複制中國書畵文物的歷史和現狀及複制工藝技術

曹靜樓,郭文林 용인대학교 박물관 2003 丹豪文化硏究 Vol.- No.7

Imno(臨摹 copying) of the painting and writing in China is combined result of many closely-related elements that include Chinese cultural tradition and philosophy and substantial characteristics of Chinese paintings and calligraphy. ① Chinese rulers throughout history, under the so-called theory of 'Sungkyohuajoinlon' (成敎化助人論 to help people by educating them) often relied on paintings as a means to strengthen their governing foundation while using them to educate their subjects and people. For example, Hyojaeuisudo ≪孝子義士圖, a painting of devoted children and righteous people≫ meant the loyalty and obedience, Yulyujun ≪烈女傳, a story of virtuous women≫ was used to signify the importance of chastity in a feudal society. Paintings with such themes were met with the rulers ethics and, with the supports from the rulers, used as a means to publicize their ethics and educate their subjects and people. ② There were many rulers who were good at or loved the writing and painting in ancient China. Among many, Taizhong Li Shimin at Tang Dynasty(唐 太宗 李世民), Xianzhong Li Jiangji(玄宗 李降基), Huizhong Jo Ji at Song Dynasty (宋代 徽宗 趙佶), Xunzhong Zhu Jianshen at Ming Dynasty(明代 憲宗 朱見深), Gaozhong Hong Li at Qing Dynasty(靑代 高宗 弘力) are such examples. Development of painting and writing arts in China was achieved with the interests of rulers in them, and important eras that marked the history of Chinese painting and writing arts were created. Until the year of Huizhong(徽宗), the level of painting and writing was an important condition in deciding a governmental position. However, in ancient times, since there was a limited number of painting and writing works and lack of printing technology, emperors and high officials of literature had to be satisfied only with enjoying them and hoped to possess them. In the government, a special bureau was established to educate and raise the professionals who could duplicate the paintings and writings. This tendency influenced the society as a whole, and the atmosphere of reproduction of painting and writing works by duplication gradually culminated. ③ Chinese philosophy had also influenced their painting and writing arts. Chinese drawings pursue objectivity and has an expression style of Chuninhapil (天人合一, heaven and human beings are one). In Chinese drawings, artists describe the natural object and at the same time transfer their mind and feelings in them. Nature in the drawings is not just the nature as it is seen, but it is the nature observed and attained by artists and drawn from deep inside of artists. When people learn Chinese drawings for the first time, they are not taught how to describe the forms as in the western style but receive formative train in that people enter into the nature and sketch. This is the reason why artists, when copying the works in the past, are able to obtain the feelings of nature and learn various brush techniques that are applied in Chinese drawings. Therefore, copying is a significant method to learn Chinese drawings. For example, SunMyo(線描 line description) has a certain form, and a famous ShipPalMyo (十八描 18 descriptions) including ChulSunMyo(鐵線描), YuSaMyo (遊絲描), NanYupMyo (蘭葉描), YuYupMyo (柳葉描), JoEuiMyo (曹衣描) was created. Since these lines don't exist in natural objects, it is impossible to learn them through sketching. They can be learned only by copying the works in the past, in which they equates with various drawing styles that are applied when painting various objects. For example, JunBup(준法 technique to express the feel of the surface as it is) used for landscape drawings is helpful when expressing the touch and feelings of various rocks. For example, BuByukJun(斧劈준) or WooJumJun(雨點준) are good for expressing the characteristics of Chinese northern landscape, PiMaJun(披痲준) or MiJumJun(米點준) for Chinese southern landscape. This JunBup does not exist in natural objects such as mountain or rock, and artists can learn the right JunBup for various rocks through copying the works of the past. ④ Traditional thinking that stresses the relationship between a teacher and disciple in Chinese culture had also influenced Chinese painting and writing arts. When people beging to learn Chinese drawings, they must copy the works of their teacher. Therefore, when other people look at the drawings, they know who is with which teacher and which school. The drawings of certain artists are used as an