광미를 사용한 폴리머 시멘트 콘크리트의 강도 특성 및 내약품성

이병철,이주경,이윤수,이필호,이구연,전철수 강원대학교 부설 석재복합신소재 제품연구센터 1999 석재연 논문집 Vol.4 No.-

본 연구는 세골재의 일부를 광미로 치환하고 혼화제로 SBR 라택스를 사용하여 폴리머 시멘트 콘크리트 공시체를 제작한 후 강도특성 및 내약품성을 실험적으로 구명한 것이다. 그 결과 광미를 사용하지 않고 P/C비가 10%일 때 압축강도가 323㎏/㎠로 최고 값을 나타냈으며, 휨강도는 P/C비가 증가할수록 증가하여 P/C비가 10%일 때 89㎏/㎠를 나타냈다. 그리고 광미를 사용한 경우는 P/C비가 10%일때 압축강도가 357㎏/㎠, 휨강도가 92㎏/㎠로서 광미를 사용하지 않은 경우보다 높게 나타났다. 한편 10% HCI, 20%, NaOH 10% NaCl 수용액에 공시체를 3, 7, 14, 21, 28일간 침적 시킨 후 중량변화를 측정하여 내약품성을 실험한다. 광미를 사용한 경우가 우수한 내약품성을 나타냈다. 즉광미를 사용하지 않은 경우 P/C=0%일 때 28일 후 중량 변화가 11%였으나 P/C=20%일 때는 2%였고, 광미를 사용한 경우는 P/C=0%일 때 질량 변화가 6%였으나 P/C=20%일 때는 1.5%였으며 20% ,NaOH 10% NaCl 수용액에서는 질량이 증가하는 경향을 보였다. Polymer cement concrete is made by the modifying ordinary cement concrete with polymer additive. Until now polymer cement concrete is not used for the structural member, but it is growing to be considered as developing uses such as a waterproof of roof slab, and a road pavement. The polymer cement concrete, being used for those uses, is superior to the cement concrete against the inorganic, organic acid, salt of acetic acid and organic solvents generally. In this paper, the polymer cement concrete was made by the ratio of 1:1 of sands and metal-mine waste rocks in fine aggregate in order to solve the environmental pollution which causes the social problem by metal-mine waste rocks. It was measured for the compressive strength, flexural strength, and chemicals resistance was tested by dealing with 10% HCI, 20% NaOH and 10% NaCI aqueous solution.

Theoretical Analysis and Performance Prediction of Axial-flow Rotary Separator

Kim, Chul Soo,Lee, Seung Kyu,Lee, Chong Ho 전북대학교 농업과학기술연구소 1985 農大論文集 Vol.16 No.-

