인천지역 TDI 노출 작업자에서 직업성천식 유병율

김형렬,김철우,홍윤철,전형준,김치년,김현수,이지나,신주연,고동희,노재훈 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.2

목적 : TDI는 직업성천식을 일으키는 대표적인 물질로 알려져 있다. 과거 TDI에 노출된 작업자들의 천식 발생률을 5~6%가량 보고하였고, 국내에서도 2-20%에 이르는 유병율을 보고한바 있다. 작업환경이 많이 개선되고, 노출량이 감소된 최근에도 TDI에 의한 직업성천식에 대한 보고가 많이 이루어지고 있어, 이에 대한 적극적인 조사와 진단과정을 통해 유병율을 구하고 질병발생의 변화양상을 파악해 보고자 하였다. 방법 : 인천지역에서 특수건강진단을 수행하는 2개 기관의 TDI 노출 근로자 400여명 중, 사업장의 규모가 50인 이상이며 사업주가 연구진행을 허락한 사업장에서 근무하는 근로자 중 직접적으로 TDI에 노출되는 작업에 종사하는 근로자 170명을 연구대상으로 하였다. 이들에 대해 설문지와 산업의학의사의 면담을 통한 작업관련성 평가를 근거로 정밀대상자를 선정하고 이들에 대해 메타콜린 유발시험, TDI 유발시험 등을 수행하여 직업성천식을 확인하였다. 결과 : 설문조사 결과 11명이 직업과 관련하여 천식증상을 보이는 것으로 나타났고(6.9%), 이중 7명에서 메타콜린 유발검사 양성소견을 보였다. TDI에 의한 특이유발시험 결과 1명에서 양성반응이 나타나, 이 집단에서 TDI에 의한 직업성천식의 유병율은 0.58%였다. 결론 : 과거 국내연구에서 TDI에 의한 직업성천식의 유병율이 2~20%에 이르렀던 데 비해, 본 연구에서는 0.58%로 나타났다. 이는 국외 논문에서도 나타나는 경향으로 작업장 노출량 감소로 점차 발생률이 감소하는 양상을 보이고 있다. 그러나 이미 증상이 나타난 근로자들이 부서를 옮기거나, 직장을 그만둠으로 인해 그 유병율이 과소평가되었을 가능성도 있다고 판단된다. Objecdives: This study was carried out to estimate the prevalence of isocyanate-induced occupational asthma in toluene diisocyanate (TDI) exposed workers. Methods: We examined 170 workers who had been directly exposed to TDI through a medical questionnaire, physical examination, and pulmonary function test. Based on screening examination, workers with suspected occupational asthma were selected for further evaluation such as methacholine and TDI challenge tests. Results: Eleven (6.9%) among 170 workers complained of symptoms of occupational asthma. and 7 among these 11 symptomatic workers showed positive responses to the methacholine challenge test (4.1 %). One spray painter was confirmed as having the TDI induced occupational asthma following a positive response to TDI challenge test. Conclusions: The prevalence of TDI-induced asthma was at 0.58% was lower than that for former studies (2-20%). Improved workplace environment, lower level of TDI exposure compared to the past, and the healthy workers effect may have contributed to this low rate of asthma prevalence in workers with TDI exposure.

Ampicillin/Sulbactam-induced Hemo-lytic Anemia Manifested as Hyperbiliru-binemia in a Preterm Infant

( Joo-hyung Roh ),( Hey-suk Yun ),( Hyun-kyung Park ),( Hyun Ju Lee ),( Chang-ryul Kim ),( Tae-hee Han ) 대한주산의학회 2016 大韓周産醫學會雜誌 Vol.27 No.3

A female was born at 36⁺⁵ weeks of gestation with a birth weight of 2,120 g. Apgar score was 7 at 1 minute and 9 at 5 minutes. Shortly after birth, tachypnea, chest retraction, and a severe build-up of oral secretions were noted. Her blood type was A⁺ and initial hemoglobin was 17.5 g/dl. Her mother was A⁺ blood type. Ampicillin/Sulbactam and gentamicin were started empirically. At 8th day of admission, laboratory results showed hemolytic anemia. Exchange transfusion was performed along with intravenous immunoglobulin and hydrocortisone. After 2 days, the patient’s clinical and laboratory conditions improved. Column hemagglutination assay revealed that the patient’s hemolysis was due to ampicillin/sulbactam.