educational purpose when students learn drawings for copying. For example, SaSaengJinBuDo ≪寫生珍禽圖≫ by Huang Jun (黃筌) in Song Dynasty was inherited to his son and learned as a work for copying. Each word in Immo(臨摹), according to the explanation in the ancient literature, has a separate meaning, Mo(摹 to copy) means Tap(榻 to copy), and Im(臨 to overlook) means Sa(寫 to write). Current meaning of Im(臨) is, while looking at the original drawing, to understand deeply and in details. When doing it, not only the techniques of brush, ink, and color but also the compositional characteristics should be thoroughly studied in order to completely familiarize with the form and line of the original drawing. And then, it has to be reproduced on another paper in one moment, and the copy does not have to be and can not be exactly the same as the original. Im(臨), based upon the complete understanding of the original, is to complete the copy with one energy without looking at the original. Mo(摹) is, while placing a thin paper right over the ancient drawing book, to copy both thick and thin lines, and Mo(摹)'s meaning in copying of a painting (摹畵) is the same. In ancient times, Mo(摹) was replaced with Mo(模 to imitate) or Mu(撫 to stroke). In other words, a transparent paper is placed over the original, the first copy is accurately made, the original is removed, drawing paper is placed over the first copy, and drawing is done in details while referring the original. Two words, Im(臨) and Mo(摹), originally impose a separate meaning and cant be one word, but they are habitually used as one word. Mo(摹) used in current China cant be Im (臨) but has to be called as Motap (摹榻). Especially, copying and counterfeiting are fundamentally different and can't be used as same meaning. The purpose of copying is a complete reproduction of energy and form of the original, and it is to conserve and actively publicize the original. The purpose of counterfeiting is to gain profits while falsely stating someone else's name as his or her own, and it includes the meaning of damaging the original. They also have difference in using the technique. The work of copying is faithful to the original and completely reproduce the smallest detail. People producing the copies must perfectly understand the spirit and form of the original, and successful copies should contain both the form and spirit. Rather, counterfeit is not based on the original but freely drawn upon studying a certain brush style of ones own. As a result, artists of counterfeit who are very well aware of the brush style used by the original artist are famous artists and might be the person who lives the same period with or the disciple of the original artist. Paintings produced for the purpose of counterfeiting possibly be the fraud and trouble to judge the authenticity of the work in a later period. Copying project of painting and writing at the Palace Museum is to replace the original work with the copied one by the time of difficulty in exhibiting the original, which is the best way to conserve the original. Copying of ancient paintings and calligraphy does not only mean the line description, outlining, coloring), or usage of ink. It is a very difficult process of re-creation that requires sincerity and efforts. Since the Palace Museum has started the copying project in 1950s, top artists are putting their efforts to copy and duplicate highly-valuable cultural artifacts. They have copied famous drawings of Qin, Tang, Song and Yuan dynasty with strict working attitude and exquisite techniques. Famous Chungmyungsanghudo≪淸明上河圖≫, Hanheejaeyayeondo ≪韓熙載夜宴圖≫, Guasukpyungwondo≪과石平遠圖≫ by Kwak Hee(郭熙), and Chunggeumdo ≪聽琴圖≫ by Jo Gil (趙佶) are such examples. Not many professionals are working for the copies in China. There were few in the Shanghai(上海) and Nanjing(南京) Museum during 1980s, but they are no longer there with various reasons. In Dunhuang(敦煌) and Xian (西安), frescoes are mainly being replicated. The quality of professionals who work to copy at the Palace Museum are the best in its technique and size and cannot be compared to other museums. Copying one painting successfully requires a lot of preparations. When producing the copies, it takes from few days to several years. Thus, safety of the original should be guaranteed, and there should not be done even a small damage. But observing the original should be convenient, and copying process should be progressed with many attentions.