脫穀作業은 全般的인 穀物生産 作業體系中에서 차지하는 比重이 크고 많은 勞動力을 必要로 하는 作業으로써 오늘날 先進國에서는 콤바인의 穀物 收護·脫穀作業에 널리 利用되고 있으며 그 利用率이 急激히 增加하고 있는 趨勢이다. 現在 利用되고 있는 콤바인의 穀粒 選烈方式은 重力과 貫性에 依存하는 straw-walker 方式을 採擇하고 있는 바 이는 콤바인의 容量을 制限하는 主要因이 되고 있으며 또한 過度한 穀粒損失의 原因이 된다. 따라서 重力依存度를 낮게함과 同時에 여러가지 種類의 作物狀態에도 安定性이 있는 選別機 開發의 必要性이 壇顧되고 있는 實情이다. Strow-walker 方式을 代替할 수 있는 選別機로는 選別作業에 遠心力을 利用하며 作物의 連續的인 移動을 可能하게 하는 軸流 回轉形 選別機를 들 수 있으며 이것은 憤行의 選別機에 比해 여러가지 長點이 있는 것으로 報告된 바 있다. 國內外의 많은 硏究가들에 依해 새로운 選別機 開發을 위한 여러가지 接近이 試圖되고 있는 바 理論的인 援近보다는 主로 實驗的이고 經驗的인 擺近을 通한 硏究가 盛行하고 있는 實情이다. 그러나 邏別戮內에서의 作物의 擧勳에 關與하는 因子들이 많기 때문에 實驗的인 援近方式으로는 作物擧勳에 關한 斷片的인 情報만을 얻을 수 있을 뿐이므로 作物의 擧勳을 槪括的으로 豫寮하기 爲하여서는 理論的인 擺近이 必要하게 된다. 따라서 本 硏究에서는 水平 圓錐形 軸流 回轉 選別機의 性能과 作物의 擧動을 理論的인 解析을 通하여 豫測하여 同 選別機의 設計要因을 分析하기 爲하여 遂行되었다. 본 硏究에서 分析된 選別機의 骨格은 크림프綱으로 된 圓錐形 選別綱과 그안에서 回轉 圓錐形 로우터로 되어 있으며 回轉로우터에는 作物에 回轉力을 주기 위한 級齒가 螺旋形으로 排列되어 있다. 本 硏究에서는 選別機 內에서의 作物의 移動에 關한 運動方程式과 짚으로부터 穀粒의 選別過程에 對한 方程式等이 誘導되었으며 컴퓨터 프로그램에 依하여 이 方程式들의 解를 求하였다. 이들 方程式의 解를 求하여 分析한 結果들은 供試된 圓錐形 選別機가 充分한 選別機能을 發揮할 수 있으며 圓錐角과 로우터의 回轉速度가 選別機內 作物滯留時間에 크게 影響을 미친다는 事實을 보여 주었다. 圓錐角이 20°以上인 境遇에는 回轉速度가 낮더라도 選別機內 作物滯留時間이 너무 짧아 選別機會가 줄어들기 때문에 圓錐角은 15°以內로 設計되어야 할 것으로 判斷되었다. 또한 選別效率을 向上시키기 爲해서는 作物의 軸方向速度를 制御할 수 있는 것을 選別綱 內部面에 附着하는 方法이 바람직할 것으로 思料되었다. 또한 選別綱을 로우터의 回轉方向과 같은 方向으로 回轉시켜 주면 選別效率을 높일 수 있으며 이 境遇 選別綱의 回轉速度가 로우터 回轉速度의 1/5程度일 때 選別效率이 가장 높은 것으로 나타났다. 아울러 分析된 圓錐形 選別機는 比較的 높은 濕度의 作物選別作業에도 適應性이 높을 것으로 思料되었다. The objective of this study was to predict, by theoretical analysis, performance of the horizontal conical separator which has been predetermined. A horizontal conical separator which was designed and tested experimentally by Lee13) was analyzed in this study. A theoretical analysis was made to derive the equation for the motion of the grain while in contact with the outer cone and the equation for the motion of the gain moving through the straw mat. Also, the equation of the probability of grain passage through the perforation of the sieve, which would be affected by the approaching angles of gain to the sieve, was developed. The computer was used to simulate the crop motion and a series of runs was made to obtain predicting information on the separation performance for the different values of system parameters such as cone half angle, angular rotor speed, cone entrance radius, blade pitch and sieve-to-rotor speed ratio. In each run, the crop motion was simulated for several values of one parameter while other parameters were held constant. Results from the computer simulation showed that the horizontal conical rotating separator was capable of subjecting the crop to the desired level of centrifugal acceleration, and that cone angle and angular rotor speed critically influenced crop dwell time within the separator. If the cone half angle were above 20 defee, the dwell time of the crop within the separator would be too short even at low rotor speed. The cone half angle, therefore, should be reduce to be1ow 15degree. Either attaching the helical blades to control the crop axial velocity or rotating the sieve in the same direction to the rotor would result the good separating efficiency. And the axial-flow separator was found to be suitable for the high moisture crops.

동충하초 투여가 최대하 운동 시 지방연소에 미치는 영향

김철우,이용수,이상현,이상호,하민수,윤영조,이재일 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.4

The purpose of this study was to evaluate effects of Cordyceps militaris on fat oxidation during submaximal exercise. Fifteen healthy male collegiate students(ingestion group, N=7; control group, N=8) participated as subjects after signing an informed consent following overnight, subjects completed maximal graded execise test on treadmill to determine exercise intensity(50%VO2max). To evaluate the fat oxidation using indirect calorimeter, it was performed submaximal treadmill to determine exercise lasting. 40min at 50%VO2max after 5day and consumed Cordyceps militaris on separate days. This study was used 2×4 two way repeated ANOVA to analyze physiological and metabolic variables between two groups and metabolic variables between two groups and four exercise periods(l0min, 20min, 30min 40min), and used Scheffe to post-hoc test. Significance was set at α=.05. The results of this study were as followed: First, there were significantly highest in ingestion group for V02, percentage of fat oxidetion(%fat), fat per kilocarolies(Fkcal), and total per kilocarolies(Tkcal)(p<.05), but respiratory exchange ration(RER) and heart rete(HR) were significantly lower in ingestion group(p<.05). Second, RER, %fat, Fkcal were significantly difference in 10, 20, 30, 40min of exercise period(p<.05). This results suggest that there is the effect of Cordyceps militaris on fat oxidation submaximal exercise. Additionally, to evaluate effect of Cordyceps militaris as ergogenic aid, it should be required the future study that included extend subjects, various dosage, and chronic consumption.

