소아기 내과계 질환의 통계적 관찰

서종진,이건수,정용헌 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

Statistical analysis of medical in-patients of pediatric age from Jan. 1989 to Dec. 1989 was assessed to find out the general patterns and trends of childhood medical diseases at Chungnam National University Hospital. The results are as follows : 1. Total numbers of in-patients were 1266, of which 782 were male and 484 were female. The ratio of male to female was 1.62 : 1. 2. According to the observation on patient distribution by age and departments, the most frequent age group was under 1 month in Pediatrics, 10-15 years of age in Psychiatrt, Rehabilitation Medicine and Neurology, 5-10 years of age in Dermatology. 3. According to the observation on the duraton of admission, more than half were admitted less than 7 days(53%) and most patients were less than 21 days (90.4%). 4. The most common disease of in-patients was pneumonia(8.1%) followed by neonatal hapoxia, prematurity, and acute gastroenteritis. The most common organ system(disease category) was neonatal diseases(26.4%) followed by respiratory diseases(17.4%) and infectious diseases(11.9%). 5. Average duration of admission was 10.9 days. That of Pediatrics was 10.2 days, Dermatology 7.0 days, Rehabilitation Medicine 43 days, Neurology 12.8 days and Psychiatry 20 days.

수액 세트의 Drip Chamber를 이용한 상부소화관의 이물 제거 1예

서종훈,양미진,이진성,이상호,김정원 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

In the upper gastrointestinal tract, in particular, there are parts consisting of esophageal sphincter muscles to carry out physiologic functions, which causes impairments when removed, as well as such complications as mucosal injuries, bleeding and even perforations in the case of foreign bodies with large size and/or sharp angles. Therefore, it is essential to use an appropriate type of supplementary instrument for a safe procedure. Frequently utilized supplementary instruments are overtube, protector hood, latex glove and transparent cap. We report a case in which authors were successful in removing a watch bend consisting of metal ring from gastric body while using a modification of a widely available drip chamber of fluid set attached to vertical end of endoscopic device.

Graves병 환아 혈청내 갑상선 자가항체의 임상적 의의

서종진 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2

The prevalence of antithyroid autoantibodies and the relationship between the presence of autoantibodies and response to antithyroid medication were studied in 20 children with Graves' disease who were seen at the Department of Pediatrics, Chungnam National University Hospital from March 1985 to February 1990. The circulating AMA, ATA and TRAb were detected in 80%, 45% and 90% respectively. The TRAb was measured by TBII, and the mean value was 41.1±20.9%. The results of thyroid function test at 3 and 6 months after antithyroid medication showed higher euthyroid conversion rate among the patient group without AMA or ATA than the patient group with AMA and ATA. The mean TSH level after 6 months' antithyroid medication was suppressed significantly more in the patient group with AMA and ATA than in the patient group without AMA or ATA. These result showed that the prevalence of autoantibodies in childhood Graves' disease was almost similar to that of adults, and the treatment response of initial 6 months' period was better in patients without AMA or ATA. The relapse rate could not be elucidated due to short-term follow-up period.

효소고정화막과 반투막성질의 PVA적층막 제조 및 산소센서에서의 특성

서종원,김태진,정용섭,윤정원 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

The oxygen electrode of biosensor needs enzyme immobilized membrane and dialysis membrane for measurement of oxygen concentration, which in solution after enzyme reaction with its substrate. The one-layer PVA laminated CTA/PCL membrane was developed for oxygen electrode of biosensor. Enzymes have immobilized on cellulose triacetate/polycarprolactone membrane by CDI method, and laminated with polyvinyl alcohol, aldehyde and acid. This membrane immobilized with glucose oxidase, ascorbate oxidase, pyruvate oxidase and alcohol oxidase by CDI mehod, and PVA laminated CTA/PCL membrane have been tested with various concentration of substrates of enzymes by use of YSI oxygen sensor. Under 5-10mmol substrates become 0.37-0.83μA(r=0.995) currents, and about 56% of glucose oxidase activity was remained after 8 weeks, others were remained very low. SEM shows smooth surface and tightly attached PVA on enzyme immobilized CTA/PCL membrane.

자성유체를 이용한 평판 디스플레이에 관한 연구

徐鍾旭,金眞煥 弘益大學校 科學基術硏究所 1999 科學技術硏究論文集 Vol.10 No.2

In this paper the possibility of using the magnetic fluid for new type of display devices is presented. It has been found that the magnetic fluid initially placed on the electrode can be pushed away from the region by the magnetic field induced by a moderate level of current. As the thickness of the fluid reduces, more of the incident light is reflected from the surface of the electrode resulting in a brighter state of the cell due to the increased surface reflection. A program to simulate the variation of magnetic fluid thickness on the current carrying electrodes has been developed. The CFD(Computational Fluid Dynamics) code developed uses the PDE(Partial Differential Equation) toolbox in MATLAB to calculate the magnetic field distribution around the electrodes. It has been found that the variation of the magnetic fluid surface profile obtained using the developed simulator well fits the experimental results. It has also been found that the speed of the thickness modulation increases as the magnetic permeability decreases.