Adaptive Controller Design for Switched Stochastic Nonlinear Systems Subject to Unknown Dead-zone Input via New Type of Network Approach

Wen-Jing He,Shan-Liang Zhu,Na Li,Yu-Qun Han 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.2

In this article, adaptive tracking control for a class of switched stochastic nonlinear systems subject to unknown dead-zone input using multi-dimensional Taylor network (MTN) is studied. Firstly, the characteristic function is introduced to convert the nonlinearity of the input dead-zone into a linear model. Secondly, a novel adaptive control method based on the backstepping recursive design technique is proposed, which combines MTN and common Lyapunov functions (CLFs). Significantly, a method to reduce the computational complexity of switched stochastic nonlinear systems is proposed for the first time, which introduces characteristic function and MTN technology. The result makes clear that the proposed controller can ensure all signals of the closed-loop system are bounded in probability, and the output of the system can track reference signal well. Finally, the effectiveness of proposed control method is verified by simulation results.

Efficient extraction and separation of vanadium and chromium in high chromium vanadium slag by sodium salt roasting-(NH4)2SO4 leaching

Jing Wen,Tao Jiang,Yingzhe Xu,Jing Cao,Xiangxin Xue 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.71 No.-

A novelty process based on sodium salt roasting-(NH4)2SO4 leaching was proposed to extract vanadiumand chromium in high chromium vanadium slag (HCVS). V2O5 and Cr2O3 was then prepared. The effectsof roasting and leaching conditions on vanadium and chromium extraction behavior were studiedsystematically and completely. Vanadium precipitation conditions and chromium reduction conditionswere optimized further. 94.6% vanadium and 96.5% chromium were extracted when HCVS and Na2CO3were mixed in the molar ratio of n(Na2CO3)/n(V2O3 + Cr2O3) of 2.5, then leached in 30 g/L (NH4)2SO4solution. 94.8% vanadium was precipitated as ammonium polyvanadate (APV) just by adjusting theleaching liquid pH at 4.5, almost all chromium was remained in liquid, achieving the efficient separationof vanadium and chromium. Chromium was then recovered by reduction and precipitation. More than99% chromium was reduced when Na2S2O5 was added in m(Na2S2O5)/m[Cr(VI)] above 3. By roasting thedeposits of vanadium and chromium respectively, 91.49% V2O5 and 89.89% Cr2O3 were obtained. Thesupernatant after vanadium and chromium extraction containing NH4+ could be recycled as the newleaching medium with some new (NH4)2SO4 added, which greatly reduced the discharge of ammonianitrogenwastewater and made the whole process more environmentally friendly.

ORiginal Article : Tryptase and Protease-Activated Receptor 2 Expression Levels in Irritable Bowel Syndrome

( Wen Jing Liang ),( Guo Zhang ),( He Sheng Luo ),( Lie Xin Liang ),( Dan Huang ),( Fa Can Zhang ) 대한간학회 2016 Gut and Liver Vol.10 No.3

Background/Aims: Previous studies have revealed that mast cells (MCs) may activate the protease-activated receptors and release of neuropeptides involved in the pathogenesis of irritable bowel syndrome (IBS). The levels of proteaseactivated receptor 2 (PAR-2) and tryptase can contribute to understanding the pathogenesis of IBS. Methods: Colonoscopic biopsies were performed of 38 subjects (20 with IBSdiarrhea [IBS-D], eight with IBS-constipation [IBS-C], and 10 healthy volunteers). The mRNA and protein levels of tryptase and PAR-2 were assessed by real-time PCR and Western blot. The levels of vasoactive intestinal peptide (VIP), substance P (SP), and calcitonin gene-related peptide (CGRP) were measured by immunohistochemistry, and MCs were counted by toluidine blue staining. Results: Significant increases in the mRNA expression of tryptase (p<0.05, IBS-D, IBS-C vs control) and PAR-2 (p<0.05, IBS-D, IBS-C vs control) and in the tryptase protein level (p<0.05, IBS-D, IBS-C vs control) were detected in IBS. Elevations of MCs, CGRP, VIP and SP (p<0.05, IBS-D vs control) were observed for IBS-D only. Conclusions: Tryptase levels may upregulate the function of PAR- 2, resulting in the release of neuropeptide and they were correlated with clinical symptoms associated with IBS. (Gut Liver 2016;10:382-390)

