual decrease within the concentration range of 2 to 4 ppm, and was almost constant above 4ppm . Within the gelatine concentration range of 0 to 7 ppm, as the concentration increased, UTS was increased and elongation was decreased logarithmically. Also, in comparison between UTS and elongation, gelatin was identified as an addition agent acting inversely.

공업고등학교 전기학과의 전기수학교육에 관한 연구

이상석,신용철,김민회,박찬규,이재용 영남이공대학 2004 論文集 Vol.33 No.-

This research is that concern in electrical mathematics education of Technical high school Department of Electricity in the 7th educational curriculum. In the 7th educational curriculum, indicated problem about mathematics education of Technical high school Department of Electricity and examine major subject, contents of mathematics that use in major subject and analyzed contents of mathematics that must supplement. With this analysis, established necessary electrical mathematics contents for major subject studying of Technical high school Department of Electricity.

공업고등학교 전기과과 전문대학 전기과의 교과목 연계를 위한 교과내용 개선연구

이상석,김민회,박찬규,이재용 영남이공대학 2003 論文集 Vol.32 No.-

Most of our college students in the department of electricity are from technical high school. Thinking that a lot of those high school students are going to try out for our college, we have come up to the idea to have stable student resources and to keep the resources that we should have researched on this matter. As first solution, considering scholastic ability for students, our college should help them to have easier understandings on their major subject studies. To let them have better condition of studying, we have analyzed 6th and 7th high school curriculum for electric text and studied how much influence 7th the curriculums have on major subject studies. Also we have looked through high school mathematics and basic electric texts under 7th the curriculums. After examining these analysis, we have had some suggestions about the ways to provide easier understandings and reorganized contents in a major basic text of college.

방사선으로 照射된 Polyethylene의 光電氣傳導

韓相勳,金永銓,조성석 충남대학교 자연과학연구소 1984 忠南科學硏究誌 Vol.11 No.1

Electronic conduction in various polymeric insulating material was investigated. Specially photo-current was observed in low density and 30 μ thick polyethylene when the sample was exposed by low-intensity white light from a tungsten lamp. A large photo-current was observed for the pre-irradiated sample by high dosage γ-ray. Photo-current was measured for many factors, wave length, voltage, temperature. Photo-current is fairly sensitive to photons with a certin range of energy (about 0.83eV), which might support that charge carriers are optically released from trap centers, it has approximately the same activation energy as the dark current. A tentative energy diagram for irradiated polyethylene is proposed on the assumption of band model. It includes two kinds of shallow trap and deep trap which are considered to play an important role in electrical conduction of polymeric insulator.

공간적 영상 분할에서 과분할 방지를 위한 개선된 분수령 알고리즘

윤영우,김상곤,전대성,장주석 영남대학교 공업기술연구소 2001 工業技術硏究所論文集 Vol.29 No.1

In this paper, we propose the improved watershed algorithm that resolves the oversegmentation problem shown in the previous watershed algorithm and its modifications when the spatial video segmentation is performed. The principal idea of the proposed algorithm is merging the shallow catchment basin whose depth is less than a given threshold into the deeper one during flooding step. In the flooding process, the growth of the existing catchment basins and the extraction of newly flooded ones are accomplished. We present the experimental results using several MPEG test sequences in the last part of the paper. As a consequence, the proposed algorithm shows good segmentation results according to the thresholds applied by adding very small amount of calculations.

BMS 수리모형하에서 시스템의 수리효과 및 고장강도함수의 모수추정

윤원영,정석주,정일한,김종운,정상욱 한국경영과학회 2000 韓國經營科學會誌 Vol.25 No.4

Estimation problems of parameters of the failure process and the repair effect in repairable systems are considered. We propose estimation procedures in repairable systems without preventive maintenances. The fallure process is modeled by a proportional age reduction model (Brown. Mahoney, Sivazlian [5]) which is able to consider both aging and repair effects. Maximum likelihood method is used to estimate the repair effect and parameters of intensity function simultaneously. Simulations are performed to evaluate the accuracy of estimators. A numerical example is also presented.