합성곱 신경망 기반 분류 모델의 화재 예측 성능 분석

노주형(Joo-Hyung Roh),민세홍(Se-Hong Min),공민석(Min-Suk Kong) 한국화재소방학회 2022 한국화재소방학회논문지 Vol.36 No.6

본 연구에서는 화재 안전 향상을 위한 엣지 컴퓨팅(edge computing) 기반 화재감지시스템에 적용 가능한 합성곱 신경망 기반 이미지 분류 모델들인 MobileNetV2, ResNet101, EfficientNetB0를 이용하여 화재 예측 성능 해석을 수행하였다. 성능평가지표인 정확도, 재현율, 정밀도, F1-score와 혼동 행렬을 이용하여 화재 예측 성능을 비교 분석하였다. 또한 분류 모델의 경량화와 관련한 모델 용량 및 추론시간에 대한 비교 분석을 수행하였다. 비교 분석 결과로서 화재 예측 정확도는 EfficientNetB0 모델이 가장 높았으며 경량성 측면에서는 MobileNetV2가 가장 우수한 것으로 확인하였다. 더하여 화재와 유사한 특징을 갖는 비 화재 이미지인 빛과 연무에 대한 이미지 특성을 추가 학습한 결과, 경량성은 우수하나 예측 성능이 낮은 MobileNetV2의 화재 예측 정확도가 개선되는 것을 확인하였다. In this study, fire prediction performance was analyzed using convolutional neural network (CNN)-based classification models such as MobileNetV2, ResNet101, and EfficientNetB0 applicable to an edge computing-based fire detection system for improving fire safety. The fire prediction performance was evaluated using the performance evaluation measures including accuracy, recall, precision, F1-score, and the confusion matrix. The model size and inference time were assessed in terms of the light-weight classification model for the practical deployment and use. The analysis results confirmed that the EfficientNetB0 model had the highest fire prediction accuracy, and the MobileNetV2 was the best light-weight classification model. Notably, additionally learning the image features about light and haze images having similar features with those of the fire images improved the fire prediction accuracy of the light-weight MobileNetV2 model.

객체 탐지 기법 적용 YCbCr 컬러모델의 화염 영역 검출 특성에 관한 연구

노주형(Joo-Hyung Roh),민세홍(Se-Hong Min),공민석(Min-suk Kong) 한국화재소방학회 2023 한국화재소방학회논문지 Vol.37 No.6