Biological Synthesis of Silver and Gold Nanoparticles Using Xanthium strumarium Extract and Their Biological Activities

WEN JING,Bipinchandra K. SALUNKE,Beom Soo KIM 한국생물공학회 2015 한국생물공학회 학술대회 Vol.2015 No.4

High Resolution Melting Analysis for Epidermal Growth Factor Receptor Mutations in Formalin-fixed Paraffin-embedded Tissue and Plasma Free DNA from Non-small Cell Lung Cancer Patients

Jing, Chang-Wen,Wang, Zhuo,Cao, Hai-Xia,Ma, Rong,Wu, Jian-Zhong Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

Background:The aim of the research was to explore a cost effective, fast, easy to perform, and sensitive method for epidermal growth factor receptor (EGFR) mutation testing. Methods: High resolution melting analysis (HRM) was introduced to evaluate the efficacy of the analysis for dectecting EGFR mutations in exons 18 to 21 using formalin-fixed paraffin-embedded (FFPE) tissues and plasma free DNA from 120 patients. Results: The total EGFR mutation rate was 37.5% (45/120) detected by direct sequencing. There were 48 mutations in 120 FFPE tissues assessed by HRM. For plasma free DNA, the EGFR mutation rate was 25.8% (31/120). The sensitivity of HRM assays in FFPE samples was 100% by HRM. There was a low false-positive mutation rate but a high false-negative rate in plasma free DNA detected by HRM. Conclusions: Our results show that HRM analysis has the advantage of small tumor sample need. HRM applied with plasma free DNA showed a high false-negative rate but a low false-positive rate. Further research into appropriate methods and analysis needs to be performed before HRM for plasma free DNA could be accepted as an option in diagnostic or screening settings.

Biosynthesis of graphene‐metal nanocomposites using plant extract and their biological activities

Wen, Jing,Salunke, Bipinchandra K,Kim, Beom Soo WILEY & SONS 2017 Journal of Chemical Technology & Biotechnology Vol. No.

<P>CONCLUSION: The present results show that GN/Ag and GN/Au nanocomposites can be ecofriendly synthesized using Xanthium strumarium leaf extract. The graphene/metal nanocomposites produced may be less-toxic, biocompatible, and useful for bioapplications. (C) 2016 Society of Chemical Industry</P>

Genomic Screening for Targets Regulated by Berberine in Breast Cancer Cells

Wen, Chun-Jie,Wu, Lan-Xiang,Fu, Li-Juan,Yu, Jing,Zhang, Yi-Wen,Zhang, Xue,Zhou, Hong-Hao Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

Berberine, a common isoquinoline alkaloid, has been shown to possess anti-cancer activities. However, the underlying molecular mechanisms are still not completely understood. In the current study, we investigated the effects of berberine on cell growth, colony formation, cell cycle distribution, and whether it improved the anticancer efficiency of cisplatin and doxorubicin in human breast cancer estrogen receptor positive (ER+) MCF-7 cells and estrogen receptor negative (ER-) MDA-MB-231 cells. Notably, berberine treatment significantly inhibited cell growth and colony formation in the two cell lines, berberine in combination with cisplatin exerting synergistic growth inhibitory effects. Accompanied by decreased growth, berberine induced G1 phase arrest in MCF-7 but not MDA-MB-231 cells. To provide a more detailed understanding of the mechanisms of action of berberine, we performed genome-wide expression profiling of berberine-treated cells using cDNA microarrays. This revealed that there were 3,397 and 2,706 genes regulated by berberine in MCF-7 and MDA-MB-231 cells, respectively. Fene oncology (GO) analysis identified that many of the target genes were involved in regulation of the cell cycle, cell migration, apoptosis, and drug responses. To confirm the microarray data, qPCR analysis was conducted for 10 selected genes based on previously reported associations with breast cancer and GO analysis. In conclusion, berberine exhibits inhibitory effects on breast cancer cells proliferation, which is likely mediated by alteration of gene expression profiles.