Conceptual Study for Tissue-Regenerative Biodegradable Magnesium Implant Integrated with Nitric Oxide-Releasing Nanofi bers

Jin‑Kyung Jeon,Hyunseon Seo,Jimin Park,Soo Ji Son,Yeong Rim Kim,Eun Shil Kim,Jong Woong Park,Woong‑Gyo Jung,Hojeong Jeon,Yu‑Chan Kim,Hyun‑Kwang Seok,Jae Ho Shin,Myoung‑Ryul Ok 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.4

The excessive initial corrosion rate of Mg is a critical limitation in the clinical application of biodegradable Mg implantsbecause the device loses its fi xation strength before the fractured bone heals. This study suggests a new approach to overcomethis hurdle by accelerating tissue regeneration instead of delaying the implant biodegradation. As angiogenesis is anessential process in early bone regeneration, a Mg implant coated with electrospun nanofi bers containing nitric oxide (NO),which physiologically promotes angiogenesis, is designed. The integrated device enables adjustable amounts of NO to bestored on the NO donor-conjugated nanofi ber coating, stably delivered, and released to the fractured bone tissue near theimplanted sites. An in vitro corrosion test reveals no adverse eff ect of the released NO on the corrosion behavior of the Mgimplant. Simultaneously, the optimal concentration level of NO released from the implant signifi cantly enhances tube networkformation of human umbilical vein endothelial cells without any cytotoxicity problem. This indicates that angiogenesis canbe accelerated by combining NO-releasing nanofi bers with a Mg implant. With its proven feasibility, the proposed approachcould be a novel solution for the initial stability problem of biodegradable Mg implants, leading to successful bone fi xation.

소아 갑상선종에 대한 임상적 고찰

徐宗振 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

56 Children with goiter who visited Chungnam National Univ. Hospital from Jun. 1986 to Nov. 1987 were studied and the observed clinical data are as follows: 1) Children of more than 10 year of age were 46 cases(82.1%), and the ratio of male and female was 1 : 6. 2) Simple goiter and chronic lymphocytic thyroiditis(CLT) were about 75% of the studied cases and they were the two most important underlying diseases of goiter in childhood. 3) In classification of goiters according to function, the euthyroid goiter was 80.3% of all the studied cases. The hyperthyroid and hypothyroid goiter were 8% and 5.4% each. Among 20 cases of CLT, 14 cases (70.0%) were euthyroid CLT. The hyperthyroid and hypothyroid CLT were 3 cases(15.0%) each, but the abnormalities in thyroid function were not so severe. 4) Goiter, increased sweating, palpitation, easy fatigability and exophthalmos were the common initial symptoms and signs hyperthyroid goiters in descending order. 5) Antithyroid medication with or without thyroxine was given to hyperthyroid patients, and replacement therapy with thyroxine was done for all the hypothyroid goiters. 24.4% of euthyroid goiters were regularly followed up without medication, and the others were given thyroxine.

Substance P의 기니피그 위 유문동 윤상근에 대한 수축 및 전기적 효과

서종옥,이승곤,김종승,전제열,여철호,윤평진 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2

소수성 NaY Zeolite의 합성과 탈알루미나의 특성

서동남,하종필,구상모,이해진,김익진 호서대학교 반도체제조장비국산화연구센터 2000 학술대회 자료집 Vol.2000 No.1

NaY형 Zeolite는 현재 그들의 촉매적 특성과 흡착성 그리고 이온 교환성들을 이용하여 산업에 중요하게 사용되어지고 있다. 본 실험은 고온 스팀을 이용한 방법과 산처리에 의한 방법으로 탈알루미나의 효과를 확인하는 실험을 하였다. 먼저 SiO_2/Al_2O_3 몰비가 4∼6인 합성 NaY zeolite를 분위기 소성로에 넣고 증기발생 장치를 이용하여 500℃에서 고온 스팀을 분위기 소성로에서 일정하게 주입하였다. 에에 따른 결과는 탈알루미나 처리 후의 XRF와 BET의 결과로 탈알루미나 처리에 따라서 SiO_2/Al_2O_3의 몰비가 20.6에서 21까지 증가한 것을 알 수 있으며 또한 BET의 결과에서 탈알루미나 처리에 의해서 비표면적이 증가한 것을 확인할 수 있으며 특히 meso pore area의 증가는 탈알루미나에 의해서 zeolite의 골격구조가 일부 파괴되었음을 알 수 있다.

특허권 강화는 기술혁신을 촉진하는가? : 한국의 특허법 개혁을 중심으로 Evidence From the Korean Patent Law Reforms

徐煥周,鄭東進,宋鍾國 한국국제경제학회 2004 국제경제연구 Vol.10 No.2

1970년대 말 이후 취해진 미국의 일련의 특허권 개혁과 1994년에 체결된 TRIPS협약을 계기로 특허권 강화와 기술혁신간의 상관관계에 대한 수많은 실증연구가 1990년대 들어 행하여지고 있다. 그러나 최근의 실증연구결과들은 특허권강화가 기술혁신을 촉진하는 유효한 수단인가에 대해서 명확한 결론을 내리지 못하고 있어, '특허의 역설(Patent paradox)'이라 불리고 있다. 본 연구는 우리나라의 특허 및 연구개발 지출 자료를 활용하여 특허권 강화(특허법개혁)가 기술혁신활동에 유효한 인센티브로 작용하는 지를 살펴보았다. 분석결과 1980년대 말의 특허법 7차 개정과 1990년대 중반의 11차 개정이 연구개발 지출과 특허출원건수로 측정한 기술혁신활동에 긍정적으로 작용하였음을 발견하였다. 그러나 우리의 추정방법이 제도개혁의 직접적인 영향만을 추정하는 것이 아니라 여타의 거시적 충격까지 포함할 가능성이 있기 때문에 조심스러운 해석을 요한다. By influencing the incentives to innovate, the strengthening of patents may affect economic growth in important way. An important question for many countries is whether patent law reforms induce more innovation. This paper examines the role of patents in innovation, utilizing Korean data on patent applications, expenditure of R&D, sales and concentration ratio. The evidence suggests that the strengthening of patents was a significant determinant of innovation in Korea. However, in our estimations, we do not completely eliminate the effects of other macro shocks. Therefore, we interpretate our results as representing an "upper bound" of Korean firms' responses to patent law reforms.