화염 영역 검출을 위한 기존 YCbCr 컬러모델은 다양한 색상의 화염에 대한 낮은 검출 성능과 화염과 유사한 색상의 객체에 대한 오검출 특성을 갖는다. 따라서 본 연구에서는 YCbCr 컬러모델의 화염 영역 검출 성능을 개선하기 위하여 객체 탐지 기법 적용 개선된 YCbCr 컬러모델을 제안하였다. 화염과 유사한 색상을 갖는 객체 영역에 대한 검출을 방지하기 위해 객체 탐지 딥러닝 모델인 YOLOv8을 적용하여 화염 객체 영역을 탐지하고 해당 영역 내에서 화염을 검출하도록 하였다. 또한 화염 영역 검출 성능을 개선하기 위하여 적색 지배형 화염과 황색 지배형 화염을 구분하여 화염을 검출하는 YCbCr 규칙을 적용하였다. 화염 영역 검출 성능을 평가한 결과, 제안된 모델의 intersection over union (IoU) 값이 기존 YCbCr 모델 대비 약 15.4% 향상되었다. 또한 화재 및 비화재 예측성능의 경우 제안된 모델의 정밀도, 재현율, F1-score 값이 기존 YCbCr 모델 대비 각각 15.9%, 28.2%, 24.7%로 개선되었다. The existing YCbCr color model for flame segmentation has a low segmentation performance for various colored flames and mis-segmentation for flame-like colored-object regions. An improved YCbCr color model using an object detection technique is proposed in this study to improve the flame segmentation performance of the existing YCbCr color model. YOLOv8, a deep learning model for object detection, was used to form a bounding box for the flame to prevent the segmentation of the flame-like colored-object region, and flame segmentation in the bounding box was performed. In addition, YCbCr rules were proposed to segment red and yellow flames to improve flame segmentation performance. The performance evaluation showed that the proposed model increased the intersection over union value by approximately 15.4% compared to that of the existing YCbCr model. In terms of the fire prediction performance evaluation, the precision, recall, and F1-score of the proposed model increased by approximately 15.9%, 28.2%, and 24.7%, respectively.

유아 스마트기기 사용 및 이용수준 현황

노주형(Joo Hyung Roh),이진(Jin Lee),고민숙(Min Suk Koh),김용주(Yong Joo Kim),설인준(In Joon Seol),문진화(Jin Hwa Moon) 대한소아신경학회 2016 대한소아신경학회지 Vol.24 No.3

목적: 스마트기기의 보편적인 사용으로 많은 영유아들이 이를 손쉽게 접하게 되었다. 그러나 영유아기 아동들의 스마트기기 사용 현황과 그 영향에 대해서는 아직 체계적인 연구결과가 많지 않다. 본 연구의 목적은 유아들의 스마트기기 사용현황과 이용수준을 재파악하고자 하는 것이다. 방법: 연구대상은 구리시와 남양주, 서울의 어린이집 4곳에 등원 중인 만 3-5세 유아 130명(남:여=71:59) 이었으며, 질문도구지에 대한 부모의 응답을 분석하였다. 질문도구는 앞선 연구들에서 사용되었던 ‘유아의 스마트기기 사용 현황에 대한 질문지’와 ‘부모용 유아 스마트기기 이용수준 척도’를 이용하였다. 결과: 최초의 스마트기기 사용시기는 만 1-2세가 가장 많았으며 (37.7%), 사용빈도는 주 1-2 회가 가장 많았고(35.4%), 하루 중 총 사용시간은 주중(57.6%) 또는 주말(53.8%) 모두 1시간 미만인 경우가 많았다. 주 사용목적은 동영상 시청이었다(73.9%). 대부분의 어머니들이 스마트기기의 사용자제를 위한 노력을 시도하고 있으며(66.1%), 유아에게 미치는 영향은 부정적으로 평가하였다(53.0%). 미디어이용수준척도의 평균점수는 3.34점으로(1-5점 척도) 보통 정도의 이용수준을 보였다. 추가적으로 사용빈도(F), 최대사용시간(Tmax)을 이용하여 이 두 값의 곱인 FxTmax 값을 구하고 이를 인구학적 변수에 따라 비교하였다. 형제가 있는 경우 그렇지 않은 경우보다 Tmax 가 의미 있게 더 높았으며, 5세 유아 군이 3세 또는 4세 유아군에 비하여 Tmax 또는 FxTmax 값이 의미 있게 더 높았다. 결론: 유아의 성장에 따라 스마트기기 사용시간의 조절과 바람직한 이용수준에 대한 지도가 더 필요하며, 스마트기기 사용이 유아의 발달에 미치는 영향에 대한 추가적인 연구가 필요하다. Purpose: With the widespread use of the smartphone, many preschool children have gained easy access to the smartphone or tablet PC (Personal computer). However, there are not much studies about the current status of smartphones usage or in-fluence. The purpose of this study was to re-evaluate the current state of the smart-phone usage and utilization levels in preschool children. Methods: Total 130 preschool children between 3-5 years old were enrolled from four daycare centers at Guri, Namyangju and Seoul (M:F=71:59). We used 1) the questionnaires for usage of smartphones and 2) the scales for use of smartphones by parents, which developed by preceding publications. Results: The most common age at first use of smartphones was between 1 and 2 years old (37.7%) and the most common frequency of using smartphones was 1-2 times a week (35.4%). Most children used smart devices less than an hour both in weekday (57.6%) and weekend (53.8%). The main purpose of usage was watching videos (73.9%). Average score of smart device utilization level was 3.34 (1-5 points scale), which showing moderate level. In addition, we analyzed the frequency of usage (F), maximal usage time (Tmax), and the product of F and Tmax (FxTmax) score by demographic data. The children having siblings showed significantly higher Tmax. 5 years old group showed higher Tmax and FxTmax than 3 or 4 year old group. Conclusion: As preschool children grow up, more guidance for the smartphone usage time and desirable usage level will be needed. The effects of smartphone usage and diverse developmental outcome should be further investigated.