Monocyte Chemoattractant Protein-1[MCP1] -2518 유전자 다형성과 주요 우울장애

배치운,이지현,신윤경,김태석,김정진,이창욱,이수정,전태연,이철,백인호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Object : This study was designed to examine the association between monocyte chemoattractant protein-l (MCPl) -2518poly morphism and major depressive disorder (MDD). Methods : Ninety patients with MDD and 114 healthy controls participated in this study. Genotyping was performed by the polymerase chain reaction-restriction fragment length polymorphism method. Results : Genotype and allele distributions in patients with MDD were significantly different from those of the controls, In particular, subjects with the allele A were found to have an increased risk of MDD. Conclusion : The present study suggests that the MCPl -2518 polymorphism may have a potential role for susceptibility to MDD in the Korean population and thus calls for consecutive studies in order to pile up the data with larger different ethnic background.

주요 우울장애가 동반된 혈액 종양 환자에서 Paroxetine의 효과 및 안정성

배치운,이혁재,김정진,이창욱,이수정,이철,백인호 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.4

Objectives : The efficacy and safety of paroxetine in the treatment of depressive disorders are well known, however its efficacy and safety for the treatment of depression in patients with cancer has been poorly studied. This study therefore aimed to evaluate the efficacy and safety of paroxetine in treatment of depressed patients with hematological malignancy (HM). Methods : Fifty-two patients with major depressive disorder (MDD) based on DSM-IV criteria along with comorbid HM were allotted to 8 weeks trial with a flexible-dose regime of paroxetine in combination with their chemotherapy or supportive pharmacotherapy. Treatment response was assessed at baseline, week 2, week 4, and week 8 with 17-item Hamilton Rating Scale for Depression (HAM-D17), Montgomery A sberg Depression Rating Scale (MADRS), and Clinical Global Impression-severity (CGI-S). Side effects were collected with the reported adverse events and laboratory test throughout the study period. Results : 44.2% of 52 patients completed the eight weeks trial. Scores on the HAM-D17, MADRS, and CGI-s (last Observation carried forward, LOCF) at baseline were significantly reduced with mean reduction of 30.5%, 32.8%, and 39.1%, respectively, after 8 weeks treatment with paroxetine. Forty-six patients (88.5%) reported at least one adverse event. The most common adverse event observed in this study was nausea and no serious adverse event was found. Conclusion : In this preliminary study, overall results showed paroxetine could be used for the treatment of depressed patients with HM, but more controlled study is needed to confirm the efficacy and safety of paroxetine in this area.

당뇨병 환자에서 혈장 Thrombin-Antithrombin Ⅲ 및 Plasmin-α_2-Plasmin Inhibitor 복합체의 임상적 의의

김경욱,김은숙,정상수,윤수지,박우일,이준희,남수연,안철우,문병수,김경래,차봉수,송영득,임승길,이현철,허갑범 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.5

