http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Lee, Hyunju,Park, Chansu,Lee, Eunkyung,Lee, Ju Dong,Kim, Yangdo American Chemical Society 2017 Journal of chemical and engineering data Vol.62 No.12
<P>HFC-134a gas was investigated as a potential guest molecule to improve the thermodynamic conditions and formation rate for CO<SUB>2</SUB> hydrate. In the phase equilibrium study, the equilibrium pressure of CO<SUB>2</SUB> + HFC-134a was lower than that of pure CO<SUB>2</SUB> gas, and the equilibrium pressure decreased gradually with increasing HFC-134a concentration. The dissociation enthalpy (Δ<I>H</I><SUB>d</SUB>) was calculated using the Clausius–Clapeyron equation, and the Δ<I>H</I><SUB>d</SUB> value also changed with increasing HFC-134a concentration. In particular, the Δ<I>H</I><SUB>d</SUB> of 8 mol % HFC-134a-added CO<SUB>2</SUB> hydrate was 143.2 kJ/mol, which was similar to that of pure HFC-134a (structure-II). In the kinetic study, the reactor was initially filled with CO<SUB>2</SUB> + HFC-134a gas only and pure CO<SUB>2</SUB> gas was then supplied as a source when the hydrate reaction proceeded. As a result, the formation rate of the HFC-134a mixture in the initial 2 min was faster than that of pure CO<SUB>2</SUB>. This was consistent with the gas chromatography results, which showed that HFC-134a occupies the cage at the beginning of hydrate formation. These results suggest that the addition of HFC-134a influences the CO<SUB>2</SUB> hydrate thermodynamic equilibrium and kinetic characteristics.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jceaax/2017/jceaax.2017.62.issue-12/acs.jced.7b00756/production/images/medium/je-2017-007568_0007.gif'></P>
( Chansu Lee ),( Hyuk Lee ),( Seo Yun Hwang ),( Chang Mo Moon ),( Sung Noh Hong ) 대한간학회 2017 Gut and Liver Vol.11 No.6
Background/Aims: Gastric cancer evolves in the pathologic mucosal milieu, and its development is characterized by both the loss of acid-secreting parietal cells and mucosal cell metaplasia, called spasmolytic polypeptide-expressing metaplasia (SPEM). Cytokines, such as interleukin (IL)-10, IL-1β, and IL-6, play a key role in gastric carcinogenesis. However, changes in the cytokine profile of SPEM have not been evaluated. Methods: To induce SPEM in mouse stomachs, C57BL/6 mice were intraperitoneally injected with tamoxifen and sacrificed at 3, 10, and 21 days after treatment. RNA-sequencing (RNA-seq) and a multiplex bead array were used to measure cytokines in the stomachs of tamoxifen-treated/control mice. Results: The administration of tamoxifen led to the rapid development and histological normalization of SPEM 3 and 10 days after administration, respectively. RNA-seq revealed that the expression of IL-10 was decreased 3 days after tamoxifen administration. The multiplex assay identified a significant decline in IL-10 levels 3 days after tamoxifen treatment (58.38±34.44 pg/mL vs 94.09±4.98 pg/mL, p=0.031), which normalized at 10 and 21 days after tamoxifen treatment. Immunofluorescence staining confirmed that IL-10 expression was markedly decreased at the time of SPEM development and subsequently returned to normal, accompanied by a reversal in histologic changes. Conclusions: IL-10 may play a pivotal role in the tamoxifen-induced acute development of gastric SPEM. (Gut Liver 2017;11:789-797)
( Chansu Lee ),( Sung Noh Hong ),( Young-ho Kim ) 대한장연구학회 2020 Intestinal Research Vol.18 No.4
Background/Aims: The modulation of CD1d-restricted natural killer T (NKT) cells by glycolipids has been considered as a potential therapy against immunologic diseases, including inflammatory bowel disease. A recently identified a glycolipid analog, 7DW8-5, which is derived from α-galactosylceramide (α-GalCer), is as much as 100-fold more active at stimulating both human and mice NKT cells when compared to α-GalCer. We explored the effects of 7DW8-5 in mouse models of acute and chronic colitis. Methods: We investigated the effects of 7DW8-5 on intestinal inflammation by assessing the effects of 7dW8-5 on a murine dextran sulfate sodium (DSS)-induced acute colitis model and a chronic colitis-associated tumor model. Results: The acute DSS-induced colitis model showed a dose-dependent response to 7DW8-5, as mice administered 7DW8-5 showed a significant improvement in DSS-induced colitis based on their disease activity index, histologic analysis, and serum C-reactive protein levels, when compared to mice administered vehicle alone. However, DSS-induced colitis in CD1d-KO mice showed no response to 7DW8-5. A fluorescence-activating cell sorting analysis revealed an increase in NKT cells in colonic tissues of 7DW8-5-treated mice. RNA-seq and real-time quantitative polymerase chain reaction showed a significant increase in the expression of interleukin (IL)-4, IL-13, and interferon-gamma in 7DW8-5-treated mice. In addition, 7DW8-5 treatment reduced colitis-associated tumor development in an azoxymethane/DSS mouse model. Conclusions: 7DW8-5 activates NKT cells through CD1d and provides a protective effect against intestinal inflammation in mice. Therefore, 7DW8-5 may be a promising therapeutic agent for treatment of inflammatory bowel disease. (Intest Res 2020;18:402-411)