객체탐지 알고리즘 기반 실시간 화재 감지에 관한 기초 연구

노주형(Joo Hyung Roh),김유경(Yu Kyung Kim),이민주(Min Joo Lee),공민석(Min Suk Kong) 한국화재소방학회 2023 한국화재소방학회 학술대회 논문집 Vol.2023 No.1

Glomerulonephritis following COVID-19 infection or vaccination: a multicenter study in South Korea

( Hyung Woo Kim ),( Eun Hwa Kim ),( Yun Ho Roh ),( Young Su Joo ),( Minseob Eom ),( Han Seong Kim ),( Mi Seon Kang ),( Hoein Jeong ),( Beom Jin Lim ),( Seung Hyeok Han ),( Minsun Jung ) 대한신장학회 2024 Kidney Research and Clinical Practice Vol.43 No.2

Background: Despite the widespread impact of the severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019, COVID-19) and vaccination in South Korea, our understanding of kidney diseases following these events remains limited. We aimed to address this gap by investigating the characteristics of glomerular diseases following the COVID-19 infection and vaccination in South Korea. Methods: Data from multiple centers were used to identify de novo glomerulonephritis (GN) cases with suspected onset following COVID-19 infection or vaccination. Retrospective surveys were used to determine the COVID-19-related histories of patients who were initially not implicated. Bayesian structural time series and autoregressive integrated moving average models were used to determine causality. Results: Glomerular diseases occurred shortly after the infection or vaccination. The most prevalent postinfection GN was podocytopathy (42.9%), comprising primary focal segmental glomerulosclerosis and minimal change disease, whereas postvaccination GN mainly included immunoglobulin A nephropathy (IgAN; 57.9%) and Henoch-Schönlein purpura nephritis (HSP; 15.8%). No patient progressed to end-stage kidney disease. Among the patients who were initially not implicated, nine patients with IgAN/HSP were recently vaccinated against COVID-19. The proportion of glomerular diseases changed during the pandemic in South Korea, with an increase in acute interstitial nephritis and a decrease in pauci-immune crescentic GN. Conclusion: This study showed the characteristics of GNs following COVID-19 infection or vaccination in South Korea. Understanding these associations is crucial for developing effective patient management and vaccination strategies. Further investigation is required to fully comprehend COVID-19’s impact on GN.