연구배경:당뇨병 환자에서 혈액응고 및 섬유소용해 체계의 이상경향이 있어 그 결과로 여러 혈관합병증의 발생위험이 높다는 사실은 널리 알려져 있다. 그 기전은 아직 확실히 밝혀지지 않았으나, 고혈당으로 인한 혈장 단백질들의 비효소성 당화작용이나 산화성 스트레스로 인한 유리 라티칼 작용으로 응고항진이나 섬유소용해 활성의 저하를 유발하는 것으로 생각되고 있다. 최근 응고 및 용해인자와 그 억제자의 복합체들의 증가가 이 상태를 비교적 예민하게 반영한다고 알려져 있다. 방법:본 연구에서는 당뇨병 환자 101명과 정상 대조군 20명에서 혈장내 thrombin­antithrombin complex(TAT)와 plasmin­α₂­plasmin inhibitor complex(PIC)를 측정하여 비교하고, 당뇨병 환자에서 미세혈관 합병증과 대혈관합병증의 유무에 따른 차이와, 이미 혈관 질환의 위험인자로 알려져 있는 인자들간의 상관성을 알아보고자 하였다. 결과:1. 환자의 분포를 살펴보면 혈관합병증이 있는 군은 85명, 혈관합병증이 없는 군은 16명이었고, 평균연령은 각각 57.9±14.1세, 49.9±16.6세로 혈관 합병증이 있는 군에서 더 나이가 많았고, 체질량지수는 23.2±3.4㎏/㎡, 24.1±3.4㎏/㎡로 두 군간 유의한 차이는 없었다. 또 두 군간의 혈압 및 HbA1c, 공복혈당 및 인슐린과 C­peptide, 총 콜레스테롤, 중성지방, HDL­콜레스테롤, Lp⒜는 유의한 차이가 없었고, 미세혈관합병증이 있는 군에서 당뇨병의 유병기간이 길었다. 2. TAT 및 PIC의 농도는 정상 대조군에서는 2.8±1.2 ng/mL, 240.4±69.7 ng/mL이었고, 당뇨병 환자군에서는 9.5±22.6 ng/mL, 472.2±258.7 ng/mL이었다. TAT와 PIC 모두 당뇨병 환자군에서 정상 대조군에 비해 유의하게 증가되어 있었고(p<0.001), TAT/PIC ratio는 두 군간 차이가 없었다. 3. 당뇨병 환자의 혈관합병증에 따른 TAT 및 PIC, fibrinogen 농도는 합병증이 없는 군은 각각 4.1±2.4ng/mL, 362.2±272.0ng/mL, 322.7±102.4mg/mL으로 PIC와 fibrinogen의 증가를 보였으나, 연령을 보정한 후에는 통계학적 유의성은 없었다. 또 대혈관 합병증군에서는 각각 6.0±4.9 ng/mL, 507.4±321.6 ng/mL, 427.1±194.7 mg/dL이었으며 미세·대혈관 합병증군에서는 10.4±6.4 ng/mL, 484.8±269.7 ng/mL, 388.4±132.4 mg/dL으로 TAT의 증가를 보였으나 역시 연령을 보정한 후에는 통계학적 유의성은 없었다. 4. 미세혈관합병증군에서 HbA1c(>8%)가 높은 군의 PIC 농도가 유의하게 높았고(p=0.049), 대혈관합병증군에서 HbA1c(>8%)가 높은 군의 총 콜레스테롤 농도가 유의하게 높았다(p=0.042). 5. 총 당뇨병 환자군에서 PIC는 fibrinogen과 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며(r=0.47, 0.31,-0.25), 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다(r=0.67). 결론:이상의 결과에서 혈장 TAT 및 PIC 농도는 당뇨병 환자에서 정상 대조군에 비해 의미있게 증가되어 있었고, 당뇨병 환자군에서는 연령의 증가와 유병기간이 혈액응고항진 및 용해의 장애에 큰 역할을 함을 알 수 있었으며, 총 당뇨병 환자군에 PIC와 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다. 따라서 당뇨병 환자에서 혈액응고 및 용해의 장애가 동반되어 있다고 볼 수 있으며, 혈장 TAT 및 PIC는 혈관합병증으로의 진행을 예측하는 지표로서 유용하리라 생각된다. 또 혈당조절정도와 상관성이 있으므로 혈당조절후에 추적검사를 시행하여 합병증의 예방이 가능한지 추후 연구가 필요하리라 생각된다. Background : Abnormality of coagulation and fibrinolystic system is known as a predisposing factor of vascular complication in diabetes. Although the pathogenesis is not well known, non-enzymatic glycation reaction and the increase in production of free radicals due to an increased oxidative stress may be linked to the hypercoagulibility and hypofibrinolytic activity. As indices of abnormality in coagulation and firinolysis in peripheral blood, plasma thrombin-antithrombin Ⅲ complex (TAT) and plasmin-α_2-plasmin inhibitor complex (PIC) were measured. The purpose of this study was to clarify whether hypercoagulability exists in diabetic patients with or without vascular complication. Methods : In our study, we measured plasma thrombin-antithrombin Ⅲ compelx (TAT) and plasmin-α_2-plasmin inhibit or complex (PIC) in 101 diabetic subjects and 20 controls. Comparing TAT and PIC levels in diabetic microvascular complication group, diabetic macrovascular complication group and controls, we examined correlation between risk factors associated with diabetic vascular complication. Results : 1. The group with diabetic vascular complication was older than group without complication. There was no significant difference in BMI, blood pressure, HbA_ic, blood sugar level, insulin, C-peptide, serum creatinine, total cholesterol, triglyceride, HDL-cholesterol, Lp (a) between two groups. The group with diabetic microvascular complication had longer duration of diabetes. 2. Concentration of TAT and PIC were 2.8±1.2 ng/ mL, 240.4±69.7 ng/ mL in controls and 9.5±22.6 ng/ mL, 472.2±258.7 ng/ mL in diabetic patients, respectively. TAT and PIC were significantly higher in diabetic patients than in control (p<0.001). But TAT/PIC ratio was no significant difference between two groups. 3. In diabetic patients, concentration of TAT and PIC and fibrinogen were respectively 4.1±2.4 ng/ mL, 362.2±272.0 ng/ mL, 322.7±102.4 mg/ dL in group without vascular complication and 5.3±4.1 ng/ mL, 529.5±258.7 ng/ mL, 374.9±106.2 mg/ dL in group with microvascular complication, which group had increase in PIC and Fibrinogen but no significance after correction of age. Concentration of TAT and PIC and Fibrinogen were 60.±4.9 ng/ mL, 507.4±321.6 ng/ mL, 427.1±194.7 mg/ dL in macrovascular complication, and 10.4±6.7 mg/ mL, 484.8±269.7 ng/ mL, 388.4±132.4 mg/ dL in combined vascular complication which group showed increase of TAT but also had no significant increase after correction of age. 4. In diabetic microvascular complication patients, group of high HbA_1c (>8%) (p=0.049) had significant high PIC concentration. In diabetic macrovascular complication patients, group of high HbA_1c (>8%) (p=0.042) had significant high total cholesterol concentration. 5. In all diabetic patients, PIC was positively correlated with fibrinogen and HbA_1c and negatively correlated BMI (r=0.47, 0.31, -0.25). Only in daibetic patients without angiopathy, TAT was positively correlated with HbA_1c (r=0.67). Conclusion : In this study, plasma TAT and PIC concentration significantly increased in diabetic patients compared with controls, and PIC was increased in group with microvascular complication, TAT were increased in group with combined micro macrovascular complication. However, there was no significance relationship existed when correctinf for age. PIC was correlated with HbA_1c. TAT was correlated with HbA_1c only in the group without angiopathy. Abnormality of coagulation and fibrinolysis were combined in diabetes, plasma TAT and PIC can be used as an index of vascular complication. Also we found the correlation with the degree of the blood glucose control. Therefore we need follow up study for the possibility of prevention of vascular complication after controlling the blood glucose to age-matched patients (J Kor Diaabetes Asso 25:354~363, 2001).