풍력발전기 축소 구조 모델의 진동특성 연구

박무열,은성용,김석현 江原大學校 産業技術硏究所 2004 産業技術硏究 Vol.24 No.B

A reduced structure model of a wind turbine generator is designed and manufactured. Mode data are obtained by modal testing and analytical method. Vibration response is measured and investigated under various speed condition by using a waterfall plot. Possibility of severe resonance is observed and the mechanism is explained by using the mode data. Simplified theoretical model gives the 1st resonance frequency of wind turbine structure model. The theoretical model can be applied in the design stage of the wind turbine structure to avoid the severe resonance problem.

심장 이식 환자에서 발생한 Cryptococcus neoformans에 의한 뇌막염 2예 : The report of two cases

박재형,이윤정,강수진,정영훈,장진석,정준원,최상호,김순종,김양수,김재중 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.3

최근 장기 이식과 관련된 면역억제제의 사용 빈도의 증가 및 후천성면역결핍증 환자의 증가 등으로 인해 기회감염이 증가되고 있으며, C. neoformans에 의한 감염도 증가되고 있다. 저자들은 심장이식 후 6개월이상 지난 환자에서 발생한 크립토코쿠스 뇌막염 2예를 경험하였는데, 한 예의 경우는 거대세포 바이러스 감염과 함께 C. neoformans의 전신적 파급성 감염의 형태로 나타났었고, 폐에 A. fermigatus에 의한 감염이 같이 병발된 경우였다. 이들은 모두 경미한 증상만을 호소하였고, 뇌척수액 검사를 통해 진단받았으며 liposomal amphotericin B와 경구용 fluconazole을 사용하여 완치되었기에 문헌고찰과 함께 보고하는 바이다. Cryptococcal meningitis is a subacute or chronic mycotic infection caused by Cryptococcus neoformans and it is a second most common central nervous system (CNS) infection in organ transplant patients. The recent rise in incidence of the disease can be attributable to the wide use of immunosuppressive agents in organ transplant patients, the advent of acquired immunodeficiency syndrome (AIDS) patients and increased use of chemotherapeutic agents. We report two cases of cryptococcal meningitis after cardiac transplantation. Their symptoms were not typical and neurologic examination was nonfocal. One patient had disseminated cryptococcal infection and invasive pulmonary aspergillosis, it might be assodated with cytomegalovirus infection. They were diagnosed by cryptococcus latex agglutinin test and culture study with cerebrospinal fluid and treated with liposomal amphotericin B and oral fluconazole without any neurologic defects.

Scopoletin Production Related to Induced Resistance of Tobacco Plants Against Tobacco mosaic virus

Kim, Young-Ho,Choi, Do-Il,Yeo, Woon-Hyung,Kim, Young-Sook,Chae, Soon-Yong,Park, Eun-Kyung,Kim, Sang-Seock The Korean Society of Plant Pathology 2000 Plant Pathology Journal Vol.16 No.5

A fluorescent material was accumulated in inoculated leaves showing necrotic local lesions of tobacco plants with N gene, Nicotiana tabacum cvs. Xanthi-nc NN, Samsun NN, Burley 21 and KF 114, and N. glutinosa, and Datura stramonium at the early growth stages by the inoculation of Tobacco mosaic virus (TMV). It was identified as a coumarin phytoalexin, scopoletin. Although the material was most prominently produced in TMV-inoculated tobacco leaves with local necrotic lesions, its accumulation was also noted in uninoculated leaves of TMV-inoculated plants. Its accumulation was somewhat greater in high resistance-induced leaves than low resistance-induced and intact leaves. Scopoletin treatment induced the expression of a pathogenesis-related protein, PR-1, prominently at the concentration of 500 or 1000 ${\mu}$g/ml. This suggests that scopoletin is a phytoalexin abundantly accumulating in N gene-containing resistant plants in response to TMV infection, and may be related to hypersensitive responses (HR) and systemic acquired resistance (SAR) in the resistant tobacco plants.