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LC,Acute : PO-29 ; Effect of balloon-occluded retrograde transvenous obliteration on liver function
( Kwang Duck Ryu ),( Jeong Heo ),( Hyun Young Woo ),( Dong Uk Kim ),( Gwang Ha Kim ),( Geun Am Song ),( Mong Cho ),( Ki Tae Yoon ),( Chang Won Kim ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background: Balloon-occluded retrograde transvenous obliteration (BRTO) is one of the therapeutic methods for the treatments of gastric varices with splenorenal shunt. BRTO is a very useful treatment in terms of bleeding control. However there are few reports that evaluated about influence of liver function after BRTO procedures. Methods: From August 2004 to September 2011 at Pusan National University Hospital, we retrospectively reviewed the medical records of patients with liver cirrhosis, who were performed the BRTO procedures to treat their gastric varices or gastric variceal bleeding. The improvement of liver function was defined reduction of Child-Pugh (CP) score. CP class checked at before BRTO, 3month and 6month after. Results: Total 81 patients were analyzed. At baseline, 40.7% was CP class A, 53.1% CP class B, 4.9% CP class C. CP class data at 3 months was available in 57 patients and at 6 months in 42 patients. At 3 month, CP class was improved in 17.3% (14/81), not changed in 49.4% (40/81) and worsened in 3.7% (3/81). At 6 month, CP class was improved in 16.0% (13/81), not changed in 27.2% (22/81) and worsened in 6.2% (5/81). In multivate analysis, independent predictor associated with improvement of liver dysfunction was only CP class at baseline (p=0.005). Patient with improvement at 3 months was CP class A in 0, CP class B in 13 and CP class C in 1. Patient with improvement at 6 months was CP class A in 1, CP class in 11 and CP class C in 1. Rebleeding after BRTO occurred in 6 patients and all of them had baseline CP class B (p=0.044) Conclusion: Liver dysfunction was not significantly worsened in cases of liver cirrhosis after BRTO procedures. Liver function might be improved in some patients after BRTO.
( Kwang Duck Ryu ),( Gwang Ha Kim ),( Seong Oh Park ),( Kwang Jae Lee ),( Jung Youn Moon ),( Hye Kyung Jeon ),( Dong Hoon Baek ),( Bong Eun Lee ),( Geun Am Song ) 대한소화기학회 2014 Gut and Liver Vol.8 No.4
Background/Aims: Helicobacter pylori eradication therapy has been used as a first-line treatment for H. pylori-positive gastric mucosa-associated lymphoid tissue (MALT) lymphoma. However, the management strategy for H. pylori-negative MALT lymphoma remains controversial. Therefore, the aim of this study was to examine the success rate of each treatment option for H. pylori-positive and H. pylori-negative gastric MALT lymphomas. Methods: In total, 57 patients with gastric MALT lymphoma diagnosed between December 2000 and June 2012 were enrolled in the study. The treatment responses were compared between H. pylori-positive and H. pylori-negative gastric MALT lymphomas. Results: Of the 57 patients, 43 (75%) had H. pylori infection. Forty-eight patients received H. pylori eradication as a first-line treatment, and complete remission was achieved in 31 of the 39 patients (80%) with H. pylori-positive MALT lymphoma and in five (56%) of the nine patients with H. pylori-negative MALT lymphoma; no significant difference was observed between the groups (p=0.135). The other treatment modalities, including radiation therapy, chemotherapy, and surgery, were effective irrespective of H. pylori infection status, with no significant difference in the treatment response between H. pylori-positive and H. pylori-negative MALT lymphomas. Conclusions: H. pylori eradication therapy may be considered as a first-line treatment regardless of H. pylori infection status. (Gut Liver 2014;8:408-414)
LC, Acute : PO-29 ; Effect of balloon-occluded retrograde transvenous obliteration on liver function
( Kwang Duck Ryu ),( Jeong Heo ),( Hyun Young Woo ),( Dong Uk Kim ),( Gwang Ha Kim ),( Geun Am Song ),( Mong Cho ),( Ki Tae Yoon ),( Chang Won Kim ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Background: Balloon-occluded retrograde transvenous obliteration (BRTO) is one of the therapeutic methods for the treatments of gastric varices with splenorenal shunt. BRTO is a very useful treatment in terms of bleeding control. However there are few reports that evaluated about influence of liver function after BRTO procedures. Methods: From August 2004 to September 2011 at Pusan National University Hospital, we retrospectively reviewed the medical records of patients with liver cirrhosis, who were performed the BRTO procedures to treat their gastric varices or gastric variceal bleeding. The improvement of liver function was defined reduction of Child-Pugh (CP) score. CP class checked at before BRTO, 3month and 6month after. Results: Total 81 patients were analyzed. At baseline, 40.7% was CP class A, 53.1% CP class B, 4.9% CP class C. CP class data at 3 months was available in 57 patients and at 6 months in 42 patients. At 3 month, CP class was improved in 17.3% (14/81), not changed in 49.4% (40/81) and worsened in 3.7% (3/81). At 6 month, CP class was improved in 16.0% (13/81), not changed in 27.2% (22/81) and worsened in 6.2% (5/81). In multivate analysis, independent predictor associated with improvement of liver dysfunction was only CP class at baseline (p=0.005). Patient with improvement at 3 months was CP class A in 0, CP class B in 13 and CP class C in 1. Patient with improvement at 6 months was CP class A in 1, CP class in 11 and CP class C in 1. Rebleeding after BRTO occurred in 6 patients and all of them had baseline CP class B (p=0.044) Conclusion: Liver dysfunction was not significantly worsened in cases of liver cirrhosis after BRTO procedures. Liver function might be improved in some patients after BRTO.
