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장애가 있는 바리스타를 위한 작업 동선을 최소화하는 작업 공간 배치에 관한 연구: 유전 알고리즘의 응용
김우성 ( Kim¸ Woo-sung ),박경수 ( Park¸ Kyungsu ) 한국경영공학회 2021 한국경영공학회지 Vol.26 No.3
Purpose The goal is to find an optimal workspace design for the convenience of workers and improvement of the work environment in coffee shops where mentally disabled people perform their duties as baristas. Methods A genetic algorithm is applied to find the optimal arrangement, and chromosome representation, chromosome variation, and crossover operations are presented. Results By applying the algorithm using the actual data, it was found that the optimal layout reduces the total movement of a worker by 50% compared to the existing one. Conclusion The results illustrate that the method can help to reduce the fatigue of the worker since total movement of a worker can be reduced.
정우성 ( Jung¸ Woo-sung ) 한국구조물진단유지관리공학회 2009 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.13 No.1
For security of dam safety, a variety of expert skills such as geotechnical engineering, structural engineering, geology, hydraulics, hydrology, mechanical engineering, electricity, environmental engineering and so on are needed. So, it is important to develop the guideline which is easy to understand and available. Especially, the guideline for dam safety could provide the information about the items which are considered in case of design, construction and post-construction and could increase the life of the existing dam by the proper management actions. The purpose of this research is to develop the technical guideline for dam safety, which is needed to prevent the dam safety problems and mitigate the disaster risk for dam safety, and to recommend the skill for investigation, analysis and application included in the developed guideline.
Woosung Shin,Jeongyeon Yoon,Goo Taeg Oh,Sungwoo Ryoo 고려인삼학회 2013 Journal of Ginseng Research Vol.37 No.1
Korean red ginseng water extract (KG-WE) has known beneficial effects on the cardiovascular system via inducting nitric oxide (NO) production in endothelium. Endothelial arginase inhibits the activity of endothelial nitric oxide synthase (eNOS) by substrate depletion, thereby reducing NO bioavailability and contributing to vascular diseases including hypertension, aging, and atherosclerosis. In the present study, we demonstrate that KG-WE inhibits arginase activity and negatively regulates NO production and reactive oxygen species generation in endothelium. This is associated with increased dimerization of eNOS without affecting the protein expression levels of either arginase or eNOS. In a vascular tension assay, when aortas isolated from wild type mice were incubated with KG-WE, NO-dependent enhanced vasorelaxation was observed. Furthermore, KG-WE administered via by drinking water to atherogenic model mice being fed high cholesterol diet improved impaired vascular function. Taken together, these results suggest that KG-WE may exert vasoprotective effects through augmentation of NO signaling by inhibiting arginase. Therefore, KG-WE may be useful in the treatment of vascular diseases derived from endothelial dysfunction, such as atherosclerosis.