공공기관 직원의 이직의도에 대한 영향요인 분석 : 신생 과학기술분야 정부출연연구기관을 중심으로
이찬수(Lee, Chansu),김태운(Kim, Taewoon) 한국지방정부학회 2020 지방정부연구 Vol.24 No.2
본 연구에서는 신생 과학기술분야 정부출연연구기관 직원들이 인식하는 보상, 대인관계, 사회적 고립감이 조직몰입 및 이직의도에 미치는 영향과 조직몰입의 매개효과를 분석하였다. 연구결과에 따르면, 첫째, 보상(임금수준)과 동료와의 우호적인 대인관계는 이직의도를 축소할 있으며, 사회적 고립감은 이직의도를 증가시킬 수 있는 것으로 나타났다. 둘째, 보상(임금수준)과 동료와의 우호적인 대인관계는 조직몰입에 정(+)의 영향을 미치는 것으로 나타났으나, 사회적 고립감의 조직몰입에 대한 영향은 유의미하지 않은 것으로 확인되다. 셋째, 보상(임금수준)과 대인관계는 조직몰입의 매개를 통해 이직의도에 영향을 미치고, 사회적 고립감과 이직의도 간의 관계에서 조직몰입은 매개 역할을 하지 않는 것으로 나타났다. 보상, 대인관계, 사회적 고립감은 이직의도에 영향을 미치고, 이중 보상, 대인관계는 조직몰입의 매개를 통해 이직의도에 영향을 미치는 것으로 확인되었다. 이를 고려할 때 신생기관으로서 재직자의 근무연수가 상대적으로 짧은 정부출연연구기관에서는 이직의도를 축소하기 위해 조직 운영과정에서 보상체계와 대인관계의 문제점 발생을 최소화할 필요가 있을 것이다. 또한, 타지 출신 신규 임용자들의 조직 적응을 지원하기 위해 입사일이 비슷한 동료끼리 원활한 사회적 관계가 형성될 수 있는 여건을 조성하고, 정주여건에 대한 관심과 지원을 통해 사회적 고립감이 발생할 수 있는 여지를 축소시킬 필요가 있다. This study analyzed the effects of compensation, interpersonal relations, and social isolation of a new government-funded research institute on organizational commitment and turnover intention and the mediating effects of organizational commitment. According to the results of the study, first, rewards (wage level) and friendly interpersonal relations with colleagues can reduce turnover intentions, and social isolation can increase turnover intentions. Second, rewards (wage level) and friendly interpersonal relationships with peers were found to have a positive effect on organizational commitment, but it was found that the effect of social isolation on organizational commitment was not significant. Third, compensation (wage level) and interpersonal relationships have an effect on turnover intention through mediation of organizational commitment, and organizational commitment does not play a mediating role in the relationship between social isolation and turnover intention. Thus, new government-funded research institutes need to minimize the incidence of compensation systems and interpersonal problems in the organization s operation process in order to reduce turn over intention. Moreover, in order to support the organizational adaptation of new hires from other regions, it is necessary to create conditions for smooth social relations between colleagues with similar employment dates, and to reduce the possibility of social isolation through interest and support for settlement conditions.
채널이 모든 방향으로 산화막 절연된 수직 채널 구조의 단일 셀 메모리-로직 복합 소자(OIC-VFET) 및 집적공정
목찬수(Chansu Mok),이규훈(Gyuhoon Lee),박창준(Changjun Park),김수민(Soomin Kim),이예지(Yeji Lee),구호정(Hojung Goo),김현욱(Hyunwook Kim),김윤재(Yunjae Kim),김성준(Sungjun Kim),조성재(Seongjae Cho),백승재(Seungjae Baik),강명곤(Myounggon 대한전자공학회 2023 대한전자공학회 학술대회 Vol.2023 No.11
Preferential etching of SieSi bond in the microcrystalline silicon germanium
Shinho Kim,Chansu Park,Jung-Chul Lee,Jun-Sik Cho,Yang-Do Kim 한국물리학회 2013 Current Applied Physics Vol.13 No.3
Hydrogenated microcrystalline silicon germanium (mc-Si1-xGex:H) films were investigated as a bottom cell absorber in multi-junction solar cells. mc-Si1-xGex:H films were prepared using very high frequency (VHF, 60 MHz) plasma enhanced chemical vapor deposition (PECVD) systems working pressure of about 1.5 Torr. The precursor flow rates were carefully controlled to determine the phase transition point and to improve the crystallinity of mc-Si1-xGex:H. A relatively high plasma power was necessary to have the high hydrogen (H2) dilution. Raman spectroscopy study showed transition steps from amorphous to microstructure morphology as hydrogen dilution increasing. Crystallite SieGe and GeeGe bonds were occurred at relatively higher H2 dilution compare to crystallite SieSi bond. The rapidly increased Ge content as increasing the H2 dilution is believed mainly due to the different decomposition rate of silane (SiH4) and germane (GeH4). The other reason of high Ge content even at the low GeH4 precursor flow rate is probably due to the preferential etching of silicon atom by H2. The preferential etching of SieH possibly occurred in very highly concentrated H2 plasma due to the preferential attachment of SieH. The compositions of mc-Si1-xGex:H films measured using RBS were Si0.83Ge0.17, Si0.67Ge0.33 and Si0.59Ge0.41 at H2/SiH4 flow rate of 60, 80 and 100, respectively. mc-Si1-xGex:H films showed the dark (sd) and photo conductivity (sp) of about 107 and 10-5 S/cm, respectively and photo response (sp/sd) was about 102. This study will present the comprehensive evaluation of crystallization behavior of mc-Si1-xGex:H films.