Oct4 and Nanog Expression Is Associated With Early Stages of Pancreatic Carcinogenesis

Wen, Jing,Park, Jeong Youp,Park, Kyung Hwa,Chung, Hye Won,Bang, Seungmin,Park, Seung Woo,Song, Si Young Lippincott Williams Wilkins, Inc. 2010 Pancreas Vol.39 No.5

OBJECTIVE:: To characterize the role of Oct4 and Nanog, two important homeobox transcription factors of embryonic development, in pancreatic carcinogenesis. METHODS:: Using a tissue microarray of human pancreatic carcinoma and adjacent noncancerous tissues as well as the N-nitrosobis(2-oxopropyl)amine-induced Syrian golden hamster pancreatic cancer model, we characterized the expression of Oct4 and Nanog. The presence of K-ras mutation with the time course of carcinogenesis in hamster model was also evaluated. RESULTS:: Oct4 expression in metaplastic ducts was significantly stronger than in normal acini and pancreatic carcinoma (P < 0.05). Of 24 cases, 19 (79.2%) showed a strong Oct4 expression in metaplastic ducts. In contrast, only 6 (19.4%) of 31 cancer tissues and 3 (16.7%) of 18 noncancer tissues showed a strong Oct4 expression. Nanog also showed similar patterns as Oct4. Restriction fragment length polymorphism-polymerase chain reaction showed the overt K-ras mutation after the expression of Oct4 in the hamster model. CONCLUSIONS:: The strong expression of Oct4 and Nanog in metaplastic ducts and Oct4 expression preceding Ras mutation suggests that these homeobox transcription factors are associated with the early stage of pancreatic cancer carcinogenesis and may play an important role in that process.

Preferential Induction of CYP1A1 over CYP1B1 in Human Breast Cancer MCF-7 Cells after Exposure to Berberine

Wen, Chun-Jie,Wu, Lan-Xiang,Fu, Li-Juan,Shen, Dong-Ya,Zhang, Xue,Zhang, Yi-Wen,Yu, Jing,Zhou, Hong-Hao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1

Estrogens are considered the major breast cancer risk factor, and the carcinogenic potential of estrogens might be attributed to DNA modification caused by derivatives formed during metabolism. $17{\beta}$-estradiol ($E_2$), the main steroidal estrogen present in women, is metabolized via two major pathways: formation of 2-hydroxyestradiol (2-OH $E_2$) and 4-hydroxyestradiol ($4-OH\;E_2$) through the action of cytochrome P450 (CYP) 1A1 and 1B1, respectively. Previous reports suggested that $2-OH\;E_2$ has putative protective effects, while $4-OH\;E_2$ is genotoxic and has potent carcinogenic activity. Thus, the ratio of $2-OH\;E_2/4-OH\;E_2$ is a critical determinant of the toxicity of $E_2$ in mammary cells. In the present study, we investigated the effects of berberine on the expression profile of the estrogen metabolizing enzymes CYP1A1 and CYP1B1 in breast cancer MCF-7 cells. Berberine treatment produced significant induction of both forms at the level of mRNA expression, but with increased doses produced 16~ to 52~fold greater induction of CYP1A1 mRNA over CYP1B1 mRNA. Furthermore, berberine dramatically increased CYP1A1 protein levels but did not influence CYP1B1 protein levels in MCF-7 cells. In conclusion, we present the first report to show that berberine may provide protection against breast cancer by altering the ratio of CYP1A1/CYP1B1, could redirect $E_2$ metabolism in a more protective pathway in breast cancer MCF-7 cells.