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양웅석,송근암,조몽,이재승,송철수,김형욱,김영민,이수봉,김태오,이성훈 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4

The skin is an uncommon site of distant metastasis from any internal malignancy, and the incidence of metastatic skin lesions as the first symptom of disease is only 0.8% in patients with all systemic malignancies. Furthermore, cutaneous metastasis from adenocarcinoma of the stomach has been found to be extremely rare. A 35-year-old female patient was admitted due to multiple cutaneous nodules in her chest, abdomen, and back. A gastroendoscopic examination and biopsy was made according to the results of skin pathologic findings. Stomach and skin biopsy results revealed a signet ring cell type of adenocarcinoma. A case of gastric adenocarcinoma in which metastatic skin nodules appeared as the first sign of disease, is here in reported with a review of related literature.

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임효영,김인숙,승기배,강동헌,전두수,장기육,박준철,이수영,홍순조,최규보 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8

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이수철,박영철 용인대학교 산업경영연구소 1996 산업경영논총 Vol.1 No.-

The summary of result of empiricial study formulating model for forecasting failures of enterprises is as follws; A case of analysis on ability to forecast failures of enterprises with combined forecasting model The result of analyzing information on stock market and information on business accounting showed that Group 1 was forecasted as sound enterprise while Group 2 and 3 as failures. In consequence compared to forecasting utilizing information on business accounting the forecasting utilizing informtion on stock makret proved to be more superior. Provided that, failures forecasted by means of utilizing information on business accounting were forecasted as sound in Group 1 and Group 2 whereas in Group 3 as forecasted as failure it was proved empirically that the time for failure actually arrived as forecasted. To conclude, compared to the when information on business accounting and information on stock market is solely used for forecasting combined forecasting model is superior. As established by result of conventional study on model for forecasting failure of enterprises combined forecasting model showed highest rate in accurately forecasting failures of enterprises. Furthermore the result of application of this model to Samdo Mulsan Co., Ltd. a subject of this study this firm applied for placement under the charge of legally appointed management company on February 28, 1995 thus classified as under 'Regulation on listing of Securities' thus classified as failed enter

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