증례 : 신장 ; Propylthiouracil로 인한 ANCA 양성 혈관염과 동반된 막성 콩팥병증 1예
류광덕 ( Kwang Duck Ryu ),배민정 ( Min Jung Bae ),백동훈 ( Dong Hoon Baek ),신민지 ( Min Ji Shin ),성은영 ( Eun Young Seong ),송상헌 ( Sang Heon Song ),곽임수 ( Ihm Soo Kwak ) 대한내과학회 2011 대한내과학회지 Vol.81 No.3
그레이브스 병을 PTU로 치료하였을 경우 드물게 항중성구 세포질 항체 양성 혈관염이 동반된다는 것은 알려져 있는 사실이다. 혈관염은 대부분 반월상 사구체 신염과 같은 pauci-immune 사구체 신염으로 신장을 침범하게 되지만, 드물게 막성 콩팥병증이 동반된다는 보고 있다. 이는 자가면역 갑상선질환 치료 과정에서 항갑상선제나 자가면역 갑상선 질환에 의한 이차적 결과로 생각해 볼 수 있고, 일차적인 가능성도 배제할 수 없다. 저자들은 58세 그레이브스 병으로 진단 받고 PTU를 복용하던 환자에서 다발성 폐결절 형태의 항중성구 세포질 항체 양성 혈관염이 발생하고 동시에 막성 콩팥 병증이 진단되어 보고하고자 한다. Vasculitis is one of the rare complications of antithyroid drugs. In most cases, it is associated with ANCA and usually involves more than one organ. Renal involvement is the most common manifestation, and mainly presents as pauci-immune glomerulonephritis. We experienced MPO-ANCA-positive vasculitis and renal involvement presenting as membranous nephropathy following propylthiouracil (PTU) treatment. Cases of MPO-ANCA-positive vasculitis with membranous nephropathy are very uncommon, and the relationship between PTU and glomerulonephritis with immune complex deposition is unclear at present. A 58-year-old woman who had been treated with PTU for Graves` disease was admitted because of dyspnea and general edema. Chest computed tomography showed multiple nodules in both lung fields. The serum level of MPO-ANCA was positive. Initial laboratory findings included proteinuria, hematuria and increased serum creatinine. We thought that MPO-ANCA-associated vasculitis was induced by PTU and renal involvement. Renal biopsy revealed membranous nephropathy. (Korean J Med 2011;81:397-402)
유덕용 ( Ryu Duck-yong ),류재완 ( Ryu Jae-woan ),신창현 ( Shin Chang-hyun ),노태용 ( Noh Tae-yong ),임광현 ( Lim Kwang-hyeon ) 한국구조물진단유지관리공학회 2019 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.23 No.1
The purpose of this study is to investigate the variation of tension of existing tendon by additional tendon installation. As a result of the analysis, it was found that the tension value was decreased overall compared with before tenden reinforcement. The cause of the reduction of tension is presumably due to the effect of reinforcement.
Case Report : Liver Cirrhosis Induced by Porphyria Cutanea Tarda: A Case Report and Review
( Kwang Gyun Lee ),( Jong Jin Hyun ),( Yeon Seok Seo ),( Bora Keum ),( Hyung Joon Yim ),( Yoon Tae Jeen ),( Hong Sik Lee ),( Hoon Jai Chun ),( Chang Duck Kim ),( Ho Sang Ryu ),( Soon Ho Um ) The Editorial Office of Gut and Liver 2010 Gut and Liver Vol.4 No.4
Porphyria cutanea tarda (PCT) is a metabolic disorder that results in a decrease in uroporphyrinogen decarboxylase activity. It is characterized by photosensitivity, bullae formation, and skin pigmentation. There are four types of PCT: acquired, familial, toxic, and hepatoerythropoietic. Uroporphyrin levels are elevated in the urine of PCT patients. PCT can be differentiated from other porphyrias by its clinical characteristics and the porphyrin levels in the serum, erythrocytes, urine, and feces. This metabolic disorder can lead to liver dysfunction as well as histological changes such as fatty infiltration or hepatic fibrosis. PCT rarely manifests as liver cirrhosis. We report herein a case of PCT-induced liver cirrhosis that progressed to hepatic failure. (Gut Liver 2010;4:551-555)