Associations between Depression, Anxiety, Hostility and Fighting Spirit among Cancer Patients in a Cancer Center inKorea

Joo hyung Kim,Jae-Kyung Roh,Jeoung-Soon Yoon,Suk-Jeong Lee,Dong-Yeon Lee 대한암학회 2003 Cancer Research and Treatment Vol.35 No.5

Purpose: The aim of this study was to examine the associationsbetween depression, anxiety, hostility andfighting spirit among patients with stomach, colorectalor breast cancer.Materials and Methods: 223 patients, diagnosed as withstomach, colorectal or breast cancer, undergoing chemotherapyor follow up care, were the subjects of the study.The study design was cross-sectional at the time of thesurvey. The degrees of depression, anxiety and hostilityof the patients were assessed by the SCL-90-R scores,and the fighting spirit was measured by the MentalAdjustment to Cancer (MAC) scale score.Results: The scores of anxiety and hostility of the patientsat younger age were higher than those at older age(p〈0.01). The patients with metastasis were more depressedthan those without it (p〈0.01). There was a negativeassociation between depression and fighting spirit (p〈0.001).Conclusion: The study showed the more depressedcancer patients had lower fighting spirit score, which wasknown to be one of the most active psychosocial contributorsinadjusting to cancer and survival. (Cancer Res Treat. 2003;35:411-418)

Single-port robot-assisted prosthetic breast reconstruction with the da Vinci SP Surgical System: first clinical report

Joo, Oh Young,Song, Seung Yong,Park, Hyung Seok,Roh, Tai Suk Korean Society of Plastic and Reconstructive Surge 2021 Archives of Plastic Surgery Vol.48 No.2

Robot-assisted nipple-sparing mastectomy with immediate reconstruction is currently performed in an attempt to seek smaller and indistinct incisions. Robotic surgery system has been evolving under the concept of minimal invasive technique which is a recent trend in surgery. One of the latest version is the da Vinci SP Surgical System (Intuitive Surgical). In this report, we will share our experiences. Two patients underwent robot-assisted nipple-sparing mastectomy, each followed by immediate robot-assisted expander insertion and prepectoral direct-to-implant breast reconstruction, respectively. There was no open conversion or major postoperative complication. One patient experienced mild infection, which was resolved by intravenous antibiotic treatment. Simple docking process, multi-joint instruments, and thirdarm functionality are among the new surgical system's advantages. The present cases suggest that robot-assisted nipple-sparing mastectomy with immediate reconstruction using the da Vinci SP Surgical System is feasible and safe. The promising features and potential application of da Vinci SP in breast reconstruction need further study.

Flexor Tenorrhaphy using Absorbable Suture Materials

Hyung Joo Kang,Dong Chul Lee,Jin Soo Kim,Sae Hwi Ki,Si Young Roh,Jae Won Yang 대한성형외과학회 2012 Archives of Plastic Surgery Vol.39 No.4

Background Nonabsorbable sutures are favorable for repairing flexor tendons. However,absorbable sutures have performed favorably in an animal model. Methods Two-strand sutures using the interlocking modified Kessler method with polydioxanone absorbable sutures 4-0 were used to repair completely ruptured flexor tendons in 55 fingers from 41 consecutive patients. The medical records of average 42 follow up weeks were analyzed retrospectively. The data analyzed using the chi-squared test, and Fisher’s exact test was used for postoperative complications. The results were compared with those of other studies. Results Among the index, middle, ring, and little fingers were injured in 9, 17, 16, and 13 fingers, respectively. The injury levels varied from zone 1 to 5. Of the 55 digits in our study, there were 26 (47%) isolated flexor digitorum profundus (FDP) injuries and 29 (53%)combined FDP and with flexor digitorum superficialis injuries. Pulley repair was also conducted. Concomitant injuries of blood vessels and nerves were found in 17 patients (23 fingers); nerve injuries occurred in 5 patients (10 fingers). Two patients had ruptures (3.6%), and one patient had two adhesions (3.6%). Using the original Strickland criteria, all the patients were assessed to be excellent or good. Also, fibrosis and long-term foreign body tissue reactions such as stitch granuloma were less likely occurred in our study. Compared to the Cullen’s report that used nonabsorbable sutures, there was no significant difference in the rupture or adhesion rates. Conclusions Therefore, this study suggests that appropriate absorbable core sutures can be used safely for flexor tendon repairs.